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Osteoarticular infections

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https://www.readbyqxmd.com/read/29773407/osteoarticular-infections-in-pediatric-patients-the-aetiological-importance-of-kingella-kingae
#1
Amadeu Gené Giralt, Guillermo Ludwig Sanz-Orrio, Carmen Muñoz-Almagro, Antoni Noguera-Julián
No abstract text is available yet for this article.
May 14, 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29759128/autoimmunity-mimics-infection-and-malignancy
#2
REVIEW
Jeffrey C Eickhoff, Angelique N Collamer
Musculoskeletal rheumatic syndromes are commonly encountered in the primary care setting. A plethora of commonly encountered and rare infectious agents can produce osteoarticular and soft tissue manifestations. Likewise, malignancies may manifest rheumatic symptoms via direct tumor invasion or paraneoplastic effects. Awareness of these diseases and their clinical risk factors should result in improved screening and earlier recognition and intervention, leading to improved long-term outcomes and overall patient care...
June 2018: Primary Care
https://www.readbyqxmd.com/read/29751119/bacteriological-relevance-of-linezolid-versus-vancomycin-in-postoperative-empirical-treatment-of-osteoarticular-infections-a-retrospective-single-center-study
#3
E Takoudju, P Bemer, S Touchais, N Asseray, S Corvec, L Khatchatourian, N Serandour, D Boutoille
BACKGROUND: Our center replaced vancomycin by linezolid in 2015 for the postoperative empirical treatment of osteoarticular infections (OAI). OBJECTIVES: This work aims to assess the bacteriological relevance of linezolid for orthopaedic postoperative probabilistic antibiotic therapy. METHODS: Analysis of an observational cohort of patients empirically treated by a combination of linezolid with piperacillin/tazobactam during the immediate postoperative stage for an OAI between July 1st 2015 and July 1st 2016, in a French reference center...
May 8, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29746950/candida-periprosthetic-joint-infection-a-rare-and-difficult-to-treat-infection
#4
Laura Escolà-Vergé, Dolors Rodríguez-Pardo, Jaime Lora-Tamayo, Laura Morata, Oscar Murillo, Helem Vilchez, Luisa Sorli, Laura Guío Carrión, José Mª Barbero, Julián Palomino-Nicás, Alberto Bahamonde, Alfredo Jover-Sáenz, Natividad Benito, Rosa Escudero, Marta Fernandez- Sampedro, Rafael Pérez Vidal, Lucía Gómez, Pablo S Corona, Benito Almirante, Javier Ariza, Carles Pigrau
BACKGROUND: Candida periprosthetic joint infection (CPJI) is a rare, difficult-to-treat disease. The purpose of this study was to evaluate the clinical characteristics and outcomes of CPJI treated with various surgical and antifungal strategies. METHODS: We conducted a multicenter retrospective study of all CPJI diagnosed between 2003 and 2015 in 16 Spanish hospitals. RESULTS: Forty-three patients included: median age, 75 years, and median Charlson Comorbidity Index score, 4...
May 7, 2018: Journal of Infection
https://www.readbyqxmd.com/read/29734665/pediatric-methicillin-resistant-staphylococcus-aureus-osteoarticular-infections
#5
REVIEW
Ashlesha Kaushik, Helen Kest
Osteoarticular infections (OSI) are a significant cause of hospitalizations and morbidity in young children. The pediatric patient with OSI presents unique challenges in diagnosis and management due to higher morbidity, effect on growth plate with associated long-lasting sequelae, and challenges in early identification and management. Methicillin-resistant Staphylococcus aureus (MRSA), first described in the 1960s, has evolved rapidly to emerge as a predominant cause of OSI in children, and therefore empiric treatment for OSI should include an antibiotic effective against MRSA...
May 4, 2018: Microorganisms
https://www.readbyqxmd.com/read/29705992/outpatients-with-acute-osteoarticular-infections-had-favourable-outcomes-when-they-received-just-oral-antibiotics-without-intravenous-antibiotics
#6
Rosa Alcobendas, Agustín Remesal, Sara Murias, Esmeralda Nuñez, Cristina Calvo
AIM: The traditional approach for acute paediatric osteoarticular infections (OAI) has comprised initial intravenous antibiotics followed by prompt oral antibiotics. We assessed how providing just oral antibiotics compared to the traditional two-step approach. METHODS: This prospective study was performed at the Hospital La Paz, Madrid, Spain, from September 2015 to September 2016. We compared 25 outpatients, with good general health and a mean age of 25 months who received just oral antibiotics, with 228 hospitalised children of a similar age who received intravenous and oral antibiotics from other hospitals in the Spanish Network of Osteoarticular Infections...
April 29, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29676872/-osteoarticular-tuberculosis-nosology-and-diagnostic-pitfalls
#7
C Kabore, M Poncin, B Hurtgen, F Moerman, M Moonen
Osteoarticular or skeletal tuberculosis is a clinical manifestation of extrapulmonary tuberculosis, occurring during the lympho-hematogenous spread of Mycobacterium tuberculosis from a pulmonary primary infection or reactivation of latent infection, years or even decades after the initial infection. Bone and joint tuberculosis is a rare disease with non-specific symptoms and radiological characteristics, often delaying diagnosis for more than a year after clinical onset. First-line hospital departments should develop a clinical suspicion when confronted with a subacute inflammatory bone or joint pathology in patients with underlying comorbidities, especially when coming from tuberculosis-endemic countries...
