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https://www.readbyqxmd.com/read/29332120/severe-loss-of-tritan-color-discrimination-in-rpe65-associated-leber-congenital-amaurosis
#1
Neruban Kumaran, Caterina Ripamonti, Angelos Kalitzeos, Gary S Rubin, James W B Bainbridge, Michel Michaelides
Purpose: RPE65-associated Leber congenital amaurosis (RPE65-LCA) is a progressive severe retinal dystrophy with early profound dysfunction of rod photoreceptors followed by progressive cone photoreceptor degeneration. We aim to provide detailed information about how cone dysfunction affects color discrimination. Methods: Seven adults (aged 16-21) with RPE65-LCA underwent monocular color discrimination assessment using the Trivector and Ellipse versions of three computerized tests: Cambridge Colour Test (CCT), low vision version of the Cambridge Colour Test (lvvCCT), and the Universal Colour Discrimination Test (UCDT)...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29330587/posterior-reversible-encephalopathy-syndrome-with-spinal-cord-involvement-pres-sci-as-a-rare-complication-of-severe-diabetic-ketoacidosis-a-case-report-and-review-of-the-literature
#2
Jianfei Nao, Han Zhang, Si Wu, Xiaotian Zhang, Dongming Zheng
INTRODUCTION: In addition to diffuse brain oedema, diabetic ketoacidosis (DKA) can lead to ischaemic or haemorrhagic stroke, extrapontine myelinolysis, and sinovenous thrombosis. However, posterior reversible encephalopathy syndrome (PRES) and spinal cord oedema are rarely reported in patients with DKA. METHODS: We present a case of a 17-year-old-girl who developed headache, blurred vision, and paraplegia after her DKA was controlled. Sequential magnetic resonance (MR) scans of the brain and spinal cord were performed...
January 12, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29329054/relationship-between-sedentary-behavior-and-depression-a-mediation-analysis-of-influential-factors-across-the-lifespan-among-42-469-people-in-low-and-middle-income-countries
#3
Brendon Stubbs, Davy Vancampfort, Joseph Firth, Felipe B Schuch, Mats Hallgren, Lee Smith, Benjamin Gardner, Kai G Kahl, Nicola Veronese, Marco Solmi, André F Carvalho, Ai Koyanagi
BACKGROUND: Sedentary behavior (SB) is associated with diabetes, cardiovascular disease and low mood. There is a paucity of multi-national research investigating SB and depression, particularly among low- and middle-income countries. This study investigated the association between SB and depression, and factors which influence this. METHODS: Cross-sectional data were analyzed from the World Health Organization's Study on Global Ageing and Adult Health. Depression was based on the Composite International Diagnostic Interview...
January 3, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29328958/stdp-based-spiking-deep-convolutional-neural-networks-for-object-recognition
#4
Saeed Reza Kheradpisheh, Mohammad Ganjtabesh, Simon J Thorpe, Timothée Masquelier
Previous studies have shown that spike-timing-dependent plasticity (STDP) can be used in spiking neural networks (SNN) to extract visual features of low or intermediate complexity in an unsupervised manner. These studies, however, used relatively shallow architectures, and only one layer was trainable. Another line of research has demonstrated - using rate-based neural networks trained with back-propagation - that having many layers increases the recognition robustness, an approach known as deep learning. We thus designed a deep SNN, comprising several convolutional (trainable with STDP) and pooling layers...
December 23, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29327689/global-spectral-graph-wavelet-signature-for-surface-analysis-of-carpal-bones
#5
Majid Masoumi, Mahsa Rezaei, A Ben Hamza
Quantitative shape comparison is a fundamental problem in computer vision, geometry processing and medical imaging. In this paper, we present a spectral graph wavelet approach for shape analysis of carpal bones of the human wrist. We employ spectral graph wavelets to represent the cortical surface of a carpal bone via the spectral geometric analysis of the Laplace-Beltrami operator in the discrete domain. We propose global spectral graph wavelet (GSGW) descriptor that is isometric invariant, efficient to compute, and combines the advantages of both low-pass and band-pass filters...
