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JOURNAL ARTICLE
Miguel R Ramos, Danying Li, Matthew R Bennett, Unaysah Mogra, Douglas S Massey, Miles Hewstone
Both homophily and heterophily are observed in humans. Homophily reinforces homogeneous social networks, and heterophily creates new experiences and collaborations. However, at the extremes, high levels of homophily can cultivate prejudice toward out-groups, whereas high levels of heterophily can weaken in-group support. Using data from 24,726 adults ( M = 46 years; selected from 10,398 English neighborhoods) and the composition of their social networks based on age, ethnicity, income, and education, we tested the hypothesis that a middle ground between homophily and heterophily could be the most beneficial for individuals...
April 25, 2024: Psychological Science
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Iosif Lazaridis, Nick Patterson, David Anthony, Leonid Vyazov, Romain Fournier, Harald Ringbauer, Iñigo Olalde, Alexander A Khokhlov, Egor P Kitov, Natalia I Shishlina, Sorin C Ailincăi, Danila S Agapov, Sergey A Agapov, Elena Batieva, Baitanayev Bauyrzhan, Zsolt Bereczki, Alexandra Buzhilova, Piya Changmai, Andrey A Chizhevsky, Ion Ciobanu, Mihai Constantinescu, Marietta Csányi, János Dani, Peter K Dashkovskiy, Sándor Évinger, Anatoly Faifert, Pavel N Flegontov, Alin Frînculeasa, Mădălina N Frînculeasa, Tamás Hajdu, Tom Higham, Paweł Jarosz, Pavol Jelínek, Valeri I Khartanovich, Eduard N Kirginekov, Viktória Kiss, Alexandera Kitova, Alexeiy V Kiyashko, Jovan Koledin, Arkady Korolev, Pavel Kosintsev, Gabriella Kulcsár, Pavel Kuznetsov, Rabadan Magomedov, Mamedov Aslan Malikovich, Eszter Melis, Vyacheslav Moiseyev, Erika Molnár, Janet Monge, Octav Negrea, Nadezhda A Nikolaeva, Mario Novak, Maria Ochir-Goryaeva, György Pálfi, Sergiu Popovici, Marina P Rykun, Tatyana M Savenkova, Vladimir P Semibratov, Nikolai N Seregin, Alena Šefčáková, Mussayeva Raikhan Serikovna, Irina Shingiray, Vladimir N Shirokov, Angela Simalcsik, Kendra Sirak, Konstantin N Solodovnikov, Judit Tárnoki, Alexey A Tishkin, Viktov Trifonov, Sergey Vasilyev, Ali Akbari, Esther S Brielle, Kim Callan, Francesca Candilio, Olivia Cheronet, Elizabeth Curtis, Olga Flegontova, Lora Iliev, Aisling Kearns, Denise Keating, Ann Marie Lawson, Matthew Mah, Adam Micco, Megan Michel, Jonas Oppenheimer, Lijun Qiu, J Noah Workman, Fatma Zalzala, Anna Szécsényi-Nagy, Pier Francesco Palamara, Swapan Mallick, Nadin Rohland, Ron Pinhasi, David Reich
The Yamnaya archaeological complex appeared around 3300BCE across the steppes north of the Black and Caspian Seas, and by 3000BCE reached its maximal extent from Hungary in the west to Kazakhstan in the east. To localize the ancestral and geographical origins of the Yamnaya among the diverse Eneolithic people that preceded them, we studied ancient DNA data from 428 individuals of which 299 are reported for the first time, demonstrating three previously unknown Eneolithic genetic clines. First, a "Caucasus-Lower Volga" (CLV) Cline suffused with Caucasus hunter-gatherer (CHG) ancestry extended between a Caucasus Neolithic southern end in Neolithic Armenia, and a steppe northern end in Berezhnovka in the Lower Volga...
April 18, 2024: bioRxiv
#3
Yoed N Kenett, Evangelia G Chrysikou, Dani S Bassett, Sharon L Thompson-Schill
What are the neural dynamics that drive creative thinking? Recent studies have provided much insight into the neural mechanisms of creative thought. Specifically, the interaction between the executive control, default mode, and salience brain networks has been shown to be an important marker of individual differences in creative ability. However, how these different brain systems might be recruited dynamically during the two key components of the creative process- generation and evaluation of ideas-remains far from understood...