April 2018: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29672809/sapho-and-crmo-the-value-of-imaging
#8
Anne Grethe Jurik, Rikke Fuglsang Klicman, Paolo Simoni, Philip Robinson, James Teh
The syndromes synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) and chronic recurrent multifocal osteomyelitis (CRMO) constitute a group of chronic relapsing inflammatory osteoarticular disorders with frequently associated skin eruptions such as palmoplantar pustulosis and acne conglobata and rather characteristic imaging features in the form of osteitis and/or hyperostosis. CRMO predominantly occurs in children/adolescents and SAPHO in adults. Any skeletal site can be involved, and the imaging appearances vary, depending on the patient's age and the stage/age of the lesion...
April 2018: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/29665445/acute-kidney-injury-during-treatment-with-high-dose-cloxacillin-a-report-of-23-cases-and-literature-review
#9
Aurélie Lavergne, Cécile Vigneau, Elisabeth Polard, Louise Triquet, Nathalie Rioux-Leclercq, Pierre Tattevin, Léonard Golbin
BACKGROUND: International guidelines recommend high-dose cloxacillin for endocarditis or osteoarticular infections due to meticillin-susceptible staphylococci. However, data on the tolerability of these regimens are scarce. METHODS: We used the computerized registry of suspected drug-related adverse events in our institution. Cases of acute kidney injury (AKI), as defined by KDIGO, in patients receiving high-dose cloxacillin, were retrospectively reviewed. Data were collected from medical charts on a standardized questionnaire...
April 14, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29644292/serious-phlegmonous-lesion-of-the-hand-following-an-injury-by-vegetal-thorn-never-forget-pasteurella-multocida
#10
A Maleb, J Elmalki, O Bouayadi, Y Ben Lahlou, M Frikh, N Abdeljaouad, A Lemnouer, H Yacoubi, M Elouennass
Pasteurella multocida can cause serious infections after dog or cat bite. We report here a rare case of hand infection caused by P. multocida consecutive to an injury by a thorn of the prickly pear. It caused an amputation of the distal phalanx of the thumb in a trisomic patient. It is about a 27-year-old man who was admitted to the hospital with swelling and intense pain of the left hand. He reported a sting by a thorn of prickly pear 15 days before. The patient was admitted to proceed with operative irrigation and debridement...
February 2018: Trauma Case Reports
https://www.readbyqxmd.com/read/29621840/brucellosis
#11
Siobhan M Mor, Anke K Wiethoelter, Peter D Massey, Jennifer Robson, Kathryn Wilks, Penny Hutchinson
BACKGROUND: Brucellosis, also known as undulant, Mediterranean or Malta fever, is a systemic infection that causes fever, sweats, arthralgias and myalgias. A globally important disease, brucellosis is re-emerging in Australia in association with feral pig hunting activities. OBJECTIVE: This article aims to provide clinicians with an overview of brucellosis, covering epidemiology, clinical features, diagnosis, management and prevention. DISCUSSION: Brucellosis should be suspected in all patients with non-specific, flu-like illness who fall into one of the major risk groups (feral pig hunters, overseas travellers and migrants)...
March 2018: Australian journal of general practice
https://www.readbyqxmd.com/read/29570590/osteoarticular-infections-following-open-or-penetrating-trauma-in-children-in-the-post-community-acquired-methicillin-resistant-staphylococcus-aureus-era-the-impact-of-enterobacter-cloacae
#12
J Chase McNeil, Jesus G Vallejo, Kristina G Hulten, Sheldon L Kaplan
BACKGROUND: Most cases of pediatric osteoarticular infections (OAI) are hematogenous in nature and caused by Staphylococcus aureus. OAI in children can also occur through direct inoculation of microorganisms secondary to penetrating or open trauma. No studies in the US have evaluated the microbiology or outcomes of trauma-related OAI (TROAI) in children in the era of community-acquired MRSA (CA-MRSA). METHODS: Cases were identified from the inpatient infectious diseases consultation database at Texas Children's Hospital from Jan 2011-Dec 2016...
March 21, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29568531/-mycobacterium-kansasii-osteomyelitis-a-masquerading-disease
#13
Kiranmai Bhatt, Krishna Banavathi
Introduction: Non-tuberculous mycobacteria (NTM) are environmental bacteria capable of causing an opportunistic myriad of infections. Mycobacterium kansasii , one such NTM, is responsible for causing pulmonary disease in immunocompromised patients. Rare extrapulmonary manifestations such as lymphadenitis, osteoarticular manifestations, and skin and soft tissue infections are also observed. Case presentation: Here, we report an unusual case of sternoclavicular joint and elbow joint infection with M...
