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https://www.readbyqxmd.com/read/29786423/electrochemical-determination-of-tnt-dnt-rdx-and-hmx-with-gold-nanoparticles-poly-carbazole-aniline-film-modified-glassy-carbon-sensor-electrodes-imprinted-for-molecular-recognition-of-nitroaromatics-and-nitramines
#1
Şener Sağlam, Ayşem Üzer, Erol Erçağ, Reşat Apak
Since nitroaromatic and nitramine type energetic materials, mostly arising from military activities, are persistent pollutants in soil and groundwater, on-site sensing of these hazardous chemicals has gained importance. A novel electrochemical sensor was designed for detecting nitroaromatic and nitramine type energetic materials, relying on gold nanoparticles (Aunano ) -modified glassy carbon (GC) electrode coated with nitro-energetic memory poly(carbazole-aniline) copolymer (Cz- co-ANI) film (e.g., TNT memory-GC/P(Cz- co-ANI)-Aunano modified electrode)...
May 22, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29786037/preliminary-outcome-of-individualized-abdominoperineal-excision-for-locally-advanced-low-rectal-cancer
#2
Yi Zheng, Jia-Gang Han, Zhen-Jun Wang, Zhi-Gang Gao, Guang-Hui Wei, Zhi-Wei Zhai, Bao-Cheng Zhao
Background: The introduction of individualized abdominoperineal excision (APE) may minimize operative trauma and reduce the rate of complications. The purpose of this study was to evaluate the safety and efficacy of individualized APE for low rectal cancer. Methods: Fifty-six patients who underwent individualized APE from June 2011 to June 2015 were evaluated retrospectively in Beijing Chaoyang Hospital, Capital Medical University. The main outcome measures were circumferential resection margin (CRM) involvement, intraoperative perforation, postoperative complications, and local recurrence...
June 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29785582/altered-cerebro-cerebellum-resting-state-functional-connectivity-in-hiv-infected-male-patients
#3
Huijuan Wang, Ruili Li, Yawen Zhou, Yanming Wang, Jin Cui, Benedictor Alexander Nguchu, Bensheng Qiu, Xiaoxiao Wang, Hongjun Li
In addition to the role of planning and executing movement, the cerebellum greatly contributes to cognitive process. Numerous studies have reported structural and functional abnormalities in the cerebellum for HIV-infected patients, but little is known about the altered functional connectivity of particular cerebellar subregions and the cerebrum. Therefore, this study aimed to explore the resting-state functional connectivity (rsFC) changes of the cerebellum and further analyze the relationship between the rsFC changes and the neuropsychological evaluation...
May 21, 2018: Journal of Neurovirology
https://www.readbyqxmd.com/read/29779185/predictive-role-of-measurement-of-pelvic-floor-muscle-thickness-with-static-mri-in-stress-and-mixed-urinary-incontinence
#4
Levent Yaşar, Serpil Ortakuz Telci, Keziban Doğan, Eyüp Kaya, Murat Ekin
INTRODUCTION AND HYPOTHESIS: To investigate the role of measuring the thickness of pelvic floor muscles with static MRI in the physiopathology of urinary incontinence in women with stress and mixed types of urinary incontinence diagnosed with urodynamic studies. METHODS: A retrospective clinical study was designed in collaboration with the radiology department. We recruited only patients who had undergone static pelvic MRI to determine the etiology of pelvic pain and exclude gynecologic disorders...
May 19, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29778189/antigenic-analysis-of-genetic-variants-of-canine-distemper-virus
#5
Eman Anis, Amy L Holford, Gina D Galyon, Rebecca P Wilkes
Canine distemper virus (CDV) is an RNA virus of the genus Morbillivirus within the family Paramyxoviridae. CDV produces multi-systemic disease in dogs and other terrestrial carnivores. With the development of modified live vaccines in the 1950s and 1960s, the disease, with a few exceptions, has been successfully controlled. However, recently the cases of CDV in vaccinated dogs have been increasing throughout the world, including the United States. There are many reasons that can lead to vaccine failure, including antigenic differences between the vaccine strains and the currently circulating wild-type strains...
June 2018: Veterinary Microbiology
https://www.readbyqxmd.com/read/29776752/reintroducing-opv-in-israel-on-the-journey-to-global-polio-eradication-estimation-at-a-low-rate-of-contraindicated-population
#6
Chen Rosenberg Danziger, Emilia Anis, Ethel-Sherry Gordon, Itamar Grotto, Yehuda L Danon
INTRODUCTION: The 2013 reemergence of wild poliovirus in Israel led to the reinstatement of a routine OPV vaccination. Fearing VAPP in immunocompromised, the MOH regulated contraindications for vaccination candidates and household contacts. In this study we estimate the size of the contraindicated population to OPV vaccination. METHOD: We studied vaccination candidates aged 2-9 and 14-23 months and probable household contacts. Using the rate of contraindications extracted for each study group from a medical records database, a statistical model was built to estimate the probability of contraindications in candidates...
