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Osteoarticular infections

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https://www.readbyqxmd.com/read/28430741/utility-of-8%C3%A2-h-and-time-decay-corrected-acquisition-scintigraphy-with-in-vitro-labeled-white-blood-cells-for-the-diagnosis-of-osteoarticular-infection
#1
Noriega Álvarez Edel, Guillermo A Martínez Pimienta, Ana M Benítez Segura, María T Bajén Lázaro, Alba Rodrígez-Gasén, Julio Rodríguez-Rubio Corona, Mora Salvadó Jaime
INTRODUCTION: Except in the spine, labeled white-blood cell scintigraphy (WBCS) with image acquisition up to 24 h is the nuclear medicine test of choice for diagnosing osteoarticular infection. However, distinguishing between inflammation and infection is a challenge. OBJECTIVES: The first aim of this study was to verify earlier research studies that used 4 and 24 h time decay-corrected acquisition (TDCA) to differentiate infection from inflammation. The second aim was to analyze whether 8 h acquisition (1-day protocol) yielded similar results as 20-24 h acquisition...
April 26, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28410697/multifocal-pure-tubercular-osteomyelitis-an-unusual-presentation-in-childhood
#2
Sananda Pati, Sangita De, Tarak Nath Ghosh, Mrinal Kanti Ghosh
Tuberculosis is a major health problem in the developing world. One-third of children infected with Mycobacterium tuberculosis have extra pulmonary involvement. Skeletal tuberculosis occurs in 1-6% of them with vertebra being the commonest site. Pure tubercular osteomyelitis without joint involvement occurs in only 2-3% cases of osteoarticular tuberculosis. Common sites are femur, tibia, and fibula. Disseminated skeletal involvement is very rare in children (7%) and calvarial osteomyelitis is even rarer (1%)...
April 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28385943/is-there-still-a-role-for-osteoarticular-allograft-reconstruction-in-musculoskeletal-tumour-surgery-a-long-term-follow-up-study-of-38-patients-and-systematic-review-of-the-literature
#3
M P A Bus, M A J van de Sande, A H M Taminiau, P D S Dijkstra
AIMS: To assess complications and failure mechanisms of osteoarticular allograft reconstructions for primary bone tumours. PATIENTS AND METHODS: We retrospectively evaluated 38 patients (28 men, 74%) who were treated at our institution with osteoarticular allograft reconstruction between 1989 and 2010. Median age was 19 years (interquartile range 14 to 32). Median follow-up was 19.5 years (95% confidence interval (CI) 13.0 to 26.1) when 26 patients (68%) were alive...
April 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28355767/-effects-of-reconstruction-with-unicondylar-osteoarticular-allografts-with-or-without-prosthesis-for-bone-tumors-around-knee-joint
#4
Y S Xue, J Fu, Z Guo, Z Wang, Y J Pei, L L Dang, H B Fan
Objective: To investigate the survival rate, function outcomes, and complications after using unicondylar osteoarticular allografts with or without prosthesis to reconstruct the knee joint for tumors located in distal femoral or proximal tibial uni-condyle. Methods: Twenty-two patients who underwent unicondylar osteoarticular allografts with or without prosthesis composite reconstructions from January 2007 to December 2015 in Department of Orthopaedic Surgery of Xi Jing Hospital, the Fourth Military Medical University were retrospectively reviewed...
April 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28322887/staphylococcus-aureus-bacteremia-in-patients-with-rheumatoid-arthritis-data-from-the-prospective-instinct-cohort
#5
Insa Joost, Achim Kaasch, Christine Pausch, Gabriele Peyerl-Hoffmann, Christian Schneider, Reinhard E Voll, Harald Seifert, Winfried V Kern, Siegbert Rieg
OBJECTIVES: Patients with rheumatoid arthritis (RA) are considered to be at increased risk of severe infections. We here describe the clinical characteristics, course and outcome of RA patients with Staphylococcus aureus bacteremia (SAB). METHODS: We conducted a post hoc analysis of data from a German bi-center prospective SAB cohort study (period 2006-2014). Patients were followed-up for one year. Primary and secondary outcomes were survival time and osteoarticular infection (OAI)...
