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Predictors switching dialysis

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https://www.readbyqxmd.com/read/27083497/handgrip-strength-is-an-independent-predictor-of-all-cause-mortality-in-maintenance-dialysis-patients
#1
Barbara Perez Vogt, Mariana Clementoni Costa Borges, Cassiana Regina de Goés, Jacqueline Costa Teixeira Caramori
BACKGROUND & AIMS: Muscle wasting is associated with mortality in dialysis patients. The measurement of muscle mass has some limitations, while muscle strength assessment is simple, safe and allows the recognition of patients at risk of progressing to poor outcomes related to malnutrition. The aim of this study is verify if handgrip strength (HGS) is associated with all-cause mortality in patients in maintenance haemodialysis (HD) and peritoneal dialysis (PD). METHODS: This was an observational retrospective cohort study which included all patients in maintenance HD and PD from July 2012 to October 2014...
March 31, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/26603871/serum-cardiac-troponin-t-and-effective-blood-flow-in-stable-extracorporeal-dialysis-patients
#2
Alicja E Grzegorzewska, Krzysztof Cieszyński, Leszek Niepolski, Andrzej Kaczmarek, Anna Sowińska
PURPOSE: We examined the association between extracorporeal dialysis (ED)-related effective blood flow (eQB) and serum cardiac troponin T (cTnT) as a possible indicator of silent myocardial damage in stable ED patients. METHODS: In a cross-sectional study, cTnT was determined in 247 ED patients dialyzed using stable eQB and dialysate flow (QD). In a prospective study, 91 patients were switched from low-flux (LF) to high-flux (HF) hemodialysis (HD), and subsequently, the eQB increased, and the QD decreased; 65 patients continued LF-HD with stable eQB and QD...
March 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/25765538/improved-survival-of-incident-patients-with-high-volume-haemodiafiltration-a-propensity-matched-cohort-study-with-inverse-probability-of-censoring-weighting
#3
Bernard Canaud, Inga Bayh, Daniele Marcelli, Pedro Ponce, José Ignacio Merello, Konstantin Gurevich, Erzsebet Ladanyi, Ercan Ok, Goran Imamovic, Aileen Grassmann, Laura Scatizzi, Emanuele Gatti
BACKGROUND: Haemodiafiltration (HDF) is the preferred dialysis modality in many countries. The aim of the study was to compare the survival of incident patients on high-volume HDF (HV-HDF) with high-flux haemodialysis (HD) in a large-scale European dialysis population. METHODS: The study population was extracted from 47,979 patients in 369 NephroCare centres throughout 12 countries. Baseline was six months after dialysis initiation; maximum follow-up was 5 years...
2015: Nephron
https://www.readbyqxmd.com/read/24927898/first-year-outcomes-of-incident-peritoneal-dialysis-patients-in-the-united-states
#4
Joseph Pulliam, Nien-Chen Li, Franklin Maddux, Raymond Hakim, Frederic O Finkelstein, Eduardo Lacson
BACKGROUND: Patterns of early outcomes in peritoneal dialysis (PD) are not well studied and dialysis providers need to establish a baseline of key outcomes for continuous quality improvement initiatives. STUDY DESIGN: Retrospective cohort study. SETTING & PARTICIPANTS: Incident PD patients from Fresenius Medical Care, North America from January 1 through December 31, 2009. FACTORS: Case-mix, comorbid illness, and baseline laboratory values...
November 2014: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/24667814/high-sensitivity-c-reactive-protein-predicts-mortality-and-technique-failure-in-peritoneal-dialysis-patients
#5
Shou-Hsuan Liu, Yi-Jung Li, Hsin-Hsu Wu, Cheng-Chia Lee, Chan-Yu Lin, Cheng-Hao Weng, Yung-Chang Chen, Ming-Yang Chang, Hsiang-Hao Hsu, Ji-Tseng Fang, Cheng-Chieh Hung, Chih-Wei Yang, Ya-Chung Tian
INTRODUCTION: An elevated level of serum C-reactive protein (CRP) is widely considered an indicator of an underlying inflammatory disease and a long-term prognostic predictor for dialysis patients. This cross-sectional cohort study was designed to assess the correlation between the level of high-sensitivity CRP (HS-CRP) and the outcome of peritoneal dialysis (PD) patients. METHODS: A total of 402 patients were stratified into 3 tertiles (lower, middle, upper) according to serum HS-CRP level and and followed up from October 2009 to September 2011...