May 15, 2018: Vaccine
https://www.readbyqxmd.com/read/29776342/dna-methylation-signatures-of-breast-cancer-in-peripheral-t-cells
#7
Surabhi Parashar, David Cheishvili, Niaz Mahmood, Ani Arakelian, Imrana Tanvir, Haseeb Ahmed Khan, Richard Kremer, Catalin Mihalcioiu, Moshe Szyf, Shafaat A Rabbani
BACKGROUND: Immune surveillance acts as a defense mechanism in cancer, and its disruption is involved in cancer progression. DNA methylation reflects the phenotypic identity of cells and recent data suggested that DNA methylation profiles of T cells and peripheral blood mononuclear cells (PBMC) are altered in cancer progression. METHODS: We enrolled 19 females with stage 1 and 2, nine with stage 3 and 4 and 9 age matched healthy women. T cells were isolated from peripheral blood and extracted DNA was subjected to Illumina 450 K DNA methylation array analysis...
May 18, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29776169/effects-of-nucleosome-stability-on-remodeler-catalyzed-repositioning
#8
Aaron M Morgan, Sarah E LeGresley, Koan Briggs, Gada Al-Ani, Christopher J Fischer
Chromatin remodelers are molecular motors that play essential roles in the regulation of nucleosome positioning and chromatin accessibility. These machines couple the energy obtained from the binding and hydrolysis of ATP to the mechanical work of manipulating chromatin structure through processes that are not completely understood. Here we present a quantitative analysis of nucleosome repositioning by the imitation switch (ISWI) chromatin remodeler and demonstrate that nucleosome stability significantly impacts the observed activity...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29776115/electroclinic-effect-in-the-chiral-lamellar-%C3%AE-phase-of-a-lyotropic-liquid-crystal
#9
Marc D Harjung, Frank Giesselmann
In thermotropic chiral Sm-A^{*} phases, an electric field along the smectic layers breaks the D_{∞} symmetry of the Sm-A^{*} phase and induces a tilt of the liquid crystal director. This so-called electroclinic effect (ECE) was first reported by Garoff and Meyer in 1977 and attracted substantial scientific and technological interest due to its linear and submicrosecond electro-optic response [S. Garoff and R. B. Meyer, Phys. Rev. A 19, 338 (1979)0556-279110.1103/PhysRevA.19.338]. We now report the observation of an ECE in the pretransitional regime from a lyotropic chiral lamellar L_{α}^{*} phase into a lyo-Sm-C^{*} phase, the lyotropic analog to the thermotropic Sm-C^{*} phase which was recently discovered by Bruckner et al...
March 2018: Physical Review. E
https://www.readbyqxmd.com/read/29774642/micropunch-blepharopeeling-versus-blepharoplasty-what-is-the-best-procedure-for-upper-eyelid-rejuvenation
#10
Ali Asilian, Behzad Bafandeh, Zabihollah Shahmoradi, Gita Faghihi, Anis Bostakian, Samaneh Mozafarpoor, Sayed Mohsen Hosseini
INTRODUCTION: Periocular rejuvenation is the most common aesthetic plastic surgery. The aim of this study was to determine effects of micropunch blepharopeeling (MBP) approach vs blepharoplasty (BP) in periocular rejuvenation. METHODS AND MATERIALS: This is a clinical trial study on 22 patients who underwent periorbital rejuvenation referred to University Skin Clinics. Patients were randomly divided into two groups of blepharoplasty or micropunch blepharopeeling...
May 17, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29772489/prevention-of-venous-thromboembolism-in-pregnant-patients-with-a-history-of-venous-thromboembolic-disease-a-retrospective-cohort-study
#11
Alejandro Lazo-Langner, Fatimah Al-Ani, Sarah Weisz, Camilla Rozanski, Martha Louzada, Judy Kovacs, Michael J Kovacs
BACKGROUND: Optimal prophylactic strategies in pregnant women with a history of venous thromboembolism (VTE) are unknown. PATIENTS AND METHODS: We conducted a retrospective cohort study of consecutive pregnant patients with a previous VTE history. Patients were followed until 6 weeks postpartum. Patients with a previous unprovoked event (including antepartum VTE) received antenatal prophylaxis, mostly with low dose low molecular weight heparin (LMWH). All patients received prophylaxis for six weeks after delivery...
