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infection prophylaxy surgery

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https://www.readbyqxmd.com/read/28531930/in-reply-to-optimal-strategy-to-control-surgical-site-infection-following-deep-brain-stimulation-surgery-adequate-management-of-risk-factors-topical-application-of-vancomycin-powder-in-the-surgical-wound-and-preoperative-antibiotic-prophylaxis
#1
https://www.readbyqxmd.com/read/28531929/optimal-strategy-to-control-surgical-site-infection-following-deep-brain-stimulation-surgery-adequate-management-of-risk-factors-topical-application-of-vancomycin-powder-in-the-surgical-wound-and-preoperative-antibiotic-prophylaxis
#2
https://www.readbyqxmd.com/read/28529866/which-orthopaedic-patients-are-infected-with-gram-negative-non-fermenting-rods
#3
Omid Jamei, Shpresa Gjoni, Besa Zenelaj, Benjamin Kressmann, Wilson Belaieff, Didier Hannouche, Ilker Uçkay
Background : 1(st) and 2(nd) generation cephalosporins used for perioperative prophylaxis in orthopaedic surgery do not cover non-fermenting Gram-negative rods (NFR). Methods: Epidemiological cohort study of adult patients operated for orthopedic infections between 2004 and 2014 with perioperative cefuroxim or vancomycin prophylaxis. Exclusion of polyneuropathic ischemic foot infections and septic bursitis cases. Results: Of the total 1840 surgical procedures in the study, 430 grew Gram-negative pathogens (23%), of which 194 (11%) were due to NFR and 143 (8%) to Pseudomonas aeruginosa...
2017: J Bone Jt Infect
https://www.readbyqxmd.com/read/28529861/local-intra-wound-administration-of-powdered-antibiotics-in-orthopaedic-surgery
#4
REVIEW
Andrew N Fleischman, Matthew S Austin
Surgical site infection (SSI) is one of the most common complications after orthopaedic surgery, leading to significant morbidity and its associated costs. Surgical guidelines strongly recommend the use of systemic antibiotic prophylaxis to reduce the risk for developing SSI. Locally administered powdered antibiotics have the potential to provide remarkably high intra-wound concentrations without risk for systemic toxicity. However, a paucity of high quality evidence in the orthopaedic literature has prevented widespread adoption of this technique...
2017: J Bone Jt Infect
https://www.readbyqxmd.com/read/28527564/prospective-comparison-of-perioperative-antibiotic-management-protocols-in-oncological-head-and-neck-surgery
#5
Alexander K Bartella, Mohammad Kamal, Jan Teichmann, Anita Kloss-Brandstätter, Timm Steiner, Frank Hölzle, Bernd Lethaus
OBJECTIVES: The adequate perioperative antibiotic prophylaxis in head and neck cancer surgery is an important and easy applicable tool to decrease nosocomial morbidity and mortality by reducing the rate of infections. In the study a strictly perioperative antibiosis is compared with an extended postoperative prophylactic antibiosis. We aim to clarify the value of postoperative prophylactic antibiosis for the recovery and clinical course of patients. MATERIAL AND METHODS: In this prospective study 75 consecutive patients, who underwent major oncological head and neck surgery were included and divided in three groups, each containing 25 patients...
April 20, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28497247/-medial-closed-wedge-osteotomy-of-the-distal-femur-in-biplanar-technique-and-a-specific-plate-fixator
#6
REVIEW
P Lobenhoffer, K Kley, D Freiling, R van Heerwaarden
OBJECTIVE: Correction of distal femur deformity by closed-wedge biplanar osteotomy. INDICATIONS: Metaphyseal frontal plane deformities of the femur. CONTRAINDICATIONS: Osteoarthritis of the contralateral compartment, total loss of the contralateral meniscus, acute/chronic infection, limited range-of-motion, poor soft-tissue conditions at site of surgery. SURGICAL TECHNIQUE: Skin incision at metaphyseal area of femur...
