Ohad Atia, Rona Lujan, Rachel Buchuk, Shira Greenfeld, Revital Kariv, Yiska Loewenberg Weisband, Natan Ledderman, Eran Matz, Oren Ledder, Eran Zittan, Henit Yanai, Doron Shwartz, Iris Dotan, Daniel Nevo, Dan Turner
BACKGROUND: Since data on predictors of complicated Crohn's disease (CD) from unselected populations are scarce, we aimed to utilize a large nationwide cohort, the epi-IIRN, to explore predictors of disease course in children and adults with CD. METHODS: Data of patients with CD were retrieved from Israel's 4 health maintenance organizations, whose records cover 98% of the population (2005-2020). Time-to-event modeled a complicated disease course, defined as CD-related surgery, steroid-dependency, or the need for >1 class of biologics...
February 8, 2024: Inflammatory Bowel Diseases