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https://www.readbyqxmd.com/read/29662727/paratesticular-serous-papillary-carcinoma-of-high-grade-and-malignant-potential-a-rare-case-with-a-role-for-adjuvant-therapy
#1
Jacob Lifton, Saum Ghodoussipour, Guang-Qian Xiao, Tanya Dorff, Jeffrey Loh-Doyle, Stuart D Boyd
Paratesticular serous papillary carcinomas are very rare, with less than 40 cases reported in the literature. These neoplasms are Müllerian in origin, and more commonly seen as epithelial-type ovarian cancer. Given the rarity of this tumor in men, staging and recommended treatment options do not exist. Herein, we present the case of a 35-year-old male with high-grade invasive serous papillary carcinoma. He was diagnosed after left radical orchiectomy for paratesticular mass and subsequently treated with adjuvant chemotherapy according to existing recommendations for its ovarian counterpart...
February 13, 2018: Curēus
https://www.readbyqxmd.com/read/29593931/a-case-of-fibrous-pseudotumor-in-the-scrotum-challenge-for-diagnosis-and-testicular-preservation
#2
Hirotake Kodama, Shingo Hatakeyama, Teppei Matsumoto, Toshikazu Tanaka, Hirotaka Horiguchi, Yuka Kubota, Hayato Yamamoto, Atsushi Imai, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Chikara Ohyama
A paratesticular fibrous pseudotumor is a relatively rare benign disease. Preoperatively diagnosing a fibrous pseudotumor is challenging because distinguishing these masses from malignant tumors on the basis of clinical and radiological findings can be difficult. We present a case of a 28-year-old man who presented with a painless palpable mass in the right scrotum; the fibrous pseudotumor of the tunica vaginalis was treated with organ-sparing surgery. Computed tomography and magnetic resonance imaging revealed paratesticular tumors...
2018: Case Reports in Urology
https://www.readbyqxmd.com/read/29556392/giant-paratesticular-liposarcoma-a-case-report-and-review-of-the-literature
#3
Zuwei Li, Liang Zhou, Liwen Zhao, Peijie Chen, Yifeng Liu, Yu Ding, Shuolei Sun, Shangqi Yang, Yongqing Lai
Paratesticular liposarcoma is an infrequent tumor characterized by a growing, painless, inguinal or scrotal mass. Only about 200 cases have been reported as of yet in literature, however there are a few cases regarding giant paratesticular liposarcoma measuring over 10 cm. The disease may be commonly misdiagnosed prior to operation. Improper treatment tends to lead to local recurrence and distant metastasis. The current report presents a case of a 51-year-old patient with a large, painless right scrotum. Magnetic resonance imaging revealed a 7...
April 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29541584/high-grade-metastatic-paratesticular-cystadenocarcinoma
#4
Lilah Maria Carvas Monteiro, Luis Felipe Brandão, Leonardo Cardili, Marcus Vinícius Sadi
No abstract text is available yet for this article.
March 2018: Urology Case Reports
https://www.readbyqxmd.com/read/29532681/dedifferentiated-liposarcoma-with-rhabdomyosarcomatous-differentiation-producing-hcg-a-case-report-of-a-diagnostic-pitfall
#5
Elena Maryamchik, Kirill A Lyapichev, Bradford Halliday, Andrew E Rosenberg
We report a first case of paraneoplastic human chorionic gonadotropin (HCG) production in a dedifferentiated liposarcoma with rhabdosarcomatous differentiation in an 83-year-old man with a retroperitoneal mass, unilateral scrotal enlargement, and a serum HCG level of 843 IU/L. Core biopsy of the retroperitoneal mass revealed rhabdomyosarcoma. Orchiectomy revealed a paratesticular dedifferentiated liposarcoma with rhabdosarcomatous differentiation. Fluorescence in situ hybridization analysis performed on both the retroperitoneal and paratesticular masses revealed amplification of MDM2...
March 1, 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29508464/cytomorphology-of-proximal-epithelioid-sarcoma-in-the-paratesticular-location
#6
N S Stephen, D Gochhait, P Dehuri, H Subramanian, R S Goldar
No abstract text is available yet for this article.
March 6, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29506850/retroperitoneal-lymph-node-staging-in-paratesticular-rhabdomyosarcoma-are-we-meeting-expectations
#7
Emma C Hamilton, Charles C Miller, Michael Joseph, Winston W Huh, Andrea A Hayes-Jordan, Mary T Austin
BACKGROUND: Staging retroperitoneal lymph node dissection (RPLND) for paratesticular rhabdomyosarcoma (RMS) is recommended for all patients aged ≥10 y. The purpose of this study was to evaluate adherence with surgical resection guidelines for RPLND in patients with paratesticular RMS as a measure for surgical quality. MATERIALS AND METHODS: All patients with paratesticular RMS were identified in the Surveillance, Epidemiology, and End Results database from 1973 to 2012...
