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tDCS and Pain

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https://www.readbyqxmd.com/read/29783893/the-effects-of-transcranial-direct-current-stimulation-tdcs-combined-with-group-exercise-treatment-in-subjects-with-chronic-low-back-pain-a-pilot-randomized-control-trial
#1
Sofia Straudi, Sergio Buja, Andrea Baroni, Claudia Pavarelli, Giulia Pranovi, Felipe Fregni, Nino Basaglia
OBJECTIVE: To test the efficacy of transcranial direct current stimulation (tDCS) in addition to group exercise on non-specific chronic low back pain. DESIGN: Double-blinded randomized control trial. SUBJECTS: Patients with non-specific chronic low back pain. METHODS: A total of 35 subjects were recruited and allocated to real- or sham-tDCS followed by a group exercise protocol. Each patient underwent five sessions of brain stimulation followed by 10 sessions of group exercise...
May 1, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29762886/automatic-m1-so-montage-headgear-for-transcranial-direct-current-stimulation-tdcs-suitable-for-home-and-high-throughput-in-clinic-applications
#2
Helena Knotkova, Alexa Riggs, Destiny Berisha, Helen Borges, Henry Bernstein, Vaishali Patel, Dennis Q Truong, Gozde Unal, Denis Arce, Abhishek Datta, Marom Bikson
OBJECTIVES: Non-invasive transcranial direct current stimulation (tDCS) over the motor cortex is broadly investigated to modulate functional outcomes such as motor function, sleep characteristics, or pain. The most common montages that use two large electrodes (25-35 cm2 ) placed over the area of motor cortex and contralateral supraorbital region (M1-SO montages) require precise measurements, usually using the 10-20 EEG system, which is cumbersome in clinics and not suitable for applications by patients at home...
May 15, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29747540/anodal-transcranial-direct-current-stimulation-to-enhance-rehabilitation-in-individuals-with-rotator-cuff-tendinopathy-a-triple-blind-randomized-control-trial
#3
Amélie Fournier Belley, Catherine Mercier, Maude Bastien, Guillaume Léonard, Nathaly Gaudreault, Jean-Sébastien Roy
Study Design Triple-blind parallel-group randomized control trial. Background Anodal transcranial direct current stimulation (a-tDCS) has been shown to enhance the effects of sensorimotor training in neurological populations. For treatment of rotator cuff (RC) tendinopathy, sensorimotor training leads to reduce pain and increase function. Addition of a-tDCS during a rehabilitation program centered on sensorimotor training could improve treatment outcome. Objective To compare a group receiving a rehabilitation program centered on sensorimotor training with a-tDCS to a group receiving the same rehabilitation program with sham a-tDCS in individuals with RC tendinopathy...
May 10, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29735015/the-causal-role-of-the-somatosensory-cortex-in-prosocial-behaviour
#4
Selene Gallo, Riccardo Paracampo, Laura Müller-Pinzler, Mario Carlo Severo, Laila Blömer, Carolina Fernandes-Henriques, Anna Henschel, Balint Kalista Lammes, Tatjana Maskaljunas, Judith Suttrup, Alessio Avenanti, Christian Keysers, Valeria Gazzola
Witnessing another person's suffering elicits vicarious brain activity in areas active when we ourselves are in pain. Whether this activity influences prosocial behavior remains debated. Here participants witnessed a confederate express pain via a reaction of the swatted hand or via a facial expression and could decide to reduce that pain by donating money. Participants donate more money on trials in which the confederate expressed more pain. EEG shows that activity of the SI hand region explains variance in donation; TMS shows that altering this activity interferes with the pain-donation coupling only when pain is expressed by the hand and HD-tDCS that altering SI activity also interferes with pain perception...
May 8, 2018: ELife
https://www.readbyqxmd.com/read/29704875/frequency-dependent-top-down-modulation-of-temporal-summation-by-anodal-transcranial-direct-current-stimulation-of-the-primary-motor-cortex-in-healthy-adults
#5
S Hughes, M Ali, P Sharma, N Insan, P H Strutton
BACKGROUND: Transcranial direct-current stimulation (tDCS) applied over the primary motor cortex has been shown to be effective in the treatment of a number of chronic pain conditions. However, there is a lack of understanding of the top-down analgesic mechanisms involved. METHOD: In this study, we investigated the effects of tDCS on the facilitation of subjective sensory and pain scores using a transcutaneous electrically-evoked measure of temporal summation. In this randomised, blinded, cross-over study healthy subjects received a single stimulus given at 0...
