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hemifacial spasm,botulinum toxin

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https://www.readbyqxmd.com/read/28226076/treatment-of-hemifacial-spasm-with-botulinum-toxin-type-a-effective-long-lasting-and-well-tolerated
#1
Jean Pierre Mette Batisti, Alais Daiane Fadini Kleinfelder, Natália Bassalobre Galli, Adriana Moro, Renato Puppi Munhoz, Hélio Afonso Ghizoni Teive
Objective: To evaluate the long-term effect of botulinum toxin type A (BTX-A) in the treatment of HFS. Methods: A retrospective analysis of patients treated at the Movement Disorders Outpatient Clinic in the Neurology Service, Hospital de Clínicas, Federal University of Paraná, Curitiba, from 2009 to 2013 was carried out. A total of 550 BTX-A injections were administered to 100 HFS patients. Results: Mean duration of improvement following each injection session was 3...
February 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28223858/the-therapeutic-usage-of-botulinum-toxin-botox-in-non-cosmetic-head-and-neck-conditions-an-evidence-based-review
#2
REVIEW
Kamran Habib Awan
Botulinum toxin (Botox) is an exotoxin produced from Clostridium botulinum. It blocks the release of acetylcholine from the cholinergic nerve end plates resulting in inactivity of the muscles or glands innervated. The efficacy of Botox in facial aesthetics is well established; however, recent literature has highlighted its utilization in multiple non-cosmetic medical and surgical conditions. The present article reviews the current evidence pertaining to Botox use in the non-cosmetic head and neck conditions...
January 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28186450/an-investigation-into-quality-of-life-improvement-in-patients-undergoing-microvascular-decompression-for-hemifacial-spasm
#3
Jesse D Lawrence, Andrew M Frederickson, Yue-Fang Chang, Patricia M Weiss, Peter C Gerszten, Raymond F Sekula
OBJECTIVE Hemifacial spasm (HFS) is a movement disorder characterized by involuntary spasms of the facial muscles, and it can negatively impact quality of life (QOL). This retrospective study and systematic review with meta-analysis was conducted to investigate the QOL in patients with HFS following intervention with microvascular decompression (MVD) and botulinum toxin (BT). METHODS In the retrospective analysis, a QOL questionnaire was administered to all patients undergoing MVD performed by a single surgeon...
February 10, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28114700/-botulinum-toxin-new-developments-in-ophthalmology
#4
B Wabbels
Botulinum toxin is recognised as the gold standard for the treatment of essential blepharospasm and hemifacial spasm, which is similar in effect in synkinesis after facial nerve palsy. The injection intervals can be adjusted according to the patients' needs and be shortened for up to six weeks in cases of eyelid cramping. Newer indications for the use of botulinum toxin in ophthalmology include eyelid retraction in Graves' disease, induction of protective ptosis and treatment of crocodile tears syndrome after facial nerve palsy...
January 23, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28088801/natural-history-of-untreated-hemifacial-spasm-a-study-of-104-consecutive-patients-over-5-years
#5
Jeong-A Lee, Kyung-Hee Kim, Kwan Park
BACKGROUND: The natural history without treatment of a large series of hemifacial spasm (HFS) patients has not been well-documented. OBJECTIVE: The purpose of this study was to characterize the natural history and clinical outcome in patients with HFS. METHODS: The initial visits of all 2,155 patients and the diagnosis of HFS took place between 2001 and 2010. In 1,775 of the patients, compressing vessels were identified on magnetic resonance imaging...
2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28050326/use-of-botulinum-neurotoxin-in-ophthalmology
#6
REVIEW
Emel Başar, Ceyhun Arıcı
Botulinum neurotoxin (BoNT) is the first biological toxin used in the treatment of ophthalmic diseases and to decrease skin wrinkles as an aesthetic agent. When used appropriately, it weakens the force of muscular contraction and/or inhibits glandular secretion. The most common areas for botulinum toxin treatment are the upper face, including the glabella, forehead, brows, and lateral canthal lines, or crow's feet. By relaxing the muscles causing wrinkles, non-permanent results may be achieved with its use...
December 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27906546/persistent-hemifacial-spasm-after-microvascular-decompression-a-risk-assessment-model
#7
Aalap Shah, Michael Horowitz
OBJECTIVE: Microvascular decompression (MVD) for hemifacial spasm (HFS) provides resolution of disabling symptoms such as eyelid twitching and muscle contractions of the entire hemiface. The primary aim of this study was to evaluate the predictive value of patient demographics and spasm characteristics on long-term outcomes, with or without intraoperative lateral spread response (LSR) as an additional variable in a risk assessment model. METHODS: A retrospective study was undertaken to evaluate the associations of pre-operative patient characteristics, as well as intraoperative LSR and need for a staged procedure on the presence of persistent or recurrent HFS at the time of hospital discharge and at follow-up...
