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Abdominoperineal resection

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https://www.readbyqxmd.com/read/28217301/risk-factors-for-perineal-wound-infection-after-abdominoperineal-resection-of-advanced-lower-rectal-cancer
#1
Takatoshi Nakamura, Takeo Sato, Kazushige Hayakawa, Yoko Takayama, Masanori Naito, Takahiro Yamanashi, Atsuko Tsutsui, Hirohisa Miura, Masahiko Watanabe
PURPOSE: Abdominoperineal resection (APR) of advanced lower rectal cancer carries a high incidence of perineal wound infection. The aim of this study was to retrospectively evaluate risk factors for perineal wound infection after APR. METHODS: The study group comprised 154 patients who underwent APR for advanced lower rectal cancer in our department from January 1990 through December 2012. The following 15 variables were studied as potential risk factors for perineal wound infection: sex, age, body-mass index, American Society of Anesthesiologists score, diabetes mellitus, preoperative albumin level, preoperative hemoglobin level, neoadjuvant chemoradiotherapy(NCRT), surgical procedure (open surgery vs...
March 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28212258/factors-influencing-difficulty-of-laparoscopic-abdominoperineal-resection-for-ultra-low-rectal-cancer
#2
Qiken Li, Dechuan Li, Lai Jiang, Pengnian Qiu, Zhixuan Fu, Lilong Tang, Weiping Chen
PURPOSE: Our current study was conducted to identify patients' anatomic, pathologic, and clinical factors to predict difficulty of performing laparoscopic abdominoperineal resection for ultra-low rectal cancer. MATERIALS AND METHODS: Records of 117 consecutive patients with rectal cancer 2 to 5 cm from the anal verge were retrospectively reviewed. Using univariate and multivariate linear or logistic regression models, standardized operative time and blood loss, as well as postoperative morbidity were utilized as endpoints to screen patients' multiple variables to predict operative difficulty...
February 20, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28206927/omental-pedicle-flap-does-not-decrease-the-incidence-of-bowel-obstruction-after-abdominoperineal-resection
#3
Kunal Kochar, Slawomir Marecik, Leela M Prasad, John Park
No abstract text is available yet for this article.
November 1, 2016: American Surgeon
https://www.readbyqxmd.com/read/28197206/survival-after-abdominoperineal-and-sphincter-preserving-resection-in-nonmetastatic-rectal-cancer-a-population-based-time-trend-and-propensity-score-matched-seer-analysis
#4
Rene Warschkow, Sabrina M Ebinger, Walter Brunner, Bruno M Schmied, Lukas Marti
Background. Abdominoperineal resection (APR) has been associated with impaired survival in nonmetastatic rectal cancer patients. It is unclear whether this adverse outcome is due to the surgical procedure itself or is a consequence of tumor-related characteristics. Study Design. Patients were identified from the Surveillance, Epidemiology, and End Results database. The impact of APR compared to coloanal anastomosis (CAA) on survival was assessed by Cox regression and propensity-score matching. Results. In 36,488 patients with rectal cancer resection, the APR rate declined from 31...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28171845/a-first-reported-case-of-metastatic-anorectal-amelanotic-melanoma-with-a-marked-response-to-anti-pd-1-antibody-nivolumab-a-case-report
#5
Katsuji Tokuhara, Kazuyoshi Nakatani, Hirotsugu Tanimura, Kazuhiko Yoshioka, Takahiro Kiyohara, Masanori Kon
INTRODUCTION: Anorectal amelanotic melanoma (AAMM) is a rare disease with poor prognosis. A standard treatment strategy for AAMM has not been established. PRESENTATION OF CASE: We report a case of successful treatment of AAMM with nivolumab. A 67-year-old man was referred for colonoscopy which revealed type I tumor in the rectum. AAMM was diagnosed with immunostaining histopathological biopsy findings. Enhanced computed tomography (ECT) revealed the rectal tumor without distant organ metastasis...