May 11, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28486386/fluid-overload-and-cumulative-thoracostomy-output-are-associated-with-surgical-site-infection-after-pediatric-cardiothoracic-surgery
#7
Anthony A Sochet, Aoibhinn Nyhan, Michael C Spaeder, Alexander M Cartron, Xiaoyan Song, Darren Klugman, Anna T Brown
OBJECTIVES: To determine the impact of cumulative, postoperative thoracostomy output, amount of bolus IV fluids and peak fluid overload on the incidence and odds of developing a deep surgical site infection following pediatric cardiothoracic surgery. DESIGN: A single-center, nested, retrospective, matched case-control study. SETTING: A 26-bed cardiac ICU in a 303-bed tertiary care pediatric hospital. PATIENTS: Cases with deep surgical site infection following cardiothoracic surgery were identified retrospectively from January 2010 through December 2013 and individually matched to controls at a ratio of 1:2 by age, gender, Risk Adjustment for Congenital Heart Surgery score, Society of Thoracic Surgeons-European Association for Cardiothoracic Surgery category, primary cardiac diagnosis, and procedure...
May 8, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28484678/reduced-surgical-site-infection-rates-following-spine-surgery-using-an-enhanced-prophylaxis-protocol
#8
Alexa M Dessy, Frank J Yuk, Akbar Y Maniya, James G Connolly, John T Nathanson, Jonathan J Rasouli, Tanvir F Choudhri
BACKGROUND: Postoperative surgical site infection (SSI) is a common complication after spine surgery. Reduction of SSI has many benefits including, but not limited to, the reduced length of stay, readmission rates, and morbidity and mortality. OBJECTIVE: To determine whether an enhanced antibiotic prophylaxis reduced the rate of surgical site infections in spine surgery. METHODS: This is a retrospective observation study which analyzed the incidence of postoperative SSI following a consecutive series of 1,486 cervical, thoracic and lumbar spine operations performed at a single institution by the senior author between the dates of October 2001 to March 2014...
April 6, 2017: Curēus
https://www.readbyqxmd.com/read/28483725/opportunities-for-system-level-improvement-across-antibiotic-use-in-the-surgical-pathway
#9
E Charani, R Ahmad, C Tarrant, G Birgand, A Leather, M Mendelson, S R Moonesinghe, N Sevdalis, S Singh, A Holmes
Optimizing antibiotic prescribing across the surgical pathway (before, during, and after surgery) is a key aspect of tackling important drivers of antimicrobial resistance and simultaneously decreasing the burden of infection at the global level. In the UK alone, 10 million patients undergo surgery every year, which is equivalent to 60% of the annual hospital admissions having a surgical intervention. The overwhelming majority of surgical procedures require effectively limited delivery of antibiotic prophylaxis to prevent infections...
May 5, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28475790/prevalence-of-healthcare-associated-infections-and-antimicrobial-use-among-adult-inpatients-in-singapore-acute-care-hospitals-results-from-the-first-national-point-prevalence-survey
#10
Yiying Cai, Indumathi Venkatachalam, Nancy W Tee, Thean Yen Tan, Asok Kurup, Sin Yew Wong, Chian Yong Low, Yang Wang, Winnie Lee, Yi Xin Liew, Brenda Ang, David C Lye, Angela Chow, Moi Lin Ling, Helen M Oh, Cassandra A Cuvin, Say Tat Ooi, Surinder K Pada, Chong Hee Lim, Jack Wei Chieh Tan, Kean Lee Chew, Van Hai Nguyen, Dale A Fisher, Herman Goossens, Andrea L Kwa, Paul A Tambyah, Li Yang Hsu, Kalisvar Marimuthu
Background: We conducted a national point prevalence survey (PPS) to determine the prevalence of healthcare-associated infections (HAIs) and antimicrobial use (AMU) in Singapore acute-care hospitals. Methods: Trained personnel collected HAI, AMU, and baseline hospital- and patient-level data of adult inpatients from 13 private and public acute-care hospitals between July 2015 and February 2016, using the PPS methodology developed by the European Centre for Disease Prevention and Control...
