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mediastinal masses guidelines

David J McCracken, Melanie Bailey, Marie-Therese McDermott, Terence E McManus
Endobronchial ultrasound has become first line in the investigation of mediastinal lesions suspicious for malignancy in keeping with National Institute for Health and Care Excellence (NICE) guidelines; however, needle size and type required to maximise diagnostic sensitivity remains unclear. Previous meta-analyses have compared the use of ProCore with standard fine needle aspiration in the assessment of pancreatic masses with differences noted only in the number of passes required. We aim to assess whether a ProCore needle improves diagnostic sensitivity in EBUS-TBNA...
April 24, 2018: Irish Journal of Medical Science
Maximilian Kreibich, Matthias Siepe, Jochen Grohmann, Gregor Pache, Friedhelm Beyersdorf
OBJECTIVE: Azygos vein aneurysms (AVAs) are uncommon and infrequently diagnosed. When confronted with a patient presenting with an AVA, physicians can rely on only a few case reports after an extensive literature search. To date, no guideline, no rule, and no review on the optimal treatment strategy for these patients exist. METHODS: A PubMed and MEDLINE database search for papers and case reports describing AVA was performed. Cases from our own institutions were also reviewed...
July 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
Melissa A MacIver, J Brad Case, Eric L Monnet, Geraldine B Hunt, Philipp D Mayhew, Michelle L Oblak, Jeffrey J Runge, Ameet Singh, Daniel D Smeak, Michele A Steffey, Sarah E Boston
OBJECTIVE To characterize clinical findings, surgical procedures, complications, and outcomes in dogs undergoing extirpation of masses from the cranial mediastinum via video-assisted thoracic surgery (VATS) and establish preliminary guidelines for case selection when considering VATS for thymectomy in dogs. DESIGN Retrospective case series. ANIMALS 18 client-owned dogs that underwent extirpation of a cranial mediastinal mass by means of VATS at 5 academic referral hospitals from 2009 through 2014. PROCEDURES Medical records were reviewed and data extracted regarding signalment, clinical signs, physical examination findings, diagnostic imaging results, surgical approach and duration, cytologic and histologic examination results, complications, outcome, and cause of death, when applicable...
June 1, 2017: Journal of the American Veterinary Medical Association
A Schönning, J Karlén, T Frisk, M Heyman, J E Svahn, I Øra, L Kawan, B-M Holmqvist, C Björklund, A Harila-Saari, S Ranta
INTRODUCTION: Pediatric patients with Hodgkin lymphoma (HL) have several risk factors for venous thromboembolism (VTE). Although these patients are occasionally treated with thromboprophylaxis, no guidelines are implemented in Sweden. Scarce data from adult patients indicate an increased risk of VTE, but pediatric data is largely missing. Given the favorable overall survival of HL, there should reasonably be more focus on preventing complications. MATERIALS AND METHODS: We conducted a retrospective cohort study, including all patients registered in the Childhood Cancer Registry under the age of 18years diagnosed with HL between January 2005 and December 2015 in Sweden...
April 2017: Thrombosis Research
Uqba Khan, Tarik Hadid, Warda Ibrar, Dahlia Sano, Ayad Al-Katib
An 18-year-old African-American female presented with an episode of syncope. Initial investigations revealed large lung mass with invasion into right atrium along with lesions in kidneys and liver. Patient also developed superior vena cava syndrome due to lung mass. Biopsy of lung mass revealed diagnosis of composite lymphoma with involvement by primary mediastinal B-cell lymphoma (PMBCL) and classical Hodgkin lymphoma. Patient was started on dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin and rituximab (EPOCH-R) with complete response to treatment...
March 2017: Journal of Clinical Medicine Research
Katsuya Kato, Kenichi Gemba, Nobukazu Fujimoto, Keisuke Aoe, Yukio Takeshima, Kouki Inai, Takumi Kishimoto
PURPOSE: The purpose of this study was to clarify the characteristic findings of mesothelioma at the time of diagnosis, and determine precautions and guidelines for diagnosing mesothelioma early in imaging studies. MATERIALS AND METHODS: Overall, 327 patients with pleural mesothelioma were selected from 6030 patients who died of mesothelioma between 2003 and 2008 in Japan. Their imaging findings were examined retrospectively. RESULTS: Plaques were found in 35 % of computed tomography (CT) scans...