2014: PloS One
https://www.readbyqxmd.com/read/24497601/outcomes-of-peritoneal-dialysis-patients-and-switching-to-hemodialysis-a-competing-risks-analysis
#6
COMPARATIVE STUDY
Jernej Pajek, Alastair J Hutchison, Shiv Bhutani, Paul E C Brenchley, Helen Hurst, Maja Pohar Perme, Angela M Summers, Anand Vardhan
BACKGROUND: We performed a review of a large incident peritoneal dialysis cohort to establish the impact of current practice and that of switching to hemodialysis. METHODS: Patients starting peritoneal dialysis between 2004 and 2010 were included and clinical data at start of dialysis recorded. Competing risk analysis and Cox proportional hazards model with time-varying covariate (technique failure) were used. RESULTS: Of 286 patients (median age 57 years) followed for a median of 24...
May 2014: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/24262505/longitudinal-study-of-small-solute-transport-and-peritoneal-protein-clearance-in-peritoneal-dialysis-patients
#7
Zanzhe Yu, Mark Lambie, Simon J Davies
BACKGROUND AND OBJECTIVES: Peritoneal protein clearance (Pcl) is determined by both effective (small pores) membrane area and relative capillary leakiness (large pores). It is not known how these two components change with duration of peritoneal dialysis (PD) in the context of progressive membrane injury and differential attrition of patients with higher Pcl, which has been associated with increased mortality risk in several studies. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Patients treated continuously from 2000 to 2011 for a minimum of 4 years were selected from the longitudinal prospective Stoke PD Study...
February 2014: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/24078644/technique-survival-in-home-haemodialysis-a-composite-success-rate-and-its-risk-predictors-in-a-prospective-longitudinal-cohort-from-a-tertiary-renal-network-programme
#8
Anuradha Jayanti, Milind Nikam, Leonard Ebah, Gill Dutton, Julie Morris, Sandip Mitra
BACKGROUND: Resurgence of interest in home haemodialysis (HHD) is, in part, due to emerging evidence of the benefits of extended HD regimens, which are most feasibly provided in the home setting. Although specific HHD therapy established at home such as nocturnal HD (NHD) has been reported from individual programmes, little is known about overall HHD success. METHODS: The study included 166 patients who were accepted in the Manchester (UK) HHD training programme through liberal selection criteria...
October 2013: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/24057682/survival-of-incident-patients-on-high-volume-online-hemodiafiltration-compared-to-low-volume-online-hemodiafiltration-and-high-flux-hemodialysis
#9
COMPARATIVE STUDY
Goran Imamović, Rajko Hrvačević, Sonja Kapun, Daniele Marcelli, Inga Bayh, Aileen Grassmann, Laura Scatizzi, Jelena Maslovarić, Bernard Canaud
BACKGROUND: Hemodiafiltration is becoming a preferred treatment modality for dialysis patients in many countries. The volume of substitution fluid delivered has been indicated as an independent mortality risk factor. The aim of this study is to compare patient survival on three different treatment modalities: high-flux hemodialysis, low-volume online HDF (oHDF) and high-volume oHDF. METHODS: Incident hemodialysis and oHDF patients treated in 13 NephroCare centers in Bosnia and Herzegovina, Serbia and Slovenia between January 1, 2007, and December 31, 2011, were included in this epidemiological cohort study...
June 2014: International Urology and Nephrology
https://www.readbyqxmd.com/read/23989045/conversion-from-epoetin-and-darbepoetin-to-c-e-r-a-in-non-dialysis-ckd-patients-a-multicenter-italian-prospective-study-in-nephrology-practice
#10
MULTICENTER STUDY
Roberto Minutolo, Giuseppe Conte, Mario Cozzolino, Pasquale Polito, Carlo Manno, Biagio R Di Iorio, Domenico Santoro, Marina Di Luca, Felice Nappi, Sandro Feriozzi, Ferdinando C Sasso, Luca De Nicola
BACKGROUND: In non-dialysis patients (ND-CKD), C.E.R.A. has been extensively investigated in ESA-naïve subjects but no data are available on its efficacy after switch from other ESA. METHODS: In this prospective, multicenter, open-label study lasting 24 weeks, ND-CKD patients (n = 157) receiving ESA were converted to C.E.R.A. at doses lower than recommended. Primary outcome was the prevalence of Hb target (11-12.5 g/dl). RESULTS: Age was 73 ± 13 years and GFR was 26...
