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Posttraumatic stress disorder

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https://www.readbyqxmd.com/read/28926486/comorbid-posttraumatic-stress-disorder-and-traumatic-brain-injury-generalization-of-prolonged-exposure-ptsd-treatment-outcomes-to-postconcussive-symptoms-cognition-and-self-efficacy-in-veterans-and-active-duty-service-members
#1
Gregory K Wolf, Gregory J Mauntel, Tracy Kretzmer, Eric Crawford, Christina Thors, Thad Q Strom, Rodney D Vanderploeg
OBJECTIVES: To examine (a) generalization of the effectiveness of prolonged exposure (PE) therapy for posttraumatic stress disorder (PTSD) in improving postconcussive symptoms (PCSs) and other outcomes in military service members and Veterans (VA) with histories of mild to severe traumatic brain injury (TBI), and (b) factors associated with PCS reduction. SETTING: VA polytrauma medical center. PARTICIPANTS: Consecutive referrals for PTSD treatment of Active Duty (n = 17) or Veterans (n = 27) diagnosed with PTSD and TBI (N = 44)...
September 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28925716/differential-neural-activation-when-voluntarily-regulating-emotions-in-service-members-with-chronic-mild-traumatic-brain-injury
#2
Michael N Dretsch, Thomas A Daniel, Adam M Goodman, Jeffrey S Katz, Thomas Denney, Gopikrishna Deshpande, Jennifer L Robinson
The objective of this study was to characterize the functional activation of the neural correlates of voluntary regulation of emotion in soldiers both with and without chronic mild traumatic brain injury (mTBI). Using functional magnetic resonance imaging (fMRI) and a battery of cognitive and psychological health measures, we assessed differences between active-duty U.S. soldiers with chronic mTBI (n = 37) and without (Controls, n = 35). Participants were instructed to maintain (passively view), enhance, and suppress emotions associated with negative and neutral visual stimuli...
September 19, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28925389/ptsd-blood-transcriptome-mega-analysis-shared-inflammatory-pathways-across-biological-sex-and-modes-of-trauma
#3
Michael S Breen, Daniel S Tylee, Adam X Maihofer, Thomas C Neylan, Divya Mehta, Elisabeth Binder, Sharon D Chandler, Jonathan L Hess, William S Kremen, Victoria B Risbrough, Christopher H Woelk, Dewleen G Baker, Caroline M Nievergelt, Ming T Tsuang, Joseph D Buxbaum, Stephen J Glatt
Transcriptome-wide screens of peripheral blood during the onset and development of posttraumatic stress disorder (PTSD) indicate widespread immune dysregulation. However, little is known as to whether biological sex and the type of traumatic event influence shared or distinct biological pathways in PTSD. We performed a combined analysis of five independent PTSD blood transcriptome studies covering seven types of trauma in 229 PTSD and 311 comparison individuals to synthesize the extant data. Analyses by trauma type revealed a clear pattern of PTSD gene expression signatures distinguishing interpersonal (IP)-related traumas from combat-related traumas...
September 19, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28925016/wall-object-punching-an-important-but-under-recognized-form-of-nonsuicidal-self-injury
#4
Nathan A Kimbrel, Shaun P Thomas, Terrell A Hicks, Michael A Hertzberg, Carolina P Clancy, Eric B Elbogen, Eric C Meyer, Bryann B DeBeer, Georgina M Gross, Paul J Silvia, Sandra B Morissette, Kim L Gratz, Patrick S Calhoun, Jean C Beckham
The present research investigated wall/object punching as a form of nonsuicidal self-injury (NSSI) among 1,143 veterans seeking treatment for posttraumatic stress disorder (PTSD). Wall/object punching was remarkably common in this sample (43%), and its inclusion in the definition of NSSI increased estimated prevalence of recent NSSI by 14%. As expected, wall/object punching was strongly associated with other traditional forms of NSSI, post-NSSI relief, and suicide ideation. Male veterans and veterans with PTSD were significantly more likely to engage in wall/object punching than female veterans and veterans without PTSD...