December 1, 2016: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/27802860/hemifacial-spasm-in-a-patient-with-basilar-artery-dolichoectasia-caused-by-uncontrolled-hypertension
#8
Gordon S Crabtree, David Gish, David Goldberg
A 47-year-old male presented with a 2-year history of hemifacial spasm. Magnetic resonance imaging performed showed his tortuous basilar artery with nerve compression, and the patient was treated conservatively with botulinum toxin injections with complete resolution of symptoms. This rare disease was caused by his long history of hypertension, which led to his major basilar artery dolichoectasia.
2016: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/27761290/a-rare-cause-of-hemifacial-spasm-papillary-oncocytic-cystadenoma
#9
Ozan Erol, Erdinç Aydın
BACKGROUND: Hemifacial spasm is a sudden, involuntary and synchronous spasm of the facial muscles. The most frequent cause of this condition is compression of the facial nerves due to vascular pathologies. The most commonly used method of treatment is Botulinum toxin injection. However, the gold standard treatment is surgical treatment. CASE REPORT: A 64-year-old male patient with hemifacial spasms, which had occurred due to a rare parotid mass that had been surgically treated, is presented in this case...
September 2016: Balkan Medical Journal
https://www.readbyqxmd.com/read/27761118/sexual-well-being-in-patients-with-blepharospasm-spasmodic-torticollis-and-hemifacial-spasm-a-pilot-study
#10
Paola Perozzo, Adriana Salatino, Paolo Cerrato, Raffaella Ricci
Mood, anxiety, and other psychological symptoms are common in dystonic patients suffering from blepharospasm (BSP) and spasmodic torticollis (ST). Since sexual well-being is an important aspect of mental health, here, we investigated whether these patients may also experience a worsening of their sexual life. In particular, quality of sexual life was evaluated in patients suffering from BSP (N = 30), ST (N = 30), and in a control group of patient with Hemifacial spasm (HFS; N = 30), undergoing botulinum toxin type A therapy...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27606483/use-of-alleviating-maneuvers-for-periocular-facial-dystonias
#11
Caroline L S Kilduff, Edward J Casswell, Tahrina Salam, Dov Hersh, Santiago Ortiz-Perez, Daniel Ezra
Importance: Patients with benign essential blepharospasm or hemifacial spasm are known to use botulinum toxin injections and alleviating maneuvers to help control their symptoms. The clinical correlates between the use of botulinum toxin injections and the use of alleviating maneuvers are not well established. Objective: To determine whether the use of alleviating maneuvers for benign essential blepharospasm or hemifacial spasm correlates with disease severity or botulinum toxin treatment...
November 1, 2016: JAMA Ophthalmology
https://www.readbyqxmd.com/read/27460515/efficacy-of-levetiracetam-in-primary-hemifacial-spasm
#12
REVIEW
Takeshi Kuroda, Yu Saito, Kazuhisa Fujita, Satoshi Yano, Seiichiro Ishigaki, Hirotaka Kato, Hidetomo Murakami, Kenjiro Ono
Hemifacial spasm (HFS) is a peripherally-induced movement disorder characterized by the involuntary, unilateral, intermittent, irregular, tonic or clonic contractions of muscles innervated by the ipsilateral facial nerve. Kindling-like hyperactivity of the facial nucleus induced by constant stimulation of compressing artery is considered as the predominant mechanism underlying the pathogenesis of HFS. As a treatment for HFS, microsurgical decompression and botulinum toxin injection have been shown to be highly successful...
December 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/27439615/erratum-to-effectiveness-and-cost-effectiveness-of-a-patient-initiated-botulinum-toxin-treatment-model-for-blepharospasm-and-hemifacial-spasm-compared-to-standard-care-study-protocol-for-a-randomised-controlled-trial
#13
Sadie Wickwar, Hayley McBain, Stanton P Newman, Shashivadan P Hirani, Catherine Hurt, Nicola Dunlop, Chris Flood, Daniel G Ezra
No abstract text is available yet for this article.
July 20, 2016: Trials
https://www.readbyqxmd.com/read/27431279/facial-asymmetry-in-patients-with-hemifacial-spasm-before-and-after-botulinum-toxin-a-treatment
#14
Libin Xiao, Yougui Pan, Xiaolong Zhang, Yong Hu, Li Cai, Zhiyu Nie, Lizhen Pan, Bing Li, Yijing He, Lingjing Jin
Botulinum toxin A (BoNT-A) injection is one of the most widely used methods for hemifacial spasm (HFS) with high efficacy in controlling spasm. However, it is still unknown if esthetic symmetry could be desired as the spasm was controlled by BoNT-A therapy. The purpose of this study is to clarify the facial asymmetric characteristics of HFS patients and if the asymmetry could be amended by BoNT-A injection in the abnormal side. In this prospective analysis, HFS patients were enrolled, who received hemifacial BoNT-A injection and completed follow-up at weeks 2-4...
