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hemifacial spasm,botulinum toxin

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https://www.readbyqxmd.com/read/27906546/persistent-hemifacial-spasm-after-microvascular-decompression-a-risk-assessment-model
#1
Aalap Shah, Michael Horowitz
OBJECTIVE: Microvascular decompression (MVD) for hemifacial spasm (HFS) provides resolution of disabling symptoms such as eyelid twitching and muscle contractions of the entire hemiface. The primary aim of this study was to evaluate the predictive value of patient demographics and spasm characteristics on long-term outcomes, with or without intraoperative lateral spread response (LSR) as an additional variable in a risk assessment model. METHODS: A retrospective study was undertaken to evaluate the associations of pre-operative patient characteristics, as well as intraoperative LSR and need for a staged procedure on the presence of persistent or recurrent HFS at the time of hospital discharge and at follow-up...
December 1, 2016: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/27802860/hemifacial-spasm-in-a-patient-with-basilar-artery-dolichoectasia-caused-by-uncontrolled-hypertension
#2
Gordon S Crabtree, David Gish, David Goldberg
A 47-year-old male presented with a 2-year history of hemifacial spasm. Magnetic resonance imaging performed showed his tortuous basilar artery with nerve compression, and the patient was treated conservatively with botulinum toxin injections with complete resolution of symptoms. This rare disease was caused by his long history of hypertension, which led to his major basilar artery dolichoectasia.
2016: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/27761290/a-rare-cause-of-hemifacial-spasm-papillary-oncocytic-cystadenoma
#3
Ozan Erol, Erdinç Aydın
BACKGROUND: Hemifacial spasm is a sudden, involuntary and synchronous spasm of the facial muscles. The most frequent cause of this condition is compression of the facial nerves due to vascular pathologies. The most commonly used method of treatment is Botulinum toxin injection. However, the gold standard treatment is surgical treatment. CASE REPORT: A 64-year-old male patient with hemifacial spasms, which had occurred due to a rare parotid mass that had been surgically treated, is presented in this case...
September 2016: Balkan Medical Journal
https://www.readbyqxmd.com/read/27761118/sexual-well-being-in-patients-with-blepharospasm-spasmodic-torticollis-and-hemifacial-spasm-a-pilot-study
#4
Paola Perozzo, Adriana Salatino, Paolo Cerrato, Raffaella Ricci
Mood, anxiety, and other psychological symptoms are common in dystonic patients suffering from blepharospasm (BSP) and spasmodic torticollis (ST). Since sexual well-being is an important aspect of mental health, here, we investigated whether these patients may also experience a worsening of their sexual life. In particular, quality of sexual life was evaluated in patients suffering from BSP (N = 30), ST (N = 30), and in a control group of patient with Hemifacial spasm (HFS; N = 30), undergoing botulinum toxin type A therapy...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27606483/use-of-alleviating-maneuvers-for-periocular-facial-dystonias
#5
Caroline L S Kilduff, Edward J Casswell, Tahrina Salam, Dov Hersh, Santiago Ortiz-Perez, Daniel Ezra
Importance: Patients with benign essential blepharospasm or hemifacial spasm are known to use botulinum toxin injections and alleviating maneuvers to help control their symptoms. The clinical correlates between the use of botulinum toxin injections and the use of alleviating maneuvers are not well established. Objective: To determine whether the use of alleviating maneuvers for benign essential blepharospasm or hemifacial spasm correlates with disease severity or botulinum toxin treatment...
September 8, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27460515/efficacy-of-levetiracetam-in-primary-hemifacial-spasm
#6
Takeshi Kuroda, Yu Saito, Kazuhisa Fujita, Satoshi Yano, Seiichiro Ishigaki, Hirotaka Kato, Hidetomo Murakami, Kenjiro Ono
Hemifacial spasm (HFS) is a peripherally-induced movement disorder characterized by the involuntary, unilateral, intermittent, irregular, tonic or clonic contractions of muscles innervated by the ipsilateral facial nerve. Kindling-like hyperactivity of the facial nucleus induced by constant stimulation of compressing artery is considered as the predominant mechanism underlying the pathogenesis of HFS. As a treatment for HFS, microsurgical decompression and botulinum toxin injection have been shown to be highly successful...
July 22, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27439615/erratum-to-effectiveness-and-cost-effectiveness-of-a-patient-initiated-botulinum-toxin-treatment-model-for-blepharospasm-and-hemifacial-spasm-compared-to-standard-care-study-protocol-for-a-randomised-controlled-trial
#7
Sadie Wickwar, Hayley McBain, Stanton P Newman, Shashivadan P Hirani, Catherine Hurt, Nicola Dunlop, Chris Flood, Daniel G Ezra
No abstract text is available yet for this article.
