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https://www.readbyqxmd.com/read/27921048/surgical-treatment-of-metabolic-syndrome
#1
REVIEW
Norbert Runkel, Rainer Brydniak
BACKGROUND: Bariatric surgery is gastrointestinal surgery for weight control, and metabolic surgery refers to the use of surgery to primarily and purposely treat type 2 diabetes mellitus (T2DM)/metabolic syndrome mellitus. METHODS: The most recent literature was reviewed for surgery and T2DM in a non-systematic fashion. RESULTS: Roux-Y gastric bypass, biliopancreatic diversion with duodenal switch, and sleeve gastrectomy (SG) are the dominant procedures today...
October 2016: Visceral Medicine
https://www.readbyqxmd.com/read/27902700/plasma-lactoferrin-levels-positively-correlate-with-insulin-resistance-despite-an-inverse-association-with-total-adiposity-in-lean-and-severely-obese-patients
#2
Sylvain Mayeur, Alain Veilleux, Yves Pouliot, Benoît Lamarche, Jean-François Beaulieu, Frédéric S Hould, Denis Richard, André Tchernof, Emile Levy
CONTEXT: Lactoferrin (Lf) is an important protein found on mucosal surfaces, within neutrophils and various cells, and in biological fluids. It displays multiple functions, including iron-binding as well as antimicrobial, immunomodulatory and anti-inflammatory activities. Although Lf ingestion has been suggested to cause adiposity reduction in murine models and humans, its relationship with insulin resistance (IR) has not been studied thoroughly. OBJECTIVE: To establish the association between circulating Lf levels, glucose status and blood lipid/lipoprotein profile...
2016: PloS One
https://www.readbyqxmd.com/read/27896648/clinical-and-metabolic-effects-of-biliopancreatic-diversion-persist-after-reduction-of-the-gastric-pouch-and-elongation-of-the-common-alimentary-tract-preliminary-report-in-a-series-of-patients-with-a-10-year-follow-up
#3
Valerio Ceriani, Francesco Cetta, Tiziana Lodi, Ferdinando Pinna, Antonio E Pontiroli
BACKGROUND: Biliopancreatic diversion (BPD) is a bariatric technique burdened, in some instances, by clinical evidence of malabsorption and malnutrition, and by intractable diarrhea. OBJECTIVE: The objective of this study was to assess metabolic and nutritional effects on patients undergoing BPD and BPD plus revisional surgery because of side effects. METHODS: Thirty-five consecutive BPD patients underwent revisional surgery (elongation of the common limb from 50 to 200 cm and reduction of the gastric pouch from 500 to 40 ml) after a median 48-month period [48...
November 29, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27878276/expression-pattern-of-hmgb1-and-its-association-with-autophagy-in-acute-necrotizing-pancreatitis
#4
Can Yu, Xiao Yu, Hong-Wei Zhu, Xia Li, Li-Hua Huang, Zhi-Qiang Li, Duo Han, Hui Huang
High-motility group box protein 1 (HMGB1) has an important role in autophagy; however, its exact role in acute necrotizing pancreatitis (ANP) remains unknown. The present study aimed to investigate the expression pattern of HMGB1 in ANP, and to determine its association with autophagy. Sprague Dawley rats (weight, 350±30 g, n=48) were randomly divided into control (n=12) and experimental (n=36) groups. Experimental rats were retrogradely injected with 5% sodium taurocholate into the biliopancreatic duct to induce ANP...
November 15, 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27861546/early-parenteral-nutrition-in-patients-with-biliopancreatic-mass-lesions-a-prospective-randomized-intervention-trial
#5
Janine Krüger, Peter J Meffert, Lena J Vogt, Simone Gärtner, Antje Steveling, Matthias Kraft, Julia Mayerle, Markus M Lerch, Ali A Aghdassi
PURPOSE: Patients with biliopancreatic tumors frequently suffer from weight loss and cachexia. The in-hospital work-up to differentiate between benign and malignant biliopancreatic lesions requires repeated pre-interventional fasting periods that can aggravate this problem. We conducted a randomized intervention study to test whether routine in-hospital peripheral intravenous nutrition on fasting days (1000 ml/24 h, 700 kcal) has a beneficial effect on body weight and body composition...