April 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29503221/collaborating-with-our-adult-colleagues-a-case-series-of-robotic-surgery-for-suspicious-and-cancerous-lesions-in-children-and-young-adults-performed-in-a-free-standing-children-s-hospital
#8
Briony K Varda, Patricia Cho, Andrew A Wagner, Richard S Lee
BACKGROUND: In adult urologic oncology the use of robotics has become commonplace; in pediatric urology it is rare. Herein, we describe a collaboration between an adult and a pediatric urologist performing robotic surgery for children and young adults with suspicious or cancerous genitourinary (GU) lesions. OBJECTIVES: To evaluate clinical and oncologic outcomes in children and young adults undergoing robotic surgery for suspicious or cancerous lesions of the GU tract; to describe our collaborative model between an adult and pediatric surgeon at a free-standing children's hospital...
March 2, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29468306/paratesticular-alveolar-rhabdomyosarcomas-do-not-harbor-typical-translocations-a-distinct-entity-with-favorable-prognosis
#9
Tobias M Dantonello, Christian Vokuhl, Monika Scheer, Monika Sparber-Sauer, Sabine Stegmaier, Guido Seitz, Heike Scheithauer, Jörg Faber, Iris Veit-Friedrich, Peter Kaatsch, Stefan S Bielack, Thomas Klingebiel, Ewa Koscielniak
The alveolar subtype of rhabdomyosarcoma (RMA) is a strong risk factor. Cases of RMA located in paratesticular sites have however been reported to have similar outcomes to those of embryonal rhabdomyosarcoma (RME). We wanted to re-evaluate the impact of subtype in paratesticular rhabdomyosarcoma (PT-RMS). Patients from a population-based cohort diagnosed with paratesticular RMA in 1990-2013 were analyzed. All tumor samples were re-reviewed using conventional morphology, immunohistochemistry, and molecular testing...
March 2018: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/29411910/paratesticular-seminoma-echographic-features-and-histological-diagnosis-with-review-of-the-literature
#10
Andrea Palicelli, Pierluigi Neri, Giansilvio Marchioro, Paolo De Angelis, Gianmarco Bondonno, Antonio Ramponi
Primary extratesticular seminomas exceptionally occur in the epididymis or in the paratesticular region/spermatic cord. Some old papers included poor histological description or insufficient photographic documentation, reducing the number of faithful cases: an up-to-date systematic review is lacking. We report the 4th primary seminoma of the paratesticular region/spermatic cord in a 35-year-old man, including the first echographic description. We provide review of the literature and etiopathogenetic discussion...
February 7, 2018: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/29325584/adenomatoid-tumor-of-the-testis-mimicking-malignant-testicular-cancer-on-multiparametric-ultrasound
#11
Renate Pichler, Gennadi Tulchiner, Fabian Steinkohl, Afschin Soleiman, Wolfgang Horninger, Isabel Maria Heidegger, Friedrich Aigner
BACKGROUND: Adenomatoid tumor is one of the most common histological subtypes of paratesticular cancer arising from the epididymis. In very rare cases, these tumors appear as intratesticular lesions originating in the tunica albuginea, representing a diagnostic challenge. CASE PRESENTATION: We present a case of a 51-year-old man with a small (0.9 cm) hyperechoic lesion of the left testicle mimicking testicular cancer on multiparametric ultrasound. The lesion was localized in the peripheral zone, confirming vascularization and increased stiffness on contrast-enhanced ultrasound and real-time elastography...
January 11, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29323080/recurrent-leiomyosarcoma-scrotum-an-important-differential-in-scrotal-masses
#12
Ranjan Agrawal, Miti Gupta, Nitesh Mohan, Jagdamba Sharan, Parbodh Kumar
Soft tissue sarcomas of the genitourinary tract are rare. Paratesticular sarcomas are extremely rare with majority of scrotal masses localizing to the testis and being neoplastic in nature. Paratesticular leiomyosarcomas (LMSs) are located in the spermatic cord, epididymis, or scrotum. However, their location in the scrotal skin or subcutaneous tissue is extremely rare. Only 10 cases have been reported from India previously. Ours is the 11th case. A 50-year-old male presented with a recurrent scrotal mass which was painless and gradually increasing in size...
October 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29310184/re-paratesticular-rhabdomyosarcoma-importance-of-initial-therapy
#13
Jerome P Richie
No abstract text is available yet for this article.