June 2016: Japanese Journal of Radiology
Momen M Wahidi, Felix Herth, Kazuhiro Yasufuku, Ray Wesley Shepherd, Lonny Yarmus, Mohit Chawla, Carla Lamb, Kenneth R Casey, Sheena Patel, Gerard A Silvestri, David J Feller-Kopman
BACKGROUND: Endobronchial ultrasound (EBUS) was introduced in the last decade, enabling real-time guidance of transbronchial needle aspiration (TBNA) of mediastinal and hilar structures and parabronchial lung masses. The many publications produced about EBUS-TBNA have led to a better understanding of the performance characteristics of this procedure. The goal of this document was to examine the current literature on the technical aspects of EBUS-TBNA as they relate to patient, technology, and proceduralist factors to provide evidence-based and expert guidance to clinicians...
March 2016: Chest
Yang Xia, Yun Ma, Sixto Arias, Hans Lee, Ko-Pen Wang
BACKGROUND: Transbronchial needle aspiration (TBNA), serving as a remarkably invaluable and minimally invasive technique, has been widely used for the diagnosis and staging of mediastinal adenopathy and masses. To date, the International Association for the Study of Lung Cancer (IASLC) and Wang's nodal map are two well-documented intrathoracic lymph node guidelines for the TBNA procedure. METHOD: We characterized IASLC's and Wang's map, and interpreted the correlation of the two maps station by station...
July 2015: Thoracic Cancer
S Constantinoiu, M Gheorghe, L Popa, C Ciocea, C Iosif, R Tiutiuca, A Iordache, I Cordoş
GIST are rare mesenchymal tumors of the digestive tract (less than 1% of the digestive tract neoplasia). Of these, less than 1% are found in the esophagus. Surgery is the main treatment of GIST and is supported by targeted therapy with tyrosine kinase inhibitors like imatinibmesylate. We present the case of a female patient of 51 years, admitted in our clinic for a bulky tumor in the posterior mediastinum, diagnosed after investigations performed for fatigue for the great efforts. Clinical examination was unspecific...
May 2015: Chirurgia
Abdul Hannan, Noreen Akhter, Ather Saeed Kazmi, Narjis Muzaffar
Secondary transformation in Germ Cell Tumours (GCT) is an extremely rare event. We report here a case of malignant melanoma arising in primary mediastinal GCT. A young male presented with new onset dyspnoea and a mediastinal mass. As serum alpha fetoprotein was raised, a diagnosis of primary mediastinal GCT was made. He achieved remission with standard chemotherapy and resection of the mass. After a year, he relapsed with widespread disease which on work-up revealed malignant melanoma. As examination for cutaneous melanoma was unremarkable, a diagnosis of mediastinal GCT with secondary transformation to melanoma was made...
January 2015: JPMA. the Journal of the Pakistan Medical Association
Maja V Maraldo, Bouthaina S Dabaja, Andrea R Filippi, Tim Illidge, Richard Tsang, Umberto Ricardi, Peter M Petersen, Deborah A Schut, John Garcia, Jayne Headley, Amy Parent, Benoit Guibord, Riccardo Ragona, Lena Specht
PURPOSE: Early-stage Hodgkin lymphoma (HL) is a rare disease, and the location of lymphoma varies considerably between patients. Here, we evaluate the variability of radiation therapy (RT) plans among 5 International Lymphoma Radiation Oncology Group (ILROG) centers with regard to beam arrangements, planning parameters, and estimated doses to the critical organs at risk (OARs). METHODS: Ten patients with stage I-II classic HL with masses of different sizes and locations were selected...
May 1, 2015: International Journal of Radiation Oncology, Biology, Physics
Nagendra Madisi, Kenneth Miller
SESSION TITLE: Cancer Student/Resident Case Report Posters IIISESSION TYPE: Medical Student/Resident Case ReportPRESENTED ON: Tuesday, October 28, 2014 at 01:30 PM - 02:30 PMINTRODUCTION: Primary pulmonary leiomyosarcomas (PPPLS) are exceptionally rare tumors and constitute only 0.2-0.5% of the total lung cancers. Sarcomas metastasizing to brain or heart are rare and PPPLS, with metastases to both have never been reported to our knowledge . Here, we present a case of high-grade PPPLS with brain and cardiac metastases...
October 1, 2014: Chest
Jeffrey I Zwicker, Kenneth A Bauer
A previously healthy 41-year-old man presents with left leg pain and shortness of breath. He has a 20–packyear history of smoking but quit 2 years ago. An ultrasound of the left leg shows thrombosis of the superficial femoral and popliteal veins.Onchest computed tomography (CT) angiogram, there is a large right hilar mass and enlarged mediastinal lymph nodes but no pulmonary emboli. He is treated with therapeutic doses of low–molecular weight heparin (LMWH), with brief interruptions for invasive procedures and surgery...