2016: PloS One
https://www.readbyqxmd.com/read/27814663/change-in-fracture-risk-and-fracture-pattern-after-bariatric-surgery-nested-case-control-study
#6
Catherine Rousseau, Sonia Jean, Philippe Gamache, Stéfane Lebel, Fabrice Mac-Way, Laurent Biertho, Laëtitia Michou, Claudia Gagnon
OBJECTIVE:  To investigate whether bariatric surgery increases the risk of fracture. DESIGN:  Retrospective nested case-control study. SETTING:  Patients who underwent bariatric surgery in the province of Quebec, Canada, between 2001 and 2014, selected using healthcare administrative databases. PARTICIPANTS:  12 676 patients who underwent bariatric surgery, age and sex matched with 38 028 obese and 126 760 non-obese controls...
July 27, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27803771/efficacy-and-safety-of-endoscopic-papillary-balloon-dilation-for-the-removal-of-bile-duct-stones-data-from-a-real-life-multicenter-study-on-dilation-assisted-stone-extraction
#7
Roberto Di Mitri, Filippo Mocciaro, Socrate Pallio, Giulia Maria Pecoraro, Andrea Tortora, Claudio Zulli, Simona Attardo, Attilio Maurano
AIM: To report data on Dilation-Assisted Stone Extraction (DASE) use in clinical practice and its efficacy and safety trough three Italian referral centers for biliopancreatic diseases treatment. METHODS: From January 2011 to December 2015 we collected data on 120 patients treated with DASE. Technical success was obtained when the endoscopist was able to place the balloon trough the papilla inflating the balloon until the final diameter for an adequate time (at least 30 s)...
October 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27801414/-incretin-secretion-and-glucose-metabolism-in-morbidly-obese-patients-in-the-early-and-late-periods-after-biliopancreatic-diversion
#8
I I Dedov, G A Mel'nichenko, E A Troshina, E V Ershova, N V Mazurina, N A Ogneva, Yu I Yashkov, A V Il'in
AIM: To estimate the parameters of glucose metabolism and to assess the secretion of incretins in patients after biliopancreatic diversion (BPD) for morbid obesity (MO) in the early and late postoperative periods. SUBJECTS AND METHODS: The prospective part of the investigation included 22 patients with a body mass index of 35.8 to 68.4 kg/m2 and type 2 diabetes mellitus (T2DM). All the patients were examined before, 3 weeks and 3 months after BPD. The retrospective part covered 23 patients who were examined after BPD for MO; the postoperative period was 4...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27795771/-role-of-biliary-mri-in-etiological-diagnosis-of-cholestatic-icteruses-in-dakar
#9
Nfally Badji, Geraud Akpo, Hamidou Deme, Mouhamadou Hamine Toure, Mamadou Ly, Boucar Ndong, El Hadji Niang
Biliary MRI is a relatively new diagnostic test in the arsenal of exploration techniques in biliopancreatic pathology. This is a reproducible and reliable non invasive technique for direct visualization of biliary and pancreatic ducts. This study aims to evaluate the morphological features of major abnormalities and the role of biliary MRI in the etiological diagnosis of cholestatic icteruses. This is a retrospective study of 17 patients conducted in the Imaging Unit of the University Hospital of Fann and of the Principal hospital of Dakar over a period of 4 years and six months (January 2008 at July 2012)...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27783368/laparoscopic-revision-of-roux-en-y-gastric-bypass-to-biliopancreatic-diversion-with-duodenal-switch-technical-points
#10
Maud Robert, Arnaud Pasquer
No abstract text is available yet for this article.
