keyword
MENU ▼
Read by QxMD icon Read
search

Dany

keyword
https://www.readbyqxmd.com/read/29244183/dna-damage-and-epigenetic-alteration-in-soybean-farmers-exposed-to-complex-mixture-of-pesticides
#1
Danieli Benedetti, Barbara Lopes Alderete, Claudia Telles de Souza, Johnny Ferraz Dias, Liana Niekraszewicz, Mónica Cappetta, Wilner Martínez-López, Juliana Da Silva
Exposure to pesticides can trigger genotoxic and mutagenic processes through different pathways. However, epidemiological studies are scarce, and further work is needed to find biomarkers sensitive to the health of exposed populations. Considering that there are few evaluations of soybean farmers, the aim of this study was to assess the effects of human exposure to complex mixtures of pesticides. The alkaline comet assay modified with restriction enzyme (hOGG1: human 8-oxoguanine DNA glycosylase) was used to detect oxidised guanine, and compared with the buccal micronucleus cytome assay, global methylation, haematological parameters, biochemical analyses (serum glutamic oxaloacetic transaminase, serum glutamic pyruvic transaminase, gamma-glutamyl-transferase and butyrylcholinesterase), and particle-induced X-ray emission (PIXE) for the analysis of inorganic elements...
December 13, 2017: Mutagenesis
https://www.readbyqxmd.com/read/29242945/degree-of-skin-barrier-disruption-affects-lipid-organization-in-regenerated-stratum-corneum
#2
Tineke Berkers, Dani Visscher, Gert S Gooris, Joke A Bouwstra
Previously, a skin barrier repair model was developed to examine the effect of formulations on the lipid properties of compromised skin. In this model, the lipid organization mimics that of several skin diseases with impaired skin barrier and less dense lateral lipid organization. In addition, parakeratosis was occasionally observed. The present study investigated whether the extent of initial barrier disruption affects lipid organization and parakeratosis in regenerated stratum corneum. After barrier disruption and stratum corneum regeneration the fraction of lipids adopting a less dense lateral organization gradually increased with increasing degree of barrier disruption...
December 15, 2017: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29237539/cdkn2a-deficiency-promotes-adipose-tissue-browning
#3
Nabil Rabhi, Sarah Anissa Hannou, Xavier Gromada, Elisabet Salas, Xi Yao, Frédérik Oger, Charlène Carney, Isabel C Lopez-Mejia, Emmanuelle Durand, Iandry Rabearivelo, Amélie Bonnefond, Emilie Caron, Lluis Fajas, Christian Dani, Philippe Froguel, Jean-Sébastien Annicotte
OBJECTIVES: Genome-wide association studies have reported that DNA polymorphisms at the CDKN2A locus modulate fasting glucose in human and contribute to type 2 diabetes (T2D) risk. Yet the causal relationship between this gene and defective energy homeostasis remains elusive. Here we sought to understand the contribution of Cdkn2a to metabolic homeostasis. METHODS: We first analyzed glucose and energy homeostasis from Cdkn2a-deficient mice subjected to normal or high fat diets...
December 1, 2017: Molecular Metabolism
https://www.readbyqxmd.com/read/29236088/dicationic-imidazolium-based-ionic-liquid-coatings-on-zirconia-surfaces-physico-chemical-and-biological-characterization
#4
Pavan P K Sandhu, Izabelle M Gindri, Danyal A Siddiqui, Danieli C Rodrigues
In the present work, dicationic imidazolium-based ionic liquids (ILs) were investigated as multi-functional coatings on a zirconia (ZrO₂) surface to prevent biofilm formation and enhance the wear performance of zirconia while maintaining the material's compatibility with host cells. ILs containing phenylalanine and methionine were synthesized and deposited on zirconia. Intermolecular interactions driving IL deposition on zirconia were studied using X-ray photoelectron spectroscopy (XPS). Anti-biofilm activity and cell compatibility were evaluated in vitro after one and seven days, and wear performance was tested using a pin-on-disk apparatus...
December 13, 2017: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/29233260/tooth-whitening-evaluation-of-blue-covarine-containing-toothpastes
#5
Danying Tao, Richard N Smith, Qiong Zhang, Jianing N Sun, Carole J Philpotts, Stephen R Ricketts, Mojgan Naeeni, Andrew Joiner
OBJECTIVES: To measure the tooth whitening effects delivered immediately after brushing with silica-based toothpastes containing blue covarine in vitro and in vivo. METHODS: Salivary pellicle coated human extracted teeth were brushed with either a slurry of a toothpaste containing blue covarine (BC), a formulation containing an increased level of blue covarine (BC+) or a negative control toothpaste containing no blue covarine. The colour of the specimens were measured in vitro using either a Minolta chromameter or a VITA Easyshade spectrophotometer, before and after brushing and changes in CIELAB values and tooth Whiteness Index (WIO) values calculated...
