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Kyphoplasty

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https://www.readbyqxmd.com/read/29765210/percutaneous-kyphoplasty-combined-with-zoledronic-acid-infusion-in-the-treatment-of-osteoporotic-thoracolumbar-fractures-in-the-elderly
#1
Chen Shi, Mi Zhang, An-Yuan Cheng, Zi-Feng Huang
Objective: We studied the efficacy of zoledronic acid (ZOL) infusion on radiographic and clinical outcomes after percutaneous kyphoplasty (PKP) for elderly patients with osteoporotic thoracolumbar fractures (osteoporotic vertebral compression fractures [OVCFs]). Materials and methods: We retrospectively analyzed 95 elderly patients (age >65 years) with OVCF. All patients were followed up for 2 years. Thirty-two patients were treated with only once-yearly 5 mg ZOL infusion (ZOL group), 34 patients with only PKP (PKP group) and 29 patients received ZOL infusion 3 days after PKP (PKP+ZOL group)...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29734460/diagnostic-accuracy-of-fluoroscopy-radiography-and-computed-tomography-in-detecting-cement-leakage-in-kyphoplasty
#2
Hans-Georg Palm, Hans-Joachim Riesner, Patricia Lang, Madlen Haentzsch, Benedikt Friemert, Carsten Hackenbroch
PURPOSE:  Cement leakage is a typical complication of kyphoplasty for vertebral fractures. It is unclear if cement application intraoperatively can be improved by using other techniques of visualization and which kind of postoperative imaging should be recommended to detect cement extravasation accurately. OBJECTIVE:  To compare the rates of cement leakage detected by intraoperative fluoroscopy, postoperative radiography, and postoperative computed tomography (CT) in a retrospective study...
May 7, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29729780/mechanisms-of-and-adjuvants-for-bone-pain
#3
REVIEW
Nicholas Figura, Joshua Smith, Hsiang-Hsuan Michael Yu
Metastatic bone pain is a complex, poorly understood process. Understanding the unique mechanisms causing cancer-induced bone pain may lead to potential therapeutic targets. This article discusses the effects of osteoclast overstimulation within the tumor microenvironment; the role of inflammatory factors at the tumor-nociceptor interface; the development of structural instability, causing mechanical nerve damage; and, ultimately, the neuroplastic changes in the setting of sustained pain. Several adjuvant therapies are available to attenuate metastatic bone pain...
June 2018: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/29729455/the-5-item-modified-frailty-index-is-predictive-of-30-day-postoperative-complications-in-patients-undergoing-kyphoplasty-vertebral-augmentation
#4
Dale Segal, Jacob M Wilson, Christopher Staley, Keith W Michael
BACKGROUND: Vertebral compression fractures are the most common spine injury seen in elderly patients. Vertebral augmentation is considered a safe and effective treatment. The ability to predict outcomes based on comorbidities is lacking. The modified frailty index has been used to predict complications after orthopedic and surgical procedures. We hypothesized that despite a low rate of adverse outcomes, postoperative complications following kyphoplasty would be higher in frail patients...
May 2, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29707556/the-outcomes-of-percutaneous-kyphoplasty-in-treatment-of-the-secondary-osteoporotic-vertebral-compression-factures-a-case-control-study
#5
Ai-Min Wu, Xun-Lin Li, Xiao-Bin Li, Kai Zhang, Xiao-Jiang Sun, Chang-Qing Zhao, Shen Wang, Qi-Shan Huang, Yan Lin, Wen-Fei Ni, Xiang-Yang Wang, Jie Zhao
Background: To investigate the outcomes of using percutaneous kyphoplasty in the treatment of the secondary osteoporotic vertebral compression fractures. Methods: Eighty-one patients had the secondary single segmental osteoporotic vertebral compression fractures after the initial fractures and treated by percutaneous kyphoplasty were reviewed, 74 of them had minimum 2 years follow-up were included in this study. The 74 patients with primary osteoporotic vertebral compression fractures treated by percutaneous kyphoplasty at the same time period were matched as control group in 1:1 ratio...
