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Osteoarticular infections

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https://www.readbyqxmd.com/read/28696851/us-evaluation-of-juvenile-idiopathic-arthritis-and-osteoarticular-infection
#1
Jie C Nguyen, Kenneth S Lee, Mahesh M Thapa, Humberto G Rosas
Juvenile idiopathic arthritis (JIA) and osteoarticular infection can cause nonspecific articular and periarticular complaints in children. Although contrast material-enhanced magnetic resonance imaging is the reference standard imaging modality, musculoskeletal ultrasonography (US) is emerging as an important adjunct imaging modality that can provide valuable information relatively quickly without use of radiation or the need for sedation. However, diagnostic accuracy requires a systemic approach, familiarity with various US techniques, and an understanding of maturation-related changes...
July 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28683356/scintigraphic-imaging-of-staphylococcus-aureus-infection-using-99m-tc-radiolabeled-aptamers
#2
Sara Roberta Dos Santos, Camila Maria de Sousa Lacerda, Iêda Mendes Ferreira, André Luís Branco de Barros, Simone Odília Fernandes, Valbert Nascimento Cardoso, Antero Silva Ribeiro de Andrade
Staphylococcus aureus is a specie of great medical importance associated with many infections as bacteremia and infective endocarditis as well as osteoarticular, skin and soft tissue, pleuropulmonary, and device related infections. Early identification of infectious foci is crucial for successful treatment. Scintigraphy could contribute to this purpose since specific radiotracers were available. Aptamers due to their high specificity have great potential for radiopharmaceuticals development. In the present study scintigraphic images of S...
June 28, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28661965/pyogenic-tenosynovitis-in-infants-a-case-series
#3
Céline Lironi, Christina Steiger, Céline Juchler, Vasiliki Spyropoulou, Eleftheria Samara, Dimitri Ceroni
Pyogenic tenosynovitis is an uncommon condition in children and there are few published case reports. We present a series of 11 cases who were treated in the Geneva's Children Hospital in the last 10 years. Kingella kingae was the main pathogen and the characteristics of infection (inflammatory indices, clinical findings and severity) are similar to other osteoarticular K kingae's infections in infants.
June 28, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28648390/clinical-and-microbiological-characteristics-of-unusual-manifestations-of-invasive-pneumococcal-disease
#4
Adrian Sousa, Maria Teresa Pérez-Rodríguez, Andrés Nodar, Lucía Martínez-Lamas, Francisco Jose Vasallo, Maximiliano Álvarez-Fernández, Manuel Crespo
INTRODUCTION: Invasive pneumococcal disease (IPD) typically presents as bacterial pneumonia, meningitis or primary bacteraemia. However, Streptococcus pneumoniae can produce infection at any level of the body (endocarditis, arthritis, spontaneous bacterial peritonitis, etc.), which is also known as unusual IPD (uIPD). There are very limited data available about the clinical and microbiological profile of these uncommon manifestations of pneumococcal disease. Our aim was to analyse clinical forms, microbiological profile, epidemiology and prognosis of a cohort of patients with unusual invasive pneumococcal disease (uIPD)...
June 22, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28607765/paediatric-bone-and-joint-infection
#5
REVIEW
Alexios D Iliadis, Manoj Ramachandran
Despite advances in understanding and management, paediatric osteoarticular infections continue to pose diagnostic difficulties for clinicians. Delays in diagnosis can lead to potentially devastating morbidity.No single investigation, including joint aspiration, is sufficiently reliable to diagnose conclusively paediatric bone and joint infection. Diagnosis should be based on a combination of clinical signs, imaging and laboratory investigations. Algorithms should supplement, and not replace, clinical decision making in all cases...
January 2017: EFORT open reviews
https://www.readbyqxmd.com/read/28599870/osteoarticular-infections-caused-by-streptococcus-pneumoniae-since-authorization-of-conjugate-vaccines
#6
María Arrizabalaga, Yolanda Borjas, María Peñaranda, Margarita Garau, Enrique Ruíz de Gopegui, Antoni Payeras
No abstract text is available yet for this article.
June 6, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28560175/miliary-tuberculosis-with-cerebral-liver-prostate-and-retroesophageal-involvement
#7
Raquel Goncalves, Pedro Lopes, Patrícia Mendes, João Trêpa, João Rua, Rosa Sá, Isabel Ramos, J Saraiva da Cunha
Miliary tuberculosis results from the lymphohematogenous spread of Mycobacterium tuberculosis and it is a rare form of this disease. The most affected places are the lymph nodes, pleura, and osteoarticular system, but any organ can be involved. Currently the disease is still endemic in developing countries by its close association with poor living conditions and malnutrition. Other comorbidities, particularly infection by human immunodeficiency virus (HIV), diabetes mellitus, smoking and alcoholism are of great importance in the epidemiology of this disease...
