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https://www.readbyqxmd.com/read/28454286/suspected-tumor-to-meningioma-metastasis-a-case-report
#1
Iuri Santana Neville, Davi Fontoura Solla, Arthur Maynart Oliveira, Cesar Casarolli, Manoel Jacobsen Teixeira, Wellingson Silva Paiva
Tumor-to-meningioma metastasis (TMM) is a fairly uncommon phenomenon. Only 7 cases of prostate cancer with TMM have previously been described in the literature. The present study aimed to report a case of prostate cancer TMM, and to discuss the relevant clinical and neuroimaging aspects of this condition. A 68-year-old patient presented with headaches, poor visual acuity in the left eye and ipsilateral eyelid droop 3 years after a Simpson II resection of a left sphenoid wing meningioma. Computed tomography revealed a hyperdense area suggestive of a recurrent left sphenoid wing meningioma...
March 2017: Oncology Letters
https://www.readbyqxmd.com/read/28453997/between-a-conditional-s-antecedent-and-its-consequent-discourse-coherence-vs-probabilistic-relevance
#2
Karolina Krzyżanowska, Peter J Collins, Ulrike Hahn
Reasoning with conditionals is central to everyday life, yet there is long-standing disagreement about the meaning of the conditional. One example is the puzzle of so-called missing-link conditionals such as "if raccoons have no wings, they cannot breathe under water." Their oddity may be taken to show that conditionals require a connection between antecedent ("raccoons have no wings") and consequent ("they cannot breathe under water"), yet most accounts of conditionals attribute the oddity to natural-language pragmatics...
April 25, 2017: Cognition
https://www.readbyqxmd.com/read/28453263/strategy-for-the-realization-of-efficient-solution-processable-phosphorescent-organic-light-emitting-devices-design-and-synthesis-of-bipolar-alkynylplatinum-ii-complexes
#3
Fred Ka-Wai Kong, Man-Chung Tang, Yi-Chun Wong, Maggie Ng, Mei-Yee Chan, Vivian Wing-Wah Yam
A new class of highly luminescent bipolar alkynylplatinum(II) complexes has been synthesized, characterized, and applied as phosphorescent dopants in the fabrication of solution-processable organic light-emitting devices (OLEDs). Through the incorporation of a delicate balance of electron-donating carbazole moieties and electron-accepting phenylbenzimidazole or oxadiazole moieties into the platinum(II) core, the platinum(II) complexes have been demonstrated to exhibit bipolar charge transport character with high photoluminescence quantum yields of up to 0...
April 28, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28449112/phenotypic-variability-of-the-amazonian-species-rhodnius-brethesi-hemiptera-reduviidae
#4
A C Souza, S Catalá, A L Carbajal de la Fuente, A C V Junqueira
The wild species Rhodnius brethesi (Matta, 1919) (Hemiptera: Reduviidae) is found in areas of piassabais in microregion of Rio Negro, Amazonas, Brazil. Its geographical distribution overlaps the areas of Leopoldinia piassaba palm. In areas where palm trees are found, transmission cycle of Trypanosoma cruzi is related to the extractive activity of the palm fiber, exposing workers to wild vector transmission of this parasite. The close association with the palm tree L. piassaba suggests that this wild triatomine has special features in its sensory system allowing specificity of ecotope...
April 25, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28446656/effect-of-a-long-term-intensive-lifestyle-intervention-on-prevalence-of-cognitive-impairment
#5
Mark A Espeland, José A Luchsinger, Laura D Baker, Rebecca Neiberg, Steven E Kahn, Steven E Arnold, Rena R Wing, George L Blackburn, George Bray, Mary Evans, Helen P Hazuda, Robert W Jeffery, Valerie M Wilson, Jeanne M Clark, Mace Coday, Kathryn Demos-McDermott, John P Foreyt, Frank Greenway, James O Hill, Edward S Horton, John M Jakicic, Karen C Johnson, William C Knowler, Cora E Lewis, David M Nathan, Anne Peters, Xavier Pi-Sunyer, Henry Pownall, Thomas A Wadden, Stephen R Rapp
OBJECTIVE: To assess whether an average of 10 years of lifestyle intervention designed to reduce weight and increase physical activity lowers the prevalence of cognitive impairment among adults at increased risk due to type 2 diabetes and obesity or overweight. METHODS: Central adjudication of mild cognitive impairment and probable dementia was based on standardized cognitive test battery scores administered to 3,802 individuals who had been randomly assigned, with equal probability, to either the lifestyle intervention or the diabetes support and education control...