January 12, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29325403/economic-inequality-in-presenting-vision-in-shahroud-iran-two-decomposition-methods
#6
Asieh Mansouri, Mohammad Hassan Emamian, Hojjat Zeraati, Hasan Hashemi, Akbar Fotouhi
BACKGROUND: Visual acuity, like many other health-related problems, does not have an equal distribution in terms of socio-economic factors. We conducted this study to estimate and decompose economic inequality in presenting visual acuity using two methods and to compare their results in a population aged 40-64 years in Shahroud, Iran. METHODS: The data of 5188 participants in the first phase of the Shahroud Cohort Eye Study, performed in 2009, were used for this study...
April 22, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/29324929/our-solution-for-fusion-of-simultaneusly-acquired-whole-body-scintigrams-and-optical-images-as-usesful-tool-in-clinical-practice-in-patients-with-differentiated-thyroid-carcinomas-after-radioiodine-therapy-a-useful-tool-in-clinical-practice
#7
Milovan Matovic, Milica Jankovic, Marko Barjaktarovic, Marija Jeremic
OBJECTIVE: After radioiodine therapy of differentiated thyroid cancer (DTC) patients, whole body scintigraphy (WBS) is standard procedure before releasing the patient from the hospital. A common problem is the precise localization of regions where the iod-avide tissue is located. Sometimes is practically impossible to perform precise topographic localization of such regions. METHOD: In order to face this problem, we have developed a low-cost Vision-Fusion system for web-camera image acquisition simultaneously with routine scintigraphic whole body acquisition including the algorithm for fusion of images given from both cameras...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29324415/convolutional-sparse-coding-for-rgb-nir-imaging
#8
Xuemei Hu, Felix Heide, Qionghai Dai, Gordon Wetzstein
Emerging sensor designs increasingly rely on novel color filter arrays (CFAs) to sample the incident spectrum in unconventional ways. In particular, capturing a near-infrared (NIR) channel along with conventional RGB color is an exciting new imaging modality. RGB+NIR sensing has broad applications in computational photography, such as low-light denoising, it has applications in computer vision, such as facial recognition and tracking, and it paves the way toward low-cost single-sensor RGB and depth imaging using structured illumination...
April 2018: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/29319875/association-between-sensory-impairment-and-dementia-in-older-adults-evidence-from-china
#9
Yanan Luo, Ping He, Chao Guo, Gong Chen, Ning Li, Xiaoying Zheng
OBJECTIVES: To determine the association between sensory impairment and dementia in Chinese older adults. DESIGN: Cross-sectional. SETTING: Older adults in 31 provinces of China. PARTICIPANTS: Individuals aged 65 and older (N = 250,752). MEASUREMENTS: Psychiatrists ascertained dementia based on the International Classification of Diseases, 10th Revision. Sensory impairment was measured as only hearing impairment, only vision impairment, and combined sensory impairment (combined hearing and vision impairment)...
January 10, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29318381/-evaluation-of-the-medical-treatment-situation-of-the-visually-impaired-significant-differences-between-young-and-old
#10
M Oeverhaus, H Hirche, J Esser, A Eckstein, B Schaperdoth-Gerlings
BACKGROUND AND OBJECTIVE: Patients with irreversible visual impairment need individual visual rehabilitation to regain or improve reading ability and mobility. To analyze the prescription of low vision aids (LVA) and their relation to age, we performed a retrospective chart analysis of our specialized low vision outpatient clinic. METHODS: Patient charts of all patients who attended our low vision outpatient clinic from 2014-2016 were analyzed with respect to the diagnosis, visual acuity, magnification needs, age and prescribed or used LVA...
