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https://www.readbyqxmd.com/read/27340635/clinical-study-to-evaluate-the-association-between-sensorineural-hearing-loss-and-diabetes-mellitus-in-poorly-controlled-patients-whose-hba1c%C3%A2-8
#1
C V Srinivas, V Shyamala, B R Shiva Kumar
The relationship between sensorineural hearing loss (SNHL) and Diabetes mellitus has been known since more than 150 years. The pathophysiology of diabetes related hearing loss is speculative. Hearing loss is usually, bilateral, gradual onset, affecting higher frequencies. This study aims at knowing the prevalence of SNHL in DM and its relation to age, sex, duration of DM and control of DM. A total of 50 type 2 diabetics of age group 30-65 years were involved in the study. FBS, PPBS, HbA1c of all the subjects were done and later subjected to PTA...
June 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/24128283/audiovestibular-functions-in-noninsulin-dependent-diabetes-mellitus
#2
Halil Erdem Özel, Mahmut Özkiriş, Zeliha Kapusuz Gencer, Levent Saydam
CONCLUSION: This study supports the proposition that vestibular dysfunction and sensorineural hearing loss (SNHL) may be considered among the complications due to noninsulin-dependent diabetes mellitus (NIDDM). OBJECTIVE: The aim of this study was to evaluate the audiovestibular functions in patients with NIDDM and to determine if there is any correlation between audiovestibular dysfunction and the duration of the disease. METHODS: A total of 104 patients diagnosed with NIDDM and 104 nondiabetic control subjects made up the study group...
January 2014: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/24121821/neutrophil-lymphocyte-ratio-as-a-new-predictive-and-prognostic-factor-at-the-hearing-loss-of-diabetic-patients
#3
Sahin Ulu, Abdulkadir Bucak, M Sena Ulu, Ahmet Ahsen, Abidin Duran, Fatih Yucedag, Abdullah Aycicek
Diabetes mellitus (DM) is a systemic inflammatory disease. Sensorineural hearing loss (SNHL) is seen more frequently in diabetic patients and it is believed that vascular complications of DM may be the cause of SNHL via inflammation. Neutrophil-to-lymphocyte ratio (NLR) was defined as a novel-potential marker to determine inflammation. We aimed to investigate the relationship between NLR levels and SNHL in diabetic patients using high-frequency audiometry (8–16 kHz) for the first time. The study included 58 patients diagnosed with DM...
October 2014: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/23219819/a-novel-mt-co1-m-6498c-a-variation-associated-with-the-m-7444g-a-mutation-in-the-mitochondrial-coi-trna-ser-ucn-genes-in-a-patient-with-hearing-impairment-diabetes-and-congenital-visual-loss
#4
Emna Mkaouar-Rebai, Imen Chamkha, Thouraya Kammoun, Olfa Alila-Fersi, Hajer Aloulou, Mongia Hachicha, Faiza Fakhfakh
Mitochondrial diseases are a clinically heterogeneous group of disorders that arise as a result of dysfunction of the mitochondrial respiratory chain. Sensorineural hearing loss (SNHL) has been described in association to different mitochondrial multisystem syndromes, often involving the central nervous system, neuromuscular, or endocrine organs. In this study, we described a Tunisian young girl with hearing impairment, congenital visual loss and maternally inherited diabetes. No mutation was found in the mitochondrial tRNA(Leu(UUR)) and the 12S rRNA genes...
January 11, 2013: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/22808909/molecular-and-hereditary-mechanisms-of-sensorineural-hearing-loss-with-focus-on-selected-endocrinopathies
#5
REVIEW
I Masindova, L Varga, J Stanik, L Valentinova, M Profant, I Klimes, D Gasperikova
Hearing loss is one of the most widespread sensory disorders. The incidence of deafness in general population is 1:1000 newborns. About one half of the cases of the congenital sensorineural hearing loss (SNHL) is inherited. Recessive mutations in the gap junction beta 2 (GJB2) gene are the most common genetic causes of the nonsyndromic SNHL. The GJB2 encodes a protein connexin 26 which forms a subunit of gap junction essential for the correct function of the inner ear. The syndromic SNHL is associated with a wide range of other symptoms, which encompass also dysfunctions of endocrine organs...
July 2012: Endocrine Regulations
https://www.readbyqxmd.com/read/21218721/diabetes-mellitus-and-sensorineural-hearing-loss-among-non-elderly-people
#6
M Mozaffari, A Tajik, N Ariaei, F Ali-Ehyaii, H Behnam
One ofthe known complications of diabetes is hearing impairment. This comparative study in Tehran, Islamic Republic of Iran, aimed to evaluate the association of diabetes mellitus and sensorineural hearing loss (SNHL) among a non-elderly population. Among 160 subjects aged < 60 years with no history of occupational noise exposure (80 diabetics and 80 age- and sex-matched non-diabetic controls), 45% of diabetic patients and 20% of controls had SNHL (OR 3.5, 95% CI: 1.6-6.6). Age at onset and duration of diabetes were associated with SNHL...
September 2010: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/11587074/frequency-and-clinical-features-of-patients-with-sensorineural-hearing-loss-associated-with-the-a3243g-mutation-of-the-mitochondrial-dna-in-otorhinolaryngic-clinics
#7
H Nagata, K Kumahara, T Tomemori, Y Arimoto, K Isoyama, K Yoshida, A Konno
The A3243G mutation of the mitochondrial gene is a cause of maternally inherited diabetes and deafness. The aim of this study was to evaluate the frequency and clinical features of this mutation in patients with sensorineural hearing loss (SNHL) in otorhinolaryngic clinics. The frequency of the A3243G mutation in 230 patients with SNHL was 1.74% (4/230). Three of the four patients had diabetes mellitus (DM) and were already aware that they had the mutation. The other had cardiomyopathy but not DM, and proved to have the mutation in this study...
2001: Journal of Human Genetics
https://www.readbyqxmd.com/read/8544626/bilateral-sensorineural-hearing-loss-associated-with-the-point-mutation-in-mitochondrial-genome
#8
T Oshima, N Ueda, K Ikeda, K Abe, T Takasaka
Mitochondrial DNA (mtDNA) mutation associated with sensorineural hearing loss (SNHL) has previously been described in MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes) and in aminoglycoside-induced deafness. The authors of this study report three cases of SNHL associated with mtDNA mutation (3243A-->G). They examined the clinical features of this type of SNHL by audiologic studies and examined the mtDNA mutation by the polymerase chain reaction technique. In the three cases described, the SNHL had an adult onset and was bilateral and symmetrical...
January 1996: Laryngoscope
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