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https://www.readbyqxmd.com/read/28818650/recombinant-vs-native-anisakis-haemoglobin-ani-s-13-its-appraisal-as-a-new-gold-standard-for-the-diagnosis-of-allergy
#1
Juan González-Fernández, Luis Rivas, Juan Román Luque-Ortega, Rafael Núñez-Ramírez, Pamela Campioli, Teresa Gárate, María J Perteguer, Alvaro Daschner, Carmen Cuéllar
Recombinant allergens are currently the best option for serodiagnosis of human anisakiasis in terms of sensitivity and specificity. However, previous reports showed high rates of anisakiasis patients who were negative to Ani s 7 and especially to Ani s 1. Recently, Anisakis haemoglobin was described as a major allergen (Ani s 13). Although Ani s 13 belongs to a conserved protein family, it seems not to be a cross-reacting antigen because of the absence of IgE recognition against Ascaris haemoglobin in Anisakis patients...
August 14, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28811144/microwave-induced-plasma-for-solid-fuels-and-waste-processing-a-review-on-affecting-factors-and-performance-criteria
#2
REVIEW
Guan Sem Ho, Hasan Mohd Faizal, Farid Nasir Ani
High temperature thermal plasma has a major drawback which consumes high energy. Therefore, non-thermal plasma which uses comparatively lower energy, for instance, microwave plasma is more attractive to be applied in gasification process. Microwave-induced plasma gasification also carries the advantages in terms of simplicity, compactness, lightweight, uniform heating and the ability to operate under atmospheric pressure that gains attention from researchers. The present paper synthesizes the current knowledge available for microwave plasma gasification on solid fuels and waste, specifically on affecting parameters and their performance...
August 12, 2017: Waste Management
https://www.readbyqxmd.com/read/28811000/a-case-of-cutaneous-leishmaniasis-guyanensis-mimicking-otitis-externa
#3
Eric S Goodrich, Stephen C Sears, Timothy Sorrells, James K Radike, Anis Miladi, Jonathan S Glass
Cutaneous leishmaniasis typically presents as a painless papule progressing to an ulcer or plaque. In this case study of the ear, the disease manifested as a small painful bump progressing into redness and swelling about the ear with purulent drainage. After multiple oral/intravenous antipseudomonal, antistaphylococcal, and antifungal treatments, there was no improvement. The skin progressed to an erythematous plaque and hemorrhagic ulcer; punch biopsy and speciation revealed Leishmaniasis guyanensis. The patient was switched to a seven-dose course of intravenous L-amphotericin B (visceral leishmaniasis protocol)...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28809146/mycobacterium-talmoniae-sp-nov-a-slowly-growing-mycobacterium-isolated-from-human-respiratory-samples
#4
Rebecca M Davidson, Mary Ann DeGroote, Jamie L Marola, Sarah Buss, Victoria Jones, Michael R McNeil, Alison G Freifeld, L Elaine Epperson, Nabeeh A Hasan, Mary Jackson, Peter C Iwen, Max Salfinger, Michael Strong
A novel slowly growing, non-chromogenic species of the class Actinobacteria was isolated from a human respiratory sample in Nebraska, USA, in 2012. Analysis of the internal transcribed spacer sequence supported placement into the genus Mycobacterium with high sequence similarity to a previously undescribed strain isolated from a patient respiratory sample from Oregon, USA, held in a collection in Colorado, USA, in 2000. The two isolates were subjected to phenotypic testing and whole genome sequencing and found to be indistinguishable...
August 15, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28806615/graphene-gold-based-nanocomposites-applications-in-cancer-diseases-efficient-detection-and-therapeutic-tools
#5
REVIEW
Lina A Al-Ani, Mohammed A AlSaadi, Farkaad A Kadir, Najihah M Hashim, Nurhidayatullaili M Julkapli, Wageeh A Yehye
Early detection and efficient treatment of cancer disease remains a drastic challenge in 21st century. Throughout the bulk of funds, studies, and current therapeutics, cancer seems to aggressively advance with drug resistance strains and recurrence rates. Nevertheless, nanotechnologies have indeed given hope to be the next generation for oncology applications. According to US National cancer institute, it is anticipated to revolutionize the perspectives of cancer diagnosis and therapy. With such success, nano-hybrid strategy creates a marvelous preference...