April 17, 2024: bioRxiv
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JOURNAL ARTICLE
Isa Mahendra, Ahmad Kurniawan, Muhamad Basit Febrian, Iim Halimah, Asep Rizaludin, Dani Gustaman Syarif
BACKGROUND: The use of appropriate animal models for cancer studies is a major challenge, particularly for investigators who lack the resources to maintain and use xenograft animals or genetically engineered mouse models (GEMM). In addition, several countries intending to incorporate these models must conduct importation procedures, posing an additional challenge. OBJECTIVE: This review aimed to explore the use of cell-derived allograft or syngeneic models under limited resources...
April 24, 2024: Curr Rev Clin Exp Pharmacol
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JOURNAL ARTICLE
Sophie Dani, Kathleen Schütz, Ezgi Dikici, Anne Bernhardt, Anja Lode
One of the biggest challenges in tissue engineering and regenerative medicine is to ensure oxygen supply of cells in the (temporary) absence of vasculature. With the vision to exploit photosynthetic oxygen production by microalgae, co-cultivated in close vicinity to oxygen-consuming mammalian cells, we are searching for culture conditions that are compatible for both sides. Herein, we investigated the impact of long-term illumination on mammalian cells which is essential to enable photosynthesis by microalgae: four different cell types-primary human fibroblasts, dental pulp stem cells, and osteoblasts as well as the murine beta-cell line INS-1-were continuously exposed to warm white light, red or blue light over seven days...
April 24, 2024: Scientific Reports
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JOURNAL ARTICLE
Johanna von Gerichten, Kyle D G Saunders, Anastasia Kontiza, Carla F Newman, George Mayson, Dany J V Beste, Eirini Velliou, Anthony D Whetton, Melanie J Bailey
We report the development and validation of an untargeted single-cell lipidomics method based on microflow chromatography coupled to a data-dependent mass spectrometry method for fragmentation-based identification of lipids. Given the absence of single-cell lipid standards, we show how the methodology should be optimized and validated using a dilute cell extract. The methodology is applied to dilute pancreatic cancer and macrophage cell extracts and standards to demonstrate the sensitivity requirements for confident assignment of lipids and classification of the cell type at the single-cell level...
April 23, 2024: Analytical Chemistry
#7
Julianus Aboyaman Uwuratuw, Nur Ramadhiany Lihawa, Muhammad Faruk, Muhammad Iwan Dani, Warsinggih
INTRODUCTION: One of the most prevalent primary liver cancer, particularly in Eastern Asia, is hepatocellular carcinoma (HCC), which has a poor prognosis. A rare condition known as situs inversus totalis (SIT) causes the abdominal and thoracic organs to be completely inverted. PRESENTATION OF CASE: A 51-year-old woman complained of a lump in the abdomen since 4 years ago, slowly enlarging to the suprapubic area, without pain. Laboratory findings showed an alpha-fetoprotein level was 13...
April 20, 2024: International Journal of Surgery Case Reports
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JOURNAL ARTICLE
Ruixia Zhao, Sinan Cheng, Xue Bai, Danying Zhang, Hongming Fang, Wanlin Che, Wenxuan Zhang, Yujuan Zhou, Wei Duan, Qiumin Liang, Li Xiao, Guochao Nie, Yingchun Hou
Hepatocellular carcinoma (HCC) is a digestive tract cancer with high mortality and poor prognosis, especially in China. Current chemotherapeutic drugs lead to poor prognosis, low efficacy, and high side effects due to weak targeting specificity and rapidly formed multidrug resistance (MDR). Based on the previous studies on the doxorubicin (DOX) formulation for cancer targeting therapy, we developed a novel DOX delivery formulation for the targeting chemotherapy of HCC and DOX resistant HCC. HCSP4 was previously screened and casein kinase 2α (CK2α) was predicted as its specific target on HCC cells in our lab...
April 2024: Biotechnology Journal
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JOURNAL ARTICLE
Munevver Dogramaci, Emily P Dobry, Evandro Fortini, Dipayan Sarkar, Dani Eshel, Michael A Campbell
Tuber dormancy is an important physiological trait that impacts postharvest storage and end use qualities of potatoes. Overall, dormancy regulation of potato tuber is a complex process driven by genetic as well as environmental factors. Elucidation of the molecular and physiological mechanisms that influence different dormancy stages of tuber has wider potato breeding and industry relevant implications. Therefore, the primary objective of this review is to present the current knowledge on the diversity in tuber dormancy traits among wild relatives of potatoes and discuss how genetic and epigenetic factors contribute to the tuber dormancy...
