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pancreatic divisum

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https://www.readbyqxmd.com/read/28871465/the-crossing-duct-sign
#1
REVIEW
Yan-Lin Li, Man-Leung Yu, Kam-Ho Lee
Pancreas divisum is a common variation in pancreatic ductal anatomy present in up to 10% of the population with variable clinical importance. The crossing duct sign refers to the appearance of dominant dorsal duct crossing the intrapancreatic common bile duct to empty into the minor papilla, best illustrated on maximum intensity projection images from MRCP.
September 4, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28845111/the-efficacy-of-endoscopic-therapy-for-pancreas-divisum-a-meta-analysis
#2
Lamprinos Michailidis, Bilal Aslam, Alla Grigorian, Houssam Mardini
BACKGROUND: The purpose of this study was to perform a meta-analysis assessing the efficacy and predictors of success of endoscopic therapy in the management of patients with pancreas divisum. METHODS: An electronic database search (PubMed and ScienceDirect) was performed for relevant studies. Studies were selected based on predefined criteria and data were extracted on patient population, follow up, endotherapy methods, success rates and complication rates. A random-effect model was used to pool the effect size across studies...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28685743/stent-drainage-achieved-by-endoscopic-ultrasonography-guided-puncture-from-duodenal-bulb-to-the-minor-pancreatic-duct-for-the-treatment-of-acute-epigastric-pain-in-a-patient-with-pancreas-divisum
#3
Bin Cheng, Demin Li, Xiaoli Wu, Zhicheng Zhang, Min Zhang, Min Yang, Qiaozhen Guo, Qiu Zhao
No abstract text is available yet for this article.
July 6, 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28449428/a-rare-case-of-pancreas-divisum-accompanied-by-acute-pancreatitis-following-endoscopic-hemostasis-for-duodenal-ulcer-bleeding
#4
Yong Hyeok Choi, Soon Man Yoon, Eun Bee Kim, Youngmin Oh, Keunmo Kim, Jisun Lee, Seon Mee Park, Sei Jin Youn
Peptic ulcer bleeding is treated using endoscopic hemostasis using clips or bands. Pancreas divisum (PD), a congenital anomaly of the pancreas, usually has no clinical symptoms; however, pancreatitis may occur if there are disturbances in the drainage of pancreatic secretions. We report an unusual case of PD accompanied by acute pancreatitis, following endoscopic band ligation for duodenal ulcer bleeding. A 48-year-old woman was admitted to our hospital due to melena. An upper endoscopy revealed a small ulcer with oozing adjacent minor papilla...
April 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28355667/pancreas-divisum-in-children-and-duodenum-preserving-resection-of-the-pancreatic-head
#5
Jiri Snajdauf, Ondrej Petru, Jiri Nahlovsky, Michal Rygl, Barbora Frybova, Jiri Bronsky, Vladimir Mixa, Radan Keil
Introduction A retrospective study was performed to evaluate the clinical features, diagnostic methods, and treatment alternatives in children with pancreas divisum (PD). Materials and Methods Patients who underwent treatment for PD between 1999 and 2014 at our department were evaluated for sex, age, presenting symptoms, physical examination findings, biochemical markers, diagnostic methods, treatment modalities, and results of treatment during follow-up. Results Seven patients who underwent treatment of symptomatic PD were included in the study...
March 29, 2017: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28320629/is-acute-recurrent-pancreatitis-in-children-a-precursor-of-chronic-pancreatitis-a-long-term-follow-up-study-of-93-cases
#6
Ujjal Poddar, Surender K Yachha, Vibhor Borkar, Anshu Srivastava
BACKGROUND/AIMS: In view of paucity of literature we analyzed our experience of acute recurrent pancreatitis (ARP) to study clinical profile and long-term outcome. METHODS: Over 13 years, 93 consecutive children (≤18 years) diagnosed to have ARP were included in this study. Magnetic resonance cholangiopancreatography was done at baseline and on follow-up. Common mutations for serine-protease-inhibitor (SPINK1 N34S), protease inhibitor (PRSS1 R122S) and cystic fibrosis transmembrane conductance regulator (CFTR deltaF508, 5T) were studied in 22 idiopathic cases...
