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https://www.readbyqxmd.com/read/29161707/a-novel-animal-model-simulating-the-beginning-of-combat-exposure
#1
Dongsoo Kim, Chang Yul Kim, Hyojin Koo, Yong Heo, Kicheol Cheon
OBJECTIVE: Predator stress, social defeat stress, and fear conditioning animal models have been applied to investigate combat-related posttraumatic stress disorder (PTSD). However, no animal model psychopharmacological studies have investigated prevention of somatization of increased mental stress and fatigue at the beginning of combat exposure. This study utilized a novel animal model simulating the beginning of combat exposure that aided specification of a set of biomarkers. METHODS: Psychological stress was induced by both inescapable electric foot shock and noise stimuli...
November 22, 2017: Neuroimmunomodulation
https://www.readbyqxmd.com/read/29161523/does-acute-propranolol-treatment-prevent-posttraumatic-stress-disorder-anxiety-and-depression-in-children-with-burns
#2
Laura Rosenberg, Marta Rosenberg, Sherri Sharp, Christopher R Thomas, Helen F Humphries, Charles E Holzer, David N Herndon, Walter J Meyer
OBJECTIVE: This study examined whether acute propranolol treatment prevented posttraumatic stress disorder (PTSD), anxiety, and depression in children hospitalized in the pediatric intensive care unit for large burns. We hypothesized that the prevalence of PTSD, anxiety, and depression would be significantly less in the propranolol than nonpropranolol groups. METHODS: Children who had previously participated in a randomized controlled clinical trial of acute propranolol and nonpropranolol controls were invited to participate in long-term follow-up interviews...
November 21, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29161451/combat-ptsd-and-smoking-trajectory-in-a-cohort-of-male-australian-army-vietnam-veterans
#3
Brian I O'Toole, Robyn Kirk, Renée Bittoun, Stanley V Catts
Background: Whether trauma exposure itself or consequent posttraumatic stress disorder (PTSD) is primarily responsible for smoking and failure to quit remains unclear. Methods: A cohort of male Australian Vietnam veterans (N = 388) was interviewed twice, 22 and 36 years after their return to Australia using standardized psychiatric diagnostic and health interviews and assessment of combat exposure. The smoking trajectory over time revealed a spectrum of outcomes (never smoked, early quitters, late quitters, continuing smokers)...
November 17, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29161156/sense-of-community-among-female-residents-of-a-trauma-informed-sober-living-home
#4
Katie M Edwards, Ellen E Haynes, Kelly M Palmer, Sharon Murphy
BACKGROUND: Substance use disorders (SUDs) and domestic and/or sexual violence (DSV) co-occur at high rates. Although some studies have examined sober living homes (SLHs), no research to date has evaluated SLHs specifically designed for women with histories of SUDS and DSV. OBJECTIVE: The purpose of this article is to present data from an exploratory analysis of the association between sense of community (SOC) and mental health symptoms within a unique trauma-informed and gender-responsive SLH (i...
November 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/29160613/posttraumatic-stress-disorder-and-its-effects-on-pregnancy-and-mothering
#5
(no author information available yet)
No abstract text is available yet for this article.
November 21, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29160560/a-functional-near-infrared-spectroscopy-study-of-trauma-related-auditory-and-olfactory-cues-posttraumatic-stress-disorder-or-combat-experience
#6
Michael A Gramlich, Sandra M Neer, Deborah C Beidel, Corey J Bohil, Clint A Bowers
The prevalence of posttraumatic stress disorder (PTSD) among U.S. veterans deployed to Iraq or Afghanistan necessitates the need for comprehensive assessment and treatment strategies. This study investigated the utility of a combat-related PTSD symptom provocation paradigm to elicit unique neurological responses across three groups: combat veterans with PTSD, combat veterans without PTSD, and nonmilitary participants without PTSD. Using functional near-infrared spectroscopy (fNIRS) the results indicated that combat veterans with PTSD demonstrated significant activation to a trauma-related sound compared with nonmilitary personnel, channel 14: d = 1...
November 21, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29160557/the-complex-trauma-inventory-a-self-report-measure-of-posttraumatic-stress-disorder-and-complex-posttraumatic-stress-disorder
#7
Justin M Litvin, Patricia L Kaminski, Shelley A Riggs
The work group revising the criteria for trauma-related disorders in the International Classification of Diseases (ICD-11) made several changes. Specifically, they simplified the criteria for posttraumatic stress disorder (PTSD) and added a new trauma disorder called complex PTSD (CPTSD). These proposed changes to taxonomy require new instruments to assess these novel constructs. We developed a measure of PTSD and CPTSD (the Complex Trauma Inventory; CTI) according to the proposed domains, creating several items to assess each domain...