May 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28473167/review-of-mrsa-screening-and-antibiotics-prophylaxis-in-orthopaedic-trauma-patients-the-risk-of-surgical-site-infection-with-inadequate-antibiotic-prophylaxis-in-patients-colonized-with-mrsa
#11
H J Iqbal, N Ponniah, S Long, N Rath, M Kent
AIMS: The primary aim of this study was to determine whether orthopaedic trauma patients receive appropriate antibiotic prophylaxis keeping in view the results of their MRSA screening. The secondary aim was to analyse the risk of developing MRSA surgical site infection with and without appropriate antibiotic prophylaxis in those colonized with MRSA. PATIENTS AND METHODS: We reviewed 400 consecutive orthopaedic trauma patient episodes. Preoperative MRSA screening results, operative procedures, prophylactic antibiotics and postoperative course were explored...
April 13, 2017: Injury
https://www.readbyqxmd.com/read/28470334/transrectal-ultrasound-guided-prostate-biopsy-in-the-era-of-increasing-fluoroquinolone-resistance-prophylaxis-with-single-dose-ertapenem
#12
Michael Seitz, Christian Stief, Raphaela Waidelich, Markus Bader, Derya Tilki
PURPOSE: The aim of the study was to compare single-dose ertapenem (ERT) with the 3-day regime of ciprofloxacin (CIP) for prophylaxis of possible infections following transrectal prostate biopsy. METHODS: Data from a consecutive group of 542 patients from January 2012 to January 2017 were retrospectively analysed. As preinterventional prophylaxis patient group A (179) received 500 mg CIP twice a day for three days, beginning on the day before the biopsy (until June 2013); group B (363) received a single dose of ERT 60 min prior to intervention...
May 3, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28467526/centers-for-disease-control-and-prevention-guideline-for-the-prevention-of-surgical-site-infection-2017
#13
Sandra I Berríos-Torres, Craig A Umscheid, Dale W Bratzler, Brian Leas, Erin C Stone, Rachel R Kelz, Caroline E Reinke, Sherry Morgan, Joseph S Solomkin, John E Mazuski, E Patchen Dellinger, Kamal M F Itani, Elie F Berbari, John Segreti, Javad Parvizi, Joan Blanchard, George Allen, Jan A J W Kluytmans, Rodney Donlan, William P Schecter
Importance: The human and financial costs of treating surgical site infections (SSIs) are increasing. The number of surgical procedures performed in the United States continues to rise, and surgical patients are initially seen with increasingly complex comorbidities. It is estimated that approximately half of SSIs are deemed preventable using evidence-based strategies. Objective: To provide new and updated evidence-based recommendations for the prevention of SSI...
May 3, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28463223/-recommendations-for-prevention-of-surgical-site-infection-in-adult-elective-arthroplasty
#14
Juan Carlos Chuluyán, Andrea Vila, Ana Laura Chattás, Marcelo Montero, Claudia Pensotti, Claudia Tosello, Marisa Sánchez, Cecilia Vera Ocampo, Guillermina Kremer, Rodolfo Quirós, Guillermo A Benchetrit, Carolina Fernanda Pérez, Ana Laura Terusi, Francisco Nacinovich
Surgical site infections complicating orthopedic implant surgeries prolong hospital stay and increase risk of readmission, hospitalization costs and mortality. These recommendations are aimed at: (i) optimizing compliance and incorporating habits in all surgery phases by detecting risk factors for surgical site infections which are potentially correctable or modifiable; and (ii) optimizing preoperative antibiotic prophylaxis as well as intraoperative and postoperative care.
2017: Medicina
https://www.readbyqxmd.com/read/28462662/antibiotic-prophylaxis-for-clean-neck-surgery
#15
K Vamvakidis, K Rellos, M Tsourma, C Christoforides, E Anastasiou, K A Zorbas, A Arambatzi, M E Falagas
The frequency of surgical site infections (SSIs) after clean neck surgery is low and antibiotic prophylaxis is not recommended. This retrospective study investigated the effect of perioperative prophylactic antimicrobial therapy on the development of infections. A total of 807 consecutive patients undergoing clean neck surgery were included in the study. Antimicrobial prophylaxis with intravenous cefuroxime was administered in 518 cases. Although patients who received prophylaxis had a lower rate of SSIs than those who did not receive antibiotics, this was not statistically significant (0...