July 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28317046/a-rare-case-of-choledochal-cyst-with-pancreas-divisum-case-presentation-and-literature-review
#7
Adrián Ransom-Rodríguez, Ruben Blachman-Braun, Emilio Sánchez-García Ramos, Jesús Varela-Prieto, Erick Rosas-Lezama, Miguel Ángel Mercado
Choledochal cysts are rare congenital malformations of the bile duct characterized by dilatations of the intrahepatic and/or extrahepatic portion of the biliary tree, they are associated to an anomalous arrangement of the pancreaticobiliary duct. Pancreas divisum results from a fusion failure of the pancreatic buds. The coexistence of pancreas divisum and choledochal cyst in adults has been reported in less than 10 well documented cases. This article presents a case of a 42-year-old Peruvian man with intermittent episodes of abdominal pain, initially diagnosed with choledocholithiasis, who underwent open cholecystectomy...
February 2017: Annals of Hepato-Biliary-Pancreatic Surgery
https://www.readbyqxmd.com/read/28291989/reverse-sphincterotomy-of-the-minor-papilla-via-the-major-papilla-for-chronic-pancreatitis-with-incomplete-pancreas-divisum
#8
Radhika Chavan, Rakesh Kalapala, Zaheer Nabi, Sundeep Lakhtakia, D Nageshwar Reddy
No abstract text is available yet for this article.
February 2017: Endoscopy
https://www.readbyqxmd.com/read/28241234/laparoscopic-total-pancreatectomy-with-islet-autotransplantation-and-intraoperative-islet-separation-as-a-treatment-for-patients-with-chronic-pancreatitis
#9
Caleb J Fan, Kenzo Hirose, Christi M Walsh, Michael Quartuccio, Niraj M Desai, Vikesh K Singh, Rita R Kalyani, Daniel S Warren, Zhaoli Sun, Marie N Hanna, Martin A Makary
Importance: Pain management of patients with chronic pancreatitis (CP) can be challenging. Laparoscopy has been associated with markedly reduced postoperative pain but has not been widely applied to total pancreatectomy with islet autotransplantation (TPIAT). Objective: To examine the feasibility of using laparoscopic TPIAT (L-TPIAT) in the treatment of CP. Design, Setting, and Participants: Thirty-two patients with CP presented for TPIAT at a tertiary hospital from January 1, 2013, through December 31, 2015...
June 1, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28188033/success-and-safety-of-endoscopic-retrograde-cholangiopancreatography-in-children
#10
Jordan D Rosen, Rebecca S Lane, Jose M Martinez, Eduardo A Perez, Jun Tashiro, Amy E Wagenaar, Robert M Van Haren, Ashwini Kumar, Juan E Sola
PURPOSE: Despite its diagnostic and therapeutic utility, endoscopic retrograde cholangiopancreatography (ERCP) is underutilized in children. METHODS: Patients younger than 18years undergoing ERCP from 2000 to 2014 at a children's hospital were identified. Patient characteristics and outcomes were evaluated. RESULTS: Overall, 215 ERCPs (78% therapeutic) were performed in 184 patients. Our cohort was 67% female, with a median age (IQR) of 14 (8) years...