2017: IDCases
https://www.readbyqxmd.com/read/28529089/kinetics-of-biofilm-formation-by-staphylococcus-lugdunensis-strains-in-bone-and-joint-infections
#8
Xavier Argemi, Gilles Prévost, Philippe Riegel, Christian Provot, Stéphanie Badel-Berchoux, François Jehl, Elodie Olivares, Yves Hansmann
OBJECTIVE: To describe the clinical presentation and 1-year follow-up of patients with bone and joint infections (BJIs) caused by Staphylococcus lugdunensis and evaluate its biofilm-forming capacities. PATIENTS AND METHODS: Overall, 28 patients with BJIs from VISLISI clinical trials were included. We evaluated 1-year clinical follow-up and analyzed biofilm production kinetics of the 28 strains using the BioFilm Ring Test®. RESULTS: Of all patients, 12 had osteoarticular infections without material and 16 had prosthetic joint infections, of which 9 underwent a 1-stage revision procedure...
May 12, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28521913/a-6500-year-old-middle-neolithic-child-from-pollera-cave-liguria-italy-with-probable-multifocal-osteoarticular-tuberculosis
#9
Vitale S Sparacello, Charlotte A Roberts, Ammielle Kerudin, Romy Müller
Clear skeletal evidence of prehistoric tuberculosis (TB) is rare, especially in children. We describe and differentially diagnose the pathological changes displayed by a five-year-old child, Pollera 21 (PO21) dated to the Middle Neolithic of Liguria (Italy), or 5740±30 BP (Beta-409341; 6635-6453cal BP, 2σ, OxCal 4.2). PO21 shows a number of osteoarticular lesions, mainly of a lytic nature with very little bone proliferation: the vertebral column, the shoulder and pelvic girdles, and the ribcage are involved...
June 2017: International Journal of Paleopathology
https://www.readbyqxmd.com/read/28505016/the-contemporary-microbiology-of-osteoarticular-infections-in-young-children
#10
Rosa Alcobendas, Sara Murias, Agustín Remesal, Cristina Calvo
No abstract text is available yet for this article.
June 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28483045/fungal-musculoskeletal-infections
#11
REVIEW
Michael W Henry, Andy O Miller, Thomas J Walsh, Barry D Brause
Fungi are rare but important causes of osteoarticular infections, and can be caused by a wide array of yeasts and molds. Symptoms are often subacute and mimic those of other more common causes of osteoarticular infection, which can lead to substantial delays in treatment. A high index of suspicion is required to establish the diagnosis. The severity of infection depends on the inherent pathogenicity of the fungi, the immune status of the host, the anatomic location of the infection, and whether the infection involves a foreign body...
June 2017: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/28459811/the-clinical-features-of-590-patients-with-brucellosis-in-xinjiang-china-with-the-emphasis-on-the-treatment-of-complications
#12
Bin Jia, Fengbo Zhang, Ying Lu, Wenbao Zhang, Jun Li, Yuexin Zhang, Jianbing Ding
BACKGROUND: This study aims to analyze the clinical characteristics and treatment outcomes of 590 patients with brucellosis in Xinjiang, China. METHODOLOGY AND PRINCIPAL FINDINGS: The clinical characteristics, laboratory findings, complications and prognosis of 590 patients infected with brucellosis were retrospectively analyzed. These patients had a mean age of 44.24 ± 15.83 years with 60.5% having a history of close contacting with cattle and sheep. Of them, 53...
May 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28458733/what-is-the-optimal-reconstruction-option-after-the-resection-of-proximal-humeral-tumors-a-systematic-review
#13
REVIEW
Andrew Dubina, Brian Shiu, Mohit Gilotra, S Ashfaq Hasan, Daniel Lerman, Vincent Y Ng
PURPOSE: The proximal humerus is a common location for both primary and metastatic bone tumors. There are numerous reconstruction options after surgical resection. There is no consensus on the ideal method of reconstruction. METHODS: A systematic review was performed with a focus on the surgical reconstructive options for lesions involving the proximal humerus. RESULTS: A total of 50 articles and 1227 patients were included for analysis. Reoperation rates were autograft arthrodesis (11%), megaprosthesis (10%), RSA (17%), hemiarthroplasty (26%), and osteoarticular allograft (34%)...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/28450986/-major-sickle-cell-syndromes-and-infections-associated-with-this-condition-in-children-in-burkina-faso
#14
Sonia Douamba, Kisito Nagalo, Laure Tamini, Ismaël Traoré, Madibèlè Kam, Fla Kouéta, Diarra Yé
INTRODUCTION: This study aims to investigate infections in children with major sickle cell syndrome. METHODS: We conducted a monocentric descriptive retrospective hospital study in Ouagadougou, Burkina Faso, over a ten-year period. All children with major sickle cell syndrome (homozygous SS and double heterozygous SC, SDPunjab, Sβ thalassemic, SOArab and SE) hospitalized for microbiologically confirmed infections were enrolled in the study. RESULTS: One hundred and thirty-three patients met our inclusion criteria...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28430741/utility-of-8%C3%A2-h-and-time-decay-corrected-acquisition-scintigraphy-with-in-vitro-labeled-white-blood-cells-for-the-diagnosis-of-osteoarticular-infection
#15
Edel Noriega-Álvarez, Guillermo A Martínez Pimienta, Ana M Benítez Segura, María T Bajén Lázaro, Alba Rodríguez-Gasén, Julio Rodríguez-Rubio Corona, Jaime Mora-Salvadó
INTRODUCTION: Except in the spine, labeled white-blood cell scintigraphy (WBCS) with image acquisition up to 24 h is the nuclear medicine test of choice for diagnosing osteoarticular infection. However, distinguishing between inflammation and infection is a challenge. OBJECTIVES: The first aim of this study was to verify earlier research studies that used 4 and 24 h time decay-corrected acquisition (TDCA) to differentiate infection from inflammation. The second aim was to analyze whether 8 h acquisition (1-day protocol) yielded similar results as 20-24 h acquisition...