April 23, 2024: Journal of Experimental Botany
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JOURNAL ARTICLE
Janusz Springer, Michalina Pejska, Wojciech Homenda, Tomasz Zdrojewski, Ludmiła Daniłowicz-Szymanowicz, Dariusz Kozłowski
PURPOSE: Little is known about the effectiveness of pharmacological cardioversion (PCV) with antazoline in comparison to flecainide. The aim of this study was to compare the effectiveness of antazoline in restoring sinus rhythm (SR) versus amiodarone, flecainide and propafenone in a group of emergency department (ED) patients. MATERIALS/METHODS: This was a single-centre retrospective analysis of patient records from an ED in a large hospital in Poland. We analysed a total of 1878 patient records, divided based on the anti-arrhythmic drug (AAD) administered during PCV: antazoline (n=1080), antazoline + β-blocker (n=479), amiodarone (n=129), flecainide (n=102), propafenone (n=88)...
April 20, 2024: Advances in Medical Sciences
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JOURNAL ARTICLE
Michael P Castaldo, Elaine Neary, Adrianne R Bischoff, Maura H F Resende, Dany E Weisz, Amish Jain, Regan E Giesinger, Patrick J McNamara
No abstract text is available yet for this article.
August 2023: American Journal of Perinatology
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JOURNAL ARTICLE
Matthew A Adan, Christina Psaros, Grace Chamberlin, Dani Zionts, Surabhi Iyer, Laura Platt, Mairead Day Lopes, Susana Medeiros, Catherine O'Connor, Ingrid V Bassett, Kevin L Ard
Men who have sex with men (MSM) are disproportionately affected by HIV. Given that over 70% of MSM meet sexual partners via dating apps, such apps may be an effective platform for promoting HIV pre-exposure prophylaxis (PrEP) use. We aimed to describe preferences among MSM for PrEP advertisements displayed on dating apps. We conducted individual in-depth interviews with 16 MSM recruited from a mobile sexual health unit in Boston, Massachusetts. Two focus groups were also held: one with mobile unit staff ( N = 3) and one with mobile unit users ( N = 3)...
April 22, 2024: AIDS Care
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JOURNAL ARTICLE
Tuncay Sahutoglu, Ramazan Danis, Irem Pembegul, Ilyas Ozturk, Can Huzmeli, Murat Tugcu, Ebru Gok Oguz, Feyza Bora, Mahmud Islam, Yavuz Ayar, Zulfikar Yilmaz, Derya Basak Tanburoglu, Fatih Genc, Mehmet Emin Bindal, Serhan Tuglular, Rumeyza Kazancioglu
INTRODUCTION: Peritoneal dialysis (PD) remains understudied in disaster nephrology. This retrospective multicenter study explores the experiences of PD survivors following the February 6, 2023, Kahramanmaraş Earthquake. METHODS: Adult PD patients from 11 affected cities were analyzed to assess challenges faced during and postearthquake, alongside clinical outcomes. RESULTS: Among 101 participants (median age: 45 years, median PD duration: 24 months), 57 were female, with 79 on continuous ambulatory PD...
April 22, 2024: Therapeutic Apheresis and Dialysis
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JOURNAL ARTICLE
Dani Beck, Ann-Marie G de Lange, Tiril P Gurholt, Irene Voldsbekk, Ivan I Maximov, Sivaniya Subramaniapillai, Louise Schindler, Guy Hindley, Esten H Leonardsen, Zillur Rahman, Dennis van der Meer, Max Korbmacher, Jennifer Linge, Olof D Leinhard, Karl T Kalleberg, Andreas Engvig, Ida Sønderby, Ole A Andreassen, Lars T Westlye
Ageing is a heterogeneous multisystem process involving different rates of decline in physiological integrity across biological systems. The current study dissects the unique and common variance across body and brain health indicators and parses inter-individual heterogeneity in the multisystem ageing process. Using machine-learning regression models on the UK Biobank data set (N = 32,593, age range 44.6-82.3, mean age 64.1 years), we first estimated tissue-specific brain age for white and gray matter based on diffusion and T1-weighted magnetic resonance imaging (MRI) data, respectively...
April 15, 2024: Human Brain Mapping
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JOURNAL ARTICLE
Elena Laura-Arias, Miluska Villar-Guevara, Dany Yudet Millones-Liza
BACKGROUND: Building a path aimed at the wellbeing of workers in the education sector is the fundamental basis to encourage quality education. To fill the gap in knowledge and address this aspect by understanding the behavior of the study population, it was proposed as with the objective of determining if servant leadership, brand love and work ethic predict the general health in workers. METHODS: A non-probability sampling was applied for convenience. For this purpose, a sample of 509 workers from Peru was submitted to study, who completed a questionnaire consisting of: scale of servant leadership, work ethic, GHQ-12 and brand love...