July 28, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28800752/a-type-i-combi-targeting-approach-for-the-design-of-molecules-with-enhanced-potency-against-brca1-2-mutant-and-o6-methylguanine-dna-methyltransferase-mgmt-expressing-tumour-cells
#6
Zhor Senhaji Mouhri, Elliot Goodfellow, Bertrand Jean-Claude
BACKGROUND: Mutations of the DNA repair proteins BRCA1/2 are synthetically lethal with the DNA repair enzyme poly(ADP-ribose) polymerase (PARP), which when inhibited, leads to cell death due to the absence of compensatory DNA repair mechanism. The potency of PARP inhibitors has now been clinically proven. However, disappointingly, acquired resistance mediated by the reactivation of wild type BRCA1/2 has been reported. In order to improve their efficacy, trials are ongoing to explore their combinations with temozolomide (TMZ)...
August 11, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28800636/combined-sprint-and-resistance-training-abrogates-age-differences-in-somatotropic-hormones
#7
Maha Sellami, Wissem Dhahbi, Lawrence D Hayes, Johnny Padulo, Fatma Rhibi, Hanen Djemail, Anis Chaouachi
The aim of this investigation was to compare serum growth hormone (GH), insulin-like growth factor-1 (IGF-1) and insulin-like growth factor-binding protein-3 (IGFBP-3) in response to a combined sprint and resistance training (CSRT) program in young and middle-aged men.Thirty-eight healthy, moderately trained men participated in this study. Young and middle-aged men were randomly assigned to, a young training group (YT = 10, 21.4±1.2yrs) ora young control group (YC = 9, 21.6±1.8 yrs), a middle-aged training group (MAT = 10, 40...
2017: PloS One
https://www.readbyqxmd.com/read/28798737/complete-genome-analysis-of-thermus-parvatiensis-and-comparative-genomics-of-thermus-spp-provide-insights-into-genetic-variability-and-evolution-of-natural-competence-as-strategic-survival-attributes
#8
Charu Tripathi, Harshita Mishra, Himani Khurana, Vatsala Dwivedi, Komal Kamra, Ram K Negi, Rup Lal
Thermophilic environments represent an interesting niche. Among thermophiles, the genus Thermus is among the most studied genera. In this study, we have sequenced the genome of Thermus parvatiensis strain RL, a thermophile isolated from Himalayan hot water springs (temperature >96°C) using PacBio RSII SMRT technique. The small genome (2.01 Mbp) comprises a chromosome (1.87 Mbp) and a plasmid (143 Kbp), designated in this study as pTP143. Annotation revealed a high number of repair genes, a squeezed genome but containing highly plastic plasmid with transposases, integrases, mobile elements and hypothetical proteins (44%)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28796199/markers-of-t-cell-senescence-in-humans
#9
REVIEW
Weili Xu, Anis Larbi
Many countries are facing the aging of their population, and many more will face a similar obstacle in the near future, which could be a burden to many healthcare systems. Increased susceptibility to infections, cardiovascular and neurodegenerative disease, cancer as well as reduced efficacy of vaccination are important matters for researchers in the field of aging. As older adults show higher prevalence for a variety of diseases, this also implies higher risk of complications, including nosocomial infections, slower recovery and sequels that may reduce the autonomy and overall quality of life of older adults...
August 10, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28792984/diretriz-da-sociedade-brasileira-de-cardiologia-e-da-sociedade-brasileira-de-hemodin%C3%A3-mica-e-cardiologia-intervencionista-sobre-interven%C3%A3-%C3%A3-o-coron%C3%A3-ria-percut%C3%A3-nea
#10
Fausto Feres, Ricardo A Costa, Dimytri Siqueira, J Ribamar Costa, Daniel Chamié, Rodolfo Staico, Áurea J Chaves, Alexandre Abizaid, José Antônio Marin-Neto, Anis Rassi, Roberto Botelho, Cláudia Maria Rodrigues Alves, Jamil Abdalla Saad, José A Mangione, Pedro A Lemos, Alexandre S Quadros, Marcelo A Cartaxo Queiroga, Marcelo J C Cantarelli, Hélio Roque Figueira
No abstract text is available yet for this article.