October 25, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27765899/laparoscopy-in-duodenal-switch-safe-and-halves-length-of-stay-in-a-nationwide-cohort-from-the-scandinavian-obesity-registry
#11
D Edholm, S Axer, J Hedberg, M Sundbom
BACKGROUND AND AIMS: Unsatisfactory weight loss after gastric bypass or sleeve gastrectomy in super-obese patients (body mass index > 50) is a growing concern. Biliopancreatic diversion with duodenal switch results in greater weight loss, but is technically challenging to perform, especially as a laparoscopic procedure (Lap-DS). The aim of this study was to compare perioperative outcomes of Lap-DS and the corresponding open procedure (O-DS) in Sweden. MATERIAL AND METHODS: The data source was a nationwide cohort from the Scandinavian Obesity Surgery Registry and 317 biliopancreatic diversion with duodenal switch patients (mean body mass index = 56...
October 7, 2016: Scandinavian Journal of Surgery: SJS
https://www.readbyqxmd.com/read/27761722/robotic-assisted-laparoscopic-biliopancreatic-diversion-vertical-sleeve-gastrectomy-with-traditional-roux-en-y-duodenal-switch
#12
Muhammad A Jawad, Lars Nelson, Rena C Moon, Andre F Teixeira
BACKGROUND: Although effective, duodenal switch can be a complicated and time-consuming operation for surgeons. PURPOSE: The purpose of this article is to present our technique of biliopancreatic diversion and vertical sleeve gastrectomy, creating a 150-cm common channel and a 100-cm alimentary limb. MATERIAL AND METHODS: A robot-assisted technique was utilized in creating a biliopancreatic diversion and vertical sleeve gastrectomy. RESULTS: Laparoscopy was used for marking stitches and then the robot was docked...
October 19, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27752806/initial-approach-to-childhood-obesity-in-spain-a-multisociety-expert-panel-assessment
#13
Ramon Vilallonga, José Manuel Moreno Villares, Diego Yeste Fernández, Raquel Sánchez Santos, Felipe Casanueva Freijo, Francisco Santolaya Ochando, Nuria Leal Hernando, Albert Lecube Torelló, Luis Antonio Castaño González, Albert Feliu, Gontrand Lopez-Nava, Dolores Frutos, Antonio J Torres Garcia, Juan Carlos Ruiz de Adana
PURPOSE: In recent years, the incidence of childhood obesity in Europe, and Spain in particular, has increased dramatically. Bariatric surgery could play a major role in treating of adolescents with severe obesity. However, no specific guidelines for bariatric surgery currently exist in Spain. METHODS: The Board of the Spanish Society for Obesity Surgery and Metabolic Diseases (SECO) proposed a study of childhood obesity by using the Delphi method. This prospective study involved 60 experts from nine national societies...
October 17, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27744582/biliopancreatic-diversion-decreases-postprandial-apolipoprotein-a-iv-levels-in-mildly-obese-individuals-with-type-2-diabetes-mellitus-a-prospective-study
#14
Everton Cazzo, José Carlos Pareja, Bruno Geloneze, Elinton Adami Chaim, Maria Rita Lazzarini Barreto, Daniéla Oliveira Magro
BACKGROUND: Bariatric surgery usually leads to improvement on the general lipid profile, but its role in the levels of apolipoprotein A-IV (Apo-AIV) is not completely understood. Apo-AIV is a gut-released lipoprotein which is enrolled in satiety regulation and presents anti-inflammatory, anti-atherogenic, and anti-oxidative properties. The objective of this study was to determine the influence of biliopancreatic diversion (BPD) in the levels of Apo-AIV. METHODS: This is a prospective exploratory study which evaluated eight obese individuals with type 2 diabetes mellitus (T2DM) who underwent BPD (Scopinaro operation) and were followed-up for 12 months...
October 15, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27729733/review-of-endoscopic-radiofrequency-in-biliopancreatic-tumours-with-emphasis-on-clinical-benefits-controversies-and-safety
#15
REVIEW
María-Victoria Alvarez-Sánchez, Bertrand Napoléon
Most pancreatic cancers and extrahepatic cholangiocarcinomas are unresectable at the time of diagnosis, and even in case of a resectable cancer, for elderly or patients with coexistent comorbidities, surgery is not an option. Current treatment alternatives in these scenarios are very limited. Biliary stenting with self-expanding metal stents (SEMS) is the mainstay palliative treatment of biliary obstruction due to unresectable pancreatic cancer or cholangiocarcinoma. Nevertheless, more than 50% of SEMS become occluded after 6 mo due to tumour over- and ingrowth, leading to hospital readmissions and reinterventions that significantly impair quality of life...