September 19, 2017: Suicide & Life-threatening Behavior
https://www.readbyqxmd.com/read/28924828/a-network-based-neurobiological-model-of-ptsd-evidence-from-structural-and-functional-neuroimaging-studies
#5
REVIEW
Teddy J Akiki, Christopher L Averill, Chadi G Abdallah
PURPOSE OF REVIEW: Although a fine-grained understanding of the neurobiology of posttraumatic stress disorder (PTSD) is yet to be elucidated, the last two decades have seen a rapid growth in the study of PTSD using neuroimaging techniques. The current review summarizes important findings from functional and structural neuroimaging studies of PTSD, by primarily focusing on their relevance towards an emerging network-based neurobiological model of the disorder. RECENT FINDINGS: PTSD may be characterized by a weakly connected and hypoactive default mode network (DMN) and central executive network (CEN) that are putatively destabilized by an overactive and hyperconnected salience network (SN), which appears to have a low threshold for perceived saliency, and inefficient DMN-CEN modulation...
September 19, 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28924183/the-associations-of-earlier-trauma-exposures-and-history-of-mental-disorders-with-ptsd-after-subsequent-traumas
#6
R C Kessler, S Aguilar-Gaxiola, J Alonso, E J Bromet, O Gureje, E G Karam, K C Koenen, S Lee, H Liu, B-E Pennell, M V Petukhova, N A Sampson, V Shahly, D J Stein, L Atwoli, G Borges, B Bunting, G de Girolamo, S F Gluzman, J M Haro, H Hinkov, N Kawakami, V Kovess-Masfety, F Navarro-Mateu, J Posada-Villa, K M Scott, A Y Shalev, M Ten Have, Y Torres, M C Viana, A M Zaslavsky
Although earlier trauma exposure is known to predict posttraumatic stress disorder (PTSD) after subsequent traumas, it is unclear whether this association is limited to cases where the earlier trauma led to PTSD. Resolution of this uncertainty has important implications for research on pretrauma vulnerability to PTSD. We examined this issue in the World Health Organization (WHO) World Mental Health (WMH) Surveys with 34 676 respondents who reported lifetime trauma exposure. One lifetime trauma was selected randomly for each respondent...
September 19, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28923718/automated-measurement-of-hippocampal-subfields-in-ptsd-evidence-for-smaller-dentate-gyrus-volume
#7
Jasmeet P Hayes, Scott Hayes, Danielle R Miller, Ginette Lafleche, Mark W Logue, Mieke Verfaellie
Smaller hippocampal volume has been consistently observed as a biomarker of posttraumatic stress disorder (PTSD). However, less is known about individual volumes of the subfields composing the hippocampus such as the dentate gyrus and cornu ammonis (CA) fields 1-4 in PTSD. The aim of the present study was to examine the hypothesis that volume of the dentate gyrus, a region putatively involved in distinctive encoding of similar events, is smaller in individuals with PTSD versus trauma-exposed controls. Ninety-seven recent war veterans underwent structural imaging on a 3T scanner and were assessed for PTSD using the Clinician-Administered PTSD Scale...
September 9, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28918648/anticipatory-traumatic-reaction-outcomes-arising-from-secondary-exposure-to-disasters-and-large-scale-threats
#8
Tanya L Hopwood, Nicola S Schutte, Natasha M Loi
Two studies, with a total of 707 participants, developed and examined the reliability and validity of a measure for anticipatory traumatic reaction (ATR), a novel construct describing a form of distress that may occur in response to threat-related media reports and discussions. Exploratory and confirmatory factor analysis resulted in a scale comprising three subscales: feelings related to future threat; preparatory thoughts and actions; and disruption to daily activities. Internal consistency was .93 for the overall ATR scale...
September 1, 2017: Assessment
https://www.readbyqxmd.com/read/28917443/alternative-models-of-dsm-5-ptsd-examining-diagnostic-implications
#9
Siobhan Murphy, Maj Hansen, Ask Elklit, Yoke Yong Chen, Siti Raudzah Ghazali, Mark Shevlin
The factor structure of DSM-5 posttraumatic stress disorder (PTSD) has been extensively debated with evidence supporting the recently proposed seven-factor Hybrid model. However, despite myriad studies examining PTSD symptom structure few have assessed the diagnostic implications of these proposed models. This study aimed to generate PTSD prevalence estimates derived from the 7 alternative factor models and assess whether pre-established risk factors associated with PTSD (e.g., transportation accidents and sexual victimisation) produce consistent risk estimates...