December 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/29232079/behavioral-design-teams-the-next-frontier-in-clinical-delivery-innovation
#6
Ted Robertson, Matthew Darling, Jennifer Leifer, Owen Footer, Dani Gordski
Issue: A deep understanding of human behavior is critical to designing effective health care delivery models, tools, and processes. Currently, however, few mechanisms exist to systematically apply insights about human behavior to improve health outcomes. Behavioral design teams (BDTs) are a successful model for applying behavioral insights within an organization. Already operational within government, this model can be adapted to function in a health care setting. Goal: To explore how BDTs could be applied to clinical care delivery and review models for integrating these teams within health care organizations...
November 1, 2017: Issue Brief of the Commonwealth Fund
https://www.readbyqxmd.com/read/29231248/slurp-1-is-mutated-in-mal-de-meleda-a-potential-molecular-signature-for-melanoma-and-a-putative-squamous-lineage-tumor-suppressor-gene
#7
Christina Bergqvist, Humam Kadara, Lamiaa Hamie, Georges Nemer, Remi Safi, Mirna Karouni, Nadine Marrouche, Ossama Abbas, Divina J Hasbani, Abdul G Kibbi, Dany Nassar, Yutaka Shimomura, Mazen Kurban
BACKGROUND: Mal de Meleda (MDM) is a rare inherited autosomal recessive genodermatosis characterized by palmoplantar keratoderma (PPK) with transgrediens and caused by mutations in the SLURP1 gene. Uncommonly, cutaneous tumors have been found at PPK sites in MDM patients. OBJECTIVE: To study a Middle Eastern family with MDM with both PPK and skin tumors. METHODS: We studied a Middle Eastern (Palestinian) family with clinical features of MDM and cutaneous tumors...
December 12, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/29223544/does-clinic-visit-education-within-a-multidisciplinary-center-improve-health-literacy-scores-in-caregivers-of-children-with-complex-colorectal-conditions
#8
Alexander J M Dingemans, Carlos A Reck, Alejandra Vilanova-Sanchez, Dani O Gonzalez, Alessandra C Gasior, Laura J Weaver, Renae Gagnon, Erin Hoover, Gabriel Sraha, Marc A Levitt, Richard J Wood
INTRODUCTION: Health literacy is low in an estimated one-third of the US population. Little is known about the health literacy of caregivers of children with colorectal conditions. The objective of this study was to investigate whether a timed health literacy intervention could improve health literacy in this population. METHODS: We used the BRIEF Health Literacy screening (BHLS) tool on caregivers of children who came to our colorectal clinic. Health literacy was categorized as inadequate, marginal, or adequate...
December 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29221426/enterogenous-cyst-of-the-small-bowel-mesentery-a-case-report-and-review-of-the-literature
#9
Donatas Danys, Raminta Martinaitytė, Jolanta Zacharic, Eligijus Poskus, Edvardas Zurauskas, Tomas Poskus, Kęstutis Strupas
INTRODUCTION: Enterogenous cysts are a very rare congenital abnormality that can be found anywhere within the gastrointestinal tract, most commonly in the small intestine. The incidence is approximately one in 4500-10,000 live births. Diagnosis can be suggested by ultrasound (US), computed tomography (CT) scans or magnetic resonance imaging (MRI) findings, although histological examination confirms the definitive diagnosis. PATIENTS: We present a case of enterogenous cyst in an adult female who underwent a resection of the tumour...
December 8, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29217959/periodontal-therapy-with-0-25-lemongrass-oil-mouthwash-in-reducing-risk-of-cardiovascular-diseases-a-3-arm-prospective-parallel-experimental-study
#10
Dany S Subha, Tangde Pradeep
Background: Periodontal disease is associated with cardiovascular diseases because of its role in host immune-inflammatory response. Serum lipids are the commonest risk factors between periodontal disease and cardiovascular diseases. Materials and Method: A double blinded randomised clinical trial was carried out among 45 subjects with generalised severe periodontitis. They were divided into 3-groups of 15 subjects each. Group A: 0.25% lemongrass oil mouthwash, Group B: 0...