November 10, 2014: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Mohamad Alkhouli, Paul Sandhu, Susan E Wiegers, Pravin Patil, John Panidis, Amit Pursnani
BACKGROUND: Incidental extracardiac findings (ECFs) have been described and studied in myocardial perfusion imaging, cardiac computed tomography, and cardiac magnetic resonance scanning. The literature is surprisingly limited with regard to ECFs in echocardiography. The aim of this study was to evaluate the prevalence and the clinical significance of ECFs in routine echocardiographic studies. METHODS: The literature in other cardiovascular modalities was searched to identify and classify ECFs...
May 2014: Journal of the American Society of Echocardiography
Alberto Marchevsky, Alex Marx, Philipp Strobel, Saul Suster, Federico Venuta, Mirella Marino, Samuel Yousem, Maureen Zakowski
No abstract text is available yet for this article.
February 2014: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Diana Cimpoesu, Lucian Stoica, Anda Paulet, Antoniu Petris
SESSION TYPE: Critical Care Global Case Report PostersPRESENTED ON: Tuesday, October 23, 2012 at 01:30 PM - 02:30 PMINTRODUCTION: The incidence of cardiac involvement among patients with hydatid disease is 0.5-3%, and a pericardial site of implantation is even less common [3]. Severe complications impose a prompt diagnosis and treatment in ED. The management is very critical and time-dependent if the patient develops an anaphylactic shock with cardiopulmonary arrest risk. We present a rare case of multiple pericardial hydatid cysts that resulted in anaphylactic shock...
October 1, 2012: Chest
Guglielmo Paradies, Francesca Zullino, Antonio Orofino, Samuele Leggio
BACKGROUND: In the pediatric age, mediastinal teratomas are an infrequent observation, accounting for only 7%-11% of extragonadal teratomas. Mainly located in the anterior mediastinum arising from the thymic gland, or exceptionally, from ectopic thyroid tissue, they may rarely be observed in the posterior mediastinum, sometimes in a paravertebral position, simulating a neuroblastoma. The Authors have extrapolated, from their entire experience of teratomas, 3 cases, mostly operated as emergencies; 1 of them was treated just after birth...
July 2013: Annali Italiani di Chirurgia
Charles S Bryan, William M Yarbrough
The consequences of deep wound infections before, during, and after coronary artery bypass grafting have prompted research to clarify risk factors and explore preventive measures to keep infection rates at an irreducible minimum. An analysis of 42 studies in which investigators used multivariate logistic regression analysis revealed that diabetes mellitus and obesity are by far the chief preoperative risk factors. A 4-point preoperative scoring system based on a patient's body mass index and the presence or absence of diabetes is one practical way to determine the risk of mediastinitis, and other risk-estimate methods are being refined...
2013: Texas Heart Institute Journal
David S Ettinger, Gregory J Riely, Wallace Akerley, Hossein Borghaei, Andrew C Chang, Richard T Cheney, Lucian R Chirieac, Thomas A D'Amico, Todd L Demmy, Ramaswamy Govindan, Frederic W Grannis, Stefan C Grant, Leora Horn, Thierry M Jahan, Ritsuko Komaki, Feng-Ming Spring Kong, Mark G Kris, Lee M Krug, Rudy P Lackner, Inga T Lennes, Billy W Loo, Renato Martins, Gregory A Otterson, Jyoti D Patel, Mary C Pinder-Schenck, Katherine M Pisters, Karen Reckamp, Eric Rohren, Theresa A Shapiro, Scott J Swanson, Kurt Tauer, Douglas E Wood, Stephen C Yang, Kristina Gregory, Miranda Hughes
Masses in the anterior mediastinum can be neoplasms (eg, thymomas, thymic carcinomas, or lung metastases) or non-neoplastic conditions (eg, intrathoracic goiter). Thymomas are the most common primary tumor in the anterior mediastinum, although they are rare. Thymic carcinomas are very rare. Thymomas and thymic carcinomas originate in the thymus. Although thymomas can spread locally, they are much less invasive than thymic carcinomas. Patients with thymomas have 5-year survival rates of approximately 78%. However, 5-year survival rates for thymic carcinomas are only approximately 40%...
May 1, 2013: Journal of the National Comprehensive Cancer Network: JNCCN
J Kriz, R-P Mueller, H Mueller, G Kuhnert, A Engert, C Kobe, U Haverkamp, H T Eich
PURPOSE: The risk factor "large mediastinal tumor mass" is an internationally accepted unfavorable prognostic factor in the staging of Hodgkin's lymphoma (HL). The definition of this risk factor varies considerably between large cooperative study groups. The purpose of the present analysis was to determine to which degree data obtained from chest radiograph (CRX) give the same results as those from CT scans (CT). METHODS: A total of 145 de novo HL patients in early unfavorable and advanced stages were included in this study...
November 2012: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
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