January 23, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28133313/-a-case-of-advanced-rectal-cancer-resulting-in-a-pathologically-complete-response-after-neoadjuvant-chemotherapy
#6
Takayuki Minoji, Kohei Murata, Tomohiro Kitahara, Shu Okamura, Yoichiro Nushijima, Rie Hamano, Tetsu Yanagisawa, Nariaki Fukuchi, Chikara Ebisui, Hideoki Yokouchi, Masakatsu Kinuta, Kazuhito Ohishi
A 61-years-old man was admitted to our hospital because of abdominal pain. Colonoscopy revealed a type 2 tumor in the rectum, which was diagnosed as low differentiated adenocarcinoma. At least 8 abdominal lymph adenopathies were enhanced on contrast-enhanced CT. We diagnosed stage cT3N2H0M0P0, cStage III b. Because of the risk of a poor prognosis, we tried neoadjuvant chemotherapy for the purpose of down staging. A CRT was prevented by Clostridium difficile enteritis, but we completed 80% of the regimen. Laparoscopic abdominoperineal resection was performed after 4 months of chemotherapy...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133302/-two-cases-of-locally-recurrent-rectal-cancer-after-intersphincteric-resection-that-were-controlled-with-a-combination-of-chemoradiotherapy-and-abdominoperineal-resection
#7
Yasuhiro Komatsu, Hitoshi Idani, Kazutaka Takahashi, Naoki Mimura, Toshihiro Ogawa, Soichiro Miyake, Michihiro Ishida, Daisuke Satoh, Yasuhiro Choda, Daisuke Sumitani, Masao Harano, Hiroyoshi Matsukawa, Yasutomo Ojima, Shigehiro Shiozaki, Masazumi Okajima
We report 2 cases of locally recurrent rectal cancer after intersphincteric resection(ISR)that were controlled with a combination of chemoradiotherapy and abdominoperineal resection(APR). In Case 1, we performed preoperative chemoradiotherapy( TS-1 plus RT 45 Gy)and APR for the local recurrence of ISR. On pathology, viable neoplastic cells were noted. In Case 2, we performed preoperative chemotherapy(Bmab plus mFOLFOX6)and APR for the local recurrence of ISR. On pathology, no viable neoplastic cells were noted...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133299/-laparoscopic-lateral-lymph-node-dissection-for-rectal-cancer-with-lateral-lymph-node-metastasis-a-case-report
#8
Hiroyuki Jin, Hajime Morohashi, Kentaro Sato, Satoko Umetsu, Tatsuya Yoshida, Yusuke Wakasa, Daichi Ichinohe, Hiroshi Ogasawara, Tatsuya Hasebe, Takuya Miura, Yoshiyuki Sakamoto, Kenichi Hakamada
BACKGROUND: Lateral lymph node dissection(LLND)for locally advanced lower rectal cancer is the standard treatment procedure in Japan. We performed LLND with an extraperitoneal approach. Recently, we introduced laparoscopic surgery for locally advanced rectal cancer and laparoscopic LLND. We performed laparoscopic LLND in a patient havinglower rectal cancer with lateral lymph node metastasis that was detected via preoperative imaging. CASE PRESENTATION: The patient was a woman in her 50s who experienced melena and visited a physician...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133295/-a-systematic-analysis-of-oncogene-and-tumor-suppressor-genes-for-panitumumab-resistant-rectal-cancer-with-wild-ras-gene-a-case-report
#9
Yosuke Tajima, Yoshifumi Shimada, Ryoma Yagi, Takuma Okamura, Masato Nakano, Hitoshi Kameyama, Hitoshi Nogami, Satoshi Maruyama, Yasumasa Takii, Kohei Miura, Hiroshi Ichikawa, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Toshifumi Wakai
A 58-year-old man was admitted with the complaint of bloody stools. Colonoscopy and computed tomography revealed a rectal cancer with a liver metastasis and multiple lung metastases. After administering a regimen comprising 3 courses of XELOX plus bevacizumab chemotherapy, the sizes of the primary and metastatic lesions decreased remarkably. Abdominoperineal resection was performed for local control of the cancer; the specimen from the initial tumor was found to be KRAS wild type. After 14 courses of XELOX chemotherapy, brain metastases were detected...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133250/-a-successful-case-of-conversion-therapy-after-chemotherapy-for-advanced-rectal-cancer-with-inguinal-lymph-node-metastasis
#10
Jun Sato, Hideaki Karasawa, Shimpei Maeda, Shinobu Ohnuma, Kazuhiro Watanabe, Munenori Nagao, Tomoya Abe, Hiroaki Musha, Fuyuhiko Motoi, Takeshi Naitoh, Michiaki Unno