May 5, 2018: Thrombosis Research
https://www.readbyqxmd.com/read/29769722/bystander-cd8-t-cells-are-abundant-and-phenotypically-distinct-in-human-tumour-infiltrates
#12
Yannick Simoni, Etienne Becht, Michael Fehlings, Chiew Yee Loh, Si-Lin Koo, Karen Wei Weng Teng, Joe Poh Sheng Yeong, Rahul Nahar, Tong Zhang, Hassen Kared, Kaibo Duan, Nicholas Ang, Michael Poidinger, Yin Yeng Lee, Anis Larbi, Alexis J Khng, Emile Tan, Cherylin Fu, Ronnie Mathew, Melissa Teo, Wan Teck Lim, Chee Keong Toh, Boon-Hean Ong, Tina Koh, Axel M Hillmer, Angela Takano, Tony Kiat Hon Lim, Eng Huat Tan, Weiwei Zhai, Daniel S W Tan, Iain Beehuat Tan, Evan W Newell
Various forms of immunotherapy, such as checkpoint blockade immunotherapy, are proving to be effective at restoring T cell-mediated immune responses that can lead to marked and sustained clinical responses, but only in some patients and cancer types1-4 . Patients and tumours may respond unpredictably to immunotherapy partly owing to heterogeneity of the immune composition and phenotypic profiles of tumour-infiltrating lymphocytes (TILs) within individual tumours and between patients5,6 . Although there is evidence that tumour-mutation-derived neoantigen-specific T cells play a role in tumour control2,4,7-10 , in most cases the antigen specificities of phenotypically diverse tumour-infiltrating T cells are largely unknown...
May 16, 2018: Nature
https://www.readbyqxmd.com/read/29767207/electrochemical-polymerization-of-pyrene-and-aniline-exclusively-inside-the-pores-of-activated-carbon-for-high-performance-asymmetric-electrochemical-capacitors
#13
Hiroyuki Itoi, Shintaro Maki, Takeru Ninomiya, Hideyuki Hasegawa, Hidenori Matsufusa, Shinya Hayashi, Hiroyuki Iwata, Yoshimi Ohzawa
An asymmetric polymer capacitor was prepared from pyrene (PY), aniline (ANI), and commercially available activated carbon (AC) through a solvent-free preparation. PY and ANI were adsorbed into the AC host material in the gas phase and electrochemically polymerized exclusively inside the AC pores in an aqueous H2SO4 electrolyte (1 M). No volumetric expansion of the AC particles occurred upon the adsorption of monomers and their subsequent polymerizations; thus, the volumetric capacitance was enhanced by the inclusion of pseudocapacitive polypyrene (PPY) and polyaniline (PANI)...
May 16, 2018: Nanoscale
https://www.readbyqxmd.com/read/29764882/postnatal-depression-and-intimate-partner-violence-a-nationwide-clinic-based-cross-sectional-study-in-malaysia
#14
Noor Ani Ahmad, Umi Adzlin Silim, Azriman Rosman, Majdah Mohamed, Ying Ying Chan, Noraida Mohd Kasim, Muslimah Yusof, Mohamad Aznuddin Abd Razak, Maisarah Omar, Fazly Azry Abdul Aziz, Rasidah Jamaluddin, Fatanah Ismail, Nurashikin Ibrahim, Tahir Aris
INTRODUCTION: An estimated 13% of women in the postnatal period suffer from postnatal depression (PND) worldwide. In addition to underprivileged women, women who are exposed to violence are at higher risk of PND. This study aimed to investigate the relationship between intimate partner violence (IPV) and PND in Malaysia. METHODS: This survey was conducted as a nationwide cross-sectional study using a cluster sampling design. Probable PND was assessed using a self-administered Edinburgh Postnatal Depression Scale (EPDS)...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29763716/prognostic-factors-in-primary-anorectal-melanoma-a-clinicopathologic-study-of-60-cases-in-china
#15
Min Ren, Yawen Lu, Jiaojie Lv, Xuxia Shen, Jincheng Kong, Bo Dai, Yunyi Kong
To investigate the clinicopathologic features and prognostic factors of primary anorectal melanoma, we described the clinical presentations, histopathology, and prognosis of 60 cases in China. Patients' age ranged from 17 to 86years with a female-to-male ratio of 2.33:1. The prevalent anatomic site of tumor was anorectum. The mean tumor thickness was 11.5mm and mean tumor size was 2.9cm. Abdominoperineal resection was performed on 38 (63.3%) patients, while wide local excision on 22 (36.7%) patients. Thirty-three (55...
