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heat pad hypothermia

Li Shao, Nannan Pang, Ping Yan, Fengju Jia, Qi Sun, Wenjuan Ma, Yi Yang
The influence of mild perioperative hypothermia on the immune function and incidence of postoperative wound infections has been suggested, but the specific mechanism is unclear. This study aimed to analyze the body temperature, immune function, and wound infection rates in patients receiving open surgery for gastric cancer. Body temperature was controlled in each patient using one of four different methods: wrapping limbs, head and neck; insulated blankets; warming infusion fluids and insulated blankets; and warming fluids without insulated blankets...
April 9, 2018: Bosnian Journal of Basic Medical Sciences
Shin Nakayama, Noriko Taguchi, Makoto Tanaka
The hydrogen sulfide donor sodium hydrogen sulfide (NaHS) is recognized as a neuroprotective agent, which induces a hibernation-like metabolic state and hypothermia. However, it remains unclear whether it is the sulfide itself or the hypothermia induced by the sulfide that mediates treatment outcomes following cardiac arrest (CA) and cardiopulmonary resuscitation (CPR). We therefore tested whether NaHS improved outcomes following CA/CPR in mice maintained at 35.0°C by active warming during recovery. Adult male mice were subjected to 8 minutes CA/CPR and randomly treated intraperitoneally with either implantation of miniosmotic pump with NaHS (50 μmol/kg/day) for 3 days or vehicle 30 minutes after CPR...
February 12, 2018: Therapeutic Hypothermia and Temperature Management
C J Schuster, D S J Pang
General anaesthesia disrupts thermoregulation in mammals, which can cause hypothermia. Decreases in core body temperature of 1℃ cause significant postoperative complications in humans, and peri-anaesthetic hypothermia in mice increases data variability, which can potentially increase animal use. In rats, the impact of different temperature management strategies on the incidence and severity of hypothermia, and the accuracy of different temperature measurement methods, is unknown. Eighteen adult male and female SD rats were block-randomized to one of three treatment groups: no-warming (NW), limited-warming (LW, heat pad during anaesthesia), and pre-warming (PW, warm air exposure before anaesthesia, followed by heat pad)...
April 2018: Laboratory Animals
Mark L Christensen, Grant S Lipman, Dennis A Grahn, Kate M Shea, Joseph Einhorn, H Craig Heller
OBJECTIVE: To compare the effectiveness of arteriovenous anastomosis (AVA) vs heated intravenous fluid (IVF) rewarming in hypothermic subjects. Additionally, we sought to develop a novel method of hypothermia induction. METHODS: Eight subjects underwent 3 cooling trials each to a core temperature of 34.8±0.6 (32.7 to 36.3°C [mean±SD with range]) by 14°C water immersion for 30 minutes, followed by walking on a treadmill for 5 minutes. Core temperatures (Δtes) and rates of cooling (°C/h) were measured...
June 2017: Wilderness & Environmental Medicine
Bethany S Zarndt, Jessica N Buchta, Lindsey S Garver, Silas A Davidson, Edgar D Rowton, Kenneth E Despain
Small mammals have difficulty maintaining body temperature under anesthesia. This hypothermia is a potential detriment not only to the health and comfort of the animal but also to the integrity of any treatment given or data gathered during the anesthetic period. Using an external warming device to assist with temperature regulation can mitigate these effects. In this study, we investigated the ability of an advanced warming device that uses far-infrared (FIR) heating and responds to real-time core temperature monitoring to maintain a normothermic core temperature in guinea pigs...
November 2015: Journal of the American Association for Laboratory Animal Science: JAALAS
Bomi Park, Taehoon Lee, Karen Berger, Sea Mi Park, Ko-Eun Choi, Thomas M Goodsell, Axel Rosengart
OBJECTIVE: We performed a systematic review of the published evidence regarding nonpharmacologic antishivering interventions in various clinical settings. DATA SOURCES: Studies through November 2014 were identified using predefined search terms in electronic databases, including PubMed, the Cochrane Library, EMBASE: Excerpta Medica (Ovid), and Web of Science. STUDY SELECTION: All identified articles were critically analyzed by applying prespecified criteria...