A70-year-old man was diagnosed with lower rectal cancer with right inguinal lymph node metastasis. Surgical resection was not suitable for this patient. Chemotherapy(IRIS plus bevacizumab followed by XELOX plus bevacizumab)was administered for 16 months. After the chemotherapy, the rectal tumor and lymph node swelling were significantly reduced and distant metastasis was not observed on CT scans. Therefore, the tumor was considered to be resectable and abdominoperineal resection of the rectum with lymph node dissection was performed...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133143/-use-of-a-posterior-thigh-flap-with-the-gluteus-maximus-for-perineal-reconstruction-a-case-of-fournier-s-gangrene-with-rectal-cancer
#11
Hironori Tanaka, Nobuaki Suzuki, Shinobu Tomochika, Yuka Inoue, Taichi Kuwahara, Kazuhiko Sakamoto, Shigeru Takeda, Tomio Ueno, Shigeru Yamamoto, Tomoko Okita, Sho Yoshimoto, Shigefumi Yoshino, Shoichi Hazama, Masahiko Mutou, Hiroaki Nagano
We present a case of Fournier's gangrene secondary to rectal cancer that was managed with perineal reconstruction using a posterior thigh flap after debridement and tumor resection. A 67-year-old man was admitted with disturbed consciousness as well as hip and right thigh pain. His perineal and gluteal skin was necrotic. CT revealed subcutaneous emphysema that had spread from the rectum to the gluteal region and right thigh. We diagnosed him with Fournier's gangrene, and then removed the necrotic tissue and constructed a sigmoidostomy...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133112/-a-case-of-malignant-anorectal-melanoma-with-laparoscopic-abdominoperineal-resection
#12
Ryuichi Kuwahara, Yoshinori Kagawa, Yasuo Oneda, Tomo Ishida, Yoshihiro Morimoto, Yasuhumi Sato, Atsushi Naito, Kohei Murakami, Yoshiteru Katsura, Yoshiaki Ohmura, Atsushi Takeno, Yutaka Takeda, Takeshi Kato, Shigeyuki Tamura
A 69-year-old man with anemia underwent colonoscopy. Colonoscopy showed a black tumor, 2 cm from the anal verge. The biopsy specimen revealed malignant melanoma, which was preoperatively diagnosed as T1(SM), N0, M0, Stage I . We performed laparoscopic abdominoperineal resection. The tissue type and diagnosis were malignant melanoma, pT1b(10 mm), pN0, pM0, ly0, v0, pDM0, pPM0, pRM0, pStage I b, according to the Colon Cancer Handling Terms, 8th edition). The patient did not receive adjuvant chemotherapy. However, he survived postoperatively for 9 months, with no sign of recurrence...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133109/-four-cases-of-colorectal-cancer-with-para-aortic-lymph-node-metastases-successfully-resected-resulting-in-long-term-survival
#13
Yudai Yamamoto, Makoto Aoki, Keisuke Nakao, Kenji Shitara, Tetsuji Hayashi, Hiroyuki Fukunari, Gen Watanabe, Yoichi Ajioka
We encountered 4 cases of colorectal cancer with para-aortic lymph node(LN)metastases.Para -aortic LN dissection was performed after the diagnosis of solitary LN metastases.Case 1: A 69-year-old woman was diagnosed with ascending colon cancer.She underwent right hemicolectomy with D3 LN dissection.After 1 year and 3 months, tumor marker levels(CEA) were elevated, and para-aortic LN metastases were detected on CT.She was administered FOLFOX.After 1 year, para-aortic LN dissection was performed.She is doing well without any recurrence for 8 years and 9 months...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133087/-a-case-of-carcinoma-associated-with-an-anal-fistula-repaired-using-a-hatchet-flap-after-neoadjuvant-chemoradiotherapy
#14
Masatoshi Kuroda, Eiji Ikeda, Nobuji Yokoyama, Masaichi Kenmotsu, Shoji Takagi, Toshihisa Yamano
The patient was a 53-year-old man who complained of perianal pain. He had a 20-year history of an anal fistula. There was a 10 cm tumor with mucin-like discharge on the left side of the anus. His CEA level was high, at 7.3 ng/mL, and T2-weighted MRI revealed a multilocular cystic tumor with high signal intensity. The second biopsy result indicated mucinous adenocarcinoma. We performed neoadjuvant chemoradiotherapy. The chemotherapy regimen was TS-1 with radiation therapy, along with 4-port irradiation(50.4 Gy)of the primary tumor, located at the interior of the pelvis and inguinal lymph nodes...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28133076/-a-case-report-a-case-of-a-rapidly-growing-anal-canal-origin-malignant-melanoma
#15
Teruyuki Kobayashi, Kimimasa Ikeda, Kenji Sakai, Takashi Doi, Taichi Koyama, Minako Hoshi, Hirokazu Taniguchi, Masakazu Murakami, Eiji Kurokawa