November 21, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29160555/the-effect-of-sleep-disorders-sedating-medications-and-depression-on-cognitive-processing-therapy-outcomes-a-fuzzy-set-qualitative-comparative-analysis
#8
Patricia L Haynes, Sarah E Emert, Dana Epstein, Suzanne Perkins, Sairam Parthasarathy, James Wilcox
Cognitive processing therapy (CPT) for posttraumatic stress disorder (PTSD) is an effortful process requiring engagement in cognitive restructuring. Sleep disorders may lead to avoidance of effortful tasks and cognitive performance deficits. We explored whether sleep disorders, as assessed by polysomnography, were consistently associated with treatment response in combination with other factors. This study included 32 U.S. veterans who were examined both before and after CPT for combat-related PTSD. We employed a novel, case-comparative technique, fuzzy set qualitative comparative analysis (fsQCA), to identify combinations of fuzzy and crisp factors (recipes) that achieve a clinically significant outcome...
November 21, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29157934/posttraumatic-stress-disorder-onset-and-inflammatory-and-endothelial-function-biomarkers-in-women
#9
Jennifer A Sumner, Qixuan Chen, Andrea L Roberts, Ashley Winning, Eric B Rimm, Paola Gilsanz, M Maria Glymour, Shelley S Tworoger, Karestan C Koenen, Laura D Kubzansky
BACKGROUND: Research has linked posttraumatic stress disorder (PTSD) with higher circulating levels of inflammatory and endothelial function (EF) biomarkers, and effects may be bidirectional. We conducted the first investigation of new-onset PTSD and changes in inflammatory and EF biomarkers. METHODS: Data were from women in the Nurses' Health Study II. Biomarkers obtained at two blood draws, 10-16 years apart, included C-reactive protein (CRP), tumor necrosis factor-alpha receptor-II (TNFRII), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1)...
November 17, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29157796/neuropeptide-s-in-the-basolateral-amygdala-mediates-an-adaptive-behavioral-stress-response-in-a-rat-model-of-posttraumatic-stress-disorder-by-increasing-the-expression-of-bdnf-and-the-neuropeptide-yy1-receptor
#10
Cohen Hagit, Vainer Ella, Zeev Kaplan, Zohar Joseph, Mathé A Aleksander
Neuropeptide S (NPS) is a regulatory peptide that has anxiolytic and arousal-promoting effects in rodents. We used an animal model of posttraumatic stress disorder (PTSD) to assess long-term behavioral effects of a single dose of NPS, microinjected into the basolateral amygdala (BLA) 1h following exposure to predator-scent stress (PSS). To elucidate the molecular mechanism by which NPS attenuates behavioral stress responses, expression levels of neuropeptide Y (NPY), NPY-Y1 receptor (NPY-Y1R), and brain-derived neurotrophic factor (BDNF) were evaluated in the hippocampus...
November 17, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29157504/domestic-minor-sex-trafficking
#11
REVIEW
Amy Goldberg, Jessica Moore
Commercial sexual exploitation of children and child sex trafficking is a major public health issue globally. Domestic minor sex trafficking has become increasingly recognized within the United States. Sexually exploited minors are commonly identified as having psychosocial risk factors, including histories of abuse or neglect, running away, substance use or abuse, and involvement with child protective services. Youth also suffer a variety of physical and mental health consequences, including posttraumatic stress disorder, depression, anxiety, and suicidality...
January 2018: Child and Adolescent Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/29156296/associations-between-severity-of-anxiety-and-clinical-and-biological-features-of-major-affective-disorders
#12
Fernanda Liboni Cavicchioli, Michael Maes, Chutima Roomruangwong, Kamila Landucci Bonifacio, Decio Sabbatini Barbosa, George Anderson, Heber Odebrecht Vargas, Sandra Odebrecht Vargas Nunes
Patients with major affective disorders (MAFD) with comorbid anxiety show a greater functional impairment than those without anxiety. The aim of this study is to delineate the associations between severity of anxiety in MAFD, namely bipolar disorder (BD) and major depression (MDD), and MAFD characteristics and serum high-density lipoprotein (HDL)-cholesterol levels. Recruited were 82 participants with anxiety disoders and 83 without anxiety disoders, including 101 MAFD patients and 51 healthy controls. We used the Hamilton Anxiety Rating Scale (HAM-A) to measure severity of anxiety and made the diagnoses of posttraumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), panic disorder (PD), generalized anxiety disorder (GAD) and phobias...
November 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29154809/facilitated-acquisition-of-the-classically-conditioned-eyeblink-response-in-active-duty-military-expressing-posttraumatic-stress-disorder-symptoms
#13
Justin D Handy, Pelin Avcu, Nora Ko, Alejandro Ortiz, Michael J Doria, Richard J Servatius
OBJECTIVE: Learning diathesis models underscore the role of hyper-conditioning in the development of PTSD following trauma exposure. Eyeblink classical conditioning is one method of examining associative learning biases independent of fear and threat produced by trauma. Facilitated learning is apparent in individuals self-expressing PTSD symptoms, as well as behaviorally inhibited (BI) temperament, a vulnerability factor for PTSD. Here, we examine eyeblink conditioning in active duty military personnel and relate learning with PTSD symptomology...