May 12, 2018: Human Pathology
https://www.readbyqxmd.com/read/29762065/reliability-of-the-arabic-smartphone-addiction-scale-and-smartphone-addiction-scale-short-version-in-two-different-moroccan-samples
#16
Anis Sfendla, Meriame Laita, Basma Nejjar, Zouhayr Souirti, Ahami Ahmed Omar Touhami, Meftaha Senhaji
The extensive accessibility to smartphones in the last decade raises the concerns of addictive behavior patterns toward these technologies worldwide and in developing countries, and Arabic ones in particular. In an area of stigmatized behavior such as Internet and smartphone addiction, the hypothesis extends to whether there is a reliable instrument that can assess smartphone addiction. To our knowledge, no scale in Arabic language is available to assess maladaptive behavior associated with smartphone use. This study aims to assess the factorial validity and internal reliability of the Arabic Smartphone Addiction Scale (SAS) and Smartphone Addiction Scale-Short Version (SAS-SV) in a Moroccan surveyed population...
May 2018: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/29757987/genomic-regions-analysis-of-seedling-root-traits-and-their-regulation-in-responses-to-phosphorus-deficiency-tolerance-in-cssl-population-of-elite-super-hybrid-rice
#17
Galal Bakr Anis, Yingxin Zhang, Huimin Wang, Zihe Li, Weixun Wu, Lianping Sun, Aamir Riaz, Liyong Cao, Shihua Cheng
Phosphorus (P) is the essential macro-element supporting rice productivity. Quantitative trait loci (QTL) underlying related traits at the seedling stage under two different phosphorus levels was investigated in rice using a population of 76 Chromosomal Sequence Substitution Lines (CSSLs) derived from a cross between the maintainer variety XieqingzaoB (P stress tolerant) and the restorer variety Zhonghui9308 (P stress sensitive); the parents of super hybrid rice Xieyou9308. A genetic linkage map with 120 DNA marker loci was constructed...
May 14, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29757662/a-review-of-the-surgical-management-of-perineal-hernias-in-dogs
#18
Sukhjit Singh Gill, Robert D Barstad
Perineal hernia refers to the failure of the muscular pelvic diaphragm to support the rectal wall, resulting in herniation of pelvic and, occasionally, abdominal viscera into the subcutaneous perineal region. The proposed causes of pelvic diaphragm weakness include tenesmus associated with chronic prostatic disease or constipation, myopathy, rectal abnormalities, and gonadal hormonal imbalances. The most common presentation of perineal hernia in dogs is a unilateral or bilateral nonpainful swelling of the perineum...
May 14, 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29756750/validation-of-the-pmd100tm-and-its-noltm-index-to-detect-nociception-at-different-infusion-regimen-of-remifentanil-in-patients-under-general-anaesthesia
#19
Pierre-André Stöckle, Marco Julien, Rami Issa, Elizabeth Décary, Véronique Brulotte, Pierre Drolet, Margaret Henri, Madeleine Poirier, Jean-François Latulippe, Marc Dorais, Olivier Verdonck, Louis-Philippe Fortier, Philippe Richebé
BACKGROUND: The NOL index is based on multiparametric analysis of heart rate (HR), skin conductance, wave plethysmography, and their time derivative. Our objective was to evaluate the NOL to detect standardized nociceptive stimuli with various remifentanil dosages under general anaesthesia. METHODS: A prospective, observational study at a single center (NCT02602379) included 40 ASA I to III patients undergoing laparotomy under remifentanil-desflurane anaesthesia with epidural analgesia...
May 14, 2018: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29755434/a-polyphasic-and-taxogenomic-evaluation-uncovers-arcobacter-cryaerophilus-as-a-species-complex-that-embraces-four-genomovars
#20
Alba Pérez-Cataluña, Luis Collado, Oscar Salgado, Violeta Lefiñanco, María J Figueras
The species Arcobacter cryaerophilus is found in many food products of animal origin and is the dominating species in wastewater. In addition, it is associated with cases of farm animal and human infectious diseases,. The species embraces two subgroups i.e., 1A (LMG 24291T = LMG 9904T ) and 1B (LMG 10829) that can be differentiated by their 16S rRNA-RFLP pattern. However, some authors, on the basis of the shared intermediate levels of DNA-DNA hybridization, have suggested abandoning the subgroup classification...
2018: Frontiers in Microbiology
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