September 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29215458/recurrence-of-renal-cell-cancer-after-renal-transplantation-in-a-multicenter-french-cohort
#11
Noëlle Cognard, Dany Anglicheau, Philippe Gatault, Sophie Girerd, Marie Essig, Bruno Hurault de Ligny, Yann Le Meur, Franck Le Roy, Cyril Garrouste, Antoine Thierry, Charlotte Colosio, Joseph Rivalan, Johnny Sayegh, Gabriel Choukroun, Bruno Moulin, Sophie Caillard
BACKGROUND: Renal cancer accounts for 3% of adult malignancies; renal cell carcinoma (RCC) represents 80% of all renal cancers, and is characterized by late recurrences. Recurrences after kidney transplantation are associated with a high mortality rate. We aimed to determine if recurrences are linked to tumor characteristics and to delays between diagnosis and transplantation. METHODS: We retrospectively analyzed data from French kidney-transplanted patients with medical histories of pre-transplant renal cancer, focusing on the most common histological subtypes: clear cell and papillary cancers...
December 5, 2017: Transplantation
https://www.readbyqxmd.com/read/29214721/surface-characterization-of-titanium-implant-healing-abutments-before-and-after-placement
#12
Sutton E Wheelis, Thomas G Wilson, Pilar Valderrama, Danieli C Rodrigues
BACKGROUND: Implant healing abutments (IHA) have a vital role in soft tissue healing after implant placement. Although there is thorough investigation on the implant surface, little is known about the effects potentially damaging oral conditions impose on healing abutments. PURPOSE: To characterize the surface of titanium healing abutments before and after clinical placement to understand the effects of the oral environment and time on the device surface. MATERIALS AND METHODS: Ten regular Straumann IHA were subjected to characterization pre and postplacement to elucidate the effects of the oral environment on device surfaces...
December 6, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/29209903/influence-of-a-co-culture-of-streptococcus-thermophilus-and-lactobacillus-casei-on-the-proteolysis-and-ace-inhibitory-activity-of-a-beverage-based-on-reconstituted-goat-whey-powder
#13
Áurea Marcela de Souza Pereira, Daniely Rayane Bezerra de Farias, Blenda Brito de Queiroz, Michelangela Suelleny de Caldas Nobre, Mônica Tejo Cavalcanti, Hévila Oliveira Salles, Karina Maria Olbrich Dos Santos, Ana Claudia Dantas de Medeiros, Eliane Rolim Florentino, Flávia Carolina Alonso Buriti
The potential for reusability of whey is of concern due to its substantial nutritional value and, second, in view of the need to reduce environmental impact. The use of goat whey powder in the production of a fermented dairy beverage using a Lactobacillus casei culture as adjunct shows a good prospect of a food product with hypotensive activity. This study investigated the microbial viability, proteolysis and angiotensin-converting enzyme (ACE) inhibitory activity of a fermented dairy beverage produced with goat whey powder and a probiotic culture of L...
December 5, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29207438/caterpillars-induce-jasmonates-in-flowers-and-alter-plant-responses-to-a-second-attacker
#14
Lucille T S Chrétien, Anja David, Eirini Daikou, Wilhelm Boland, Jonathan Gershenzon, David Giron, Marcel Dicke, Dani Lucas-Barbosa
In nature, herbivorous insects and plant pathogens are generally abundant when plants are flowering. Thus, plants face a diversity of attackers during their reproductive phase. Plant responses to one attacker can interfere with responses to a second attacker, and phytohormones that orchestrate plant reproduction are also involved in resistance to insect and pathogen attack. We quantified phytohormonal responses of flowering plants exposed to single or dual attack and studied resistance mechanisms of plants in the flowering stage...
December 5, 2017: New Phytologist
https://www.readbyqxmd.com/read/29206865/regulation-of-potassium-dependent-atpase-kdp-operon-of-deinococcus-radiodurans
#15
Pratiksha Dani, Aman Kumar Ujaoney, Shree Kumar Apte, Bhakti Basu
The genome of D. radiodurans harbors genes for structural and regulatory proteins of Kdp ATPase, in an operon pattern, on Mega plasmid 1. Organization of its two-component regulatory genes is unique. Here we demonstrate that both, the structural as well as regulatory components of the kdp operon of D. radiodurans are expressed quickly as the cells experience potassium limitation but are not expressed upon increase in osmolarity. The cognate DNA binding response regulator (RR) effects the expression of kdp operon during potassium deficiency through specific interaction with the kdp promoter...