January 9, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29315796/the-association-of-self-reported-diabetes-with-impaired-social-functioning-in-low-middle-and-high-income-countries-findings-from-the-world-health-survey
#11
A Loerbroks, R M Herr, A Icks, J A Bosch
AIM: Epidemiological studies from high-income countries show that diabetes is associated with impaired social functioning. As healthcare systems in middle- and low-income countries offer fewer resources to curtail the potential social impact of diabetes, we performed a comparative study on the diabetes-social impairment link in low-, middle- and high-income countries. METHODS: We use data from the cross-sectional World Health Survey (n = 235 428 from 10 low-income, 29 middle-income and 9 high-income countries)...
January 7, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29313167/prenatal-exposure-to-chernobyl-fallout-in-norway-neurological-and-developmental-outcomes-in-a-25-year-follow-up
#12
Rolv Terje Lie, Dag Moster, Per Strand, Allen James Wilcox
Ionizing radiation at high doses early in life may cause neurodevelopmental problems. Possible effects of lower doses are, however, controversial. We use carefully collected exposure data for Norway following the Chernobyl accident in April 1986 combined with population-based registries to assess long-term effects of fetal exposure on neurodevelopmental outcomes. Radiation doses were estimated for each Norwegian municipality for each calendar month from May 1986 to April 1989. We established a cohort of all Norwegian pregnancies during the three-year period of radiation measurement and compared them with appropriate unexposed groups...
January 8, 2018: European Journal of Epidemiology
https://www.readbyqxmd.com/read/29311034/caregiving-for-uganda-s-elders-with-disability-using-cross-sectional-surveillance-data-to-identify-healthcare-service-gaps-in-low-and-middle-income-settings
#13
Abdulgafoor M Bachani, Jacob A Bentley, Nukhba Zia, Edward Galiwango, Jeremiah Lum, Gulnar Tuli, Shuen-En Ho
BACKGROUND: Disability is highly prevalent in low-and-middle-income countries (LMICs), but there is a relative dearth of disability and caregiving research from LMICs. OBJECTIVE: To examine type and severity of disability experienced by individuals 60 years and older, caregivers and type of caregiving assistance, and the interrelationships between sociodemographic factors involved in Uganda. METHODS: Data was collected from two Eastern Ugandan districts using the WHO Disability Assessment Schedule 2...
December 31, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/29310343/cerebrospinal-fluid-real-time-quaking-induced-conversion-test-for-sporadic-creutzfeldt-jakob-disease-in-an-18-year-old-woman-a-case-report
#14
Yuan Yao, Xiaoping Dong, Hongzhi Guan, Qiang Lu
RATIONALE: Sporadic Creutzfeldt-Jakob disease (sCJD) mainly occurs in the elderly, with the peak age of onset ranging from 55 to 75 years. The symptoms of sCJD are not unique, and laboratory tests such as magnetic resonance imaging (MRI), electroencephalogram (EEG) and cerebrospinal fluid (CSF)14-3-3 protein have low sensitivity or specificity. Therefore, excluding treatable diseases and establishing a diagnosis could be difficult in young patients with suspected sCJD. Recently, real-time quaking-induced conversion (RT-QuIC) has been used in the diagnosis of sCJD, with more than 95% sensitivity and 100% specificity...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29306320/infection-dynamics-and-tissue-tropism-of-parvicapsula-pseudobranchicola-myxozoa-myxosporea-in-farmed-atlantic-salmon-salmo-salar
#15
Are Nylund, Haakon Hansen, Øyvind J Brevik, Håvard Hustoft, Turhan Markussen, Heidrun Plarre, Egil Karlsbakk
BACKGROUND: The myxosporean parasite Parvicapsula pseudobranchicola commonly infects farmed Atlantic salmon in northern Norway. Heavy infections are associated with pseudobranch lesions, runting and mortality in the salmon populations. The life-cycle of the parasite is unknown, preventing controlled challenge experiments. The infection dynamics, duration of sporogony, tissue tropism and ability to develop immunity to the parasite in farmed Atlantic salmon is poorly known. We conducted a field experiment, aiming at examining these aspects...