June 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28792367/proposal-of-nine-novel-species-of-the-bacillus-cereus-group
#11
Yang Liu, Juan Du, Qiliang Lai, Runying Zeng, Dezan Ye, Jun Xu, Zongze Shao
Nine novel Gram-stain-positive bacteria were investigated by a polyphasic taxonomic approach. Based on the analysis of 16S rRNA gene sequences, these strains belonged to the Bacillus cereus group, sharing over 97 % similarity with the known species of this group, and less than 95 % similarity with other species of the genus Bacillus. Multilocus sequence typing analysis showed that they formed nine robust and well-separated branches from the known species. The digital DNA-DNA hybridization (dDDH) and average nucleotide identity (ANI) values between the nine strains were, respectively, below the 70 and 96 % threshold values for species definition, and between each strain and the known type strains of this group were also below the two threshold values...
August 10, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28791064/validation-of-farsi-translation-of-the-ocular-surface-disease-index
#12
Farzad Pakdel, Mahmood Reza Gohari, Anis Sadat Jazayeri, Afsaneh Amani, Niloofar Pirmarzdashti, Hossein Aghaee
PURPOSE: To develop and validate a Farsi version of Ocular Surface Disease Index (OSDI) for the Iranian population. METHODS: This study was a translation and cross-cultural adaptation and validation of Farsi version of OSDI. Four bilingual (English-Persian) individual including three physicians and one native English teacher were asked to translate the original English OSDI questionnaire in Farsi. Following back and forth translation, integration and pilot check, the translation team came to consensus on translation...
July 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28780739/levetiracetam-versus-phenytoin-for-seizure-prophylaxis-in-brain-injured-patients-a-systematic-review-and-meta-analysis
#13
Anis Chaari, Alaa Sayed Mohamed, Karim Abdelhakim, Vipin Kauts, William Francis Casey
Background The onset of early and/or late seizures in brain injured patients is associated with worse outcome. So far, phenytoin is the most commonly used antiepileptic drug to prevent seizures in this group of patients. Objective In the current metaanalysis, we aimed to compare the efficacy and safety of phenytoin versus levetiracetam for seizure prophylaxis in brain injured patients. Methods A systematic search was conducted in PubMed and Cochrane Library Database by 2 investigators. Four randomized controlled trials (RCTs) were included (295 patients)...
August 5, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28777750/polymorphonuclear-neutrophil-functions-are-differentially-altered-in-amnestic-mild-cognitive-impairment-and-mild-alzheimer-s-disease-patients
#14
Aurélie Le Page, Julie Lamoureux, Karine Bourgade, Eric H Frost, Graham Pawelec, Jacek M Witkowski, Anis Larbi, Gilles Dupuis, Tamàs Fülöp
The mechanisms of neurodegeneration in Alzheimer's disease (AD) remain under investigations. Alterations in the blood-brain barrier facilitate exchanges of inflammatory mediators and immune cells between the brain and the periphery in AD. Here, we report analysis of phenotype and functions of polymorphonuclear neutrophils (PMN) in peripheral blood in amnestic mild cognitive impairment (aMCI, n = 13), patients with mild AD (mAD, n = 15), and healthy elderly controls (n = 13). Results showed an increased expression of CD177 in mAD but not in healthy or aMCI patients...
July 29, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28776327/helicobacter-pylori-outer-inflammatory-protein-a-oipa-suppresses-apoptosis-of-ags-gastric-cells-in-vitro
#15
Anis Rageh Al-Maleki, Mun Fai Loke, Sook Yin Lui, Nur Siti Khadijah Ramli, Yalda Khosravi, Chow Goon Ng, Gopinath Venkatraman, Khean-Lee Goh, Bow Ho, Jamuna Vadivelu
Outer Inflammatory Protein A (OipA) is an important virulence factor associated with gastric cancer and ulcer development, however the results has not been well-established and turned out to be controversial. This study aims to elucidate the role of OipA in H. pylori infection using clinical strains harboring oipA "on" and "off" motifs. Proteomics analysis was performed on AGS cell pre and post-infection with H. pylori oipA "on" and "off" strains, using liquid chromatography / mass spectrometry. AGS apoptosis and cell cycle assays were performed...