January 2018: Journal of Urology
https://www.readbyqxmd.com/read/29301813/paratesticular-myositis-ossificans-of-the-spermatic-cord
#14
Justin M Hintze, Kevin O'Hare, Ted McDermott, Arun Z Thomas
A 56-year-old man presented with a painless scrotal lump, enlarging over the preceding 1 month. The lump was roughly 1 cm in size, and located in his left hemiscrotum and separate from the testis. An ultrasound revealed an echogenic focus with dystrophic tissue calcification. Subsequent surgical excision and histopathological analysis revealed it to be late-stage myositis ossificans, a benign, extraosseous formation of the bone or cartilage. We report of only the second described case of myositis ossificans of the spermatic cord in the literature to date...
January 4, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29285372/malignant-mesothelioma-of-the-tunica-vaginalis-testis-a-case-report-and-literature-review
#15
Neng Zhang, Ni Fu, Su Peng, Xu Luo
Malignant mesothelioma of the tunica vaginalis testis is an extremely rare tumor without specific clinical manifestations, mainly including hydrocele formation and a painless mass. We herein present the case of a patient with hydrocele of the left testis, without any other complaints. Tunica vaginalis subinvolution was performed, and postoperative pathological examination revealed a malignant mesothelioma arising from the left tunica vaginalis testis. Whole-body positron emission tomography-computed tomography (PET-CT) and subsequent abdominal and pelvic magnetic resonance imaging (MRI) revealed no evidence of local lymphadenopathy...
December 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29260641/benign-fibrous-pseudotumor-resulting-in-orchiectomy-despite-intraoperative-frozen-section
#16
Tomy Y Perez, Brian J O'Hara, Irvin H Hirsch
Fibrous pseudotumors are rare benign lesions that originate within the paratesticular tissues. Local excision is the preferred method of treatment of these tumors over radical orchiectomy, however a definitive diagnosis must be made beforehand given the similarity of these tumors to malignant entities. We present a case of fibrous pseudotumor of the tunica vaginalis and cauda epididymis. A diagnosis of fibrous pseudotumor could not be established despite the use of intraoperative frozen section, therefore necessitating radical orchiectomy...
December 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29240742/paediatric-testicular-tumours-in-a-new-zealand-centre
#17
REVIEW
Timothy Little, Shareena Lala, Vipul Upadhyay
AIM: This is a 12-year, single-centre retrospective review of paediatric testicular tumours and review of the world literature on paediatric testicular tumours. The aim was to identify presenting features, the range of pathology and management of such tumours in comparison with other published series. METHODS: The hospital's pathology database was searched for all testicular and paratesticular tissue submitted for patients younger than 16 years of age during the 12-year study period January 2000 to December 2011, and patients with testicular tumours identified...
December 15, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29203999/precocious-paratesticular-metastasis-from-well-differentiated-neuroendocrine-tumour-of-ileocaecal-junction-a-case-report-and-review
#18
Abhay Kattepur, Girish Kundgulwar, Mukta Ramadwar, Avanish Saklani
No abstract text is available yet for this article.
December 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29203187/paratesticular-liposarcoma-masquerading-as-an-inguinal-hernia
#19
Kerry L Thomas, Ricardo J Gonzalez, Evita Henderson-Jackson, Jamie T Caracciolo
A man with left scrotal swelling felt to represent inguinal hernia underwent computed tomography scan for reported bleeding after prostate biopsy. Computed tomography scan revealed a 15-cm extratesticular left scrotal mass containing both fat and soft tissue components, raising concern for dedifferentiated liposarcoma. At surgery and pathology, the mass was separate from the left testis, epididymis, and spermatic cord. Histopathologic findings were consistent with paratesticular dedifferentiated liposarcoma...
December 1, 2017: Urology
https://www.readbyqxmd.com/read/29201230/inhibition-of-penile-tunica-albuginea-myofibroblasts-activity-by-adipose-derived-stem-cells
#20
Hesong Jiang, Qingqiang Gao, Xiaoyan Che, Leilei Zhu, Zheng Zhang, Yun Chen, Yutian Dai
The activation of tunica albuginea myofibroblasts (MFs) serves an essential role in Peyronie's disease (PD). Increasing evidence has reported that adipose tissue-derived stem cells (ADSCs) have been demonstrated to attenuate the symptoms of PD in animal models. However, the mechanisms of the antifibrotic effects of ADSCs in PD remain to be fully elucidated. In the present study, the inhibitory effects and possible mechanism of ADSCs on the activation of MFs derived from rat penile tunica albuginea were investigated...
November 2017: Experimental and Therapeutic Medicine
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