August 2015: Critical Care Medicine
Yun Jiao, Yuchen Dou, Georgina Lockwood, Amar Pani, Richard Jay Smeyne
BACKGROUND: MPTP and paraquat are two compounds that have been used to model Parkinson's disease in mice. Previous studies in two non-traditional strains of mice have shown that a single dose of MPTP can induce changes in body temperature, while the effects of paraquat have not been examined. Examination of body temperature is important since small fluctuations in an animal's core temperature can significantly affect drug metabolism, and if significant enough can even culminate in an animal's death...
2015: Journal of Parkinson's Disease
K Sánchez-Huerta, J Pacheco-Rosado, M E Gilbert
Thyroid hormone (TH) is essential for a number of physiological processes and is particularly critical during nervous system development. The hippocampus is strongly implicated in cognition and is sensitive to developmental hypothyroidism. The impact of TH insufficiency in the foetus and neonate on hippocampal synaptic function has been fairly well characterised. Although adult onset hypothyroidism has also been associated with impairments in cognitive function, studies of hippocampal synaptic function with late onset hypothyroidism have yielded inconsistent results...
January 2015: Journal of Neuroendocrinology
Rosnah Sutan, Satrinawati Berkat
BACKGROUND: Cultural practice have often overlooked when providing maternal and child health care services. Low birth weight is the second cause of neonatal mortality in the world but it is a major factor in a developing country such as Indonesia. The purpose of this study is to predict the neonatal mortality among low birth weight babies in Aceh Province Indonesia. METHODS: Unmatched case control study was conducted using data from year 2010 to 2012 in 8 selected districts of Aceh Province Indonesia...
2014: BMC Pregnancy and Childbirth
Aleksandra Rashkovska, Roman Trobec, Viktor Avbelj, Matjaž Veselko
PURPOSE: To obtain in vivo data about intra- and extra-articular knee temperatures to assess the effectiveness of two cryotherapeutic methods-conventional cooling with gel-packs and computer controlled cryotherapy following anterior cruciate ligament (ACL) reconstructive surgery. METHODS: Twenty patients were arbitrarily assigned for cryotherapy after ACL reconstruction: 8 patients with frozen gel-packs and 12 patients with computer controlled cryotherapy with constant temperatures of the cooling liquid in the knee pads...
September 2014: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Esther Ezquerro Rodríguez, Yolanda Montes García, Blanca Marín Fernández
The physical methods to control body temperature, either to induce hypothermia, or to increase body temperature, can be of two types: physical methods of external heating or cooling and invasive methods that require complex procedures and technology. There are many strategies for the induction of hypothermia, all based on three of the four basic mechanisms of heat transfer, evaporation, convection and conduction. In the hospital environment the external cooling methods or surface (blankets of cold air or water circulation, plates of hydrogel Artic Sun, methods of cooling helmet) are the most widely used for the induction of therapeutic hypothermia...
October 2012: Revista de Enfermería
Nirav G Shah, Mark J Cowan, Edward Pickering, Houtan Sareh, Majid Afshar, Dawn Fox, Jennifer Marron, Jennifer Davis, Keith Herold, Carl B Shanholtz, Jeffrey D Hasday
PURPOSE: This study had 2 objectives: (1) to quantify the metabolic response to physical cooling in febrile patients with systemic inflammatory response syndrome (SIRS) and (2) to provide proof for the hypothesis that the efficiency of external cooling and the subsequent shivering response are influenced by site and temperature of surface cooling pads. METHODS: To quantify shivering thermogenesis during surface cooling for fever, we monitored oxygen consumption (VO(2)) in 6 febrile patients with SIRS during conventional cooling with cooling blankets and ice packs...
December 2012: Journal of Critical Care
Joseph Yuk Sang Ting
The rewarming benefit of anterior torso heat pad application in mildly hypothermic conscious adult trauma patients remains inconclusive in this randomized comparative clinical trial. There was no between-group rewarming gain in ear canal temperature when an anterior torso chemical heat pad was compared with blankets. Patient awareness, and favorable perception of, being administered the active intervention (heat pad) could explain the significant improvement in patient-rated cold discomfort discerned with the heat pad...
