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https://www.readbyqxmd.com/read/29031173/an-unusual-case-of-transpelvic-impalement-injury-a-case-report
#1
Mushrek Alani, Saeed Mahmood, Ayman El-Menyar, Sajid Atique, Hassan Al-Thani, Ruben Peralta
INTRODUCTION: Impalement injury is a rare type of mechanical injury following forceful insertion of projecting object into the body. Careful planning for removal of the impaling object is essential to decrease the blood loss and preserve the function of the injured organ. PRESENTATION OF CASE: A 27 year-old male fell from 4m height over a U shaped projecting up metallic bar. The bar penetrated the left side of the pelvis and traversed through the left iliac bone causing a comminuted fracture in the supra-acetabular region extending to the left psoas muscle, injuring the viscera and causing fracture of the right femur...
October 5, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29031133/nmr-diffusometry-data-sampling-optimization-for-mixture-analysis
#2
Florence Franconi, Laurent Lemaire, Benjamin Siegler, Jean-Christophe Gimel, Patrick Saulnier
NMR diffusometry is a powerful but challenging method to analyze complex mixture. Each component diffuses differently, from the faster small species to the slower large species, corresponding to different signal attenuation. However, the method is highly sensitive to the quality of the acquired data and the performance of the processing used to resolve multiexponential signals influences. Adapting the signal decay sampling to the mixture composition is one way to improve the precision of the measure. In this work, we propose a prediction tool, based on the calculation of the Cramér-Rao lower bound to minimize the variance of diffusion coefficient estimation in order to determine the optimal number of diffusion gradient steps, the best diffusion gradient sampling (among linear, exponential, quadratic and sigmoidal ones) and the optimal maximum diffusion factor...
October 2, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29029067/pharmacodynamics-of-fosfomycin-against-esbl-and-or-carbapenemase-producing-enterobacteriaceae
#3
Fiona Fransen, Kelly Hermans, Maria J B Melchers, Claudia C M Lagarde, Joseph Meletiadis, Johan W Mouton
Background: The increase in antibiotic resistance in Gram-negative bacteria and the limited therapeutic options due to the shortage of new antibiotics have increased the interest of the 'old' antibiotic fosfomycin in the treatment of infections. However, there are contradictory reports on the pharmacodynamics of and emergence of resistance to fosfomycin. Methods: Time-kill assays were performed with 11 ESBL-positive and 3 ESBL-negative strains, exposing the bacteria to 2-fold static concentrations from 0...
October 4, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29024372/feedback-kinetics-in-mechanochemistry-the-importance-of-cohesive-states
#4
Stuart Lloyd James, Ben Hutchings, Peijun Hu, Lei Gao, Deborah Elizabeth Crawford
Although mechanochemical synthesis is becoming more widely applied and even commercialised, greater basic understanding is needed if the field is to progress on less of a trial-and-error basis. We report that a mechanochemical reaction in a ball mill exhibits unusual sigmoidal feedback kinetics that differ dramatically from the simple first-order kinetics for the same reaction in solution. An induction period followed by a rapid increase in reaction rate before the rate decreases again as the reaction goes to completion...
October 12, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29021674/the-efficacy-of-sagittal-cervical-spine-subtyping-investigating-radiological-classification-methods-within-150-asymptomatic-participants
#5
Lee Daffin, Max C Stuelcken, Mark G L Sayers
AIMS: The aim of this study is to (1) compare and contrast cervical subtype classification methods within an asymptomatic population, and (2) identify inter-methodological consistencies and describe examples of inconsistencies that have the potential to affect subtype classification and clinical decision-making. METHODS: A total of 150 asymptomatic 18-30-year-old participants met the strict inclusion criteria. An erect neutral lateral radiograph was obtained using standard procedures...
July 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/29019575/colon-cancer-surgery-in-patients-operated-on-an-emergency-basis
#6
Rodrigo Felippe Ramos, Lucas Carvalho Santos Dos-Reis, Beatriz Esteves Borgeth Teixeira, Igor Maroso Andrade, Jaqueline Suelen Sulzbach, Ricardo Ary Leal
OBJECTIVE: to study the epidemiological profile of patients with colorectal cancer operated on an emergency basis at the Bonsucesso Federal Hospital. METHODS: this is a retrospective study of patients operated between January 1999 and December 2012. We analyzed the following variables: age, gender, clinical data, TMN staging, tumor location, survival and types of surgery. RESULTS: we evaluated 130 patients in the study period. The most frequent clinical picture was intestinal obstruction, in 78% of cases...
September 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28994611/modeling-the-survival-of-salmonella-enteritidis-and-salmonella-typhimurium-during-the-fermentation-of-yogurt
#7
Derya Savran, Fernando Pérez-Rodríguez, A Kadir Halkman
The objective of this study was to evaluate the behavior of Salmonella Enteritidis and Salmonella Typhimurium, the two most important serovars of salmonellosis , during the fermentation of yogurt. The microorganisms were enumerated in milk throughout the fermentation process at three initial inoculum levels (3, 5 and 7 log CFU/mL). DMFit software was used in the fitting procedure of the data (IFR, Norwich, UK, Version 3.5). The data provided sigmoidal curves that were successfully displayed with the Baranyi model...