July 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28135676/horizontal-traumatic-laceration-of-the-pancreas-head-a-rare-case-report
#11
Atsushi Nanashima, Naoya Imamura, Yuki Tsuchimochi, Takeomi Hamada, Kouichi Yano, Masahide Hiyoshi, Yoshiro Fujii, Fumiaki Kawano, MitsuruTamura
INTRODUCTION: This case report is intended to inform acute care surgeons about treating rare horizontal laceration of the pancreas head caused by blunt trauma. CASE PRESENTATION: A 57-year-old woman who sustained blunt abdominal trauma during a car crash was transported to the emergency center of our hospital with unstable vital signs due to hemorrhagic shock. Computed tomography showed transection of the pancreas head and massive intra-abdominal hemorrhage. She was referred for emergency surgery because of a transient response...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28110914/a-systematic-review-and-quantitative-analysis-of-different-therapies-for-pancreas-divisum
#12
REVIEW
Mohammadreza Hafezi, Bartosch Mayschak, Pascal Probst, Markus W Büchler, Thilo Hackert, Arianeb Mehrabi
BACKGROUND: Pancreas divisum is the most common anatomical variation of pancreatic ductal system affecting 5-10% of population. Therapy includes different endoscopic and surgical procedures. The aim of this article was to summarize actual evidence of different treatment. METHODS: A Medline search was performed to identify all studies, investigating endoscopic or surgical therapy of Pancreas divisum. An individual data simulation model was applied to compare endoscopic and surgical studies...
September 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/27938531/pancreas-divisum-correlation-between-anatomical-abnormalities-and-bile-precipitation-in-the-gallbladder-in-seven-patients
#13
P Izzo, P Di Cello, F Pugliese, S Izzo, Romualdo Grande, F Biancucci, G Sinaimeri, F Razionale, U Costi, M Al Mansour, A Muneer, S Valabrega, L Izzo
Pancreas divisum is a genetic defect associated with recurrent acute pancreatitis due to insufficient drainage of the accessory pancreatic duct. Seven young patients diagnosed with pancreatic divisum and thickening of the gallbladder bile as shown on magnetic resonance cholangio-pancreatography without pancreatic ductal changes underwent laparoscopic cholecystectomy. During the mean follow-up of 32 months no episode of pancreatitis was reported. There is an association between PD and higher concentration of bile in the gallbladder...
July 2016: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/27926364/chronic-pancreatitis
#14
REVIEW
Michelle Stram, Shu Liu, Aatur D Singhi
Chronic pancreatitis is a debilitating condition often associated with severe abdominal pain and exocrine and endocrine dysfunction. The underlying cause is multifactorial and involves complex interaction of environmental, genetic, and/or other risk factors. The pathology is dependent on the underlying pathogenesis of the disease. This review describes the clinical, gross, and microscopic findings of the main subtypes of chronic pancreatitis: alcoholic chronic pancreatitis, obstructive chronic pancreatitis, paraduodenal ("groove") pancreatitis, pancreatic divisum, autoimmune pancreatitis, and genetic factors associated with chronic pancreatitis...
December 2016: Surgical Pathology Clinics
https://www.readbyqxmd.com/read/27904444/anatomic-variations-of-the-pancreatic-duct-and-their-relevance-with-the-cambridge-classification-system-mrcp-findings-of-1158-consecutive-patients
#15
Zehra Hilal Adibelli, Mustafa Adatepe, Cetin Imamoglu, Ozgur Sipahi Esen, Nazif Erkan, Mehmet Yildirim
BACKGROUND: The study was conducted to evaluate the frequencies of the anatomic variations and the gender distributions of these variations of the pancreatic duct and their relevance with the Cambridge classification system as morphological sign of chronic pancreatitis using magnetic resonance cholangiopancreatography (MRCP). PATIENTS AND METHODS: We retrospectively reviewed 1312 consecutive patients who referred to our department for MRCP between January 2013 and August 2015...
December 1, 2016: Radiology and Oncology
https://www.readbyqxmd.com/read/27888858/novel-findings-in-the-management-of-acute-pancreatitis
#16
Federico Bolado, Enrique de-Madaria
Acute pancreatitis (AP) is a potentially serious disease whose incidence is on the increase. Pancreas divisum does not meet the required criteria to be considered an aetiological factor. Sphincter of Oddi dysfunction may be another cause of idiopathic AP. Less invasive methods cannot replace Sphincter of Oddi manometry in diagnosis. Almost half of patients with systemic inflammatory response syndrome develop organ failure, but the mechanisms involved are not completely understood. Obesity is a risk factor for severity in AP; the cause could be the presence of free unsaturated fatty acids, which have pro-inflammatory activity...