2017: PloS One
https://www.readbyqxmd.com/read/29206350/isolated-v-lesion-in-kidney-transplant-recipients-characteristics-association-with-dsa-and-histological-follow-up
#16
Marion Rabant, Fanny Boullenger, Viviane Gnemmi, Gaëlle Pellé, François Glowacki, Alexandre Hertig, Isabelle Brocheriou, Caroline Suberbielle, Jean-Luc Taupin, Dany Anglicheau, Christophe Legendre, Jean-Paul Duong Van Huyen, David Buob
Isolated v-lesion (IvL) represents a rare and challenging situation in renal allograft biopsies because it is unknown whether IvL truly represents rejection, antibody- or T cell-mediated, or not. This multicentric retrospective study describes the clinicopathological features of IvL with an emphasis on the Donor Specific Antibodies (DSA) status, histological follow-up, and graft survival. Inclusion criteria were the presence of v-lesion with minimal interstitial (i≤1) and microvascular inflammation (g+ptc≤1)...
December 5, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/29202819/guidance-by-physicians-and-pharmacists-during-antidepressant-therapy-patients-needs-and-suggestions-for-improvement
#17
Mariёtte Nederlof, Daniёlle C Cath, Lennart J Stoker, Toine C G Egberts, Eibert R Heerdink
BACKGROUND: Guidance of patients treated with antidepressants is paramount for successful therapy. The aim was to assess patients' needs and suggestions for improvement of guidance by physicians and pharmacists during second generation antidepressant (SGA) therapy. METHODS: Five focus group discussions were held with a total of 34 patients using an SGA. The discussions were conducted flexibly and responsively using a semi-structured topic list. All focus group discussions were video-recorded and transcripts were analyzed using ATLAS...
December 4, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29202334/berberine-treatment-increases-akkermansia-in-the-gut-and-improves-high-fat-diet-induced-atherosclerosis-in-apoe-mice
#18
Lin Zhu, Danying Zhang, Hong Zhu, Jimin Zhu, Shuqiang Weng, Ling Dong, Taotao Liu, Yu Hu, Xizhong Shen
BACKGROUND AND AIMS: Gut microbiota plays a major role in metabolic disorders. Berberine is used to treat obesity, diabetes and atherosclerosis. The mechanism underlying the role of berberine in modulating metabolic disorders is not fully clear because berberine has poor oral bioavailability. Thus, we evaluated whether the antiatherosclerotic effect of berberine is related to alterations in gut microbial structure and if so, whether specific bacterial taxa contribute to the beneficial effects of berberine...
November 24, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29201995/protective-effect-of-antirheumatic-drugs-on-dementia-in-rheumatoid-arthritis-patients
#19
Andy Judge, Cesar Garriga, Nigel K Arden, Simon Lovestone, Dani Prieto-Alhambra, Cyrus Cooper, Christopher J Edwards
Introduction: Rheumatoid arthritis is a systemic inflammatory disease, and classical disease-modifying antirheumatic drugs (cDMARDs) have proven efficacy. It is unknown what impact cDMARDs might have on dementia as an outcome. Methods: Incident diagnoses of rheumatoid arthritis in persons over 18 years from 1995 to 2011 were identified from the UK Clinical Practice Research Datalink. There were 3876 cDMARD users and were propensity score matched to 1938 nonusers, on a wide range of confounders...
November 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29199012/choroidal-changes-after-suprachoroidal-injection-of-triamcinolone-in-eyes-with-macular-edema-secondary-to-retinal-vein-occlusion
#20
Alex S Willoughby, Vivian S Vuong, David Cunefare, Sina Farsiu, Glenn Noronha, Ronald P Danis, Glenn Yiu
PURPOSE: To evaluate choroidal and suprachoroidal changes following suprachoroidal injection of triamcinolone acetonide injectable suspension (CLS-TA), in eyes with macular edema due to retinal vein occlusion (RVO). DESIGN: Prospective cohort study within a randomized, controlled phase 2 clinical trial. METHODS: Enhanced-depth imaging optical coherence tomography (EDI-OCT) images were analyzed from 38 eyes of 38 treatment naïve patients with macular edema due to RVO, enrolled in the prospective Suprachoroidal Injection of Triamcinolone Acetonide with Intravitreal Aflibercept in Subjects with Macular Edema Due to Retinal Vein Occlusion (TANZANITE) study who received either a suprachoroidal injection of CLS-TA with an intravitreal injection of aflibercept (combination arm) or only an intravitreal injection of aflibercept (monotherapy arm) followed by monthly intravitreal aflibercept injections in both arms based on pro re nata (PRN) criteria...
November 30, 2017: American Journal of Ophthalmology
keyword
keyword
118306
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"