April 26, 2017: Neurology
https://www.readbyqxmd.com/read/28444872/saving-costs-through-a-coordinated-care-model-for-patients-with-hepatocellular-cancer
#6
Tsai-Wing Ow, Lucy Ralton, Edmund Tse
BACKGROUND: In keeping with recent trends, patients with hepatocellular cancer have had their care managed by a dedicated Nurse Coordinator at our tertiary Australian hospital since 2010. To date, there is little data to justify the cost-effectiveness of this approach. AIMS: The aim of this study is to quantify the potential cost saved through the employment of a Nurse Coordinator into the management of patients with hepatocellular carcinoma at a single tertiary-level Australian hospital...
April 26, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28444737/digest-know-your-poison-predictable-molecular-changes-confer-toxin-resistance-in-snakes
#7
Kalina T J Davies
The repeated independent evolution of similar features in divergent lineages, a process known as convergent evolution, has long been a source of fascination for both naturalists and evolutionary biologists. Until recently, this active area of research had been focused principally on the evolution of physical characteristics associated with novel traits (e.g. the independent evolution of wings in birds, bats and pterosaurs). This article is protected by copyright. All rights reserved.
April 26, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/28444691/maldi-ms-profiling-of-serum-o-and-n-glycosylation-in-cog5-cdg
#8
Angelo Palmigiano, Rosaria Ornella Bua, Rita Barone, Daisy Rymen, Luc Régal, Nicolas Deconinck, Carlo Dionisi-Vici, Cheuk-Wing Fung, Domenico Garozzo, Jaak Jaeken, Luisa Sturiale
Congenital disorders of glycosylation (CDG) are due to defective glycosylation of glycoconjugates. COG-CDG are genetic diseases due to defects of the conserved oligomeric Golgi (COG) complex subunits 1-8 causing N- and O-glycan processing abnormalities. In COG-CDG, IEF separation of undersialylated glycoforms of serum transferrin and apolipoprotein C-III (apoC-III) allows to detect N- and O-glycosylation defects respectively. COG5-CDG (COG5 subunit deficiency) is a multisystem disease with dysmorphic features, intellectual disability of variable degree, seizures, acquired microcephaly, sensory defects and autistic behavior...
April 25, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28444689/the-young-s-modulus-fracture-stress-and-fracture-strain-of-gellan-hydrogels-filled-with-whey-protein-microparticles
#9
Cherry Wing Yu Lam, Shinya Ikeda
Texture modifying abilities of whey protein microparticles are expected to be dependent on pH during heat-induced aggregation of whey protein in the microparticulation process. Therefore, whey protein microparticles were prepared at either pH 5.5 or 6.8 and their effects on small and large deformation properties of gellan gels containing whey protein microparticles as fillers were investigated. The majority of whey protein microparticles had diameters around 2 μm. Atomic force microscopy images showed that whey protein microparticles prepared at pH 6...
April 25, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28442788/changes-in-structural-and-pigmentary-colours-in-response-to-cold-stress-in-polyommatus-icarus-butterflies
#10
Krisztián Kertész, Gábor Piszter, Zsolt Endre Horváth, Zsolt Bálint, László Péter Biró
While numerous papers have investigated the effects of thermal stress on the pigmentary colours of butterfly wings, such studies regarding structural colours are mostly lacking, despite the important role they play in sexual communication. To gain insight into the possible differences between the responses of the two kinds of colouration, we investigated the effects of prolonged cold stress (cooling at 5 °C for up to 62 days) on the pupae of Polyommatus icarus butterflies. The wing surfaces coloured by photonic crystal-type nanoarchitectures (dorsal) and by pigments (ventral) showed markedly different behaviours...