April 28, 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29652088/non-invasive-brain-stimulation-techniques-for-chronic-pain
#6
REVIEW
Neil E O'Connell, Louise Marston, Sally Spencer, Lorraine H DeSouza, Benedict M Wand
BACKGROUND: This is an updated version of the original Cochrane Review published in 2010, Issue 9, and last updated in 2014, Issue 4. Non-invasive brain stimulation techniques aim to induce an electrical stimulation of the brain in an attempt to reduce chronic pain by directly altering brain activity. They include repetitive transcranial magnetic stimulation (rTMS), cranial electrotherapy stimulation (CES), transcranial direct current stimulation (tDCS), transcranial random noise stimulation (tRNS) and reduced impedance non-invasive cortical electrostimulation (RINCE)...
April 13, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29600889/transcranial-direct-current-stimulation-in-the-modulation-of-neuropathic-pain-a-systematic-review
#7
Mírian Celly Medeiros Miranda David, Alexa Alves de Moraes, Maíra Lopes da Costa, Carlúcia Ithamar Fernandes Franco
Objective To investigate the neuromodulating effect of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Pain (NP). Method A systematic review of articles published in the past five years in MEDLINE, LILACS, Cochrane, Scopus, ScienceDirect, and PEDro. The search was carried out from February to May 2017 using the keywords: neuropathic pain, neuralgia, nerve pain, central pain, peripheral nerve pain, tDCS. The selected studies were full articles written in Portuguese, English, or Spanish with at least one control group, and no less than one pre- or post-intervention variable, with the exclusion of case studies or case series, animal model studies, and studies with combined therapy...
March 30, 2018: Neurological Research
https://www.readbyqxmd.com/read/29590000/feasibility-of-remotely-supervised-tdcs-in-a-person-with-neuropathic-pain-due-to-spinal-cord-injury
#8
Sandra Carvalho, Jorge Leite, Camila B Pinto, Leslie R Morse, Ross Zafonte, Felipe Fregni
No abstract text is available yet for this article.
March 28, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29577496/transcranial-direct-current-stimulation-for-upper-limb-neuropathic-pain-a-double-blind-randomized-controlled-trial
#9
Gwyn N Lewis, David A Rice, Michal Kluger, Peter J McNair
BACKGROUND: While promising, there are mixed findings for the efficacy of transcranial direct current stimulation (tDCS) for the management of chronic pain. The goal of the current study was to evaluate the effect of anodal tDCS on pain and function in people with upper limb neuropathic pain. METHODS: The study was a double-blinded, randomized controlled trial. Thirty participants were randomly allocated into active and sham tDCS groups. Baseline assessments of pain and function, as well as quantitative sensory testing (QST) to probe the function of the nociceptive system, were undertaken prior to participants receiving five days of active or sham anodal tDCS (1 mA) over the primary motor cortex...
March 25, 2018: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29573997/the-use-of-tdcs-as-a-therapeutic-option-for-tinnitus-a-systematic-review
#10
Amanda Dos Humildes Maia Santos, Afonso Paranhos Silva Santos, Henrique Souza Santos, Adriana Campos da Silva
INTRODUCTION: Due to the subjectivity of the tinnitus diagnosis and its diverse etiologies, establishing an effective treatment is complex. In this context, transcranial direct current stimulation, a noninvasive option, is available for most patients and has shown good results in the treatment of other symptoms such as chronic pain. OBJECTIVE: To evaluate the therapeutic response of tinnitus to transcranial direct current stimulation. METHODS: A systematic review of the literature was performed using the following descriptors: tinnitus, transcranial direct current stimulation and randomized clinical trial...
