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Septic arthritis

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https://www.readbyqxmd.com/read/28809954/the-burden-of-septic-arthritis-on-the-u-s-inpatient-care-a-national-study
#1
Jasvinder A Singh, Shaohua Yu
OBJECTIVE: To assess the health care burden of septic arthritis in the U.S. and examine the associated factors. METHODS: We used the U.S. Nationwide Emergency Department Sample (NEDS) data of patients hospitalized with septic arthritis as the primary diagnosis from 2009-12 to assess time-trends. Multivariable-adjusted models assessed demographics, comorbidity and hospital characteristics as potential predictors of duration of hospitalization, total hospital (inpatient and ED) charges and discharge to home...
2017: PloS One
https://www.readbyqxmd.com/read/28803865/ureaplasma-urealyticum-necrotizing-soft-tissue-infection
#2
Ian Gassiep, Letitia Gore, Joanne L Dale, E Geoffrey Playford
Ureaplasma urealyticum is a urogenital commensal and often associated with localised infection. With the advent of monoclonal immunosuppressive therapy and improved diagnostic methods, reports of non-urogenital infections are accumulating. We report a rare case of U. urealyticum necrotizing soft tissue infection and left hip septic arthritis in a hypogammaglobulinaemic patient. Consideration of this organism as an etiological agent, and potential early use of nucleic-acid diagnostic investigation with empiric therapy including activity against Ureaplasma in this patient population may be warranted...
August 10, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28802679/impact-of-cell-wall-peptidoglycan-o-acetylation-on-the-pathogenesis-of-staphylococcus-aureus-in-septic-arthritis
#3
Gaurav Baranwal, Majd Mohammad, Anders Jarneborn, Bommana Raghunath Reddy, Archana Golla, Sumana Chakravarty, Lalitha Biswas, Friedrich Götz, Sahadev Shankarappa, Tao Jin, Raja Biswas
Staphylococcus aureus (S. aureus) is one of the most common pathogen causing septic arthritis. To colonize the joints and establish septic arthritis this bacterium needs to resist the host innate immune responses. Lysozyme secreted by neutrophils and macrophages is an important defense protein present in the joint synovial fluids. S. aureus is known to be resistant to lysozyme due to its peptidoglycan modification by O-acetylation of N-acetyl muramic acid. In this study we have investigated the role of O-acetylated peptidoglycan in septic arthritis...
August 7, 2017: International Journal of Medical Microbiology: IJMM
https://www.readbyqxmd.com/read/28793879/septic-arthritis-significantly-increased-the-long-term-mortality-in-geriatric-patients
#4
Chia-Jung Wu, Chien-Cheng Huang, Shih-Feng Weng, Ping-Jen Chen, Chien-Chin Hsu, Jhi-Joung Wang, How-Ran Guo, Hung-Jung Lin
BACKGROUND: The elderly are predisposed to septic arthritis (SA) because of the aging nature and increasing comorbidities. SA may in turn increase the long-term mortality in the geriatric patients; however, it remains unclear. We conducted this prospective nationwide population-based cohort study to clarify this issue. METHODS: Using Taiwan National Health Insurance Research Database (NHIRD), we identified 1667 geriatric participants (≥ 65 years) with SA and 16,670 geriatric participants without SA matched at a ratio of 1:10 by age, sex, and index date between 1999 and 2010...
August 9, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28791147/two-types-of-bone-necrosis-in-the-middle-triassic-pistosaurus-longaevus-bones-the-results-of-integrated-studies
#5
Dawid Surmik, Bruce M Rothschild, Mateusz Dulski, Katarzyna Janiszewska
Avascular necrosis, diagnosed on the basis of either a specific pathological modification of the articular surfaces of bone or its radiologic appearance in vertebral centra, has been recognized in many Mesozoic marine reptiles as well as in present-day marine mammals. Its presence in the zoological and paleontologic record is usually associated with decompression syndrome, a disease that affects secondarily aquatic vertebrates that could dive. Bone necrosis can also be caused by infectious processes, but it differs in appearance from decompression syndrome-associated aseptic necrosis...
July 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28775081/cervical-facet-joint-septic-arthritis-a-real-pain-in-the-neck
#6
Sahiba Sethi, Mathew Kurian Vithayathil
A 64-year-old man with a complex medical history and previous cervical arthritis with discectomy presents with a 2-day history of neck and lower back pain and shortness of breath, associated with left-sided muscle weakness. He has a fever with severe sepsis causing acute renal failure. MRI spine shows evidence of left cervical facet joint septic arthritis at C6-T1. He required 6 weeks of intravenous antibiotics and intensive support with ventilation and haemofiltration. After completion of antibiotics, he made a full recovery and regained neurological function before discharge...