June 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28410697/multifocal-pure-tubercular-osteomyelitis-an-unusual-presentation-in-childhood
#16
Sananda Pati, Sangita De, Tarak Nath Ghosh, Mrinal Kanti Ghosh
Tuberculosis is a major health problem in the developing world. One-third of children infected with Mycobacterium tuberculosis have extra pulmonary involvement. Skeletal tuberculosis occurs in 1-6% of them with vertebra being the commonest site. Pure tubercular osteomyelitis without joint involvement occurs in only 2-3% cases of osteoarticular tuberculosis. Common sites are femur, tibia, and fibula. Disseminated skeletal involvement is very rare in children (7%) and calvarial osteomyelitis is even rarer (1%)...
April 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28385943/is-there-still-a-role-for-osteoarticular-allograft-reconstruction-in-musculoskeletal-tumour-surgery-a-long-term-follow-up-study-of-38-patients-and-systematic-review-of-the-literature
#17
REVIEW
M P A Bus, M A J van de Sande, A H M Taminiau, P D S Dijkstra
AIMS: To assess complications and failure mechanisms of osteoarticular allograft reconstructions for primary bone tumours. PATIENTS AND METHODS: We retrospectively evaluated 38 patients (28 men, 74%) who were treated at our institution with osteoarticular allograft reconstruction between 1989 and 2010. Median age was 19 years (interquartile range 14 to 32). Median follow-up was 19.5 years (95% confidence interval (CI) 13.0 to 26.1) when 26 patients (68%) were alive...
April 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28355767/-effects-of-reconstruction-with-unicondylar-osteoarticular-allografts-with-or-without-prosthesis-for-bone-tumors-around-knee-joint
#18
Y S Xue, J Fu, Z Guo, Z Wang, Y J Pei, L L Dang, H B Fan
Objective: To investigate the survival rate, function outcomes, and complications after using unicondylar osteoarticular allografts with or without prosthesis to reconstruct the knee joint for tumors located in distal femoral or proximal tibial uni-condyle. Methods: Twenty-two patients who underwent unicondylar osteoarticular allografts with or without prosthesis composite reconstructions from January 2007 to December 2015 in Department of Orthopaedic Surgery of Xi Jing Hospital, the Fourth Military Medical University were retrospectively reviewed...
April 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28322887/staphylococcus-aureus-bacteremia-in-patients-with-rheumatoid-arthritis-data-from-the-prospective-instinct-cohort
#19
Insa Joost, Achim Kaasch, Christine Pausch, Gabriele Peyerl-Hoffmann, Christian Schneider, Reinhard E Voll, Harald Seifert, Winfried V Kern, Siegbert Rieg
OBJECTIVES: Patients with rheumatoid arthritis (RA) are considered to be at increased risk of severe infections. We here describe the clinical characteristics, course and outcome of RA patients with Staphylococcus aureus bacteremia (SAB). METHODS: We conducted a post hoc analysis of data from a German bi-center prospective SAB cohort study (period 2006-2014). Patients were followed-up for one year. Primary and secondary outcomes were survival time and osteoarticular infection (OAI)...
March 18, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28317027/the-type-a-and-type-b-polysaccharide-capsules-predominate-in-an-international-collection-of-invasive-kingella-kingae-isolates
#20
Eric A Porsch, Kimberly F Starr, Pablo Yagupsky, Joseph W St Geme
Kingella kingae is an encapsulated Gram-negative bacterium and an important etiology of osteoarticular infections in young children. A recent study examining a diverse collection of carrier and invasive K. kingae isolates from Israel revealed four distinct polysaccharide capsule types. In this study, to obtain a global view of K. kingae capsule type diversity, we examined an international collection of isolates using a multiplex PCR approach. The collection contained all four previously identified capsule types and no new capsule types...
March 2017: MSphere
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