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Rebecca R Best, Benjamin H L Harris, Jason L Walsh, Timothy Manfield
OBJECTIVES: Drowning is one of the leading causes of death in children. Resuscitating a child following submersion is a high-pressure situation, and standard operating procedures can reduce error. Currently, the Resuscitation Council UK guidance does not include a standard operating procedure on pediatric drowning. The objective of this project was to design a standard operating procedure to improve outcomes of drowned children. METHODS: A literature review on the management of pediatric drowning was conducted...
May 8, 2017: Pediatric Emergency Care
Abbas Abbas, Sagar Kadakia, Vishnu Ambur, Kimberly Muro, Larry Kaiser
BACKGROUND: Localizing small or deep pulmonary nodules or subsolid ground-glass opacities often is difficult during video-assisted thoracoscopic surgery (VATS) or robotic-assisted thoracoscopic surgery (RATS). This can result in larger resections or conversion to thoracotomy. The goal of this study is to evaluate the role of electromagnetic navigational bronchoscopic localization (ENBL) as a safe and accurate intraoperative method to localize small, deep, or subsolid nodules. METHODS: This is a single-institution, single-surgeon retrospective study of all patients (51) who underwent combined ENBL and resection of 54 nodules between May 2013 and August 2015...
February 7, 2017: Journal of Thoracic and Cardiovascular Surgery
Ajay Narasimhan, Shivanraj Ayyanathan, Late Rajavenkatesh Krishnamoorthy
A 14-year-old boy came to our outpatient department with pleuritic chest pain and dyspnea. He was found to have a loculated empyema on the right side. He was taken up for surgery and decortication was done. He developed air leak in the postoperative period. When the air leak did not settle until the 10(th) day, we decided to attach the atrium Pneumostat(™), a modified version of the Heimlich valve to his Intercostal drainage tube and sent him home. On further follow-up, his lung expanded, and ICD could be removed...
January 2017: Lung India: Official Organ of Indian Chest Society
Joseph Barnett, Aniket N Tavare, Sajid Khan, Ashish Saini, Dean D Creer, Samanjit S Hare
PURPOSE: Patients with thoracic malignancies often have more than one site of pulmonary, nodal or pleural disease within one hemithorax. In addition, large heterogeneous lesions may comprise distinct, mixed pathological entities. Histological analysis of these lesions can alter tumour staging and treatment options. We investigated the feasibility, safety and benefit of performing image-guided percutaneous lung biopsy (PLB) of two lesions in the same hemithorax at a single sitting. MATERIALS AND METHODS: Ten consecutive outpatients with two or more potential disease foci within the same hemithorax were analysed over a 15-month period...
May 2017: Cardiovascular and Interventional Radiology
Bob Roehr
No abstract text is available yet for this article.
January 9, 2017: BMJ: British Medical Journal
Roxann Diez Gross, Ronit Gisser, Gregory Cherpes, Katie Hartman, Rishi Maheshwary
Prader-Willi Syndrome (PWS) is caused by a genetic imprinting abnormality resulting from the lack of expression of the paternal genes at 15q11-q13. Intellectual disability, low muscle tone, and life-threatening hyperphagia are hallmarks of the phenotype. The need for the Heimlich maneuver, death from choking, and pulmonary infection occur in a disproportionally high number of persons with PWS. The widely held belief is that eating behaviors are responsible for choking and aspiration; yet, no investigation had sought to determine if swallowing impairments were present in persons with PWS...
February 2017: American Journal of Medical Genetics. Part A
D A Rund
Choking results in many deaths each year. Yet a simple procedure that can be performed by almost anyone, even the victims, could prevent this from happening.