August 3, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28774452/imaging-of-posttraumatic-arthritis-avascular-necrosis-septic-arthritis-complex-regional-pain-syndrome-and-cancer-mimicking-arthritis
#7
REVIEW
Andrey Rupasov, Usa Cain, Simone Montoya, Johan G Blickman
This article focuses on the imaging of 5 discrete entities with a common end result of disability: posttraumatic arthritis, a common form of secondary osteoarthritis that results from a prior insult to the joint; avascular necrosis, a disease of impaired osseous blood flow, leading to cellular death and subsequent osseous collapse; septic arthritis, an infectious process leading to destructive changes within the joint; complex regional pain syndrome, a chronic limb-confined painful condition arising after injury; and cases of cancer mimicking arthritis, in which the initial findings seem to represent arthritis, despite a more insidious cause...
September 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28771839/effect-of-arthroscopic-lavage-and-repeated-intra-articular-administrations-of-antibiotic-in-adult-horses-and-foals-with-septic-arthritis
#8
Matthieu Cousty, John David Stack, Cyril Tricaud, Florent David
OBJECTIVE: To evaluate the effect of arthroscopic lavage and repeated intra-articular administration of antibiotic in adult horses and foals with septic arthritis. STUDY DESIGN: Retrospective clinical study. ANIMALS: Adult horses and foals with septic arthritis (n = 62). METHODS: Age, sex, cause of septic synovitis, joint involved, hospitalization time, and outcome were recorded. Arthroscopic lavage was performed at day 0 (D 0)...
August 3, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28766274/pathogen-or-contaminant-distinguishing-true-infection-from-synovial-fluid-culture-contamination-in-patients-with-suspected-septic-arthritis
#9
Mary Louise Fowler, Clara Zhu, Kevin Byrne, Sarah B Lieber, Andrew Moore, Robert H Shmerling, Ziv Paz
BACKGROUND: Isolation of bacteria from synovial fluid (SF) is the gold standard for diagnosis of septic arthritis (SA). Contamination results in misdiagnosis and mismanagement. This study identifies clinical characteristics, microbiology, and outcomes of patients with contaminated SF and compares them with patients with true SA. METHODS: We conducted a retrospective study including all patients aged 18 and older admitted to a single, tertiary-care hospital between 1998 and 2015 with suspected SA and positive SF cultures...
August 1, 2017: Infection
https://www.readbyqxmd.com/read/28760709/antimicrobial-susceptibility-testing-of-kingella-kingae-with-broth-microdilution-and-disk-diffusion-using-eucast-recommended-media
#10
Erika Matuschek, Jenny Åhman, Gunnar Kahlmeter, Pablo Yagupsky
OBJECTIVES: Due to the increasing use of improved culture techniques and sensitive nucleic acid amplification assays, Kingella kingae was recognized as an important cause of invasive infections in young children, especially in septic arthritis, osteomyelitis, bacteremia and endocarditis. In 2016, EUCAST established clinical MIC breakpoints for K. kingae (published in EUCAST Clinical Breakpoint Tables v 7.0, 2017). The present study was carried out to produce MIC-zone diameter correlations for K...
July 28, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28754137/tuberculous-monoarthritis-of-the-wrist-in-a-patient-with-systemic-lupus-erythematosus-a-case-report
#11
W A N V Luke, M P M L Gunathilake, Duminda Munidasa, Dilshan Munidasa, S T De Silva
BACKGROUND: Unusual forms of tuberculosis are common among immune-suppressed patients, leading to challenges in diagnosis and management. We present a Sri Lankan patient with systemic lupus erythematosis, investigated for chronic wrist pain with low inflammatory markers and without systemic symptoms, who was subsequently diagnosed to have tuberculosis of the joint. CASE PRESENTATION: A 31-year-old woman with systemic lupus erythematosis in remission was evaluated for chronic left wrist pain without significant examination findings on presentation...
July 28, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28749922/outbreak-of-septic-arthritis-associated-with-intra-articular-injections-at-an-outpatient-practice-new-jersey-2017
#12
Kathleen Ross, Jason Mehr, Barbara Carothers, Rebecca Greeley, Isaac Benowitz, Lisa McHugh, David Henry, Lisa DiFedele, Eric Adler, Shereen Naqvi, Edward Lifshitz, Christina Tan, Barbara Montana
On March 6, 2017, the New Jersey Department of Health (NJDOH) was notified of three cases of septic arthritis in patients who had received intra-articular injections for osteoarthritic knee pain at a private outpatient practice. The practice voluntarily closed the next day. NJDOH, in conjunction with the local health department and the New Jersey Board of Medical Examiners, conducted an investigation and identified 41 cases of septic arthritis associated with intra-articular injections administered during 250 patient visits at the same practice, including 30 (73%) patients who required surgery...