2013: Blood Purification
https://www.readbyqxmd.com/read/23959669/over-dialysis-plasma-rantes-increase-depends-on-heparin-dose-and-cardiovascular-disease-status
#11
RANDOMIZED CONTROLLED TRIAL
B Naumnik, E Koc-Żórawska, M Myśliwiec
PURPOSE: The lifespan of maintenance hemodialysis patients is reduced mainly because of cardiovascular complications due to accelerated atherosclerosis and impaired angiogenesis. We aimed to compare the effect of unfractionated heparin (UFH) and enoxaparin used as anticoagulants during hemodialysis (HD) on circulating levels of heparin-binding, anti-angiogenic Endostatin, pro-inflammatory RANTES (Regulated upon Activation, Normal T cell Expressed and Secreted), and MCP-1 (Monocyte Chemoattractant Protein-1)...
2013: Advances in Medical Sciences
https://www.readbyqxmd.com/read/23432107/resolution-of-adefovir-related-nephrotoxicity-by-adefovir-dose-reduction-in-patients-with-chronic-hepatitis-b
#12
J L Hartono, M O Aung, Y Y Dan, M Gowans, K Lim, Y M Lee, G H Lee, H C Low, P S Tan, M A Thwin, C Soon, L-L Chiu, M J Khoo, E Koay, S G Lim
BACKGROUND: Chronic hepatitis B patients (CHB) treated with adefovir were followed up to evaluate nephrotoxicity and its outcome. AIM: To assess the incidence of renal dysfunction during adefovir therapy in Asian patients and factors associated with it, and evaluate strategies to improve adefovir-related renal dysfunction and their impact on viral suppression. METHODS: Chronic hepatitis B clinic patients from a tertiary hospital on adefovir treatment, with their clinical and laboratory parameters were extracted from the hospital electronic clinical database in an observational study design...
April 2013: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/23159410/feasibility-limits-of-transradial-primary-percutaneous-coronary-intervention-in-acute-myocardial-infarction-in-the-real-life-trap-ami
#13
Barnabas Gellen, Pierre-François Lesault, Florence Canouï-Poitrine, Stéphane Champagne, Gauthier Mouillet, Dionyssis Pongas, Aurélie Le Thuaut, Tomislav Jakljevic, Sélim Boudiche, Marcos de la Vega, Abdelkader Maalej, Aurélie Veugeois, Jean-Luc Dubois-Randé, Emmanuel Teiger
BACKGROUND: There is growing evidence that transradial (TRI) as compared to transfemoral (TFI) percutaneous coronary intervention (PCI) is associated with improved clinical outcome driven by less hemorrhagic complications, in particular in STEMI patients receiving aggressive antithrombotic treatment. Feasibility rate of TRI in STEMI patients has not yet been evaluated. METHODS/RESULTS: Four-hundred seventy-five consecutive STEMI patients (<12h) without cardiogenic shock were prospectively screened for this all-comer single-centre registry between January 2008 and August 2010...
September 30, 2013: International Journal of Cardiology
https://www.readbyqxmd.com/read/22701171/comparison-of-mortality-between-japanese-peritoneal-dialysis-and-hemodialysis-patients-a-5-year-multicenter-follow-up-study
#14
Kazuko Suzuki, Tsuneo Konta, Kazunobu Ichikawa, Ami Ikeda, Hiroki Niino, Masato Hoshikawa, Toshiyuki Takahashi, Hiroshi Abiko, Minoru Ito, Ikuto Masakane, Tomohito Matsunaga, Kosuke Kudo, Hiroko Sato, Noriyuki Degawa, Isao Kubota
To examine the relationship between dialysis modality and prognosis in Japanese patients, we conducted a prospective multicenter observational study. We recruited 83 background-matched peritoneal dialysis (PD) and 83 hemodialysis (HD) patients (average age, 64.9 years; men, 53.6%; diabetic patients, 22.9%; median duration of dialysis, 48 months in all patients) and followed them for 5 years. During the follow-up period, 27 PD patients (16 cardiovascular and 11 non-cardiovascular deaths) and 27 HD patients died (14 cardiovascular and 13 non-cardiovascular deaths)...
2012: International Journal of Nephrology
https://www.readbyqxmd.com/read/22508142/is-there-impact-of-mortality-prior-hemodialysis-therapy-in-peritoneal-dialysis-patients
#15
Yener Koc, Abdulkadir Unsal, Taner Basturk, Tamer Sakaci, Elbis Ahbap-Dal, Ayse Sinangil-Arar, Sennur Kose-Budak, Hasan Kayabasi
AIM: The aim of this study is to investigate the mortality and the factors which may affect it in patients who were transferred to peritoneal dialysis (PD) from hemodialysis (HD), compared to patients assigned to PD as first-line therapy. MATERIAL AND METHODS: A total of 322 patients treated with PD between 2001 and 2010 were evaluated retrospectively. Twenty three patients were excluded and the data of remaining 299 patients (167F, mean follow up time 38.5±26...
