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https://www.readbyqxmd.com/read/28214180/a-successful-experience-of-the-iranian-blood-transfusion-organization-in-improving-accessibility-and-affordability-of-plasma-derived-medicine
#1
REVIEW
Azita Chegini, Seyed Ardeshir Torab, Ali Akbar Pourfatollah
Plasma is the liquid part of blood. It is estimated 21.6 million liters of plasma collect from Whole blood annually. From these plasma, 4.2 million liters transfuse, 8.1 million liters fractionate, 9.3 million liters waste. Nowadays, blood products and PDM (plasma derived medicine) consider as essential medicine in modern health care and transfusion medicine. Iranian blood transfusion organization as a non-profit organization was established in 1974 in order to centralize all blood transfusion activities from donor recruitment to distribution of blood components to hospitals...
January 4, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28214117/evaluating-carbon-fluxes-of-global-forest-ecosystems-by-using-an-individual-tree-based-model-forcchn
#2
Jianyong Ma, Herman H Shugart, Xiaodong Yan, Cougui Cao, Shuang Wu, Jing Fang
The carbon budget of forest ecosystems, an important component of the terrestrial carbon cycle, needs to be accurately quantified and predicted by ecological models. As a preamble to apply the model to estimate global carbon uptake by forest ecosystems, we used the CO2 flux measurements from 37 forest eddy-covariance sites to examine the individual tree-based FORCCHN model's performance globally. In these initial tests, the FORCCHN model simulated gross primary production (GPP), ecosystem respiration (ER) and net ecosystem production (NEP) with correlations of 0...
February 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28212975/budget-impact-analysis-of-prolonged-half-life-recombinant-fviii-therapy-for-hemophilia-in-the-united-states
#3
Suzanne McMullen, Brieana Buckley, Eric Hall, Jon Kendter, Karissa Johnston
BACKGROUND: Hemophilia A is a factor VIII deficiency, associated with spontaneous, recurrent bleeding episodes. This may lead to comorbidities such as arthropathy and joint replacement, which contribute to morbidity and increased health care expenditure. Recombinant factor VIII Fc fusion protein (rFVIIIFc), a prolonged half-life factor therapy, requires fewer infusions, resulting in reduced treatment burden. OBJECTIVE: Use a budget impact analysis to assess the potential economic impact of introducing rFVIIIFc to a formulary from the perspective of a private payer in the United States...
January 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28212950/incorporating-budget-impact-analysis-in-the-implementation-of-complex-interventions-a-case-of-an-integrated-intervention-for-multimorbid-patients-within-the-carewell-study
#4
Myriam Soto-Gordoa, Arantzazu Arrospide, Marisa Merino Hernández, Joana Mora Amengual, Ane Fullaondo Zabala, Igor Larrañaga, Esteban de Manuel, Javier Mar
OBJECTIVES: To develop a framework for the management of complex health care interventions within the Deming continuous improvement cycle and to test the framework in the case of an integrated intervention for multimorbid patients in the Basque Country within the CareWell project. METHODS: Statistical analysis alone, although necessary, may not always represent the practical significance of the intervention. Thus, to ascertain the true economic impact of the intervention, the statistical results can be integrated into the budget impact analysis...
January 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28211003/an-easy-to-build-low-budget-point-of-care-ultrasound-simulator-from-linux-to-a-web-based-solution
#5
Domagoj Damjanovic, Ulrich Goebel, Benedikt Fischer, Martin Huth, Hartmut Breger, Hartmut Buerkle, Axel Schmutz
BACKGROUND: Hands-on training in point-of-care ultrasound (POC-US) should ideally comprise bedside teaching, as well as simulated clinical scenarios. High-fidelity phantoms and portable ultrasound simulation systems are commercially available, however, at considerable costs. This limits their suitability for medical schools. A Linux-based software for Emergency Department Ultrasound Simulation (edus2TM) was developed by Kulyk and Olszynski in 2011. Its feasibility for POC-US education has been well-documented, and shows good acceptance...
December 2017: Critical Ultrasound Journal
https://www.readbyqxmd.com/read/28210864/pharmacy-benefit-management-companies-do-they-create-value-in-the-us-healthcare-system
#6
Alan Lyles
Pharmacy benefit management companies (PBMs) perform functions in the US market-based healthcare system that may be performed by public agencies or quasi-public institutions in other nations. By aggregating lives covered under their many individual contracts with payers, PBMs have formidable negotiating power. They influence pharmaceutical insurance coverage, design the terms of coverage in a plan's drug benefit, and create competition among providers for inclusion in a plan's network. PBMs have, through intermediation, the potential to secure lower drug prices and to improve rational prescribing...