March 18, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28317027/the-type-a-and-type-b-polysaccharide-capsules-predominate-in-an-international-collection-of-invasive-kingella-kingae-isolates
#6
Eric A Porsch, Kimberly F Starr, Pablo Yagupsky, Joseph W St Geme
Kingella kingae is an encapsulated Gram-negative bacterium and an important etiology of osteoarticular infections in young children. A recent study examining a diverse collection of carrier and invasive K. kingae isolates from Israel revealed four distinct polysaccharide capsule types. In this study, to obtain a global view of K. kingae capsule type diversity, we examined an international collection of isolates using a multiplex PCR approach. The collection contained all four previously identified capsule types and no new capsule types...
March 2017: MSphere
https://www.readbyqxmd.com/read/28265268/brucella-and-osteoarticular-cell-activation-partners-in-crime
#7
REVIEW
Guillermo H Giambartolomei, Paula C Arriola Benitez, M Victoria Delpino
Osteoarticular brucellosis is the most common presentation of human active disease although its prevalence varies widely. The three most common forms of osteoarticular involvement are sacroiliitis, spondylitis, and peripheral arthritis. The molecular mechanisms implicated in bone damage have been recently elucidated. B. abortus induces bone damage through diverse mechanisms in which TNF-α and the receptor activator of nuclear factor kappa-B ligand (RANKL)-the natural modulator of bone homeostasis are involved...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28240756/assessment-and-therapeutic-choice-in-septic-arthritis-of-the-hip-in-an-intravenous-drug-abuser-case-report-at-14-years-follow-up-and-review-of-literature
#8
REVIEW
P Persiani, F M Ranaldi, O Mazza, A Calistri, M Bove, M Crostelli, C Villani
INTRODUCTION: Osteoarticular infections are found frequently in drug addicted individuals, representing one of the main reasons for their hospitalization. Through inoculation, the pathogenic agents can enter the individual's system directly through the skin or parenterally, transmitted, that is, through syringes and other objects used during such practice. In these particular conditions, or when the medical history is vague, a warranted suspicion and the execution of targeted research can help in the diagnosis of high-risk patients such as addicts...
January 2017: La Clinica Terapeutica
https://www.readbyqxmd.com/read/28239451/management-of-a-cluster-of-clostridium-difficile-infections-among-patients-with-osteoarticular-infections
#9
Jacqueline Färber, Sebastian Illiger, Fabian Berger, Barbara Gärtner, Lutz von Müller, Christoph H Lohmann, Katja Bauer, Christina Grabau, Stefanie Zibolka, Dirk Schlüter, Gernot Geginat
BACKGROUND: Here we describe a cluster of hospital-acquired Clostridium difficile infections (CDI) among 26 patients with osteoarticular infections. The aim of the study was to define the source of C. difficile and to evaluate the impact of general infection control measures and antibiotic stewardship on the incidence of CDI. METHODS: Epidemiological analysis included typing of C. difficile strains and analysis of possible patient to patient transmission. Infection control measures comprised strict isolation of CDI patients, additional hand washings, and intensified environmental cleaning with sporicidal disinfection...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28218329/dopamine-assisted-fixation-of-drug-loaded-polymeric-multilayers-to-osteoarticular-implants-for-tuberculosis-therapy
#10
Dan Li, Litao Li, Yunlong Ma, Yaping Zhuang, Dawei Li, Hong Shen, Xing Wang, Fei Yang, Yuanzheng Ma, Decheng Wu
Currently, the major issues in the treatment of osteoarticular tuberculosis (TB) after implant placement are low drug concentration at the infected focus and drug resistance resulting from the long-term chemotherapy. The application of drug-loaded polymeric multilayers on implantable devices offers a promising solution to the problems. Herein, a poly(ethylene glycol)-based hydrogel film embedded with isoniazid (INH)-loaded alginate microparticles was fixed to Ti implants via adhesive polydopamine, subsequently capped by poly(lactic-co-glycolic acid) membranes for the sustained and localized delivery of the anti-TB drug...