2012: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Ying Wang, Jianhua Feng, Guoxing You, Xuemei Kan, Longxiang Qiu, Gan Chen, Dawei Gao, Wei Guo, Lian Zhao, Hong Zhou
BACKGROUND: Hypothermia is common during hemorrhagic shock. To warm the victims or not has been controversial. This study aims to investigate the effect of warming during the initial time of hemorrhage on body temperature, blood pressure, and survival in rat hemorrhagic shock models. METHODS: Forty anesthetized rats were divided into control group (n = 20) and warming group (n = 20). The rats of control group were placed on a wooden pad without heating, and the rats of warming group were placed on a heating pad maintained at 37°C ± 0...
December 2011: Journal of Trauma
Sedef Bayata, Aylin Türel Ermertcan
Heat has been used as a medicinal and healing modality throughout human history. Today, thermotherapy is being studied in the treatment of many diseases. Although the exact anti-infective mechanism of thermotherapy is yet to be solved, this historically important healing method has shown significant results in the treatments of a variety of dermatological infectious diseases ranging from simple acne to bacterial, parasitic and viral infections, in modern medicine. Induction of cellular apoptosis in medium doses and necrosis in high doses has made thermotherapy an important modality in the treatment of malignant tumors...
September 2012: Cutaneous and Ocular Toxicology
Peter Lundgren, Otto Henriksson, Peter Naredi, Ulf Björnstig
BACKGROUND: Prevention and treatment of hypothermia by active warming in prehospital trauma care is recommended but scientific evidence of its effectiveness in a clinical setting is scarce. The objective of this study was to evaluate the effect of additional active warming during road or air ambulance transportation of trauma patients. METHODS: Patients were assigned to either passive warming with blankets or passive warming with blankets with the addition of an active warming intervention using a large chemical heat pad applied to the upper torso...
October 21, 2011: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Adam J Singer, Eric Wang, Breena R Taira, Nicole Steinhauff, Jean Rooney, Thomas Zimmerman
OBJECTIVES: Early surface cooling of burns reduces pain and depth of injury and improves healing. However, there are concerns that cooling of large burns may result in hypothermia and worsen outcomes. In contrast, controlled mild hypothermia improves outcomes after cardiac arrest and traumatic brain injury. The authors hypothesized that controlled mild hypothermia would prolong survival in a rat model of large scald burns. METHODS: Thirty-six Sprague-Dawley rats (250-300 g) were anesthetized with 40 mg/kg intramuscular ketamine and 5 mg/kg xylazine, with supplemental inhalational isoflurane as needed...
March 2011: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
A B Roehl, A Teubner, S Funcke, A Goetzenich, R Rossaint, R Tolba, M Hein
Hypothermia can be caused by anaesthesia and/or surgery and represents a daily challenge in the operating room. Experimental animal surgery settings typically use heating pads or warming blankets to maintain the rodent's body temperature during long-lasting experiments. Warming is crucial in small animal experiments because these animals quickly lose temperature due to their large body surface to body weight ratio. While establishing a left ventricular infarction model in rats, we inserted a rectal temperature probe...
January 2011: Laboratory Animals
Craig R Denegar, Devon R Dougherty, Jacob E Friedman, Maureen E Schimizzi, James E Clark, Brett A Comstock, William J Kraemer
OBJECTIVE: This investigation assessed preferences for, and effects of, 5 days of twice daily superficial heat, cold, or contrast therapy applied with a commercially available system permitting the circulation of water through a wrap-around garment, use of an electric heating pad, or rest for patients with level II-IV osteoarthritis (OA) of the knee. METHODS: We employed a within subject, randomized order design to study 34 patients receiving each treatment in 1-week blocks...
2010: Clinical Interventions in Aging
Katisha D Smith, Liang Zhu
Brain hypothermia induced by a temperature reduction of the spinal fluid using a torso-cooling pad is evaluated as a cooling alternative for traumatic injury patients. A theoretical model of the human head is developed to include its tissue structures and their contribution to local heat transfer. The Pennes bioheat equation and finite element analysis are used to predict the temperature distribution in the head region. The energy balance in the cerebrospinal fluid (CSF) layer surrounding the brain during mixing of the CSF and cold spinal fluid is also formulated to predict the CSF temperature reduction...
August 2010: Medical & Biological Engineering & Computing
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