February 16, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28209373/cost-utility-of-first-line-disease-modifying-treatments-for-relapsing-remitting-multiple-sclerosis
#7
Erkki Soini, Jaana Joutseno, Marja-Liisa Sumelahti
PURPOSE: This study evaluated the cost-effectiveness of first-line treatments of relapsing-remitting multiple sclerosis (RRMS) (dimethyl fumarate [DMF] 240 mg PO BID, teriflunomide 14 mg once daily, glatiramer acetate 20 mg SC once daily, interferon [IFN]-β1a 44 µg TIW, IFN-β1b 250 µg EOD, and IFN-β1a 30 µg IM QW) and best supportive care (BSC) in the health care payer setting in Finland. METHODS: The primary outcome was the modeled incremental cost-effectiveness ratio (ICER; €/quality-adjusted life-year [QALY] gained, 3%/y discounting)...
February 13, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28209145/state-budget-transfers-to-health-insurance-to-expand-coverage-to-people-outside-formal-sector-work-in-latin-america
#8
Inke Mathauer, Thorsten Behrendt
BACKGROUND: Contributory social health insurance for formal sector employees only has proven challenging for moving towards universal health coverage (UHC). This is because the informally employed and the poor usually remain excluded. One way to expand UHC is to fully or partially subsidize health insurance contributions for excluded population groups through government budget transfers. This paper analyses the institutional design features of such government subsidization arrangements in Latin America and assesses their performance with respect to UHC progress...
February 16, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28208730/dynamic-voltage-frequency-and-workload-joint-scaling-power-management-for-energy-harvesting-multi-core-wsn-node-soc
#9
Xiangyu Li, Nijie Xie, Xinyue Tian
This paper proposes a scheduling and power management solution for energy harvesting heterogeneous multi-core WSN node SoC such that the system continues to operate perennially and uses the harvested energy efficiently. The solution consists of a heterogeneous multi-core system oriented task scheduling algorithm and a low-complexity dynamic workload scaling and configuration optimization algorithm suitable for light-weight platforms. Moreover, considering the power consumption of most WSN applications have the characteristic of data dependent behavior, we introduce branches handling mechanism into the solution as well...
February 8, 2017: Sensors
https://www.readbyqxmd.com/read/28208227/integrating-remotely-sensed-fires-for-predicting-deforestation-for-redd
#10
Dolors Armenteras, Cerian Gibbes, Jesús A Anaya, Liliana M Dávalos
Fire is an important tool in tropical forest management, as it alters forest composition, structure, and the carbon budget. The United Nations program on Reducing Emissions from Deforestation and Forest Degradation (REDD+) aims to sustainably manage forests, as well as conserve and enhance their carbon stocks. Despite the crucial role of fire management, decision-making on REDD+ interventions fails to systematically include fires. Here, we address this critical knowledge gap in two ways. First, we review REDD+ projects and programs to assess the inclusion of fires in monitoring, reporting and verification (MRV) systems...
February 16, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28208096/how-the-structure-of-agro-food-systems-shapes-nitrogen-phosphorus-and-carbon-fluxes-the-generalized-representation-of-agro-food-system-applied-at-the-regional-scale-in-france
#11
Julia Le Noë, Gilles Billen, Josette Garnier
The aim of the study was to develop a conceptual framework to analyze the agro-food system of French agricultural regions from the angle of N, P and C circulation through five major compartments (cropland, grassland, livestock biomass, local population and potential environmental losses). To reach that goal we extended the Generalized Representation of Agro-Food System approach to P and C and applied it to French regions. Using this methodology we analyzed the relation between production pattern and N surplus, P budget, and efficient organic carbon inputs (OCeff), assuming these three indicators to be good proxies for (i) N losses to waterbodies and the atmosphere, (ii) P accumulation or depletion in soils, and (iii) potential additional C sequestration in soils, respectively...
February 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28207809/kazakhstan-can-achieve-ambitious-hiv-targets-despite-expected-donor-withdrawal-by-combining-improved-art-procurement-mechanisms-with-allocative-and-implementation-efficiencies
#12
Andrew J Shattock, Clemens Benedikt, Aliya Bokazhanova, Predrag Đurić, Irina Petrenko, Lolita Ganina, Sherrie L Kelly, Robyn M Stuart, Cliff C Kerr, Tatiana Vinichenko, Shufang Zhang, Christoph Hamelmann, Manoela Manova, Emiko Masaki, David P Wilson, Richard T Gray
BACKGROUND: Despite a non-decreasing HIV epidemic, international donors are soon expected to withdraw funding from Kazakhstan. Here we analyze how allocative, implementation, and technical efficiencies could strengthen the national HIV response under assumptions of future budget levels. METHODOLOGY: We used the Optima model to project future scenarios of the HIV epidemic in Kazakhstan that varied in future antiretroviral treatment unit costs and management expenditure-two areas identified for potential cost-reductions...
