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infection prophylaxy surgery

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https://www.readbyqxmd.com/read/29240639/absorbable-antibiotic-beads-prophylaxis-in-immediate-breast-reconstruction
#1
Denise M Kenna, Busayo Irojah, Kimber Lee Mudge, Kendra Eveler
BACKGROUND: Breast reconstruction with tissue expander is the most common mode of reconstruction following mastectomy. Infection necessitating tissue expander removal is a significant complication leading to patient distress as well as increased health care costs. METHODS: Over 3 years, 127 breast reconstructions with tissue expanders were performed by a single surgeon. Fifty-nine of these reconstructions were performed using a standardized protocol in which patients washed with chlorhexidine several days prior to surgery and received intravenous antibiotics preoperatively...
December 13, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29240638/antibiotic-prophylaxis-after-immediate-breast-reconstruction-the-reality-of-its-efficacy
#2
Kavitha Ranganathan, Erika D Sears, Lin Zhong, Ting-Ting Chung, Kevin C Chung, Jeffrey H Kozlow, Adeyiza O Momoh, Jennifer F Waljee
PURPOSE: Numerous techniques are used to prevent infection after immediate implant-based breast reconstruction. Postoperative antibiotic prophylaxis (PAP) is commonly prescribed to decrease the risk of reconstructive failure, despite conflicting evidence regarding its effectiveness. We sought to determine whether PAP decreases the risk of infection-related explantation in the setting of immediate prosthesis-based breast reconstruction. METHODS: Using Truven MarketScan databases, we identified all patients who underwent immediate implant reconstruction between 1/2010-6/2014 with at least 6 months of follow-up...
December 13, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29238110/intrawound-vancomycin-powder-as-the-prophylaxis-of-surgical-site-infection-after-invasive-spine-surgery-with-a-high-risk-of-infection
#3
Tetsuro Hida, Kei Ando, Kazuyoshi Kobayashi, Kenyu Ito, Mikito Tsushima, Akiyuki Matsumoto, Masayoshi Morozumi, Satoshi Tanaka, Masaaki Machino, Kyotaro Ota, Shunsuke Kanbara, Sadayuki Ito, Yoshihiro Nishida, Naoki Ishiguro, Shiro Imagama
Surgical site infections (SSIs) are one of the most serious complications in spine surgery. We investigated the efficacy of locally administered vancomycin (VCM) powder for prophylaxis on SSI after invasive spine surgery. We retrospectively studied 174 consecutive patients who underwent spine surgery. In patients of the VCM group (n = 81), VCM powder was administered in the wound before closing wound. Patients who did not receive VCM treatment were set as a control group (n = 93). We compared the patients' background, operation time, intraoperative blood loss, usage of implants, presence of deep SSI, and side effects between the two groups...
November 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/29234644/prophylaxis-with-nasal-decolonization-in-patients-submitted-to-total-knee-and-hip-arthroplasty-systematic-review-and-meta-analysis
#4
REVIEW
David Sadigursky, Henrique Santos Pires, Saulo Américo Caldas Rios, Francisco Luiz Borja Rodrigues Filho, Gustavo Castro de Queiroz, Mateus Lemos Azi
Despite the evolution of the total knee and hip arthroplasty surgery, high postoperative complication rates in the short and long term still persist. Infection is one of the most challenging complications; due to its gravity and treatment difficulties, prophylaxis protocols have been created to decrease its incidence. The objective of this study was to evaluate the impact of the prophylaxis protocol for methicillin-resistant Staphylococcus aureus decolonization of the nares in patients previously identified by swab cultures, who were to be submitted to a total joint arthroplasty...
November 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29226971/intravenous-dexamethasone-for-prophylaxis-of-postoperative-nausea-and-vomiting-after-administration-of-long-acting-neuraxial-opioids-a-systematic-review-and-meta-analysis
#5
REVIEW
S Grape, I Usmanova, K R Kirkham, E Albrecht
Long-acting neuraxial opioids provide excellent analgesia after surgery, but are associated with higher rates of postoperative nausea and vomiting. Dexamethasone effectively prevents postoperative nausea and vomiting after general anaesthesia, but its value in patients receiving long-acting neuraxial opioids is undetermined. Therefore, the objective of this meta-analysis was to assess the prophylactic anti-emetic efficacy of intravenous (i.v.) dexamethasone in this population. The study methodology followed the PRISMA statement guidelines...