January 6, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29305684/an-extraaxially-localized-intrasellar-giant-hydatid-cyst-with-hypophyseal-insufficiency
#16
Gökhan Çavuş, Vedat Açik, Yeliz Çavuş, Emre Bilgin, Yurdal Gezercan, Ali Ihsan Ökten
PURPOSE: A hydatid cyst is a parasitic illness that is caused by the larvae of Echinococcus granulosus. Hydatid cysts occur in the liver in 75% and in the lungs in 15% of cases. Central nervous system involvement is rare (perhaps as low as 1%), and the majority of such cases are observed in children. Headache and vomiting are the most frequently observed symptoms. In patients diagnosed with a hydatid cyst, imaging methods and serologic tests are very important for identifying cranial involvement...
January 5, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29304251/the-role-of-leadership-in-people-centred-health-systems-a-sub-national-study-in-the-gambia
#17
Simukai Chigudu, Momodou Jasseh, Umberto d'Alessandro, Tumani Corrah, Adama Demba, Julie Balen
Recently, increasing attention has been given to behavioural and relational aspects of the people who both define and shape health systems, placing them at the core. A growing refrain includes the assertion that important decisions determining health system performance, including agenda setting, policy formulation and policy implementation, are made by people. Within this actor-oriented approach, good leadership has been identified as a key contributing factor in health systems strengthening. However, leadership remains ill-defined and under-researched, especially in resource-limited settings, and understanding the links between leadership and health outcomes remains a challenge...
January 1, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29303163/ar4vi-ar-as-an-accessibility-tool-for-people-with-visual-impairments
#18
James M Coughlan, Joshua Miele
Although AR technology has been largely dominated by visual media, a number of AR tools using both visual and auditory feedback have been developed specifically to assist people with low vision or blindness - an application domain that we term Augmented Reality for Visual Impairment (AR4VI). We describe two AR4VI tools developed at Smith-Kettlewell, as well as a number of pre-existing examples. We emphasize that AR4VI is a powerful tool with the potential to remove or significantly reduce a range of accessibility barriers...
October 2017: Int Symp Mix Augment Real
https://www.readbyqxmd.com/read/29300676/intracranial-hypotension-mimicking-chronic-progressive-external-ophthalmoplegia
#19
Kaveh Vahdani, Katherine McVeigh, Rhys Harrison, Mandy Williams, Helen Garrott
Intracranial hypotension (ICH) is characterized by low cerebrospinal fluid pressure, postural headaches, and diffuse pachymeningeal enhancement on magnetic resonance imaging (MRI). A variety of ophthalmoparetic manifestations have been reported in the context of the ICH. The authors describe an unusual case of a 64-year-old woman who presented with rapid onset of headaches, bilateral upper-lid ptosis, and blurring of vision within 4 days after sustaining a trivial head injury. She was noted to have bilateral symmetrical ophthalmoplegia and ptosis-simulating chronic progressive external ophthalmoplegia...
January 4, 2018: Orbit
https://www.readbyqxmd.com/read/29286865/randomized-controlled-study-to-evaluate-the-efficacy-of-adalimumab-in-patients-with-different-forms-of-refractory-uveitis
#20
Friederike Mackensen, Carsten Heinz, Eva Jakob, Viviane Grewing, Hanns-Martin Lorenz, Arnd Heiligenhaus, Regina Max, Matthias D Becker
PURPOSE: TNF alpha inhibitors have revolutionized the care of vision-threatening uveitis. This study evaluated the efficacy of adalimumab (ADA) for the treatment of refractory noninfectious uveitis. DESIGN: Randomized, prospective, controlled, two-center clinical trial Methods: Patients with active uveitis despite combined oral low-dose prednisolone and immunosuppression were randomized for additional ADA with corticosteroids in a fixed tapering regime, or corticosteroids only...
December 29, 2017: Ocular Immunology and Inflammation
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