September 9, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28917394/childhood-maltreatment-severity-and-alcohol-use-in-adult-psychiatric-inpatients-the-mediating-role-of-emotion-regulation-difficulties
#10
Christina D Dutcher, Anka A Vujanovic, Daniel J Paulus, Brooke A Bartlett
OBJECTIVE: Emotion regulation difficulties are a potentially key mechanism underlying the association between childhood maltreatment and alcohol use in adulthood. The current study examined the mediating role of emotion regulation difficulties in the association between childhood maltreatment severity (i.e., Childhood Trauma Questionnaire total score) and past-month alcohol use severity, including alcohol consumption frequency and alcohol-related problems (i.e., number of days of alcohol problems, ratings of "bother" caused by alcohol problems, ratings of treatment importance for alcohol problems)...
September 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28917190/posttraumatic-stress-symptoms-and-dissociation-between-childhood-trauma-and-two-different-types-of-psychosis-like-experience
#11
Ji Young Choi
This study examined the roles of posttraumatic stress (PTS) symptoms and dissociation in the relationship between childhood trauma and two different types of psychosis-like experience, including persecutory ideation and aberrant experience, in non-psychotic psychiatric patients. From August 2015 to August 2016, among psychiatric out patients seeking treatment at the Department of Psychiatry at a major teaching medical hospital in Seoul, Korea, 169 patients who had never been diagnosed with a psychotic disorder, including schizophrenia spectrum disorder, bipolar disorder, and/or depressive disorder with psychotic features, completed the Korean Childhood Trauma Questionnaire, the Korean version of the Impact of Event Scale-Revised, the modified Korean version of the Peritraumatic Dissociation Experiences Questionnaire, and the Korean Minnesota Multiphasic Personality Inventory-2 (MMPI-2)...
September 13, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28917088/depression-anxiety-ptsd-and-comorbidity-in-perinatal-women-in-turkey-a-longitudinal-population-based-study
#12
Pelin Dikmen-Yildiz, Susan Ayers, Louise Phillips
OBJECTIVE: (a) to assess prevalence of depression, anxiety and post-traumatic stress disorder (PTSD) and their comorbidity among women during the perinatal period (b) to examine course of those disorders from pregnancy to 6 months postpartum (c) to determine the rates of new-onset cases at 4-6 weeks and 6 months postpartum. DESIGN: A longitudinal population-based study in which participants completed psychosocial measures of depression, anxiety and PTSD in pregnancy (n = 950), 4-6 weeks (n = 858) and 6 months (n = 829) after birth...
September 6, 2017: Midwifery
https://www.readbyqxmd.com/read/28915145/posttraumatic-stress-disorder-symptoms-among-trauma-exposed-inpatient-adolescents-the-role-of-emotional-nonacceptance-and-anxiety-symptom-severity
#13
Andres G Viana, Abigail E Hanna, Elizabeth M Raines, Emma C Woodward, Daniel J Paulus, Erin C Berenz, Michael J Zvolensky
The present investigation examined the role of anxiety symptom severity in the relation between emotional nonacceptance and posttraumatic stress disorder (PTSD) symptoms in a diverse sample of trauma-exposed adolescents admitted for acute psychiatric care at an inpatient state hospital (N = 50; 52.0% women; 44% white; mean [SD] age, 15.1 [0.51] years; range, 12-17 years). Anxiety symptom severity partially accounted for the association between emotional nonacceptance and PTSD total symptoms, and fully accounted for the association between emotional nonacceptance and PTSD symptom cluster severity, even after controlling for covariates...