March 2018: Annals of Translational Medicine
https://www.readbyqxmd.com/read/29704173/infection-following-percutaneous-vertebral-augmentation-with-polymethylmethacrylate
#6
Jae-Woo Park, Sang-Min Park, Hui Jong Lee, Choon-Ki Lee, Bong-Soon Chang, Hyoungmin Kim
Although the incidence of infection following vertebroplasty or kyphoplasty is rare, postoperative infection and cement augmentation in preexistent spondylitis can cause life-threatening complications in frail patients with notable comorbidities. In such cases, urgent culture and biopsy and the long-term use of proper antibiotics are necessary. PURPOSE: Infection following vertebral augmentation with polymethylmethacrylate (PMMA) is rare. We aimed to analyze 11 cases of pyogenic spondylitis and spondylodiscitis that occurred after vertebroplasty or kyphoplasty and to review similar cases in the literature...
April 27, 2018: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29703087/assessment-of-radiation-exposure-in-balloon-kyphoplasty-using-a-new-navigation-system
#7
Bin He, Shujun Xie, Jing Wang, Chao Xu, Yingdelong Mao, Shuogui Xu
STUDY DESIGN: Randomized controlled trials of conventional and laser-navigated technology techniques for balloon kyphoplasty were carried out. OBJECTIVE: To evaluate the effectiveness of a new laser navigation system in reducing the radiation dose in balloon kyphoplasty procedures. MATERIAL AND METHODS: Sixty-seven randomized controlled trials involving a total of 75 lumbar vertebrae were treated. Thirty-four vertebrae were treated by regular fluoroscopic imaging alone, and the other 41 vertebrae were treated using the new laser navigation system...
April 27, 2018: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/29702425/impact-of-frailty-on-complications-in-patients-with-thoracic-and-thoracolumbar-spinal-fracture
#8
Remi A Kessler, Rafael De la Garza Ramos, Taylor E Purvis, A Karim Ahmed, C Rory Goodwin, Daniel M Sciubba, Muhammad M Abd-El-Barr
OBJECTIVES: It is well-documented that geriatric patients are at risk for serious injuries after fracture due to pre-existing medical conditions, physical changes of aging, and medication effects. Frailty has been demonstrated to be a predictor of morbidity and mortality in inpatient head and neck surgery, and for surgical intervention for adult spinal deformity and degenerative spine disease. However, the impact of frailty on complications following thoracolumbar/thoracic fractures are unknown and has not been previously assessed in the literature, particularly in a nationwide setting...
April 9, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29699732/vertebral-fragility-fractures-vff-who-when-and-how-to-operate
#9
Opinder Sahota, Terence Ong, Khalid Salem
Vertebral Fragility Fractures (VFF) are common and lead to pain, long term disability and increased mortality. Most patients will have mild to moderate pain symptoms and can be managed conservatively. However, patients with severe pain who have minimal or no pain relief with potent analgesia, or who only achieve adequate pain relief with high doses of morphine based analgesia which results in significant adverse events, should be considered for vertebral augmentation. Ideally, for vertebral augmentation, patients should present within four months of the fracture (onset of acute pain) and have at least 3 weeks of failure of conservative treatment although early intervention may be more appropriate for hospitalised patients, who tend to be older, more frail and likely to be less tolerant to the adverse effects of conservative treatment...
April 22, 2018: Injury
https://www.readbyqxmd.com/read/29692935/percutaneous-injection-of-strontium-containing-hydroxyapatite-versus-polymethacrylate-plus-short-segment-pedicle-screw-fixation-for-traumatic-a2-and-a3-ao-type-fractures-in-adults
#10
Panagiotis Korovessis, Eva Mpountogianni, Vasileios Syrimpeis, Andreas Baikousis, Vasileios Tsekouras
Introduction: Polymethacrylate (PMMA) is commonly used in vertebroplasty and balloon kyphoplasty, but its use has been associated with complications. This study tests three hypotheses: (1) whether strontium hydroxyapatite (Sr-HA) is equivalent to PMMA for restoring thoracolumbar vertebral body fractures, (2) whether the incidence of PMMA leakage is similar to that of Sr-HA leakage, and (3) whether Sr-HAis is resorbed and substituted by new vertebral bone. Materials and Methods: Two age- and sex-matched groups received short percutaneous pedicle screw fixation plus PEEK implant (Kiva, VCF Treatment System, Benvenue Medical, Santa Clara, CA, USA) filled with either Sr-HA (Group A) or PMMA (Group B) after A2- and A3/AO-type thoracolumbar vertebral body fractures...