October 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27720223/bariatric-surgery-and-intellectual-disability-furthering-evidence-based-practice
#16
REVIEW
Emma Gibbons, Amanda Faith Casey, Keith Z Brewster
BACKGROUND: Rates of morbid obesity are higher for individuals with intellectual disability (ID). Individuals with ID may find nutritional guidelines difficult to follow and many face personal and environmental barriers for physical activity. Bariatric surgery may reduce obesity related health comorbidities while promoting sustained weight loss in diverse populations. Yet no study has reviewed the feasibility of conducting bariatric surgery on individuals with ID. OBJECTIVES: To conduct a scoping review of literature on bariatric procedures performed on individuals with ID...
January 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/27704339/conversion-of-vertical-sleeve-gastrectomy-to-a-functional-single-anastomosis-gastric-bypass-technique-and-preliminary-results-using-a-non-adjustable-ring-instead-of-stapled-division
#17
Francesco Greco
BACKGROUND: Recent data show that some patients will have insufficient weight loss or experience weight regain after sleeve gastrectomy. Dilation of the sleeve over time or use of an inadequate technique may contribute to relapse of morbid obesity. Repeat sleeve gastrectomy is the most obvious option but requires stapling of scarred tissue, has a higher risk of leakage, and is prone to re-enlargement with time. We herein describe a simple and innovative technique with which to revise vertical sleeve gastrectomy (VSG) into functional single-anastomosis gastric bypass (f-SAGB)...
October 5, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27686233/the-impact-of-biliopancreatic-diversion-with-duodenal-switch-bpd-ds-over-9%C3%A2-years
#18
Gladys W Strain, Mehyar H Torghabeh, Michel Gagner, Faith Ebel, Gregory F Dakin, Jonathan S Abelson, Daniel Connolly, Alfons Pomp
BACKGROUND: There is limited information on the multiple long-term effects of the biliopancreatic diversion with duodenal switch (BPD/DS). METHODS: Patients who consented to a BPD/DS from 1999 to 2010 were evaluated for weight change, complications, comorbidity resolution, body composition, quality of life, and depressive symptoms during visits at 1, 3,5, 7, and 9 years. Descriptive statistics, analysis of variance, and pair-wise comparisons were calculated for each of the five follow-up cohorts vs...
September 29, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27683784/sadi-s-with-right-gastric-artery-ligation-technical-systematization-and-early-results
#19
Jordi Pujol Gebelli, Amador Garcia Ruiz de Gordejuela, Almino Cardoso Ramos, Mario Nora, Ana Marta Pereira, Josemberg Marins Campos, Manoela Galvão Ramos, Eduardo Lemos de Souza Bastos, João Batista Marchesini
Background: Bariatric surgery is performed all over the world with close to 500.000 procedures per year. The most performed techniques are Roux-en-Y gastric bypass and sleeve gastrectomy. Despite this data, the most effective procedure, biliopancreatic diversion with or without duodenal switch, represents only no more than 1.5% of the procedures. Technical complexity, morbidity, mortality, and severe nutritional adverse effects related to the procedure are the main fears that prevent most universal acceptance...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27683783/safety-and-effectiveness-of-single-anastomosis-duodenal-switch-procedure-preliminary-result-from-a-single-institution
#20
Lars Nelson, Rena C Moon, Andre F Teixeira, Manoel Galvão, Almino Ramos, Muhammad A Jawad
Background: Single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) was introduced into bariatric surgery by Sanchez-Pernaute et al. as an advancement of the biliopancreatic diversion with duodenal switch. Aim: To evaluate the SADI-S procedure with regard to weight loss, comorbidity resolution, and complication rate in the super obese population. Methods: A retrospective chart review was performed on initial 72 patients who underwent laparoscopic or robot-assisted laparoscopic SADI-S between December 17th, 2013 and July 29th, 2015...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
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