September 14, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28912423/the-chinese-herbal-formula-free-and-easy-wanderer-ameliorates-oxidative-stress-through-keap1-nrf2-ho-1-pathway
#14
Chunlan Hong, Jingming Cao, Ching-Fen Wu, Onat Kadioglu, Anja Schüffler, Ulrich Kauhl, Sabine M Klauck, Till Opatz, Eckhard Thines, Norbert W Paul, Thomas Efferth
Posttraumatic stress disorder (PTSD) gains a lot of attention due to high prevalence and strong psychological upset, but the etiology remains undefined and effective treatment is quite limited. Growing studies demonstrated the involvement of oxidative stress in various psychiatry diseases, suggesting anti-oxidation therapy might be a strategy for PTSD treatment. Free and Easy Wanderer (FAEW) is a poly-herbal drug clinically used in China for hundreds of years in the treatment of psychiatric disorder. We hypothesized that FAEW exerts clinical effects through the activity against oxidative stress with fluoxetine as antidepressant control drug...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28906364/altered-default-mode-network-configuration-in-posttraumatic-stress-disorder-after-earthquake-a-resting-stage-functional-magnetic-resonance-imaging-study
#15
Xiao-Dong Zhang, Yan Yin, Xiao-Lei Hu, Lian Duan, Rongfeng Qi, Qiang Xu, Guang-Ming Lu, Ling-Jiang Li
The neural substrates of posttraumatic stress disorder (PTSD) are still not fully elucidated. Hence, this study is to explore topological alterations of the default mode network (DMN) in victims with PTSD after a magnitude of 8.0 earthquake using resting-state functional magnetic resonance imaging (rs-fMRI).This study was approved by the local ethical review board, and all participants signed written informed consent. Sixty-two PTSD victims from the 2008 Sichuan earthquake and 62 matched exposed controls underwent rs-fMRI...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28905076/-life-after-ards
#16
REVIEW
B Sensen, S Braune, G de Heer, T Bein, S Kluge
Patients who survive acute respiratory distress syndrome (ARDS) often suffer from long-term physical and psychological sequelae. Lung function is commonly only mildly reduced, whereas general physical activity and walking distance are often compromised. Most markedly, these patients have a high incidence of depression, anxiety, and posttraumatic stress disorder. The rate of cognitive dysfunction is as high as 70-100% at the time of hospital discharge, and remains 46-80% and 20% one year and five years post discharge, respectively...
September 13, 2017: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/28893336/problematic-internet-use-in-gamblers-impact-on-clinical-and-cognitive-measures
#17
Samuel R Chamberlain, Sarah A Redden, Eric Leppink, Jon E Grant
OBJECTIVE: Gambling is a commonplace phenomenon, existing along a continuum from occasional gambling to functionally impairing gambling disorder. The internet may act as a conduit for some gambling behaviors. The impact of problematic internet use on clinical and cognitive features relevant to gambling has received little research attention. METHODS: A total of 206 adults aged 18-30 years who gamble at least five times per year were recruited from the general community and undertook detailed clinical and cognitive assessments...
September 12, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28892237/partners-of-nulliparous-women-with-severe-fear-of-childbirth-a-longitudinal-study-of-psychological-well-being
#18
Elsa Lena Ryding, Sanna Read, Hanna Rouhe, Erja Halmesmäki, Katariina Salmela-Aro, Riikka Toivanen, Maiju Tokola, Terhi Saisto
BACKGROUND: Little is known about the psychological status of partners of women with severe fear of childbirth (FOC). In this longitudinal study from Helsinki University Central Hospital, we investigated FOC, depression, and posttraumatic stress in the partners of women with severe FOC, and possible effects of group psychoeducation and mode of birth. METHODS: During pregnancy, 250 partners of nulliparous women with severe FOC participated, 93 in the intervention group and 157 in the control group...
September 11, 2017: Birth
https://www.readbyqxmd.com/read/28890282/opioid-dosing-trends-over-eight-years-among-us-veterans-with-musculoskeletal-disorders-after-returning-from-service-in-support-of%C3%A2-recent-conflicts
#19
Ling Han, Heather Allore, Joseph Goulet, Harini Bathulapali, Melissa Skanderson, Cynthia Brandt, Sally Haskell, Erin Krebs
PURPOSE: To examine long-term opioid dosing trends among Veterans with chronic pain. METHODS: We identified 79,015 Veterans with musculoskeletal disorders who were dispensed greater than or equal to 1 opioid prescriptions between 2002 and 2009 after returning from recent conflicts. Opioid-dosing trends were examined using a generalized estimating equation while accounting for patient characteristics, temporal and geographic confounding. RESULTS: In total, 472,819 opioid prescriptions were dispensed (mean ± standard deviation: 6...
August 24, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/28890128/characteristics-and-health-care-preferences-associated-with-cardiovascular-disease-risk-among-women-veterans
#20
Karen M Goldstein, Eugene Z Oddone, Lori A Bastian, Maren K Olsen, Bryan C Batch, Donna L Washington
BACKGROUND: Women veterans are at increased risk for cardiovascular disease (CVD), but little is known about comorbidities and healthcare preferences associated with CVD risk in this population. METHODS: We describe the prevalence of CVD-relevant health behaviors, mental health symptoms, and health care use characteristics and preferences among participants of the National Survey of Women Veterans (conducted 2008-2009). FINDINGS: Fifty-four percent of respondents were at risk for CVD (defined as a diagnosis of hypertension, diabetes, current tobacco use, or obesity without CVD)...
September 7, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
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