April 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28442732/human-bipedal-instability-in-tree-canopy-environments-is-reduced-by-light-touch-fingertip-support
#11
L Johannsen, S R L Coward, G R Martin, A M Wing, A van Casteren, W I Sellers, A R Ennos, R H Crompton, S K S Thorpe
Whether tree canopy habitats played a sustained role in the ecology of ancestral bipedal hominins is unresolved. Some argue that arboreal bipedalism was prohibitively risky for hominins whose increasingly modern anatomy prevented them from gripping branches with their feet. Balancing on two legs is indeed challenging for humans under optimal conditions let alone in forest canopy, which is physically and visually highly dynamic. Here we quantify the impact of forest canopy characteristics on postural stability in humans...
April 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28442498/identification-and-characterization-of-a-novel-ppar%C3%AE-regulated-and-7%C3%AE-hydroxyl-bile-acid-preferring-cytosolic-sulfotransferase-ml-stl-sult2a8
#12
Lu Feng, Yee-Lok Yuen, Jian Xu, Xing Liu, Martin Yan-Chun Chan, Kai Wang, Wing-Ping Fong, Wing-Tai Cheung, Susanna Sau-Tuen Lee
PPARα has been known to play a pivotal role in orchestrating lipid, glucose, and amino acid metabolism via transcriptional regulation of its target genes expression during energy deprivation. Recent evidence also suggesting PPARα is involved in bile acid metabolism, but how PPARα modulates the homeostasis of bile acids during fasting is still not clear. In a mechanistic study aiming to dissect the spectrum of PPARα target genes involved in metabolic response to fasting, we identified a novel mouse gene (herein named mL-STL) which shared extensive homology to Sult2a subfamily of a superfamily of cytosolic sulfotransferases, implying its potential function in sulfonation...
April 25, 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/28442470/late-outcomes-in-children-with-langerhans-cell-histiocytosis
#13
Tin Wai Chow, Wing Kwan Leung, Frankie Wai Tsoi Cheng, Shekhar Medhukar Kumta, Winnie Chiu Wing Chu, Vincent Lee, Matthew Ming Kong Shing, Chi Kong Li
INTRODUCTION: Langerhans cell histiocytosis (LCH) is a rare disease with diverse clinical courses. Despite improvement in survival outcomes in the recent decades, sequelae of the disease remain a concern. This study aimed to provide information on the long-term outcomes in patients with LCH, particularly on the sequelae and any associated factors. METHOD: Medical records of patients with diagnosis of LCH and being managed in our centre were retrospectively reviewed...
April 25, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28439067/perfluorooctanesulfonate-pfos-induced-sertoli-cell-injury-through-a-disruption-of-f-actin-and-microtubule-organization-is-mediated-by-akt1-2
#14
Ying Gao, Haiqi Chen, Xiang Xiao, Wing-Yee Lui, Will M Lee, Dolores D Mruk, C Yan Cheng
PFOS (perfluorooctanesulfonate, or perfluorooctane sulfonic acid) is an anthropogenic fluorosurfactant widely used in consumer products. While its use in Europe, Canada and the U.S. has been banned due to its human toxicity, it continues to be used in China and other developing countries as a global pollutant. Herein, using an in vitro model of Sertoli cell blood-testis barrier (BTB), PFOS was found to induce Sertoli cell injury by perturbing actin cytoskeleton through changes in the spatial expression of actin regulatory proteins...
April 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28438933/pyrazinoic-acid-inhibits-a-bifunctional-enzyme-in-mycobacterium-tuberculosis
#15
Moses Njire, Na Wang, Bangxing Wang, Yaoju Tan, Xingshan Cai, Yanwen Liu, Julius Mugweru, Jintao Guo, H M Adnan Hameed, Shouyong Tan, Jianxiong Liu, Wing Wai Yew, Eric Nuermberger, Gyanu Lamichhane, Jinsong Liu, Tianyu Zhang
Pyrazinamide (PZA), an indispensable component of modern tuberculosis treatment, acts as a key sterilizing drug. While the mechanism of activation of this prodrug by Mycobacterium tuberculosis into pyrazinoic acid (POA) has been extensively studied, not all molecular determinants that confer resistance to this mysterious drug have been identified. Here, we report a new PZA resistance determinant: Asp67Asn substitution in Rv2783 confers M. tuberculosis resistance to PZA. Expression of the mutant but not the wild-type allele in M...