August 3, 2017: Cellular Microbiology
https://www.readbyqxmd.com/read/28774297/citrus-lemon-essential-oil-chemical-composition-antioxidant-and-antimicrobial-activities-with-its-preservative-effect-against-listeria-monocytogenes-inoculated-in-minced-beef-meat
#16
Anis Ben Hsouna, Nihed Ben Halima, Slim Smaoui, Naceur Hamdi
BACKGROUND: Lemon (Citrus limon) is a flowing plant belonging to the Rutaceae family. Citrus plants constitute one of the main valuable sources of essential oil used in foods and medicinal purposes. METHODS: In this study, we assessed chemical composition, antioxidant and antimicrobial activities of C. limon essential oil (ClEO) with its preservative effect against Listeria monocytogenes inoculated in minced beef meat. Gas chromatography/mass spectrometry (GC-MS) was used to identify the major components of the obtained ClEO...
August 3, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28770445/actinoalloteichus-fjordicus-sp-nov-isolated-from-marine-sponges-phenotypic-chemotaxonomic-and-genomic-characterisation
#17
Imen Nouioui, Christian Rückert, Joost Willemse, Gilles P van Wezel, Hans-Peter Klenk, Tobias Busche, Jörn Kalinowski, Harald Bredholt, Sergey B Zotchev
Two actinobacterial strains, ADI 127-17(T) and GBA 129-24, isolated from marine sponges Antho dichotoma and Geodia barretti, respectively, collected at the Trondheim fjord in Norway, were the subjects of a polyphasic study. According to their 16S rRNA gene sequences, the new isolates were preliminarily classified as belonging to the genus Actinoalloteichus. Both strains formed a distinct branch, closely related to the type strains of Actinoalloteichus hoggarensis and Actinoalloteichus hymeniacidonis, within the evolutionary radiation of the genus Actinoalloteichus in the 16S rRNA gene-based phylogenetic tree...
August 2, 2017: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/28764637/invasive-anisakiasis-by-the-parasite-anisakis-pegreffii-nematoda-anisakidae-diagnosis-by-real-time-pcr-hydrolysis-probe-system-and-immunoblotting-assay
#18
Simonetta Mattiucci, Michela Paoletti, Alessandra Colantoni, Antonella Carbone, Raffaele Gaeta, Agnese Proietti, Stefano Frattaroli, Paolo Fazii, Fabrizio Bruschi, Giuseppe Nascetti
BACKGROUND: Anisakiasis is a fish-borne zoonosis caused by Anisakis spp. larvae. One challenging issue in the diagnosis of anisakiasis is the molecular detection of the etiological agent even at very low quantity, such as in gastric or intestinal biopsy and granulomas. Aims of this study were: 1) to identify three new cases of invasive anisakiasis, by a species-specific Real-time PCR probe assay; 2) to detect immune response of the patients against the pathogen. METHODS: Parasite DNA was extracted from parasites removed in the three patients...
August 1, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28762179/vaginal-laxity-what-does-this-symptom-mean
#19
Hans Peter Dietz, Martyna Stankiewicz, Ixora Kamisan Atan, Caroline Wanderley Ferreira, Maciej Socha
INTRODUCTION AND HYPOTHESIS: Vaginal laxity is a poorly understood symptom of pelvic floor dysfunction. The purpose of this study was to investigate associations between the symptom of vaginal laxity and its bother on the one hand, and demographic data, other symptoms, and findings on examination on the other hand. METHODS: This was a retrospective observational study at a tertiary urogynecological unit. A total of 337 patients were seen for a standardized interview, clinical examination (ICS POP-Q) and 4D translabial ultrasonography...
July 31, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28761634/acute-beriberi-neuropathy-mimicking-guillain-barr%C3%A3-syndrome-after-a-strict-vegetarian-diet
#20
Anis Riahi, Malek Mansour, Ines Bedoui, Hajer Derbali, Mariem Messelmani, Jamel Zaouali, Ridha Mrissa
No abstract text is available yet for this article.
April 4, 2017: Iranian Journal of Neurology
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