February 20, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28198193/association-between-dehydration-and-fever-during-the-first-week-of-life
#11
Ariane Boutin, Ana Carceller, Marie Pier Desjardins, Marisol Sanchez, Jocelyn Gravel
BACKGROUND: Trying to differentiate serious bacterial infection (SBI) from a self-limiting illness in febrile infants seen in the pediatric emergency department (PED) is a significant challenge. The aim of the study was to determine the prevalence of dehydration and its relationship to SBI in febrile full-term newborns under 1 week of age seen in a PED. METHODS: A retrospective observational study was carried out on all children younger than 8 days of age with fever who presented to a single, tertiary care, PED from January 2009 to April 2014...
February 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28141587/osteoarticular-and-soft-tissue-melioidosis-in-malaysia-clinical-characteristics-and-molecular-typing-of-the-causative-agent
#12
AbdelRahman Mohammad Zueter, Mahmoud Abumarzouq, Mohd Imran Yusof, Wan Faisham Wan Ismail, Azian Harun
INTRODUCTION: Melioidosis involving bone, joints, and soft tissue is rare and reported usually following dissemination of disease from infection elsewhere in the body; to a lesser degree, it can also be reported as the primary manifestation of melioidosis. METHODOLOGY: The orthopedic registry at Hospital University Sains Malaysia from 2008 until 2014 was retrospectively reviewed and was followed by molecular typing of Burkholderia pseudomallei. RESULTS: Out of 20 cases identified, 19 patients were confirmed to have osteoarticular and/or soft-tissue melioidosis...
January 30, 2017: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/28094193/factors-associated-with-infection-after-reconstructive-shoulder-surgery-for-proximal-humerus-tumors
#13
Sjoerd Th Meijer, Nuno R Paulino Pereira, Sjoerd P F Th Nota, Marco L Ferrone, Joseph H Schwab, Santiago A Lozano Calderón
BACKGROUND: The main reconstruction techniques for proximal humerus tumors include osteoarticular allografts (OAs), endoprostheses (EPs), or allograft prosthetic composites (APCs). A common complication is infection, and constructs involving the use of allografts are believed to be at a higher risk of infection. Literature comparing infection rates between different modalities of reconstruction is scarce and underpowered. The study purposes were (1) to determine and compare the prevalence of infection in patients who underwent reconstruction of the proximal humerus including OAs, EPs, and APCs; (2) to identify preoperative, perioperative, and postoperative predictors of infection that might be modifiable; and (3) to present our protocol of treatment in patients with superficial and deep infections...
January 13, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28053147/bone-and-joint-infections-caused-by-mucormycetes-a-challenging-osteoarticular-mycosis-of-the-twenty-first-century
#14
Saad J Taj-Aldeen, Maria N Gamaletsou, Blandine Rammaert, Nikolaos V Sipsas, Valerie Zeller, Emmanuel Roilides, Dimitrios P Kontoyiannis, Michael Henry, Vidmantas Petraitis, Brad Moriyama, David W Denning, Olivier Lortholary, Thomas J Walsh
Osteomyelitis and arthritis caused by mucormycetes are rare diseases that rank among the most challenging complications in orthopedic and trauma surgery. The aim of this work is to review the epidemiological, clinical, diagnostic, and therapeutic aspects of the osteoarticular mucormycosis with particular emphasis on high-risk patients. A systematic review of osteoarticular mucormycosis was performed using PUBMED and EMBASE databases from 1978 to 2014. Among 34 patients with median age 41 (0.5-73 years), 24 (71%) were males...