April 24, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28438691/niche-separation-in-flycatcher-like-species-in-the-lowland-rainforests-of-malaysia
#16
Mohammad Saiful Mansor, Rosli Ramli
Niche theory suggests that sympatric species reduce interspecific competition through segregation of shared resources by adopting different attack manoeuvres. However, the fact that flycatcher-like bird species exclusively use the sally manoeuvre may thus challenge this view. We studied the foraging ecology of three flycatcher-like species (i.e. Paradise-flycatcher Terpsiphone sp., Black-naped Monarch Hypothymis azurea, and Rufous-winged Philentoma Philentoma pyrhoptera) in the Krau Wildlife Reserve in central Peninsular Malaysia...
April 21, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/28438476/fulfilling-the-psychological-and-information-need-of-the-family-members-of-critically-ill-patients-using-interactive-mobile-technology-a-randomised-controlled-trial
#17
Vico Chung Lim Chiang, Rainbow Lai Ping Lee, Fung Mei Ho, Chi Kwong Leung, Yi Pui Tang, Wing Sze Wong, Yee Sin Ho, Yan Wai Tung, Hang Louie Lai
BACKGROUND: Intensive care nurses may have an important role in empowering families by providing psychological support and fulfilling the family's pivotal need for information. AIM: To determine whether 'education of families by tab' about the patient's condition was more associated with improved anxiety, stress, and depression levels than the 'education of families by routine'. RESEARCH DESIGN: A randomized control trial of 74 main family caregivers (intervention: 39; control: 35)...
April 21, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28437942/optical-damage-resistant-ti-diffused-zr-er-codoped-lithium-niobate-strip-waveguide-for-high-power-980-nm-pumping
#18
Wen-Bao Sun, Xiao-Fei Yang, Zi-Bo Zhang, Wing-Han Wong, Dao-Yin Yu, Edwin Yue-Bun Pun, De-Long Zhang
Ti<sup>4+</sup>-diffused Zr<sup>4+</sup>/Er<sup>3+</sup>-codoped LiNbO<sub>3</sub> strip waveguide was fabricated on an X-cut LiNbO<sub>3</sub> substrate by thermal diffusion in sequence of Er<sup>3+</sup>, Zr<sup>4+</sup> and Ti<sup>4+</sup>. Secondary ion mass spectrometry study shows that the Ti<sup>4+</sup> ions follow a sum of two error functions in the width direction and a Gauss function in the depth direction of the waveguide...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437597/weight-loss-in-weight-watchers-online-with-and-without-an-activity-tracking-device-compared-to-control-a-randomized-trial
#19
J Graham Thomas, Hollie A Raynor, Dale S Bond, Anna K Luke, Chelsi C Cardoso, Gary D Foster, Rena R Wing
OBJECTIVE: To evaluate a commercial online weight loss program and activity tracker, which are popular but have unknown efficacy. METHODS: Two hundred seventy-nine participants with BMI 27 to 40 kg/m(2) were randomized to 12 months of the Weight Watchers Online program alone (WWO) or with the ActiveLink(®) activity tracking device (WWO+AL) or an online newsletter (Control). RESULTS: Weight losses at 3 months were significantly greater in WWO (2...
April 24, 2017: Obesity
https://www.readbyqxmd.com/read/28437127/building-a-lego-wall-sequential-action-selection
#20
Amy Arnold, Alan M Wing, Pia Rotshtein
The present study draws together two distinct lines of enquiry into the selection and control of sequential action: motor sequence production and action selection in everyday tasks. Participants were asked to build 2 different Lego walls. The walls were designed to have hierarchical structures with shared and dissociated colors and spatial components. Participants built 1 wall at a time, under low and high load cognitive states. Selection times for correctly completed trials were measured using 3-dimensional motion tracking...
May 2017: Journal of Experimental Psychology. Human Perception and Performance
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