March 9, 2018: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29550374/transcranial-direct-current-stimulation-of-the-medial-prefrontal-cortex-modulates-the-propensity-to-help-in-costly-helping-behavior
#11
Chong Liao, Song Wu, Yue-Jia Luo, Qing Guan, Fang Cui
Social decision-making engages traditional decision-making processes (e.g. valuation), as well as social cognition processes (e.g. inferring the affective and mental states of another person). Neuroimaging and neuro-stimulation studies have suggested the involvement of the medial prefrontal cortex (mPFC) in a variety of social decision-making tasks. Yet no study has investigated the effect of the cortical excitability of mPFC in the decision-making of costly helping behavior. Here, we used tDCS to demonstrate the causal relationship between the cortical excitability of mPFC and costly helping decision-making...
March 14, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29547226/non-invasive-brain-stimulation-techniques-for-chronic-pain
#12
REVIEW
Neil E O'Connell, Louise Marston, Sally Spencer, Lorraine H DeSouza, Benedict M Wand
BACKGROUND: This is an updated version of the original Cochrane Review published in 2010, Issue 9, and last updated in 2014, Issue 4. Non-invasive brain stimulation techniques aim to induce an electrical stimulation of the brain in an attempt to reduce chronic pain by directly altering brain activity. They include repetitive transcranial magnetic stimulation (rTMS), cranial electrotherapy stimulation (CES), transcranial direct current stimulation (tDCS), transcranial random noise stimulation (tRNS) and reduced impedance non-invasive cortical electrostimulation (RINCE)...
March 16, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29528599/-transcranial-direct-current-stimulation-tdcs-psychiatric-use
#13
C Kornreich, P Cole, H Kajosch
Transcranial Direct Current Stimulation (tDCS) is a cheap, easy to use, and relatively safe noninvasive brain stimulation technique. It is increasingly used in several indications in psychiatry and neurology, mainly for depression, chronic pain and cognitive decline due to degenerative brain diseases. Its efficacy is probable in depression and must still be confirmed in numerous other indications. Lowcost devices for the general public are easy to find on the internet and are frequently used for non-therapeutic indications, like the improvement of video gamers' performances...
2018: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/29515438/effects-of-transcranial-direct-current-stimulation-block-remifentanil-induced-hyperalgesia-a-randomized-double-blind-clinical-trial
#14
Gilberto Braulio, Savio C Passos, Fabricio Leite, Andre Schwertner, Luciana C Stefani, Ana C S Palmer, Iraci L S Torres, Felipe Fregni, Wolnei Caumo
Background: Remifentanil-induced hyperalgesia (r-IH) involves an imbalance in the inhibitory and excitatory systems. As the transcranial Direct Current Stimulation (tDCS) modulates the thalamocortical synapses in a top-down manner, we hypothesized that the active (a)-t-DCS would be more effective than sham(s)-tDCS to prevent r-IH. We used an experimental paradigm to induce temporal summation of pain utilizing a repetitive cold test (rCOLDT) assessed by the Numerical Pain Score (NPS 0-10) and we evaluated the function of the descending pain modulatory system (DPMS) by the change on the NPS (0-10) during the conditioned pain modulation (CPM)-task (primary outcomes)...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29472134/disruption-of-cortical-synaptic-homeostasis-in-individuals-with-chronic-low-back-pain
#15
Tribikram Thapa, Thomas Graven-Nielsen, Lucinda S Chipchase, Siobhan M Schabrun
OBJECTIVE: Homeostatic plasticity mechanisms regulate synaptic plasticity in the human brain. Impaired homeostatic plasticity may contribute to maladaptive synaptic plasticity and symptom persistence in chronic musculoskeletal pain. METHODS: We examined homeostatic plasticity in fifty individuals with chronic low back pain (cLBP) and twenty-five pain-free controls. A single block (7-min) of anodal transcranial direct current stimulation ('single tDCS'), or two subsequent blocks (7-min and 5-min separated by 3-min rest; 'double tDCS'), were randomised across two experimental sessions to confirm an excitatory response to tDCS applied alone, and evaluate homeostatic plasticity, respectively...