2018: Advances in Orthopedics
https://www.readbyqxmd.com/read/29679136/the-pedicle-instrumentation-and-percutaneous-elevation-pi-pe-a-new-cementless-surgical-technique-in-type-a-post-traumatic-vertebral-fractures
#11
Andrea Piazzolla, Giuseppe Solarino, Davide Bizzoca, Claudia Parato, Gaetano Monteleone, Franca Dicuonzo, Biagio Moretti
PURPOSE: To investigate if bone substitutes are strictly necessary to restore the vertebral body height and improve the clinical outcome, in patients with thoracolumbar or lumbar AO type A post-traumatic vertebral fractures, managed with balloon kyphoplasty combined with posterior screw and rod system. METHODS: 105 patients with post-traumatic thoracolumbar spine fracture were recruited. At baseline, the patients underwent a CT and an MRI of the spine. Clinical evaluation was performed, using the Visual Analog Scale (VAS) and the Oswestry Disability Index (ODI), at baseline, 48 h after surgery, at 3-month follow-up (FU), 6-month FU, 48 h after the instrumentation removal and at 24-month FU...
April 20, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29678706/mid-term-clinical-and-radiological-outcomes-after-kyphoplasty-in-the-treatment-of-thoracolumbar-traumatic-vertebral-compression-fractures
#12
Michael Grelat, Rachid Madkouri, Pierre-Olivier Comby, Elie Fahed, Brivael Lemogne, Pierre Thouant
OBJECTIVE: The management of thoracolumbar post-traumatic compression fractures widely varies among centers, and there is no real consensus. The objective of our retrospective study was to detect the progression of vertebral kyphosis in non-osteoporotic patients treated by balloon kyphoplasty (KPB) who presented recent compression fractures of the thoracolumbar region. MATERIALS AND METHODS: From 2007 to 2011, we focused in this retrospective study on the vertebral and regional kyphosis evolution in 77 patients treated by KPB for compression vertebral fractures (Magerl A)...
April 17, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29677554/glass-polyalkenoate-cement-an-alternative-material-for-kyphoplasty-in-osteoporotic-vertebral-compression-fractures-an-ex-vivo-study
#13
Tim Leschinger, Karsten Engel, Gert Peter Brüggemann, Viktoria Dederer, Wolfram Friedrich Neiss, Max Joseph Scheyerer, Lars Peter Müller, Kilian Wegmann
Adjacent vertebral body fracture is described as a risk after vertebroplasty and kyphoplasty. It may be true that this phenomenon is caused precisely because of the frequently used polymethylmethacrylate cement (PMMA), which shows a higher level of stiffness than bone material and may ultimately lead to shifting stress levels within the entire spine. The goal of the present study was to evaluate and compare the pressure distribution in the endplate of human vertebrae after kyphoplasty with PMMA and aluminum-free glass-polyalkenoate cement (gpc)...
March 21, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29667142/pulmonary-cement-embolism-is-not-associated-with-the-cause-of-death-in-a-post-mortem-cohort-of-cement-augmented-interventions-in-the-spine
#14
Sebastian Butscheidt, Tim Rolvien, Jakob Ritter, Axel Heinemann, Hermann Vogel, Michael Amling, Klaus Püschel
PURPOSE: Complications of cement-augmented interventions (e.g., kyphoplasty) in the spine include local cement leakage and pulmonary cement embolisms (PCE). This study was conducted to determine their extent in a unique post-mortem cohort. METHODS: Retrospective analysis of post-mortem whole-body CT scans and review of autopsy results in 29 consecutive cases with cement-augmented interventions in the spine. PCE findings were graded based on cement deposits: grade 0 (no PCE), grade 1 (1-3 PCE), grade 2 (4-6 PCE), and grade 3 (> 6 or branch-shaped PCE)...