January 2018: JMM Case Reports
https://www.readbyqxmd.com/read/29557602/osteoarticular-infections-in-a-tertiary-care-children-s-hospital-epidemiology-and-clinical-characteristics-in-association-with-bacteremia
#14
Esmeralda Highton, M Guadalupe Pérez, Carola Cedillo Villamagua, María I Sormani, María S Mussini, Adela Isasmendi, José Pinheiró, Vanesa Reijtman, Moira Taicz, Alejandra Mastroianni, María E García, María T Rosanova
INTRODUCTION: Osteoarticular infections are an important cause of morbidity and may present with bacteremia. The epidemiology has changed in recent years. OBJECTIVES: To describe the epidemiological, clinical, and evolutionary characteristics of children with osteoarticular infections and compare patients with and without bacteremia. POPULATION AND METHODS: Retrospective cohort. Patients younger than 18 years admitted between January 1st, 2016 and December 31st, 2016 suspected of osteoarticular infections who had undergone an arthrocentesis and/or joint biopsy were included...
April 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29557598/community-acquired-methicillin-resistant-staphylococcus-aureus-infections-10-years-experience-in-a-children-s-hospital-in-the-city-of-rosario-argentina
#15
Gabriela Ensinck, Adriana Ernst, Gustavo Lazarte, Antonela Romagnoli, Yanina Sguassero, Nanci Míguez, Santiago López Papucci, Alicia Aletti, Ana Chiossone, Fernanda Pigozzi, Matías Pinotti, Ana Cantador
INTRODUCTION: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are a common reason for consultation in pediatrics. Most of them present as skin and soft tissue infections; however, invasive infections have increased during the last decade. OBJECTIVES: The main objective was to describe the clinical-epidemiological characteristics of CA-MRSA infections. The secondary objective was to compare prevalence, clinical presentation and antibiotic susceptibility with a pre-study period (1/2004-12/2007)...
April 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29542213/enterobacter-cloacae-osteoarticular-infection-without-risk-factors-case-report-and-review-of-the-literature
#16
Laila S Al Yazidi, Hina Hameed, David Isaacs, Matthias Axt, Alison Kesson
No abstract text is available yet for this article.
March 15, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29530845/association-of-vancomycin-mic-and-molecular-characteristics-with-clinical-outcomes-in-methicillin-susceptible-staphylococcus-aureus-acute-hematogenous-osteoarticular-infections-in-children
#17
Eric Y Kok, Jesus G Vallejo, Lauren M Sommer, Louie Rosas, Sheldon L Kaplan, Kristina G Hulten, J Chase McNeil
Strains of methicillin-resistant Staphylococcus aureus (MRSA), particularly those belonging to the USA300 pulsotype, have been well described to cause severe osteoarticular infections (OAIs). A vancomycin MIC of ≥1.5 μg/ml has been demonstrated to contribute to disease severity in adults with MRSA and even methicillin-susceptible S. aureus (MSSA) bacteremia. Little data exist describing the outcomes of MSSA OAIs in terms of molecular characteristics and vancomycin MIC. All patients/isolates were chosen from a surveillance study at Texas Children's Hospital (TCH)...
May 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29529639/what-are-the-complications-of-allograft-reconstructions-for-sarcoma-resection-in-children-younger-than-10-years-at-long-term-followup
#18
Luis A Aponte-Tinao, Jose I Albergo, Miguel A Ayerza, D Luis Muscolo, Federico Milano Ing, German L Farfalli
BACKGROUND: Preservation of limb function after resection of malignant bone tumors in skeletally immature children is challenging. Resection of bone sarcomas and reconstruction with an allograft in patients younger than 10 years old is one reconstructive alternative. However, long-term studies analyzing late complications and limb length discrepancy at skeletal maturity are scarce; this information would be important, because growth potential is altered in these patients owing to the loss of one physis during tumor resection...
March 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29514556/tuberculous-sacroiliitis-in-a-patient-with-systemic-lupus-erythematosus-a-case-report-and-literature-review
#19
E Calle, L A González, C H Muñoz, D Jaramillo, A Vanegas, G Vásquez
Systemic lupus erythematosus (SLE) patients are at higher risk of developing opportunistic infections such as tuberculosis (TB), especially extrapulmonary forms like osteoarticular TB, compared to the general population. However, tuberculous sacroiliitis has been scarcely reported in these patients. We present a 34-year-old woman with SLE who developed articular tuberculosis simultaneously affecting the right sacroiliac joint and the left knee. The patient was successfully treated with antituberculosis therapy for nine months...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29509649/presentation-and-investigation-of-pediatric-bone-and-joint-infections-in-the-pediatric-emergency-department
#20
Olugbenga Akinkugbe, Charles Stewart, Caoimhe McKenna
OBJECTIVE: The objective of this study was to evaluate the presenting features of bone and joint infections with a view to identify distinguishing trends that will be useful for pediatric emergency departments. METHODS: We performed a retrospective review of patient records over a 12-year period in the pediatric emergency department of a large regional pediatric teaching center serving a diverse population. RESULTS: There were 88 cases of osteoarticular infections during the study period...
March 5, 2018: Pediatric Emergency Care
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