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https://www.readbyqxmd.com/read/28228791/two-cases-of-pregnancy-and-lactation-associated-osteoporosis-successfully-treated-with-denosumab
#1
Ariel Sánchez, María Belén Zanchetta, Karina Danilowicz
Case 1. A 35-year-old woman in the 8(th) month of her first pregnancy suffered acute lumbar pain that persisted for 4 months. In the 5(th) month postpartum an acute increase in the low back pain led to a MRI which showed recent deformity in L1 and deformities of undetermined time of evolution in L2, L4, and L5. Laboratory evaluation did not reveal metabolic derangements. She had low bone mineral density (BMD, DXA) and severe deterioration of the microarchitecture of distal appendicular bone (HR-pQCT). Kyphoplasty of all 4 vertebrae was performed in 2 stages, and treatment with subcutaneous denosumab, 60 mg every 6 months, was begun...
September 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/28207616/percutaneous-kyphoplasty-in-the-treatment-of-osteoblastic-related-spinal-metastases
#2
Hong-Tao Zhang, Guang-Dong Chen, Hui-Lin Yang, Zong-Ping Luo
STUDY DESIGN: A retrospective study. OBJECTIVE: To evaluate the feasibility, efficacy, and safety of percutaneous kyphoplasty (PKP) for the treatment of painful osteoblastic-related spinal metastases unresponsive to conservative treatments. SUMMARY OF BACKGROUND DATA: PKP represents a powerful tool in the management of oncology patients who suffer from painful osteolytic spinal lesions. However, to our knowledge, there have been no reports on the role of PKP in the treatment of osteoblastic metastatic spinal lesions...
March 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28192270/risk-factors-for-cement-leakage-after-vertebroplasty-or-kyphoplasty-a-meta-analysis-of-published-evidence
#3
REVIEW
Yi Zhan, Jianzhong Jiang, Haifen Liao, Haitao Tan, Keqin Yang
BACKGROUND: Cement leakage is the most common complication of vertebroplasty and kyphoplasty. So far, the reported risk factors remain conflicting due to limited data and lack of uniform measurement and evaluation. Here, we aimed to perform a systematic review and meta-analysis of potential risk factors for cement leakage after vertebroplasty or kyphoplasty. METHODS: Relevant literature was retrieved using PubMed, EMBASE, Cochrane Controlled Trial Register and MEDLINE with no language restriction, supplemented by a hand-search of the reference lists of selected articles...
February 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28175477/167%C3%A2-reducing-radiation-an-order-of-magnitude-during-fluoroscopic-guided-kyphoplasty
#4
Isaac O Karikari, Chris Brown, D Gregg Anderson, Debbie Chi
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28158161/factors-affecting-delayed-union-of-vertebral-fractures-following-percutaneous-kyphoplasty
#5
Xin He, YiBin Meng, YunFei Huang, DingJun Hao, QiNing Wu, JiJun Liu
BACKGROUND: Although percutaneous kyphoplasty (PKP) could achieve rapid pain relief for the elderly with osteoporotic vertebral compression fracture (OVCF), some patients still had risks of suffering vertebrae delayed union which led to persisting pain and vertebral collapse. Preventing the delayed vertebral union could reduce the further morbidities and medical costs for patients with OVCF after PKP. OBJECTIVES: To explore the factors involved in delayed vertebral union after PKP in patients with OVCF...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28120768/-use-of-pedicle-percutaneous-cemented-screws-in-the-management-of-patients-with-poor-bone-stock
#6
S Pesenti, T Graillon, N Mansouri, T Adetchessi, P Tropiano, B Blondel, S Fuentes
INTRODUCTION: Management of patients with poor bone stock remains difficult due to the risks of mechanical complications such as screws pullouts. At the same time, development of minimal invasive spinal techniques using a percutaneous approach is greatly adapted to these fragile patients with a reduction in operative time and complications. The aim of this study was to report our experience with cemented percutaneous screws in the management of patients with a poor bone stock. METHODS: Thirty-five patients were included in this retrospective study...
December 2016: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28120057/reconstruction-of-vertebral-body-after-radiofrequency-ablation-and-augmentation-in-dorsolumbar-metastatic-vertebral-fracture-analysis-of-clinical-and-radiological-outcome-in-a-clinical-series-of-18-patients
#7
Rosario Maugeri, Francesca Graziano, Luigi Basile, Carlo Gulì, Antonella Giugno, Giuseppe Roberto Giammalva, Massimiliano Visocchi, Domenico Gerardo Iacopino
BACKGROUND: Painful spinal metastases usually occur in malignant neoplastic disease. Treatment for bone metastases has been largely conservative, and it includes the use of high doses of analgesics, radiotherapy, chemotherapy, hormone therapy, and bisphosphonates; however, results are sometimes transient and ineffective. In the presence of neurological involvement a surgical strategy should be considered. Recently, percutaneous procedures such as radiofrequency ablation, vertebroplasty, and kyphoplasty have been introduced as palliative techniques to treat painful vertebral metastases [3, 11, 25]...