January 3, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28027279/the-influence-of-the-route-of-antibiotic-administration-methicillin-susceptibility-vancomycin-duration-and-serum-trough-concentration-on-outcomes-of-pediatric-staphylococcus-aureus-bacteremic-osteoarticular-infection
#15
J Chase McNeil, Sheldon L Kaplan, Jesus G Vallejo
BACKGROUND: Bacteremia is often one factor used in deciding the need for prolonged intravenous antimicrobial therapy in osteoarticular infections (OAI). We examined treatment practices and outcomes of bacteremic S. aureus osteoarticular infections (BOAI) evaluated at Texas Children's Hospital (TCH). METHODS: Cases of acute hematogenous OAI in children with positive blood cultures for S. aureus at TCH from 2011-2014 were reviewed. Orthopedic complications included chronic osteomyelitis, growth arrest, pathologic fracture, avascular necrosis and chronic dislocation...
December 23, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28002357/pediatric-sacroiliitis-clinical-and-microbiologic-differences-between-infants-and-children-adolescents
#16
Ambra Donzelli, Eleftheria Samara, Vassiliki Spyropoulou, Céline Juchler, Dimitri Ceroni
BACKGROUND: The aim of this study was to improve knowledge of pediatric pyogenic sacroiliitis (PSI) in the pediatric population based on a consecutive case series. METHOD: We conducted a single-center cross-sectional study on 16 patients admitted to the emergency department of our Hospital between January 1990 and December 2015 with a confirmed diagnosis of PSI. The patients were divided into 2 groups by age: infants (6 months - 4 years) and children-adolescents (4-16 years)...
December 19, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27956728/kingella-kingae-chest-mass-mimicking-a-tumor-in-an-11-month-old-baby
#17
Halima Dabaja-Younis, Imad Kassis, Anat Ilivitzki, Ran Steinberg, Yael Shachor-Meyouhas
Kingella kingae has been recognized as a common etiology of pediatric osteoarticular infections, especially among children younger than 5 years of age. In recent years, there have been reported cases of unusual manifestations. We report a rare case of a chest mass mimicking a tumor in an 11-month-old baby.
January 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27869401/yersiniosis-in-poland-in-2014
#18
Sylwia Kamińska, Małgorzata Sadkowska-Todys
OBJECTIVE: The aim of the study is to present the epidemiological situation of yersiniosis in Poland in 2014 and compare it with the situation in the previous years. MATERIAL AND METHODS: The evaluation was based on analysis of data from the annual bulletins “Infectious diseases and poisoning in Poland” for the period 2009-2014 (MP Czarkowski et al., National Institute of Hygiene and GIS – Chief Sanitary Inspectorate), interviews of individual yersiniosis cases, sent by the sanitary-epidemiological stations from the whole country and the data on deaths from the Department of Demographic Studies of the Central Statistical Office...
2016: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/27855056/-mixed-knee-arthrodesis-a-rescue-alternative-in-knee-periprosthetic-joint-infection
#19
Roberto Enrique López-Cervantes, Adrián Huematzin Rivera-Villa, Adrián Miguel-Pérez, René Morales-de Los Santos, Rubén Torres-González, José Manuel Pérez-Atanasio
BACKGROUND: Knee arthrodesis is a rescue procedure for patients with knee periprosthetic joint infection who are not candidates for a revision surgery. The actual methods present a high complication rate with only moderate efectivity. METHODS: We retrospectively analyzed 17 cases, of patients with knee periprosthetic joint infection and bone loss treated by intramedular expandable nail and monoplanar external fixator with a mínimum evolution of 1 year, evaluating the medical records and digitalized X-rays by 2 sub specialized doctors in osteoarticular rescue surgery...
2016: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/27844159/clinical-and-epidemiological-differences-between-implant-associated-and-implant-free-orthopaedic-infections
#20
Céline Cuérel, Sophie Abrassart, Julien Billières, Diego Andrey, Domizio Suva, Victor Dubois-Ferrière, Ilker Uçkay
PURPOSE: Although there have been many publications regarding the risk factors for implant-associated orthopaedic infections, none have investigated how clinical presentations and epidemiology may differ between infections with and without osteosynthetic material. METHODS: We pooled clinical data from several databases of adult patients with orthopaedic infections hospitalized at Geneva University Hospitals from January 2004 to December 2014. RESULTS: Among 2740 episodes of orthopaedic infections, 76% were implant-free osteoarticular or soft tissue infections...
February 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
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