May 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28462657/second-generation-cephalosporin-antibiotic-prophylaxis-and-clostridium-difficile-infection-in-hip-and-knee-arthroplasty
#16
K Al-Tawil, A Babu, M Loeffler, T Williams
Introduction The use of broad spectrum cephalosporin antibiotics has been discouraged by the Department of Health in England because of the link to increased Clostridium difficile infection rates. The aim of this study was to evaluate whether a local protocol that included the use of second generation cephalosporin (cefuroxime) antibiotics as a prophylactic agent was associated with increased risk of C difficile in elective hip and knee arthroplasty patients. Methods A retrospective intention-to-treat study was conducted...
May 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28461999/mulitcenter-study-on-antibiotic-prophylaxis-infectious-complications-and-risk-assessment-in-tur-p
#17
Laila Schneidewind, Jennifer Kranz, Daniel Schlager, Dimitri Barski, Sandra Mühlsteadt, Markus Grabbert, Fabian Queissert, Tanja Frank, Alexandre Egon Pelzer
INTRODUCTION: Transurethral resection of the prostate is one of the most frequent urological procedures. Urinary tract infections represent major sequelae, but data about antibiotic prophylaxis in TUR-P are controversial and outdated. MATERIAL AND METHODS: We conducted a retrospective multicentre study of TUR-P in ten German hospitals. Primary endpoints were epidemiological and outcome data of TUR-P. Secondary endpoints were the identification of factors associated with febrile UTIs and sepsis after TUR-P...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28461965/total-knee-arthroplasty-and-infection-how-surgeons-can-reduce-the-risks
#18
REVIEW
Nicola Ratto, Chiara Arrigoni, Federica Rosso, Matteo Bruzzone, Federico Dettoni, Davide Edoardo Bonasia, Roberto Rossi
Total joint arthroplasty (TJA) is one of the most common orthopaedic procedures. Nevertheless, several complications can lead to implant failure.Peri-prosthetic joint infections (PJI) certainly represent a significant challenge in TJA, constituting a major cause of prosthetic revision. The surgeon may have an important role in reducing the PJI rate by limiting the impact of significant risk factors associated to either the patient, the operative environment or the post-operative care.In the pre-operative period, several preventive measures may be adopted to manage reversible medical comorbidities...
September 2016: EFORT Open Rev
https://www.readbyqxmd.com/read/28461390/propofol-sedation-exacerbates-kidney-pathology-and-dissemination-of-bacteria-during-staphylococcus-aureus-bloodstream-infections
#19
Lavanya Visvabharathy, Nancy E Freitag
Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for large numbers of post-surgical nosocomial infections across the United States and worldwide. Propofol anesthesia is widely used in surgery and in intensive care units, and recent evidence indicates that even brief exposure to propofol can substantially increase host susceptibility to microbial infection. Here we delineate the impact of propofol sedation on MRSA blood stream infections in mice in the presence and absence of prophylactic antibiotic treatment...
May 1, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28458711/urinary-tract-infections-in-kidney-transplant-recipients-1-st-year-after-transplantation
#20
Seyyede Fatemeh Shams, Elham Shaarbaf Eidgahi, Zahra Lotfi, Azad Khaledi, Sepideh Shakeri, Maryam Sheikhi, Afsane Bahrami
BACKGROUND: One of the main causes of adverse complications following kidney transplantation is urinary tract infection (UTI). This study was done to define the incidence rate, clinical profiles, causative microorganisms, and UTI risk factors among kidney transplant recipients in Mashhad city. MATERIALS AND METHODS: In this retrospective study, we perused medical files of 247 kidney recipients who underwent transplant surgery at Mashhad University Montaserie Hospital, during 2012-2014...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
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