2017: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/28107240/an-in-vitro-evaluation-of-fracture-reduction-achieved-by-inflatable-bone-tamps-under-simulated-physiological-load
#8
Michael Gordon, Walter C Peppelman, William Beutler, Damien OʼHalloran, Suresh R Chinthakunta, Brandon Bucklen
STUDY DESIGN: An in vitro biomechanical study. OBJECTIVE: To determine the fracture reduction achieved by a novel inflatable bone tamp under simulated physiological load. SUMMARY OF BACKGROUND DATA: Previous biomechanical studies have showed that kyphoplasty allows near-total restoration of lost vertebral height in unloaded conditions and partial height restoration under simulated physiological loads. Clinically, loss of reduction has been observed after bone tamp deflation, before cement injection...
February 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28102450/hidden-blood-loss-and-the-influential-factors-after-percutaneous-kyphoplasty-surgery
#9
Yao-Sen Wu, Hui Zhang, Wen-Hao Zheng, Zhen-Hua Feng, Ze-Xin Chen, Yan Lin
PURPOSE: Percutaneous kyphoplasty (PKP) is a minimally invasive procedure for the treatment of osteoporotic vertebral compression fractures (OVCFs). It is generally considered that there is little blood loss during the surgery. However, a significant perioperative hidden blood loss (HBL) is neglected. This study was to examine the amount of HBL and determine the influential factors during PKP. METHODS: From January 2015 to January 2016, 115 patients with OVCFs who were scheduled to have a PKP were enrolled in this study...
January 19, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28101655/percutaneous-vertebral-augmentation-in-fragility-fractures-indications-and-limitations
#10
O Gonschorek, S Hauck, T Weiß, V Bühren
INTRODUCTION: There is still no general consensus about the management of osteoporotic vertebral fractures. Recommendations depend on type of fracture, grade of instability, bone quality, and general conditions of the patient. Spontaneous fractures may be considered to be treated different compared to cases with high-velocity trauma. METHODS: According to the DVO, patients without trauma should first be treated conservatively. However, there is no more strict time protocol of 3 or 6 week conservative treatment before operations may be indicated...
January 18, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28093624/osteoporotic-vertebral-body-fractures-of-the-thoracolumbar-spine-indications-and-techniques-of-a-360%C3%A2-stabilization
#11
Ulrich Spiegl, J-S Jarvers, C-E Heyde, C Josten
Unstable vertebral body fragility fractures of the thoracolumbar spine can occur with or without relevant trauma. Initially, a standardized diagnostic algorithm including magnetic resonance tomography is recommended to detect accompanied further vertebral body fractures, to interpret the individual fracture stability, and to screen for relevant traumatic intervertebral disc lesions. Aim of the therapy is to assure fast mobilization and to maintain spinal alignment. Unstable fracture morphology is defined by vertebral body fractures including a relevant defect of the posterior vertebral cortex as well as type B or C fractures...
January 16, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28093431/which-is-best-for-osteoporotic-vertebral-compression-fractures-balloon-kyphoplasty-percutaneous-vertebroplasty-or-non-surgical-treatment-a-study-protocol-for-a-bayesian-network-meta-analysis
#12
Shun-Li Kan, Zhi-Fang Yuan, Ling-Xiao Chen, Jing-Cheng Sun, Guang-Zhi Ning, Shi-Qing Feng
INTRODUCTION: Osteoporotic vertebral compression fractures (OVCFs) commonly cause both acute and chronic back pain, substantial spinal deformity, functional disability and decreased quality of life and increase the risk of future vertebral fractures and mortality. Percutaneous vertebroplasty (PVP), balloon kyphoplasty (BK) and non-surgical treatment (NST) are mostly used for the treatment of OVCFs. However, which treatment is preferred is unknown. The purpose of this study is to comprehensively review the literature and ascertain the relative efficacy and safety of BK, PVP and NST for patients with OVCFs using a Bayesian network meta-analysis...
January 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/28087450/item-response-theory-analysis-to-evaluate-reliability-and-minimal-clinically-important-change-of-the-roland-morris-disability-questionnaire-in-patients-with-severe-disability-due-to-back-pain-from-vertebral-compression-fractures
#13
Minji K Lee, Kathleen J Yost, Jennifer S McDonald, Ryne W Dougherty, Roanna L Vine, David F Kallmes
BACKGROUND CONTEXT: The majority of validation done on the Roland-Morris Disability Questionnaire (RMDQ) has been in patients with mild or moderate low disability. There is paucity of research focusing on the psychometric quality of the RMDQ in patients with severe disability. PURPOSE: To evaluate the psychometric quality of the RMDQ in patients with severe disability. STUDY DESIGN/SETTING: Observational clinical study SAMPLE: The sample consisted of 214 patients with painful vertebral compression fractures who underwent vertebroplasty or kyphoplasty...