January 1, 2017: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/28993881/maximal-rate-of-heart-rate-increase-correlates-with-fatigue-recovery-status-in-female-cyclists
#8
Maximillian J Nelson, Clint R Bellenger, Rebecca L Thomson, Eileen Y Robertson, Kade Davison, Daniela Schäfer Olstad, Jonathan D Buckley
PURPOSE: Being able to identify how an athlete is responding to training would be useful to optimise adaptation and performance. The maximal rate of heart rate increase (rHRI), a marker of heart rate acceleration has been shown to correlate with performance changes in response to changes in training load in male athletes; however, it has not been established if it also correlates with performance changes in female athletes. METHODS: rHRI and cycling performance were assessed in six female cyclists following 7 days of light training (LT), 14 days of heavy training (HT) and a 10 day taper period...
October 9, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28993108/evaluation-of-interfractional-variation-of-organs-and-displacement-of-catheters-during-high-dose-rate-interstitial-brachytherapy-for-gynecologic-malignancies
#9
Soyoung Lee, Ellis Rodney, Bryan Traughber, Tithi Biswas, Valdir Colussi, Tarun Podder
PURPOSE: To investigate the dosimetric effects due to interfractional changes in catheter position and variation in patient's anatomy during the course of interstitial high-dose-rate (HDR) brachytherapy. METHODS AND MATERIALS: A total of 15 patients with either cervical or vaginal cancer underwent interstitial HDR brachytherapy. Interstitial catheters and fiducials were placed under fluoroscopy and intraoperative 3T MRI to confirm the desired catheter placement for adequate target volume coverage...
October 6, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28992639/open-peroral-endoscopic-myotomy-for-achalasia-with-sigmoid-shaped-esophagus
#10
Wei Liu, Ling Liu, Hong-Lin Chen, Hong-Ze Zeng, Chun-Cheng Wu, Lian-Song Ye, Bing Hu
No abstract text is available yet for this article.
October 9, 2017: Endoscopy
https://www.readbyqxmd.com/read/28992595/electrical-current-generation-in-microbial-electrolysis-cells-by-hyperthermophilic-archaea-ferroglobus-placidus-and-geoglobus-ahangari
#11
Yasemin D Yilmazel, Xiuping Zhu, Kyoung-Yeol Kim, Dawn E Holmes, Bruce E Logan
Few microorganisms have been examined for current generation under thermophilic (40-65°C) or hyperthermophilic temperatures (≥80°C) in microbial electrochemical systems. Two iron-reducing archaea from the family Archaeoglobaceae, Ferroglobus placidus and Geoglobus ahangari, showed electro-active behavior leading to current generation at hyperthermophilic temperatures in single-chamber microbial electrolysis cells (MECs). A current density (j) of 0.68±0.11A/m(2) was attained in F. placidus MECs at 85°C, and 0...
October 2, 2017: Bioelectrochemistry
https://www.readbyqxmd.com/read/28991063/dose-response-curves-for-intrathecal-bupivacaine-levobupivacaine-and-ropivacaine-given-for-labor-analgesia-in-nulliparous-women
#12
Warwick D Ngan Kee, Floria F Ng, Kim S Khaw, Shannon P Y Tang, Alison G P Koo
BACKGROUND AND OBJECTIVES: Bupivacaine, levobupivacaine, and ropivacaine are often given intrathecally for labor analgesia, but limited data are available for their dose-response properties in this context. The objective of this study was to describe the dose-response curves of these local anesthetics when given intrathecally for labor analgesia, to determine values for D50 (dose producing a 50% response) and to compare the calculated values of D50 for levobupivacaine and ropivacaine with those for bupivacaine...
October 4, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/28990828/radiologic-features-of-vascular-pulsatile-tinnitus-suggestion-of-optimal-diagnostic-image-workup-modalities
#13
Ah-Ra Lyu, Sung Jae Park, Dami Kim, Ho Yun Lee, Yong-Ho Park
OBJECTIVES: The aim of this study was to determine the optimal diagnostic workup modalities for vascular pulsatile tinnitus through analysis of clinical and radiologic findings. MATERIALS AND METHODS: A total of 49 patients diagnosed with vascular pulsatile tinnitus along with their medical records and radiologic findings were thoroughly reviewed. RESULTS: Of these patients, 84% had venous lesions. The jugular bulb variants (67%) were the most common venous lesions followed by sigmoid sinus variants (12%)...
October 9, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28985431/growth-rate-reduction-causes-a-decline-in-the-annual-incremental-trunk-growth-in-masting-fagus-crenata-trees
#14
Daisuke Kabeya, Yoshiyuki Inagaki, Kyotaro Noguchi, Qingmin Han
Tree trunk annual increments are markedly reduced in mast years. There are two hypotheses that could explain the mechanism for this phenomenon: (1) a reduction in the duration of growth due to switching the resource allocation from somatic growth to seed production; (2) reduction of growth rate due to resources being shared between somatic growth and reproduction simultaneously. In this study, we aimed to test these hypotheses in Fagus crenata  Blume from the point of view of resource allocation. The radial growth patterns in F...