September 2016: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/27846144/low-alcohol-and-cigarette-use-is-associated-to-the-risk-of-developing-chronic-pancreatitis
#17
Milena Di Leo, Gioacchino Leandro, Satish K Singh, Alberto Mariani, Margherita Bianco, Raffaella Alessia Zuppardo, Elisabetta Goni, Teresa Marzia Rogger, Francesco Di Mario, Mario Guslandi, Francesco De Cobelli, Alessandro Del Maschio, Pier Alberto Testoni, Giulia Martina Cavestro
OBJECTIVES: The aim of this study was to investigate the contribution of smoking and alcohol intake and pancreas divisum on the risk of developing chronic pancreatitis (CP). METHODS: Consecutive patients with CP who underwent secretin-enhanced magnetic resonance cholangiopancreatography were compared with consecutive patients without pancreatic disease who underwent secretin-enhanced magnetic resonance cholangiopancreatography for irritable bowel syndrome. RESULTS: We enrolled 145 consecutive CP patients and 103 irritable bowel syndrome patients from 2010 to 2014...
February 2017: Pancreas
https://www.readbyqxmd.com/read/27829604/an-impacted-minor-papilla-stone-in-a-patient-with-pancreas-divisum-that-caused-acute-exacerbation-of-chronic-pancreatitis-a-case-report
#18
Yoshiaki Isono, Shimpei Matsusaki, Hiroki Tanaka, Tomomasa Tochio, Hiroaki Kumazawa, Tomohiro Sase, Tomonori Saito, Hiroshi Okano, Youichirou Baba, Katsumi Mukai
A 75-year-old woman with epigastric pain was admitted to our emergency department. She was diagnosed with an acute exacerbation of chronic pancreatitis based on the results of blood tests and abdominal computed tomography (CT). The abdominal CT and magnetic resonance cholangiopancreatography revealed pancreas divisum. Abdominal CT also showed a stone in the minor papilla, with impaction of the stone being the most likely cause of the acute episode. Therefore, endoscopic sphincterotomy of the minor papilla and endoscopic naso-pancreatic duct drainage were performed to remove the stone and decrease the internal pressure of the pancreatic duct...
2016: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/27824485/the-value-of-secretin-enhanced-mrcp-in-patients-with-recurrent-acute-pancreatitis
#19
Kumar Sandrasegaran, Bilal Tahir, Udaykamal Barad, Evan Fogel, Fatih Akisik, Temel Tirkes, Stuart Sherman
OBJECTIVE: The purpose of this study is to assess the additional value of secretin-enhanced MRCP over conventional (non-secretin-enhanced) MRCP in diagnosing disease in patients with recurrent acute pancreatitis. MATERIALS AND METHODS: A retrospective review of a radiology database found 72 patients with recurrent acute pancreatitis who had secretin-enhanced MRCP and ERCP correlation within 3 months of each other between January 2007 and December 2011. Of these patients, 54 had no history of pancreatic tumor or surgery and underwent MRI more than 3 months after an episode of acute pancreatitis...
February 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/27817166/acute-obstructive-pancreatitis-after-pancreas-sparing-total-duodenectomy-in-a-patient-with-pancreas-divisum-a-case-report
#20
Shimpei Otsuka, Teiichi Sugiura, Katsuhiko Uesaka
BACKGROUND: Pancreas-sparing total duodenectomy (PSTD) is an ideal recommended procedure for patients with multiple duodenal adenomas or early duodenal cancer. We herein report a rare but serious complication of PSTD. CASE PRESENTATION: A 20-year-old woman with duodenal adenocarcinoma underwent PSTD. On postoperative day one, she complained of severe abdominal pains. Her serum amylase and serum pancreatic amylase levels were extremely elevated (Amy, 1296 IU/L; P-Amy, 1273 IU/L)...
December 2016: Surgical Case Reports
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