May 14, 2012: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/20124193/time-dependent-reasons-for-peritoneal-dialysis-technique-failure-and-mortality
#16
Inna Kolesnyk, Friedo W Dekker, Elisabeth W Boeschoten, Raymond T Krediet
BACKGROUND: Peritoneal dialysis (PD) technique failure is high compared to hemodialysis (HD). There is a lack of data on the impact of duration of PD treatment on technique survival and on whether there is a difference in risk factors with respect to early and late failure. The aim of this study was to clarify these issues by performing a time-dependent analysis of PD technique and patient survival in a large cohort of incident PD patients. METHODS: We analyzed 709 incident PD patients participating in the Netherlands Cooperative Study on the Adequacy of Dialysis (NECOSAD), who started their treatment between 1997 and 2007...
March 2010: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/19200383/timing-causes-predictors-and-prognosis-of-switching-from-peritoneal-dialysis-to-hemodialysis-a-prospective-study
#17
Bernard G Jaar, Laura C Plantinga, Deidra C Crews, Nancy E Fink, Nasser Hebah, Josef Coresh, Alan S Kliger, Neil R Powe
BACKGROUND: The use of peritoneal dialysis (PD) has declined in the United States over the past decade and technique failure is also reportedly higher in PD compared to hemodialysis (HD), but there are little data in the United States addressing the factors and outcomes associated with switching modalities from PD to HD. METHODS: In a prospective cohort study of 262 PD patients enrolled from 28 peritoneal dialysis clinics in 13 U.S. states, we examined potential predictors of switching from PD to HD (including demographics, clinical factors, and laboratory values) and the association of switching with mortality...
2009: BMC Nephrology
https://www.readbyqxmd.com/read/16935120/the-arterial-switch-operation-in-europe-for-transposition-of-the-great-arteries-a-multi-institutional-study-from-the-european-congenital-heart-surgeons-association
#18
MULTICENTER STUDY
George E Sarris, Andrew C Chatzis, Nicolas M Giannopoulos, George Kirvassilis, Hakan Berggren, Mark Hazekamp, Thierry Carrel, Juan V Comas, Duccio Di Carlo, Willem Daenen, Tjark Ebels, Josè Fragata, Victor Hraska, Vladimir Ilyin, Harald L Lindberg, Dominique Metras, Marco Pozzi, Jean Rubay, Heikki Sairanen, Giovanni Stellin, Andreas Urban, Carin Van Doorn, Gerhard Ziemer
OBJECTIVES: This study analyzes the results of the arterial switch operation for transposition of the great arteries in member institutions of the European Congenital Heart Surgeons Association. METHODS: The records of 613 patients who underwent primary arterial switch operations in each of 19 participating institutions in the period from January 1998 through December 2000 were reviewed retrospectively. RESULTS: A ventricular septal defect was present in 186 (30%) patients...
September 2006: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/15930017/switching-from-subcutaneous-to-intravenous-erythropoietin-alpha-in-haemodialysis-patients-requires-a-major-dose-increase
#19
Jack W Galliford, Rao Malasana, Ken Farrington
BACKGROUND: A change in the licensing arrangements for the use of erythropoietin alpha in haemodialysis patients has required a switch in the route of administration from subcutaneous (SC) to intravenous (IV). Previous work suggested that the IV route was less efficacious but studies since the enforced switch have not confirmed this. METHODS: We studied haemoglobin levels and the mean weekly dose of erythropoietin alpha in 86 haemodialysis patients at monthly intervals over the 6 month period before and after a change in the route of administration of erythropoietin alpha from SC to IV...
September 2005: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/15593041/predictive-value-of-troponin-t-levels-for-ischemic-heart-disease-and-mortality-in-patients-on-hemodialysis
#20
Mario Jose Fernández-Reyes, Carmen Mon, Manuel Heras, Paloma Guevara, Mari Carmen Garcia, Rosa Sanchez, Sonia Velasco, Fernando Alvarez-Ude
BACKGROUND: Serum cardiac troponin T (cTnT) levels are elevated in a high percentage of hemodialysis (HD) patients and as a result, they have been considered low specificity for ischemic heart disease (IHD). Recently, several authors have indicated the value of cTnT as a marker of IHD and left ventricular hypertrophy (LVH), as well as a mortality predictor. We try to establish the value of cTnT as an IHD marker and a mortality predictor in our patients on HD. SUBJECTS AND METHODS: Fifty-eight HD patients were prospectively studied from October 2000 to April 2002...
September 2004: Journal of Nephrology
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