April 17, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29662772/editorial-for-the-clinical-paper-therapeutic-effects-analysis-of-percutaneous-kyphoplasty-for-osteoporotic-vertebral-compression-fractures-a-multicentre-study-huilin-yang-et-al
#15
EDITORIAL
https://www.readbyqxmd.com/read/29662771/therapeutic-effects-analysis-of-percutaneous-kyphoplasty-for-osteoporotic-vertebral-compression-fractures-a-multicentre-study
#16
Huilin Yang, Liang Chen, Zhaomin Zheng, Guoyong Yin, William W Lu, Genlin Wang, Xuesong Zhu, Dechun Geng, Jun Zhou, Bin Meng, Haiqing Mao, Tao Liu, Junjie Niu, Tiansi Tang, Jun Zou
Background: Percutaneous kyphoplasty (PKP), a minimally invasive treatment, has been widely used for osteoporotic vertebral compression fractures (OVCFs). Objective: To retrospectively analyse the therapeutic effects of PKP using a series of key techniques in a multicentre study. Methods: From May 2000 to December 2016, PKP was performed using a series of key techniques (puncture, reduction, and perfusion techniques) for the treatment of 4532 OVCF patients...
October 2017: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29618171/percutaneous-vertebroplasty-for-osteoporotic-vertebral-compression-fracture
#17
REVIEW
Rachelle Buchbinder, Renea V Johnston, Kobi J Rischin, Joanne Homik, C Allyson Jones, Kamran Golmohammadi, David F Kallmes
BACKGROUND: Percutaneous vertebroplasty remains widely used to treat osteoporotic vertebral fractures although our 2015 Cochrane review did not support its role in routine practice. OBJECTIVES: To update the available evidence of the benefits and harms of vertebroplasty for treatment of osteoporotic vertebral fractures. SEARCH METHODS: We updated the search of CENTRAL, MEDLINE and Embase and trial registries to 15 November 2017. SELECTION CRITERIA: We included randomised and quasi-randomised controlled trials (RCTs) of adults with painful osteoporotic vertebral fractures, comparing vertebroplasty with placebo (sham), usual care, or another intervention...
April 4, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29565962/re-factors-affecting-delayed-union-of-vertebral-fractures-following-percutaneous-kyphoplasty
#18
XiaoFeng Liu, HuiMing Wu
No abstract text is available yet for this article.
March 2018: Pain Physician
https://www.readbyqxmd.com/read/29561435/comparison-of-high-and-low-viscosity-cement-in-the-treatment-of-vertebral-compression-fractures-a-systematic-review-and-meta-analysis
#19
Zhao-Fei Zhang, He Huang, Shuai Chen, Dong-Hua Liu, Yong-Hui Feng, Chun-Liang Xie, Feng Jiao
BACKGROUND: High-viscosity cement (HVC) has been gradually applied in percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP). Although HVC has been reported to reduce cement leakage, different opinions exist. To assess the complications of HVC in cement leakage in the treatment of vertebral compression fractures and to evaluate the clinical effect of HVC compared with low-viscosity cement (LVC). METHODS: EMBASE, PubMed, Science Direct, Google Scholar and Cochrane Library databases were comprehensively searched from their inception to August 2017...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29553284/quantitative-t2-mapping-shows-increased-degeneration-in-adjacent-intervertebral-discs-following-kyphoplasty
#20
Milena L Pachowsky, Arnd Kleyer, Lisa Wagner, Andreas Langenbach, David Simon, Rolf Janka, Matthias May, Goetz H Welsch
Objective A minimally invasive treatment of osteoporotic and nonosteoporotic thoracic and lumbar spine fractures is cement augmentation (kyphoplasty). Little is known about the impact on adjacent intervertebral discs. A quantitative magnetic resonance imaging (MRI) approach in addition to morphological MRI is desirable to evaluate changes in the intervertebral disc. Our study aims to evaluate the feasibility of T2 mapping for the detection of subtle changes in the intervertebral discs in spines after kyphoplasty...
March 1, 2018: Cartilage
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