2016: Trials
https://www.readbyqxmd.com/read/27431279/facial-asymmetry-in-patients-with-hemifacial-spasm-before-and-after-botulinum-toxin-a-treatment
#8
Libin Xiao, Yougui Pan, Xiaolong Zhang, Yong Hu, Li Cai, Zhiyu Nie, Lizhen Pan, Bing Li, Yijing He, Lingjing Jin
Botulinum toxin A (BoNT-A) injection is one of the most widely used methods for hemifacial spasm (HFS) with high efficacy in controlling spasm. However, it is still unknown if esthetic symmetry could be desired as the spasm was controlled by BoNT-A therapy. The purpose of this study is to clarify the facial asymmetric characteristics of HFS patients and if the asymmetry could be amended by BoNT-A injection in the abnormal side. In this prospective analysis, HFS patients were enrolled, who received hemifacial BoNT-A injection and completed follow-up at weeks 2-4...
July 18, 2016: Neurological Sciences
https://www.readbyqxmd.com/read/27255252/impact-of-botulinum-toxin-a-on-corneal-curvature-assessed-with-scheimpflug-and%C3%A2-placido-systems
#9
Teissy Osaki, Midori H Osaki, Tammy H Osaki, Flavio E Hirai, Nambi Nallasamy, Mauro Campos
PURPOSE: To evaluate the effect of eyelid spasm treatment with botulinum toxin-A (BTX-A) on corneal curvature assessed with Scheimpflug (Pentacam) and Placido (Atlas) systems. SETTING: Federal University of São Paulo, São Paulo, Brazil. DESIGN: Prospective interventional case series. METHODS: Patients with hemifacial spasm were evaluated. Steep keratometry (K) and corneal astigmatism (magnitudes and treatment-induced astigmatism) obtained with the Placido and Scheimpflug systems were evaluated before BTX-A application and after 15 days and 2, 3, and 4 months...
May 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27067535/increasing-the-area-and-varying-the-dosage-of-botulinum-toxin-a-injections-for-effective-treatment-of-hemifacial-spasm
#10
Won Joo Choe, Jin Kim
CONCLUSION: Wider-area botulinum toxin (BT) injection with the dosage depending on specific pathology is a promising approach for the treatment of hemifacial spasm (HFS), resulting in effective and long-lasting control of HFS with fewer side-effects. OBJECTIVE: The aim of this study was to develop a BT injection strategy that minimizes complications by considering the causes, duration, and electrophysiologic features of the disease, as well as the patient's age...
September 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/26984806/facial-spasms-but-not-hemifacial-spasm-a-case-report-and-review-of-literature
#11
Michael M McDowell, Xiao Zhu, Marion A Hughes, Raymond F Sekula
INTRODUCTION: Facial spasms represent a complicated array of neurological motor disorders with unique diagnostic and treatment algorithms. Due to the rarity of many of these disorders in the pediatric population, special care must be taken in identifying subtle differences in presentation of these disorders. METHODS: We present a case of a 3-year-old boy diagnosed with a brainstem ganglioglioma, Chiari 1 malformation, and a 2-year history of left-sided facial spasms...
September 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/26961367/effectiveness-and-cost-effectiveness-of-a-patient-initiated-botulinum-toxin-treatment-model-for-blepharospasm-and-hemifacial-spasm-compared-to-standard-care-study-protocol-for-a-randomised-controlled-trial
#12
Sadie Wickwar, Hayley McBain, Stanton P Newman, Shashivadan P Hirani, Catherine Hurt, Nicola Dunlop, Chris Flood, Daniel G Ezra
BACKGROUND: Blepharospasm and hemifacial spasm are debilitating conditions that significantly impact on patient quality of life. Cyclical treatment with botulinum toxin injections offers temporary relief, but the duration of treatment efficacy is variable. The standard model of patient care defines routine fixed-time based scheduled treatment cycles which may lead to unnecessarily frequent treatment for some patients and experience of distressing symptoms in others, if symptoms return before the scheduled follow-up period...
2016: Trials
https://www.readbyqxmd.com/read/26959061/conversion-ratio-between-botox%C3%A2-dysport%C3%A2-and-xeomin%C3%A2-in-clinical-practice
#13
REVIEW
Francesco Scaglione
Botulinum neurotoxin has revolutionized the treatment of spasticity and is now administered worldwide. There are currently three leading botulinum neurotoxin type A products available in the Western Hemisphere: onabotulinum toxin-A (ONA) Botox(®), abobotulinum toxin-A (ABO), Dysport(®), and incobotulinum toxin A (INCO, Xeomin(®)). Although the efficacies are similar, there is an intense debate regarding the comparability of various preparations. Here we will address the clinical issues of potency and conversion ratios, as well as safety issues such as toxin spread and immunogenicity, to provide guidance for BoNT-A use in clinical practice...
March 2016: Toxins
https://www.readbyqxmd.com/read/26917963/considerations-on-patient-related-outcomes-with-the-use-of-botulinum-toxins-is-switching-products-safe
#14
REVIEW
Avram Fraint, Padmaja Vittal, Cynthia Comella
INTRODUCTION: Botulinum toxin (BoNT) is the treatment of choice for many neurologic movement disorders, including blepharospasm, hemifacial spasm, and cervical dystonia. There are two serotypes approved for use by the US Food and Drug Administration: three brands of serotype A and one of serotype B. Many attempts have been made at establishing dose conversion ratios between brands and serotypes. This review focuses on the existing data comparing different formulations of the same BoNT serotypes as well as that comparing different serotypes with one another...