December 1989: Physician and Sportsmedicine
Christopher C Stanley, Kate D Westmoreland, Brett J Heimlich, Nader K El-Mallawany, Peter Wasswa, Idah Mtete, Mercy Butia, Salama Itimu, Mary Chasela, Mary Mtunda, Mary Chikasema, Victor Makwakwa, Bongani Kaimila, Edwards Kasonkanji, Fred Chimzimu, Coxcilly Kampani, Bal M Dhungel, Robert Krysiak, Nathan D Montgomery, Yuri Fedoriw, Nora E Rosenberg, N George Liomba, Satish Gopal
Burkitt lymphoma (BL) is the most common paediatric cancer in sub-Saharan Africa (SSA). Anthracyline-based treatment is standard in resource-rich settings, but has not been described in SSA. Children ≤18 years of age with newly diagnosed BL were prospectively enrolled from June 2013 to May 2015 in Malawi. Staging and supportive care were standardized, as was treatment with CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) for six cycles. Among 73 children with BL, median age was 9·2 years (interquartile range 7·7-11·8), 48 (66%) were male and two were positive for human immunodeficiency virus...
June 2016: British Journal of Haematology
Anne Schneibel, Marion Stellmes, Achim Röder, Manfred Finckh, Rasmus Revermann, David Frantz, Joachim Hill
The repopulation of abandoned areas in Angola after 27years of civil war led to a fast and extensive expansion of agricultural fields to meet the rising food demand. Yet, the increase in crop production at the expense of natural resources carries an inherent potential for conflicts since the demand for timber and wood extraction are also supposed to rise. We use the concept of ecosystem services to evaluate the trade-off between food and woody biomass. Our study area is located in central Angola, in the highlands of the upper Okavango catchment...
April 1, 2016: Science of the Total Environment
Matteo Bruschettini, Olga Romantsik, Luca Antonio Ramenghi, Simona Zappettini, Colm P F O'Donnell, Maria Grazia Calevo
BACKGROUND: Pneumothorax occurs more frequently in the neonatal period than at any other time of life and is associated with increased mortality and morbidity. It may be treated with either needle aspiration or insertion of a chest tube. The former consists of aspiration of air with a syringe through a needle or an angiocatheter, usually through the second or third intercostal space in the midclavicular line. The chest tube is usually placed in the anterior pleural space passing through the sixth intercostal space into the pleural opening, turned anteriorly and directed to the location of the pneumothorax, and then connected to a Heimlich valve or an underwater seal with continuous suction...
January 11, 2016: Cochrane Database of Systematic Reviews
Perzila Ara, Shaokoon Cheng, Michael Heimlich, Eryk Dutkiewicz
Recent developments in capsule endoscopy have highlighted the need for accurate techniques to estimate the location of a capsule endoscope. A highly accurate location estimation of a capsule endoscope in the gastrointestinal (GI) tract in the range of several millimeters is a challenging task. This is mainly because the radio-frequency signals encounter high loss and a highly dynamic channel propagation environment. Therefore, an accurate path-loss model is required for the development of accurate localization algorithms...
2015: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Alistair Harrison, Laura G Dubois, Lisa St John-Williams, M Arthur Moseley, Rachael L Hardison, Derek R Heimlich, Alexander Stoddard, Joseph E Kerschner, Sheryl S Justice, J Will Thompson, Kevin M Mason
A thorough understanding of the molecular details of the interactions between bacteria and host are critical to ultimately prevent disease. Recent technological advances allow simultaneous analysis of host and bacterial protein and metabolic profiles from a single small tissue sample to provide insight into pathogenesis. We used the chinchilla model of human otitis media to determine, for the first time, the most expansive delineation of global changes in protein and metabolite profiles during an experimentally induced disease...
March 2016: Molecular & Cellular Proteomics: MCP
Samuel S Kim, Zain Khalpey, Sherry L Daugherty, Mohammad Torabi, Alex G Little
BACKGROUND: This study determined patterns of chest tube (CT) selection and management after open lobectomy and minimally invasive lobectomy by thoracic surgeons. METHODS: Surveys were sent electronically to 5,175 thoracic surgeons, and 475 were completed. Responses, blinded so individuals could not be identified, were analyzed and compared according to surgeon characteristics (academic/private practice, years in practice, lobectomy volume, and geographic region)...