December 11, 2017: Anaesthesia
https://www.readbyqxmd.com/read/29224055/peri-operative-antibiotic-treatment-of-bacteriuria-reduces-early-deep-surgical-site-infections-in-geriatric-patients-with-proximal-femur-fracture
#6
Ronny Langenhan, Stefanie Bushuven, Niklas Reimers, Axel Probst
PURPOSE: The aim of this study was to conduct a re-evaluation of current strategies for peri-operative prophylaxis of infections in orthopaedic surgery of geriatric patients (≥65 years) with proximal femoral fractures (PFF). METHODS: Between 01/2010 and 08/2014 all post-operative infections after stabilization of PFF of 1,089 geriatric patients were recorded retrospectively. All patients pre-operatively received a single dose of 1.5 g cefuroxime (group 1). These were compared to prospectively determined post-operative rates of surgical site infection (SSI) of 441 geriatric patients, which were operated on between 09/2014 and 03/2017 due to PFF...
December 9, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29221299/surgical-site-infections-after-lung-resection-a-prospective-study-of-risk-factors-in-1-091-consecutive-patients
#7
Andrea Imperatori, Elisa Nardecchia, Lorenzo Dominioni, Daniele Sambucci, Sebastiano Spampatti, Giancarlo Feliciotti, Nicola Rotolo
Background: To assess incidence and risk factors of surgical site infections (SSI) (wound infection, pneumonia, empyema) in a monocentric series of patients undergoing lung resection over a decade. Methods: All patients undergoing lung resection at our institution in 2006-2015 [wedge resection, n=579; lobectomy, n=472 (12% after chemo/radiotherapy); pneumonectomy, n=40 (47% after chemo/radiotherapy)], were prospectively enrolled. Perioperative SSI risk factors were recorded: age, gender, blood haemoglobin, lymphocyte count, serum albumin, forced expiratory volume in 1 second percentage (FEV1%) of predicted, antibiotic prophylaxis, length of stay, diabetes, malignancy, steroid therapy, induction chemo/radiotherapy, resection in 2006-2010/2011-2015, urgent/elective procedure, videothoracoscopic/open approach, resection type, operative time...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29208819/antibiotic-prophylaxis-in-cataract-surgery-an-evidence-based-approach
#8
REVIEW
Aravind Haripriya
Various protocols are being followed for endophthalmitis prophylaxis in cataract surgery, and this subject continues to be a matter of debate. We summarize the most recent evidence-based studies on this topic with additional stress on intracameral (IC) antibiotic prophylaxis. Here, we discuss several large, international clinical studies which discuss the efficacy, adoption, safety, cost, and newer trends in antibiotic prophylaxis. Majority of these studies report a significant reduction in endophthalmitis rates with IC antibiotic prophylaxis...
December 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29205141/deep-spinal-infection-in-instrumented-spinal-surgery-diagnostic-factors-and-therapy
#9
M Dobran, A Marini, M Gladi, D Nasi, R Colasanti, R Benigni, Francesca Mancini, M Iacoangeli, M Scerrati
AIM: Postoperative surgical site infections (SSI) are complication of spinal surgery. These complications may lead to a poor outcome with neurological deficits, spinal deformity and chronic pain. The purpose of this study is to explore the statistical value of diagnostic parameters and the proper therapy. METHOD: We retrospectively reviewed 550 patients who underwent spinal instrumentation at our department from January 2011 to December 2015. The SSI was present in 16 patients out of 550 operated...
May 2017: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/29203089/multivariate-analysis-of-risk-factors-for-postoperative-wound-infection-following-oral-and-oropharyngeal-cancer-surgery
#10
Margita Belusic-Gobic, Arijan Zubovic, Robert Cerovic, Andrea Dekanic, Diana Marzic, Gordana Zamolo
PURPOSE: The goal of this study was to identify risk factors for wound infections in patients with oral cancer who underwent surgical procedures. MATERIALS AND METHODS: This study included 195 patients who underwent surgical treatment of oral and oropharyngeal cancer over a 7-year period. Wound infection was defined as the occurrence of purulent content from the wound or as an appearance of exudate with signs of local infection and positive cultures taken from the wound...