2016: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/26866500/botulinum-toxin-treatment-of-blepharospasm-orofacial-oromandibular-dystonia-and-hemifacial-spasm
#15
Barbara Illowsky Karp, Katharine Alter
Blepharospasm is a focal dystonia characterized by involuntary, repetitive eye closure. Orofacial and oromandibular dystonia describe involuntary dystonic movements of orofacial and oromandibular musculature. Hemifacial spasm is characterized by repetitive synchronous contraction of facial nerve innervated muscles on one side of the face. In this article, the clinical presentation, epidemiology, and approaches to treatment are reviewed. Technical aspects of using botulinum toxin for treatment and reported outcomes are discussed...
February 2016: Seminars in Neurology
https://www.readbyqxmd.com/read/26817183/the-difference-of-treatment-results-between-botulinum-toxin-a-split-injection-sites-and-botulinum-toxin-a-non-split-injection-sites-for-hemifacial-spasm
#16
RANDOMIZED CONTROLLED TRIAL
Anuwat Prutthipongsit, Nipat Aui-aree
OBJECTIVE: To compare hemifacial spasm treatment results between Botulinum toxin A split injection sites and Botulinum toxin A non-split injection sites. MATERIAL AND METHOD: Thirty-one hemifacial spasm patients were randomly assigned into the non-split injection sites group (injecting Botulinum toxin A to the zygomaticus major and risorius each) or split injection sites group with the same amount of Botulinum toxin A as the first method (injection Botulinum toxin A to the zygomaticus major and minor and risorius two injections each) The main outcomes are onset of improvement and effective duration of treatment...
November 2015: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/26780946/botulinum-toxin-and-muscle-atrophy-a-wanted-or-unwanted-effect
#17
Paul D Durand, Rafael A Couto, Raymond Isakov, Donald B Yoo, Babak Azizzadeh, Bahman Guyuron, James E Zins
While the facial rejuvenating effect of botulinum toxin type A is well known and widespread, its use in body and facial contouring is less common. We first describe its use for deliberate muscle volume reduction, and then document instances of unanticipated and undesirable muscle atrophy. Finally, we investigate the potential long-term adverse effects of botulinum toxin-induced muscle atrophy. Although the use of botulinum toxin type A in the cosmetic patient has been extensively studied, there are several questions yet to be addressed...
April 2016: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/26774197/-painful-tic-convulsif-case-series-and-literature-review
#18
Rogelio Revuelta-Gutiérrez, Héctor Sebastián Velasco-Torres, Lourdes Olivia Vales Hidalgo, Jaime Jesús Martínez-Anda
BACKGROUND: The coexistence of hemifacial spasm and trigeminal neuralgia, a clinical entity known as painful tic convulsive, was first described in 1910. It is an uncommon condition that is worthy of interest in neurosurgical practice, because of its common pathophysiology mechanism: Neuro-vascular compression in most of the cases. OBJECTIVE: To present 2 cases of painful tic convulsive that received treatment at our institution, and to give a brief review of the existing literature related to this...
January 13, 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/26619386/differences-in-corneal-parameters-between-affected-and-normal-contralateral-eyes-in-patients-with-hemifacial-spasm-treated-with-botulinum-toxin-a-outcomes-during-one-complete-treatment-cycle
#19
COMPARATIVE STUDY
Teissy Osaki, Midori H Osaki, Tammy H Osaki, Flavio E Hirai, Mauro Campos
PURPOSE: To investigate possible temporary differences in corneal topographic parameters between affected and normal eyes in patients with hemifacial spasm (HFS) treated with botulinum toxin-A (BTX-A), over the course of 1 treatment cycle. METHODS: This prospective study evaluated corneal topographic differences between affected and normal contralateral eyes during a 4-month period in patients with HFS treated with BTX-A (the duration of action of BTX-A for HFS ranges from 2 to 4 months)...
February 2016: Cornea
https://www.readbyqxmd.com/read/26541432/influence-of-involuntary-eyelid-spasms-on-corneal-topographic-and-eyelid-morphometric-changes-in-patients-with-hemifacial-spasm
#20
Teissy Osaki, Midori H Osaki, Tammy H Osaki, Flavio E Hirai, Nambi Nallasamy, Mauro Campos
BACKGROUND/AIMS: In patients with hemifacial spasm (HFS), treatment relieves eyelid spasms on the affected side, thus changes in corneal topography and eyelid morphometry may be observed after treatment. We aimed to evaluate these parameters during a 4-month period in patients with HFS treated with botulinum toxin A (BTX-A). METHODS: This prospective study evaluated eyelid morphometric and corneal topographic changes in patients with HFS before onabotulinum toxin A application, and after 15 days and 2, 3 and 4 months...
November 5, 2015: British Journal of Ophthalmology
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