June 28, 2017: Tree Physiology
https://www.readbyqxmd.com/read/28984118/intracerebral-hemorrhage-in-the-context-of-cerebral-amyloid-angiopathy-and-varied-time-of-onset-of-cerebral-venous-thrombosis-a-case-report
#15
Tadeusz A Mendel, Beata Błażejewska-Hyżorek, Grażyna M Szpak, Tomasz Stępień, Eliza Lewandowska, Sylwia Tarka, Iwona Kurkowska-Jastrzębska, Teresa Wierzba-Bobrowicz
In patients with cerebral venous thrombosis (CVT) the incidence of intracerebral hemorrhage (ICH) is estimated at about 37% and subarachnoid hemorrhage (SAH) at 1% of patients. A case with coincident occurrence of ICH, SAH and CVT in a patient with cerebral amyloid angiopathy (CAA) is reported. A 79-year-old woman was admitted to the Neurological Department after the occurrence of generalized seizures, the first in her life. On admission she was unconscious with right hemiparesis and deviation of eyes to the left...
2017: Folia Neuropathologica
https://www.readbyqxmd.com/read/28982515/robotic-total-pelvic-exenteration-with-intracorporeal-sigmoid-conduit-and-colostomy-step-by-step-technique
#16
Matthew J Maurice, Daniel Ramirez, Emre Gorgun, Georges-Pascal Haber
OBJECTIVE: To describe our technique for robotic total pelvic exenteration with intracorporeal sigmoid conduit and colostomy using the da Vinci Si robot. METHODS: Three 8-mm robotic ports and two 12-mm laparoscopic ports are placed in a "W" configuration, approximately 2-3 cm more cephalad than for radical prostatectomy (Fig. 1). The robot is docked between the legs with the patient in steep Trendelenburg. The ureters are dissected out from the iliac vessels to the rectovesical pouch, where they are clipped and transected...
July 2017: Urology
https://www.readbyqxmd.com/read/28976507/two-step-volume-phase-transition-mechanism-of-poly-n-vinylcaprolactam-hydrogel-online-tracked-by-two-dimensional-correlation-spectroscopy
#17
Gehong Su, Tao Zhou, Xifei Liu, Yulin Zhang
In this study, temperature-dependent FTIR spectroscopy in combination with the perturbation-correlation moving-window (PCMW2D) technique and generalized two-dimensional (2D) correlation analysis was applied to investigate the phase transition mechanism of poly(N-vinylcaprolactam) (PVCL) hydrogel upon heating. In the conventional 1D FTIR spectra, the gradual dehydration of C-H groups, as well as the gradual dissociation of hydrogen bonds between C[double bond, length as m-dash]O groups and water molecules, was observed during phase transition...
October 4, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28972374/effect-of-film-diffusion-on-the-ion-exchange-kinetics-of-a-tracer-ion-in-nafion-117-membrane-from-a-mixture-of-salt-solution
#18
Apurva N Naik, Chhavi Agarwal, Sanhita Chaudhury, Asok Goswami
Ion exchange kinetics of a tracer ion (Cs+&Ba2+) in presence of a bulk ion (Na+/H+) has been measured in Nafion-117 membrane for a range of concentration of NaCl/HNO3 using non-stationary radiotracer method. A systematic increase in the ion exchange rate and decrease in the partition coefficients of the tracer ions between membrane and solution have been observed with the increase in bulk ion concentration. The sigmoidal nature of experimental profiles indicates film diffusion controlled kinetics even for well stirred solutions...
October 3, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28972289/endoscopic-grading-of-myochosis-and-its-association-with-colonic-obstructive-symptoms
#19
Subhash Chandra, Adrian Holm, Konrad S Schulze
Prominent colonic mucosal folds are referred as myochosis. Myochosis results from shortening of taeniae from elastosis, squishing together of the sigmoid like an accordion, creating deep recesses between prominent folds.(1) These changes are often under-reported in endoscopy notes. Here, we report development of an endoscopic classification system for diagnosis, grading and reporting of myochosis. We also evaluated the obstructive nature of myochosis. This article is protected by copyright. All rights reserved...
October 3, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28969588/design-considerations-and-analysis-planning-of-a-phase-2a-proof-of-concept-study-in-rheumatoid-arthritis-in-the-presence-of-possible-non-monotonicity
#20
Feng Liu, Stephen J Walters, Steven A Julious
BACKGROUND: It is important to quantify the dose response for a drug in phase 2a clinical trials so the optimal doses can then be selected for subsequent late phase trials. In a phase 2a clinical trial of new lead drug being developed for the treatment of rheumatoid arthritis (RA), a U-shaped dose response curve was observed. In the light of this result further research was undertaken to design an efficient phase 2a proof of concept (PoC) trial for a follow-on compound using the lessons learnt from the lead compound...
October 2, 2017: BMC Medical Research Methodology
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