2017: PloS One
https://www.readbyqxmd.com/read/28205388/hydrogen-or-formate-alternative-key-players-in-methanogenic-degradation
#13
REVIEW
Bernhard Schink, Dominik Montag, Anja Keller, Nicolai Müller
Hydrogen and formate are important electron carriers in methanogenic degradation in anoxic environments such as sediments, sewage sludge digestors, and biogas reactors. Especially in the terminal steps of methanogenesis, they determine the energy budgets of secondary (syntrophically) fermenting bacteria and their methanogenic partners. The literature provides considerable data on hydrogen pool sizes in such habitats, but little data exist for formate concentrations due to technical difficulties in formate determination at low concentration...
February 15, 2017: Environmental Microbiology Reports
https://www.readbyqxmd.com/read/28205017/equipping-future-doctors-incorporating-management-and-leadership-into-medical-curriculums-in-the-united-kingdom
#14
Aniket Sonsale, Reshma Bharamgoudar
Throughout their careers, doctors are likely to come across complex management and leadership scenarios that many would not have had prior training in. Expectations of doctors are rising and it is becoming increasingly necessary to be able to astutely handle a variety of situations. Medical curricula must reflect this change and adapt to include the teaching of key management and leadership skills. Despite budgeting pressures, the National Health Service continues to spend vast sums of money on external management consultants...
February 15, 2017: Perspectives on Medical Education
https://www.readbyqxmd.com/read/28203120/international-lessons-in-new-methods-for-grading-and-integrating-cost-effectiveness-evidence-into-clinical-practice-guidelines
#15
REVIEW
Kathryn M Antioch, Michael F Drummond, Louis W Niessen, Hindrik Vondeling
Economic evidence is influential in health technology assessment world-wide. Clinical Practice Guidelines (CPG) can enable economists to include economic information on health care provision. Application of economic evidence in CPGs, and its integration into clinical practice and national decision making is hampered by objections from professions, paucity of economic evidence or lack of policy commitment. The use of state-of-art economic methodologies will improve this. Economic evidence can be graded by 'checklists' to establish the best evidence for decision making given methodological rigor...
2017: Cost Effectiveness and Resource Allocation: C/E
https://www.readbyqxmd.com/read/28203035/observation-based-estimates-of-global-glacier-mass-change-and-its-contribution-to-sea-level-change
#16
REVIEW
B Marzeion, N Champollion, W Haeberli, K Langley, P Leclercq, F Paul
Glaciers have strongly contributed to sea-level rise during the past century and will continue to be an important part of the sea-level budget during the twenty-first century. Here, we review the progress in estimating global glacier mass change from in situ measurements of mass and length changes, remote sensing methods, and mass balance modeling driven by climate observations. For the period before the onset of satellite observations, different strategies to overcome the uncertainty associated with monitoring only a small sample of the world's glaciers have been developed...
2017: Surveys in Geophysics
https://www.readbyqxmd.com/read/28202926/dental-public-health-capacity-worldwide-results-of-a-global-survey
#17
Marta Lomazzi, Valerie Wordley, Raman Bedi
The World Federation of Public Health Associations' Oral Health Working Group (WFPHA OHWG) carried out a survey to establish the extent of global dental public health (DPH) capacity. Senior stakeholders in DPH completed 124 surveys, covering 73 countries and all WHO regions. The survey evaluated DPH workforce within the country, funding, education, current services, and integration between public health and DPH in countries across the world. In 62 per cent of countries, DPH is only partially integrated in the public health system, while in 25 per cent of countries it has not yet been formally integrated...
December 2016: Journal of Public Health Policy
https://www.readbyqxmd.com/read/28202566/as-much-as-20-of-newfoundland-s-health-budget-may-be-inappropriately-spent
#18
Donalee Moulton
No abstract text is available yet for this article.
February 13, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28202309/working-in-scarcity-effects-on-social-interactions-and-biomedical-care-in-a-tanzanian-hospital
#19
Adrienne E Strong
Based on mixed-methods, ethnographic research in government health facilities conducted in Rukwa, Tanzania over 23 months between 2012 and 2015, this paper explores the social implications of budget shortfalls in the healthcare system at the level of a regional hospital. Budget crises resulted from the late disbursal of funds and the failure of outside donors to meet aid commitments needed to subsidize healthcare at the national level. Healthcare administrators recounted specific donors who pulled out of commitments as a direct result of foreign government austerity measures enacted after the global financial crisis of 2008...
February 7, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28199277/funding-accountable-care-in-oregon-financial-models-in-two-coordinated-care-organizations
#20
Lauren Broffman, Kristin Brown, Bruce K Bayley, Lucy Savitz, Jill Rissi
Oregon's coordinated care organizations (CCOs) are an integral part of a massive statewide reform that brings accountable care to Medicaid. CCOs are regional collaboratives among health plans, providers, county public health, and communitybased organizations that administer a single global budget covering physical, mental, and dental healthcare for low-income Oregonians. CCOs have been given freedom within the global budget to implement reforms that might capture efficiencies in cost and quality. For this study-fielded between 2012 and 2015-we traced the path of the global budget through the interior structures of two of Oregon's most promising CCOs...
July 2016: Journal of Healthcare Management / American College of Healthcare Executives
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