An 85-year-old woman presented to her local physician in early August 2015 with a new-onset "swelling" of the anal region and was referred to our department for evaluation and treatment at the beginning of September. At our initial evaluation, the rectal examination showed a black mass lesion, approximately 3.0×1.5 cm in size, in the anal canal by November, the mass had grown to approximately 7.0×3.5 cm in size. The lesion was diagnosed as malignant melanoma by colonoscopic biopsy. Abdominal cystography computed tomography showed an area of lymphadenopathy around the rectum, but no distant metastasis was detected...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28121939/multiple-preinvasive-and-invasive-hpv-related-lesions-of-the-anogenital-tract-in-a-female-patient-with-hiv-infection-a-case-report
#16
Nicolò Clemente, Lara Alessandrini, Emanuela Vaccher, Antonino De Paoli, Monica Buttignol, Vincenzo Canzonieri, Francesco Sopracordevole
RATIONALE: Patients with human immunodeficiency virus (HIV) infection have been shown to be at increased risk for high-risk human papillomavirus (HR-HPV) infection of the anogenital tract. Furthermore, in the last decades, the introduction of highly active antiretroviral therapy (HAART) has increased the longevity of these patients who now live long enough to develop HPV-related cancers; hence, the impact of HPV infection on HIV-positive patients is of increasing concern. PATIENT CONCERNS: We reported the case of an HIV-positive female patient on HAART with a good virological and immunological response and with a long history of HPV-related intraepithelial and invasive lesions of the anogenital tract...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28099957/results-of-surgical-salvage-treatment-for-anal-canal-cancer-a-retrospective-analysis-with-overview-of-the-literature
#17
Benedetta Pesi, Stefano Scaringi, Carmela Di Martino, Giacomo Batignani, Francesco Giudici, Damiano Bisogni, Francesco Tonelli, Paolo Bechi
BACKGROUND AND AIM: Chemoradiotherapy (CRT) is the gold standard treatment for anal cancer, which permits the maintenance of the anal function. However, about 30-40% of patients develop local disease progression, for which surgery represents a good salvage therapy. The aim of this study is to evaluate survival and morbidity rate in patients who undergo salvage surgery in our single institution, with an overview of the literature. METHODS: A retrospective study was carried out on patients who underwent surgical treatment of anal canal cancer after failure of CRT...
January 19, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28092017/transanal-total-mesorectal-excision-for-a-large-leiomyosarcoma-at-the-lower-rectum-a-case-report-and-literature-review
#18
Nobuaki Hoshino, Koya Hida, Kenji Kawada, Takaki Sakurai, Yoshiharu Sakai
BACKGROUND: Rectal leiomyosarcoma (LMS) is an extremely rare disease. Previously, LMS was not properly distinguishable from gastrointestinal stromal tumor (GIST) until c-kit, a characteristic marker of GIST, was discovered in 1998. No standard therapeutic strategy for gastrointestinal LMS has been established except for surgical resection because of its rarity. Rectal LMS is often accompanied by symptoms, which can enable detection at a small size. However, when a large LMS is detected at the lower rectum, it is difficult to excise due to the narrow pelvic space...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28091845/comparison-of-the-clinical-results-of-abdominoperanal-intersphincteric-resection-and-abdominoperineal-resection-for-lower-rectal-cancer
#19
Shunsuke Tsukamoto, Yukihide Kanemitsu, Dai Shida, Hiroki Ochiai, Junichi Mazaki
BACKGROUND: The aim of this study was to compare the oncologic results of abdominoperanal intersphincteric resection (ISR) and abdominoperineal resection (APR). METHODS: Between 2003 and 2014, 277 consecutive patients with stage I-III low rectal cancer located within 5 cm from the anal verge underwent curative ISR and APR. A retrospective comparison of these two procedures was performed. RESULTS: Overall, 128 patients underwent ISR and 149 underwent APR...
January 16, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28035482/laparoscopic-prosthetic-parastomal-and-perineal-hernia-repair-after-abdominoperineal-resection
#20
G Dapri, L Gerard, L Cardinali, D Repullo, I Surdeanu, S H Sondji, G-B Cadière, S Saussez
No abstract text is available yet for this article.
January 2017: Techniques in Coloproctology
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