July 28, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28746185/clinical-significance-of-delta-neutrophil-index-in-the-differential-diagnosis-between-septic-arthritis-and-acute-gout-attack-within-24-hours-after-hospitalization
#13
Jung Yoon Pyo, Dae Sik Kim, Seung Min Jung, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee
The most important differential diagnoses of acute monoarticular arthritis are septic arthritis and acute gout attack. Identifying infection is crucial in preventing the devastating outcome of septic arthritis. The delta neutrophil index (DNI) is a value that corresponds to the fraction of circulating immature granulocytes. As DNI reflects the burden of infection, we evaluated this index as a differentiating marker between septic arthritis and acute gout attack.The medical records of 149 patients with septic arthritis and 194 patients with acute gout attack were reviewed...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28745253/-gastrointestinal-symptoms-with-meningococcal-infection-emergence-of-neisseria-meningitidis-serogroup-w
#14
H F Wunderink, I N Vlasveld, M J Knol, A van der Ende, E H R van Essen, E J Kuijper
BACKGROUND: Meningococcal disease usually presents as meningitis and/or septicaemia, but can also present as pneumonia or arthritis. Since 2000, a worldwide increase in meningococcal disease is reported which is caused by a new virulent clone of serogroup W (MenW:cc11). This subtype is more likely to give an atypical clinical presentation and results in high mortality rates. CASE DESCRIPTION: A 68-year-old woman with polymyalgia rheumatica, managed with prednisone, developed an acute gastrointestinal syndrome of nausea, diarrhoea, vomiting, fever and chills...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28745007/better-arthritis-care-what-training-do-community-based-health-professionals-need-to-improve-their-care-of-people-with-arthritis-a-delphi-study
#15
J Erwin, K Edwards, A Woolf, S Whitcombe, S Kilty
OBJECTIVE: The aim of the present study was to identify the competencies that non-specialist community-based nurses and allied health professionals (AHPs) need to enable them to assess, care for and manage arthritis appropriately. METHODS: A Delphi survey with an expert panel of 43 rheumatology specialists and expert patients was used to identify the competencies needed by community-based nurses and AHPs to enable them to improve their care of people with arthritis...
July 26, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/28744778/acute-osteomyelitis-and-septic-arthritis-in-children-a%C3%A2-referral-hospital-based-study-in-iran
#16
Shima Mahmoudi, Babak Pourakbari, Katayoun Borhani, Mahmoud Khodabandeh, Sepideh Keshavarz Valian, Alireza Aziz-Ahari, Setareh Mamishi
Information concerning the epidemiology of acute osteomyelitis (OM), septic arthritis (SA) and concurrent OM and SA in children is limited. The aim of this study was to describe the epidemiology of OM, SA and concurrent OM and SA in children. During the 4 years of the study, 63,999 patients were admitted to the Children's Hospital, Tehran, Iran. We identified 111 patients with OM and/or SA during the 4‑year period. There were 72 cases of OM (11 cases per 10,000 children) and 90 cases of SA (11 cases per 10,000 children)...
July 25, 2017: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28739619/q-fever-prosthetic-joint-infection
#17
Scott Weisenberg, David Perlada, Thomas Peatman
Coxiella burnetii is the causative pathogen of the zoonotic infection Q fever. Most patients with Q fever experience a non-specific febrile illness, hepatitis or pneumonia. Q fever has recently been described as a cause of prosthetic joint septic arthritis, but remains very uncommonly reported. We present a case of Q fever prosthetic joint septic arthritis that has responded to a combination of two-stage surgical exchange and prolonged medical treatment with doxycycline and hydroxychloroquine.
July 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28733573/inadvertent-introduction-of-tissue-coring-into-joints-during-arthrocentesis-an-experimental-study
#18
Chi Xu, Haiwen Peng, Wei Chai, Xiang Li, Rui Li, Jiying Chen
BACKGROUND The aim of this study was to investigate whether needles introduce skin plugs into joints during arthrocentesis. MATERIAL AND METHODS In the first part of this study, the arthrocentesis site was scrubbed with a fluorescein sodium swab, and 90 needles were inserted through the joint tissue and collected for examination under a fluorescence microscope. In the second part of this study, the joints were injected using 720 needles of different gauges. Two different randomly assigned needle insertion techniques were used: needle insertion straight through the joint capsule (subgroup 1) or insertion of the needle into the subcutaneous tissue followed by flushing of the needle with 0...
July 22, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28725566/concomitant-crystal-induced-and-septic-arthritis
#19
Kohei Morinaga, Katsuo Yamanaka
No abstract text is available yet for this article.
2017: IDCases
https://www.readbyqxmd.com/read/28725560/haemophilus-influenzae-serotype-f-endocarditis-and-septic-arthritis
#20
Katerina Oikonomou, Basel Alhaddad, Kayla Kelly, Ravindra Rajmane, George Apergis
Haemophilus influenzae represents gram-negative coccobacilli which can cause endocarditis, meningitis, septicemia, pneumonia, septic arthritis. H.influenzae exists as encapsulated and unencapsulated (non-typeable) strains. Non-typeable H.influenzae are emerging pathogens especially in elderly population. We report a case of a 73 year old woman with bacteremia, endocarditis and septic arthritis due to H.influenzae serotype f. This case emphasizes the clinical features and the key elements of diagnosis and management of infections caused by non-typeable strains of H...
2017: IDCases
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