November 14, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29154599/negative-outcomes-after-morally-injurious-experiences-a-replication-and-extension
#14
Steven Lloyd Lancaster
OBJECTIVE: The current study replicates and extends a model of the relationship between morally injurious experiences, moral emotions, and posttraumatic stress disorder (PTSD; Jordan, Eisen, Bolton, Nash, & Litz, 2017). The current study builds on this earlier work by including broader measures of moral emotions and by including an assessment of symptoms of depression. METHOD: An online survey, distributed using crowdsourcing software, was completed by 161 military veterans...
November 20, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29154597/interactive-effects-of-insomnia-symptoms-and-trauma-exposure-on-ptsd-examination-of-symptom-specificity
#15
Rebecca C Cox, W Alex McIntyre, Bunmi O Olatunji
OBJECTIVE: Although symptoms of posttraumatic stress disorder (PTSD) are common following exposure to a traumatic event, most people who experience trauma do not develop PTSD. Thus, the identification of risk factors that may interact with trauma exposure to confer vulnerability for the development of PTSD may highlight important targets for prevention and treatment. Recent research suggests that sleep disturbance amplifies the effect of maladaptive emotional processes on PTSD symptom severity...
November 20, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29154596/the-moderating-role-of-trauma-type-on-the-relationship-between-event-centrality-of-the-traumatic-experience-and-mental-health-outcomes
#16
Rachel Wamser-Nanney, Kathryn H Howell, Laura E Schwartz, Amanda J Hasselle
OBJECTIVE: Event centrality, or the extent to which traumatic events are perceived to be integral to one's life, has been found to be predictive of trauma-related symptoms, such as posttraumatic stress disorder (PTSD) and depression. Less research has been devoted to whether event centrality is related to adaptive outcomes, such as posttraumatic growth (PTG) and resiliency, and psychological well-being (PWB) has not been investigated. Given the unique circumstances of different types of traumas, the relationship between event centrality and posttrauma functioning may differ by the type of trauma experienced...
November 20, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29154594/morally-injurious-events-and-psychological-distress-among-veterans-examining-the-mediating-role-of-religious-and-spiritual-struggles
#17
Wyatt R Evans, Melinda A Stanley, Terri L Barrera, Julie J Exline, Kenneth I Pargament, Ellen J Teng
OBJECTIVE: Potentially morally injurious events (PMIEs)-violations (perpetrated or witnessed) of one's deeply held beliefs or values-have been associated with several forms of psychological distress. The values violated by PMIEs are often influenced by one's religion/spirituality (r/s). Struggles with one's r/s beliefs and/or practices may also contribute to elevated psychological distress. To further develop a framework for understanding and treating the sequelae of PMIE exposure, we examined the role of r/s struggles in the relation between PMIE exposure and psychological distress...
November 20, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29154592/college-females-with-maltreatment-histories-have-atypical-autonomic-regulation-and-poor-psychological-wellbeing
#18
Lourdes P Dale, Samia K Shaikh, Laura C Fasciano, Vanessa D Watorek, Keri J Heilman, Stephen W Porges
OBJECTIVES: This study uniquely examined the impact of maltreatment (without a diagnosis of posttraumatic stress disorder [PTSD]) on physiological responses to a physical and an emotional stressor. The study sample was composed exclusively of women, because men may differ in maltreatment experience and neural regulation of physiological reactivity. METHOD: Participants were 60 female college students. A significant proportion of the participants reported experiencing childhood maltreatment without a history of PTSD...
November 20, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29154591/the-impact-of-comorbid-diagnoses-on-the-course-of-posttraumatic-stress-disorder-symptoms-in-residents-of-battered-women-s-shelters
#19
Katherine M Fedele, Nicole L Johnson, Jennifer C Caldwell, Yuliya Shteynberg, Sarah E Sanders, Samantha C Holmes, Dawn M Johnson
OBJECTIVE: The current investigation sought to explore the impact of the comorbidities of substance use disorder (SUD), major depressive disorder (MDD), and borderline personality disorder (BPD) on the trajectory of intimate partner violence (IPV)-related posttraumatic stress disorder (PTSD) symptoms across a 6-month follow-up period in IPV survivors who seek shelter. Research has found significant comorbidity of SUD, MDD, and BPD with PTSD (see Green et al., 2006; Kessler, Sonnega, Bromet, Hughes, & Nelson, 1995; Pagura et al...
November 20, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29152674/progress-and-promise-for-the-mdma-drug-development-program
#20
REVIEW
Allison A Feduccia, Julie Holland, Michael C Mithoefer
Pharmacotherapy is often used to target symptoms of posttraumatic stress disorder (PTSD), but does not provide definitive treatment, and side effects of daily medication are often problematic. Trauma-focused psychotherapies are more likely than drug treatment to achieve PTSD remission, but have high dropout rates and ineffective for a large percentage of patients. Therefore, research into drugs that might increase the effectiveness of psychotherapy is a logical avenue of investigation. The most promising drug studied as a catalyst to psychotherapy for PTSD thus far is 3,4-methylenedioxymethamphetamine (MDMA), commonly known as the recreational drug "Ecstasy...
November 20, 2017: Psychopharmacology
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