March 2016: Annals of Thoracic Surgery
J Brett Heimlich, Joshua S Speed, Paul M O'Connor, Jennifer S Pollock, Tim M Townes, Steffen E Meiler, Abdullah Kutlar, David M Pollock
BACKGROUND AND PURPOSE: Endothelin-1 (ET-1) is increased in patients with sickle cell disease and may contribute to the development of sickle cell nephropathy. The current study was designed to determine whether ET-1 acting via the ETA receptor contributes to renal injury in a mouse model of sickle cell disease. EXPERIMENTAL APPROACH: Adult, humanized HbSS (homozygous for sickle Hb) mice had increased ET-1 mRNA expression in both the cortex and the glomeruli compared with mice heterozygous for sickle and Hb A (HbAS controls)...
January 2016: British Journal of Pharmacology
J V Pai-Dhungat, Falguni Parikh
No abstract text is available yet for this article.
March 2015: Journal of the Association of Physicians of India
Joshua S Broder, James W Fox, Judy Milne, Brent Jason Theiling, Ann White
Medical errors are commonly multifactorial, with adverse clinical consequences often requiring the simultaneous failure of a series of protective layers, termed the Swiss Cheese model. Remedying and preventing future medical errors requires a series of steps, including detection, mitigation of patient harm, disclosure, reporting, root cause analysis, system modification, regulatory action, and engineering and manufacturing reforms. We describe this process applied to two cases of improper orientation of a Heimlich valve in a thoracostomy tube system, resulting in enlargement of an existing pneumothorax and the development of radiographic features of tension pneumothorax...
April 2016: Emergency Medicine Journal: EMJ
Joshua S Speed, J Brett Heimlich, Kelly A Hyndman, Brandon M Fox, Vivek Patel, Masashi Yanagisawa, Jennifer S Pollock, Jens M Titze, David M Pollock
The current study was designed to determine whether vascular endothelial-derived endothelin-1 (ET-1) is important for skin Na(+) buffering. In control mice (C57BL/6J), plasma Na(+) and osmolarity were significantly elevated in animals on high- vs. low-salt (HS and LS, respectively) intake. The increased plasma Na(+) and osmolarity were associated with increased ET-1 mRNA in vascular tissue. There was no detectable difference in skin Na(+):H2O in HS fed mice (0.119 ± 0.005 mM vs. 0.127 ± 0.007 mM; LS vs. HS); however, skin Na(+):H2O was significantly increased by blockade of the endothelin type A receptor with ABT-627 (0...
December 2015: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
A N Tavare, D D Creer, S Khan, R Vancheeswaran, S S Hare
A prospective study of 489 consecutive outpatient image-guided percutaneous lung biopsies was conducted to determine whether early discharge, incorporating ambulatory Heimlich valve drain, is potentially advantageous to the National Health Service. Patients were discharged at 30 or 60 min, with significant pneumothoraces treated using Heimlich valve. 485 (99.2%) patients were successfully discharged early, 402 at 30 min. 87 (17.8%) patients developed pneumothorax: 52 required Heimlich valve; 5 proceeded to biopsy with Heimlich valve in situ...
February 2016: Thorax
Oliver J Bintcliffe, Rob J Hallifax, Anthony Edey, David Feller-Kopman, Y C Gary Lee, Charles H Marquette, Jean-Marie Tschopp, Douglas West, Najib M Rahman, Nick A Maskell
There are substantial differences in international guidelines for the management of pneumothorax and much geographical variation in clinical practice. These discrepancies have, in part, been driven by a paucity of high-quality evidence. Advances in diagnostic techniques have increasingly allowed the identification of lung abnormalities in patients previously labelled as having primary spontaneous pneumothorax, a group in whom recommended management differs from those with clinically apparent lung disease. Pathophysiological mechanisms underlying pneumothorax are now better understood and this may have implications for clinical management...
July 2015: Lancet Respiratory Medicine
Marie Godet, Jérôme Chevillotte
No abstract text is available yet for this article.
May 2015: Revue de L'infirmière
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