May 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29450801/enhancement-of-pain-inhibition-by-working-memory-with-anodal-transcranial-direct-current-stimulation-of-the-left-dorsolateral-prefrontal-cortex
#16
Zoha Deldar, Nabi Rustamov, Suzie Bois, Isabelle Blanchette, Mathieu Piché
The aim of this study was to examine whether transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal cortex (DLPFC) enhances pain inhibition by improving working memory (WM). Forty healthy volunteers participated in two tDCS sessions. Pain was evoked by electrical stimulation at the ankle. Participants performed an n-back task (0-back and 2-back). The experimental protocol comprised five counterbalanced conditions (0-back, 2-back, pain, 0-back with pain and 2-back with pain) that were performed twice (pre-tDCS baseline and during tDCS)...
February 15, 2018: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/29274881/neurobiological-mechanisms-of-antiallodynic-effect-of-transcranial-direct-current-stimulation-tdcs-in-a-mice-model-of-neuropathic-pain
#17
Andressa Souza, Daniel F Martins, Liciane Fernandes Medeiros, Catharina Nucci-Martins, Thiago César Martins, Aline Siteneski, Wolnei Caumo, Adair Roberto Soares Dos Santos, Iraci L S Torres
BACKGROUND: Neuropathic pain is relatively common and occurs in approximately 6-8% of the population. It is associated with allodynia and hyperalgesia. Thus, non-pharmacological treatments, such as transcranial direct current stimulation (tDCS) may be useful for relieving pain. OBJECTIVES: This study aimed to investigate the antiallodynic effect of tDCS in a mice model of neuropathic pain, and the underlying neurotransmission systems that could drive these effects...
March 1, 2018: Brain Research
https://www.readbyqxmd.com/read/29234136/study-adherence-in-a-tdcs-longitudinal-clinical-trial-with-people-with-spinal-cord-injury
#18
Sandra Carvalho, Jorge Leite, Felipe Jones, Leslie R Morse, Ross Zafonte, Felipe Fregni
STUDY DESIGN: Secondary analysis of a clinical trial. OBJECTIVES: To analyze adherence to 1-year transcranial Direct Current Stimulation (tDCS) clinical trial in people with chronic pain due to spinal cord injury (SCI). We also explore the association between dropout and several baseline variables such as age, depression levels, pain severity, number of days with pain in the last 7 days, walking ability, sleep, work, relationship with others, and enjoyment with life...
December 13, 2017: Spinal Cord
https://www.readbyqxmd.com/read/29213529/therapeutic-effect-of-transcranial-direct-current-stimulation-on-neuropsychological-symptoms-of-an-elderly-patient-a-case-report
#19
Aline Iannone, Joaquim Brasil-Neto, Antonio Pedro Mello Cruz, Corina Satler, Nasser Allam
Although growing evidence points to the potential therapeutic effects of transcranial Direct Current Stimulation (tDCS), there is still no consensus on the most appropriate protocol to be used in specific neurological and neuropsychological symptoms. This case report evaluated the neuromodulatory therapeutic effects of two 15-day courses of tDCS on an elderly female patient, aged 78 years with mild neurocognitive disorder, chronic pain and depression-related symptoms. Results indicated an overall significant improvement of cognitive and executive functions, as well as reduction in both depression and chronic pain symptoms...
July 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29190741/preoperative-transcranial-direct-current-stimulation-exploration-of-a-novel-strategy-to-enhance-neuroplasticity-before-surgery-to-control-postoperative-pain-a-randomized-sham-controlled-study
#20
RANDOMIZED CONTROLLED TRIAL
Hugo Ribeiro, Ricardo Bertol Sesterhenn, Andressa de Souza, Ana Claudia de Souza, Monique Alves, Jessica Catarina Machado, Nathalia Bofill Burger, Iraci Lucena da Silva Torres, Luciana Cadore Stefani, Felipe Fregni, Wolnei Caumo
BACKGROUND: An imbalance in the excitatory/inhibitory systems in the pain networks may explain the persistent chronic pain after hallux valgus surgery. Thus, to contra-regulate this dysfunction, the use of transcranial direct current stimulation (tDCS) becomes attractive. OBJECTIVE: We tested the hypothesis that two preoperative active(a)-tDCS sessions compared with sham(s)-tDCS could improve the postoperative pain [as indexed by Visual Analogue Scale (VAS) at rest and during walking (primary outcomes)]...
2017: PloS One
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