2024: Frontiers in Psychology
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JOURNAL ARTICLE
Mohana Devi Subramaniam, Joon Suk Bae, Jiwon Son, Laurensia Danis Anggradita, Min-Kyu Kim, Min Yong Lee, Seokyoon Jang, Kwangok Choi, Justine C Lee, Seung Min Nam, Yongsung Hwang
Wound healing involves a complex and dynamic interplay among various cell types, cytokines, and growth factors. Macrophages and transforming growth factor-β1 (TGF-β1) play an essential role in different phases of wound healing. Cold atmospheric plasma has a wide range of applications in the treatment of chronic wounds. Hence, we aimed to investigate the safety and efficacy of a custom-made plasma device in a full-thickness skin defect mouse model. Here, we investigated the wound tissue on days 6 and 12 using histology, qPCR, and western blotting...
May 2024: Biomedical Engineering Letters
#17
JOURNAL ARTICLE
Mohil Garg, Patrick Creechan, Anita Sadeghpour, Dmitry Abramov, Sourbha S Dani, Sarju Ganatra, Sadeer G Al-Kindi, Erin D Michos, Arunima Misra, Anita Deswal, Nicolas L Palaskas, Salim S Virani, Vijay Nambi, Abdul Mannan Khan Minhas
No abstract text is available yet for this article.
April 19, 2024: American Journal of Cardiology
#18
JOURNAL ARTICLE
Daniely Oliveira Nunes Gama, Cristina Maria Meira de Melo, Tatiane Araújo Dos Santos, Handerson Silva-Santos, Neha Reddy, Johis Ortega, Maria Enoy Neves Gusmão
OBJECTIVES: Analyze and verify the association between working conditions and the occurrence of errors in nursing work. BACKGROUND: Many of the known errors in nursing are based on the structural failure of the complex health service system. Our study addresses the question "Is there an association between errors made by nursing workers and working conditions?" METHODS: The study was carried out through a cross-sectional exploratory analysis of 19 ethical-disciplinary processes focused on errors made by nursing workers...
April 2024: Applied Nursing Research: ANR
#19
JOURNAL ARTICLE
Thibaut Vaulet, Jasper Callemeyn, Baptiste Lamarthée, Asier Antoranz, Tim Debyser, Priyanka Koshy, Dany Anglicheau, Jill Colpaert, Wilfried Gwinner, Philip F Halloran, Dirk Kuypers, Claire Tinel, Amaryllis Van Craenenbroeck, Elisabet Van Loon, Pierre Marquet, Francesca Bosisio, Maarten Naesens
BACKGROUND: The link between the histology of kidney transplant rejection, especially Antibody-mediated rejection, T cell-mediated rejection and Mixed rejection, and the types of infiltrating immune cells is currently not well charted. Cost and technical complexity of single cell analysis hinder large scale studies of the relationship between cell infiltrate profiles and histological heterogeneity. METHODS: In this cross-sectional study, we assessed the composition of nine intragraft immune cell types by using a validated kidney transplant-specific signature matrix for deconvolution of bulk transcriptomics in three different kidney transplant biopsy datasets (N=403, N=224, N=282)...
April 19, 2024: Journal of the American Society of Nephrology: JASN
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JOURNAL ARTICLE
Rony Francisco Chilón-Troncos, Elizabeth Emperatriz García-Salirrosas, Manuel Escobar-Farfán, Dany Yudet Millones-Liza, Miluska Villar-Guevara
INTRODUCTION: The willingness to consume healthy foods has highlighted the growing importance of health, even more so when it comes to food choice, and predicting the willingness to consume foods of a healthy brand represents an action that leads to the practice of conscious eating habits, but what is behind this willingness? To answer this question and based on previous studies such as the theory of planned behavior and nutritional literacy, this study aimed to build a predictive model through an empirical study to examine the influence of nutritional literacy (NL) on attitude (ATT), subjective norm (SN) and perceived behavioral control (PBC), as well as to determine the influence of the three variables of the theory of planned behavior (TPB) on the willingness to consume healthy brand foods (WCHBF) in the Peruvian market...
2024: Frontiers in Nutrition
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