January 10, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28081331/segmental-epidural-anesthesia-for-percutaneous-kyphoplasty-comparison-with-general-anesthesia
#14
Alparslan Apan, Özgün Cuvaş Apan, Emine Arzu Köse
BACKGROUND/AIM: This is a feasibility study evaluating whether segmental epidural anesthesia is an alternative anesthetic approach to general anesthesia for percutaneous kyphoplasty. MATERIALS AND METHODS: After ethics committee approval was obtained, 52 ASA class I-III patients scheduled for elective, single-level percutaneous kyphoplasty were recruited. The patients were divided into two equal groups. In Group E (Group Epidural) segmental epidural anesthesia was performed using the loss of resistance technique with saline...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28072794/does-percutaneous-vertebroplasty-or-balloon-kyphoplasty-for-osteoporotic-vertebral-compression-fractures-increase-the-incidence-of-new-vertebral-fractures-a-meta-analysis
#15
Hui Zhang, Caiyuan Xu, Tongxing Zhang, Zhongyu Gao, Tao Zhang
BACKGROUND: Because of an aging population,osteoporotic vertebral fractures are becoming more frequent.Conservative therapy was considered the gold standard for treating osteoporotic vertebral compression fractures (OVCFs) in the past. Percutaneous vertebroplasty (PVP) or balloon kyphoplasty (BKP) as minimally invasive techniques are new treatments that are widely used for painful OVCFs. However, an increase in new vertebral compression fractures at non-treated levels following augmentation is of concern...
January 2017: Pain Physician
https://www.readbyqxmd.com/read/28041324/frequency-of-symptomatic-vertebral-body-compression-fractures-requiring-intervention-following-single-fraction-stereotactic-radiosurgery-for-spinal-metastases
#16
Michael S Virk, James E Han, Anne S Reiner, Lily A McLaughlin, Daniel M Sciubba, Eric Lis, Yoshiya Yamada, Mark Bilsky, Ilya Laufer
OBJECTIVE The purpose of this study was to determine the rate of symptomatic vertebral body compression fractures (VCFs) requiring kyphoplasty or surgery in patients treated with 24-Gy single-fraction stereotactic radiosurgery (SRS). METHODS This retrospective analysis included all patients who had been treated with 24-Gy, single-fraction, image-guided intensity-modulated radiation therapy for histologically confirmed solid tumor metastases over an 8-year period (2005-2013) at Memorial Sloan Kettering Cancer Center...
January 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28035907/comparison-of-radiofrequency-kyphoplasty-and-balloon-kyphoplasty-in-combination-with-posterior-fixation-for-the-treatment-of-vertebral-fractures
#17
R Bornemann, T R Jansen, L A Otten, K Sander, D C Wirtz, R Pflugmacher
BACKGROUND: In case of complex vertebral fractures, posterior fixation is often required for correction of deformity and instability. Fixation is commonly supported by balloon kyphoplasty (BKP) anterior. A development of BKP is radiofrequency-targeted vertebral augmentation (RF-TVA), which leads to comparable results for augmentation and pain relief. OBJECTIVE: This prospective study evaluates the outcome of posterior fixation combined with RF-TVA or BKP, respectively...
December 23, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28009343/interaction-of-radiation-therapy-and-radiofrequency-kyphoplasty-in-the-treatment-of-myeloma-patients
#18
Rahel Bornemann, Philip P Roessler, Tom R Jansen, Yorck Rommelspacher, Kirsten Sander, Dieter C Wirtz, Robert Pflugmacher, Sönke P Frey
BACKGROUND: 30% of myeloma patients suffer from vertebral compression fractures (VCF). Consequently, augmentation often becomes inevitable to prevent further problems. This study evaluated the interaction of radiation therapy (RT) and radiofrequency kyphoplasty (RFK) in the treatment of myeloma associated VCF. METHODS: Eighty-six myeloma patients with VCF were treated with RFK followed by radiation therapy (RFK group) or vice versa (RT group). Visual analgoue scale (VAS), Oswestry-Disability-Index (ODI), vertebral height and kyphosis angle were assessed preoperatively, 3-4 days, 3 and 6 months postoperatively...
December 16, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/27975350/diagnosis-of-neuropathic-components-in-patients-with-back-pain-before-and-after-surgery
#19
Y-J Lee, E M W Koch, J B Breidebach, R Bornemann, D C Wirtz, R Pflugmacher
Background: The perception of back pain subjective is hard for physicians to measure. For this reason, questionnaires are an important instrument to evaluate the pain 1. The main point of this study was to verify differentiation of pain symptoms in patients with different pain mechanisms. The most important parameter was the PainDetect questionnaire, which can differentiate between nociceptive and neuropathic pain. Additional parameters were measured before and after surgery to characterise pain symptoms in detail...
December 2016: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/27925638/biomechanical-analysis-of-intervertebral-cement-extravasation-in-vertebral-motion-segments
#20
Trevor C Wahlquist, John J Lee, Alexander Brunfeldt, Geoffrey T Burns, Rakesh D Patel, Gregory P Graziano
Kyphoplasty is a therapeutic option for pain relief in the setting of compression fractures. Cement extravasation into adjacent disks is a common occurrence. The biomechanical and clinical consequences of cement in the disks currently are unknown. This study investigated the biomechanical effects of cement extravasation into the intervertebral disk in a human cadaveric model. Seven thoracolumbar and lumbar embalmed human cadaveric motion segments were evaluated in axial rotation, right and left lateral bending, and flexion and extension...
December 7, 2016: Orthopedics
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