November 2016: Neurological Sciences
https://www.readbyqxmd.com/read/27255252/impact-of-botulinum-toxin-a-on-corneal-curvature-assessed-with-scheimpflug-and%C3%A2-placido-systems
#15
Teissy Osaki, Midori H Osaki, Tammy H Osaki, Flavio E Hirai, Nambi Nallasamy, Mauro Campos
PURPOSE: To evaluate the effect of eyelid spasm treatment with botulinum toxin-A (BTX-A) on corneal curvature assessed with Scheimpflug (Pentacam) and Placido (Atlas) systems. SETTING: Federal University of São Paulo, São Paulo, Brazil. DESIGN: Prospective interventional case series. METHODS: Patients with hemifacial spasm were evaluated. Steep keratometry (K) and corneal astigmatism (magnitudes and treatment-induced astigmatism) obtained with the Placido and Scheimpflug systems were evaluated before BTX-A application and after 15 days and 2, 3, and 4 months...
May 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27067535/increasing-the-area-and-varying-the-dosage-of-botulinum-toxin-a-injections-for-effective-treatment-of-hemifacial-spasm
#16
Won Joo Choe, Jin Kim
CONCLUSION: Wider-area botulinum toxin (BT) injection with the dosage depending on specific pathology is a promising approach for the treatment of hemifacial spasm (HFS), resulting in effective and long-lasting control of HFS with fewer side-effects. OBJECTIVE: The aim of this study was to develop a BT injection strategy that minimizes complications by considering the causes, duration, and electrophysiologic features of the disease, as well as the patient's age...
September 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/26984806/facial-spasms-but-not-hemifacial-spasm-a-case-report-and-review-of-literature
#17
Michael M McDowell, Xiao Zhu, Marion A Hughes, Raymond F Sekula
INTRODUCTION: Facial spasms represent a complicated array of neurological motor disorders with unique diagnostic and treatment algorithms. Due to the rarity of many of these disorders in the pediatric population, special care must be taken in identifying subtle differences in presentation of these disorders. METHODS: We present a case of a 3-year-old boy diagnosed with a brainstem ganglioglioma, Chiari 1 malformation, and a 2-year history of left-sided facial spasms...
September 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/26961367/effectiveness-and-cost-effectiveness-of-a-patient-initiated-botulinum-toxin-treatment-model-for-blepharospasm-and-hemifacial-spasm-compared-to-standard-care-study-protocol-for-a-randomised-controlled-trial
#18
RANDOMIZED CONTROLLED TRIAL
Sadie Wickwar, Hayley McBain, Stanton P Newman, Shashivadan P Hirani, Catherine Hurt, Nicola Dunlop, Chris Flood, Daniel G Ezra
BACKGROUND: Blepharospasm and hemifacial spasm are debilitating conditions that significantly impact on patient quality of life. Cyclical treatment with botulinum toxin injections offers temporary relief, but the duration of treatment efficacy is variable. The standard model of patient care defines routine fixed-time based scheduled treatment cycles which may lead to unnecessarily frequent treatment for some patients and experience of distressing symptoms in others, if symptoms return before the scheduled follow-up period...
March 9, 2016: Trials
https://www.readbyqxmd.com/read/26959061/conversion-ratio-between-botox%C3%A2-dysport%C3%A2-and-xeomin%C3%A2-in-clinical-practice
#19
REVIEW
Francesco Scaglione
Botulinum neurotoxin has revolutionized the treatment of spasticity and is now administered worldwide. There are currently three leading botulinum neurotoxin type A products available in the Western Hemisphere: onabotulinum toxin-A (ONA) Botox(®), abobotulinum toxin-A (ABO), Dysport(®), and incobotulinum toxin A (INCO, Xeomin(®)). Although the efficacies are similar, there is an intense debate regarding the comparability of various preparations. Here we will address the clinical issues of potency and conversion ratios, as well as safety issues such as toxin spread and immunogenicity, to provide guidance for BoNT-A use in clinical practice...
March 4, 2016: Toxins
https://www.readbyqxmd.com/read/26917963/considerations-on-patient-related-outcomes-with-the-use-of-botulinum-toxins-is-switching-products-safe
#20
REVIEW
Avram Fraint, Padmaja Vittal, Cynthia Comella
INTRODUCTION: Botulinum toxin (BoNT) is the treatment of choice for many neurologic movement disorders, including blepharospasm, hemifacial spasm, and cervical dystonia. There are two serotypes approved for use by the US Food and Drug Administration: three brands of serotype A and one of serotype B. Many attempts have been made at establishing dose conversion ratios between brands and serotypes. This review focuses on the existing data comparing different formulations of the same BoNT serotypes as well as that comparing different serotypes with one another...
2016: Therapeutics and Clinical Risk Management
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