November 10, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29189125/use-of-antibiotic-loaded-biomaterials-for-the-management-of-bone-prosthesis-infections-rationale-and-limits
#11
Matilde Tschon, Maria Sartori, Deyanira Contartese, Gianluca Giavaresi, Nicolo Nicoli Aldini, Milena Fini
BACKGROUND: Periprosthetic joint infection still represents a challenging issue for the orthopedic community. In the United States approximately a million joint arthroplasties are performed each year, with infection rates ranging from 1 to 2%: revisions has significant implications in health care costs and appropriate resources management. The use of locally applied antibiotics as a prophylaxis measure or as a component of the therapeutic approach in primary or revision surgery is finalized at eliminating any microorganism and strengthening the effectiveness of systemic therapy...
November 29, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29188677/scanning-electron-3d-confocal-and-stereotactic-microscopies-morpho-structural-analysis-of-antibiotic-loaded-cement-porosity-in-three-different-formulations
#12
D Fenga, G Vermiglio, F Traina, A Favaloro, M A Rosa
Chronic osteoarticular infections such as osteomyelitis or periprosthetic joint infection (PJI) have become a growing problem over the years. The “gold standard” in local antibiotic administration is still the antibiotic-loaded acrylic bone cement (ALABC) which is used in both prophylaxis, because it has been shown it can reduce the risk of infection and used in therapy during a “two-stage surgery” in PJI or in chronic osteomyelitis. We performed morphological analysis of three different formulations of antibiotic-loaded cement (ALABC) using techniques of light microscopy, scanning electron microscopy (SEM) and 3D immunofluorescence, in order to explain how the morphological aspects of cement could influence and modulate antibiotic elution...
October 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29188383/-postoperative-care-and-options-for-scar-treatment-in-eyelid-surgery
#13
REVIEW
M Keserü, S Dulz, A Wolf, S Green, U Press, U Schaudig
Oculoplastic surgery places special demands on postoperative care because of the functional importance of the eyelids for the ocular surface. We present an overview of postoperative care after surgical eyelid interventions. All options, limits and the scientific evidence are discussed with a special focus on the treatment of postoperative edema, analgesia, infection prophylaxis and scar treatment.
November 29, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29180191/suture-thread-check-test-for-detection-of-surgical-site-contamination-a-prospective-study
#14
Francesco Iovino, Pasquale Pio Auriemma, Luca Dani, Giovanna Donnarumma, Alfonso Barbarisi, Vincenza Mallardo, Federica Calò, Nicola Coppola
BACKGROUND: Surgical site infection (SSI) is a common complication of surgical procedures. AIM: Our study aimed at investigating a new method based on assessment of suture thread colonization to identify patients developing an SSI. MATERIALS AND METHODS: We prospectively enrolled 119 patients undergoing elective surgery. For each patient, a synthetic absorbable thread in Lactomer 9-1 (Polisorb Gauge 2) inserted in the surgical site at the end of surgery was sent to the microbiology laboratory after 48 h to assess colonization of its inner tract...
December 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/29179565/american-urological-association-antibiotic-best-practice-statement-and-ureteroscopy-does-antibiotic-stewardship-help
#15
Daniel Greene, Bradley C Gill, Bryan Hinck, Yaw A Nyame, Nima Almassi, Krishnamurthi Venkatesh, Mark Noble, Sri Sivalingam, Manoj Monga
PURPOSE: To determine compliance with American Urological Association (AUA) antimicrobial prophylaxis best practice statement and whether the use of postoperative antibiotics is associated with lower rates of postoperative urinary tract infection (UTI) in patients with nephroureterolithiasis and a negative preoperative urine culture undergoing ureteroscopy. MATERIALS AND METHODS: A retrospective review of all adult patients undergoing ureteroscopy from 2013-2014 for stone disease with a negative preoperative urine was conducted...
November 27, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29178309/antibiotic-loaded-bone-cement-as-prophylaxis-in-total-joint-replacement
#16
REVIEW
Javier Martínez-Moreno, Virginia Merino, Amparo Nácher, José Luis Rodrigo, Mónica Climente, Matilde Merino-Sanjuán
One of its most serious complications associated with arthroplasty is the development of infections. Although its prevalence is only between 0.5% and 3%, in some cases it can lead to death. Therefore, an important challenge in joint surgery is the prevention of infections when an arthroplasty is performed. The use of antibiotic-loaded cements could be a suitable tool due to numerous advantages. The main advantage of the use of antibiotic loading into bone cement derives directly from antibiotic release in the effect site, allowing achievement of high concentrations at the site of action, and minimal or no systemic toxicity...
November 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29167293/perioperative-antibiotic-prophylaxis-has-no-effect-on-time-to-positivity-and-proportion-of-positive-samples-a-cohort-study-of-64-cutibacterium-acnes-bone-and-joint-infections
#17
Alexia Anagnostopoulos, Daniel A Bossard, Bruno Ledergerber, Patrick O Zingg, Annelies S Zinkernagel, Christian Gerber, Yvonne Achermann
If a bone or joint infection is suspected, perioperative antibiotic prophylaxis is frequently withheld until the intraoperative microbiological sampling has been performed. This practice builds upon the hypothesis that perioperative antibiotics could render culture results negative and thus impede tailored antibiotic treatment of infections. We aimed to assess the influence of antibiotic prophylaxis within 30 to 60 minutes before surgery on time to positivity of microbiological samples and proportion of positive samples in Cutibacterium acnes bone and joint infections...
November 22, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29158030/the-role-of-ayurveda-management-in-preventing-surgical-site-infections-instead-of-surgical-antibiotic-prophylaxis
#18
Subhash Yadav, Sanjay Jain, Jatinder Chaudhary, Rahul Bansal, Manoj Sharma
It is probably for the first time in the history of modern surgery that Benign Prostate Hyperplasia (BPH) surgery which belongs to 'clean contaminated' class and requires at least 3 doses of prophylactic antibiotic as per recommendations by American Urology Association, was done without the use of any as the patient had a history of severe intolerance to them. The case was an 83 year old male patient presenting with acute urinary retention. He was a known case of BPH being managed continuously on Ayurvedic therapy for many years...
November 17, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29149113/-incidence-of-surgical-site-infection-in-colon-surgery-and-antibiotic-prophylaxis-adequacy-prospective-cohort-study
#19
J A Del Moral Luque, M Alonso García, P Gil Yonte, J M Fernández Cebrián, M Durán Poveda, G Rodríguez Caravaca
BACKGROUND: Surgical site infection (SSI) has a considerable clinical and economic impact at the hospital level, so prevention and monitoring are considered a high priority. The objective of this study was to assess compliance with the protocol of antibiotic prophylaxis in colon surgery and the effect of its inadequacy for the incidence of SSI. METHODS: Prospective cohort study from July 2008 to July 2016. Compliance with antibiotic prophylaxis protocol and the causes of non-compliance were evaluated in colon surgery: duration and starting, choice, route of administration and dose of the antibiotic...
November 17, 2017: Anales del Sistema Sanitario de Navarra
https://www.readbyqxmd.com/read/29138696/use-of-common-inflammatory-markers-in-the-long-term-screening-of-total-hip-arthroprosthesis-infections-our-experience
#20
Gabriele Falzarano, Antonio Piscopo, Predrag Grubor, Giuseppe Rollo, Antonio Medici, Valerio Pipola, Michele Bisaccia, Auro Caraffa, Elizabeth Mary Barron, Francesco Nobile, Raffaele Cioffi, Luigi Meccariello
Orthopedic implants have become essential components of modern medicine. The risk of infection of total hip arthroplasty (THA) is 1.5%-2%. Are the C-reactive protein (CRP), the erythrocyte sedimentation rate (ESR), and procalcitonin (PCT) good markers for THA infection screenings? From February 2009 to December 2012 at our Department of Orthopedics and Traumatology, 1248 patients were treated with THA. No prosthesis was cemented. All patients received antibiotic prophylaxis. All patients were discharged approximately 7...
2017: Advances in Orthopedics
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