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infection prophylaxy surgery

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https://www.readbyqxmd.com/read/29902831/the-effect-of-antiseptics-in-the-prophylaxis-of-infection-in-orthopaedic-surgery
#1
Martin Lüdemann, Pablo Munoz, Martin Wagner, Uwe Malzahn, Konstantin Horas, Peter Heuschmann, Maximilian Rudert
INTRODUCTION: Over the past decade, the incidence of revision arthroplasty has increased substantially. One of the main reasons for revision arthroplasty is periprosthetic joint infection, often resulting in multiple surgical interventions with variable success and poor clinical outcome. Intraoperative wound irrigation has been proposed to reduce bacterial contamination and thus the risk of periprosthetic infection. However, there is currently no widely accepted recommendation for the use of topical antiseptics within the operative setting for primary implantation...
June 14, 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29887199/the-effectiveness-of-pedicle-screw-immersion-in-vancomycin-and-ceftriaxone-solution-for-the-prevention-of-postoperative-spinal-infection-a-prospective-comparative-study
#2
Burak Eren, Feyza Karagöz Güzey, Serkan Kitiş, Nezih Özkan, Cafer Korkut
OBJECTIVE: The aim of this study was to evaluate the efficacy of the local application of vancomycin hydrochloride (HCl)-ceftriaxone disodium hemiheptahydrate onto implants before using them to prevent postoperative infection. METHODS: The study included 239 patients (153 women and 86 men; mean age: 48.23 ± 16.77 years) who had thoracolumbar stabilization with transpedicular screws. All surgeries were performed by the same surgeon. Patients were divided into two groups...
June 7, 2018: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/29885873/prevention-of-deep-sternal-wound-infection-in-cardiac-surgery-review-of-literature
#3
REVIEW
Roemer J Vos, Bart P Van Putte, Geoffrey T L Kloppenburg
BACKGROUND: Deep sternal wound infection is a dreaded complication of cardiac surgery with considerable consequences in terms of mortality, morbidity and treatment costs. Multiple specific measures in the prevention of deep sternal wound infection have been developed and evaluated in the past decades in addition to standard surgical site infection prevention guidelines. This review focuses on these specific measures to prevent deep sternal wound infection. METHODS: An extensive literature search was performed to assess interventions in the prevention of deep sternal wound infection...
June 7, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29875091/relationship-between-staphylococcus-aureus-carriage-and-surgical-site-infections-following-total-hip-and-knee-arthroplasty-in-the-south-asian-population-protocol-for-a-prospective-cohort-study
#4
Syed H Mufarrih, Nada Q Qureshi, Anum Sadruddin, Pervaiz Hashmi, Syed Faisal Mahmood, Afia Zafar, Shahryar Noordin
BACKGROUND: Surgical site infections following total hip or knee arthroplasties have a reported rate of 0.49%-2.5% and can cause significant morbidity as well as tripling the cost of health care expenses. Both methicillin sensitive and methicillin resistant strains of Staphylococcus aureus surgical site infections have been established as a major risk factor for postoperative surgical site infections. S. aureus colonizes the nose, axillae, and perineal region in up to 20%-30% of individuals...
June 6, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29869780/prolonged-antibiotic-prophylaxis-after-thoracoabdominal-esophagectomy-does-not-reduce-the-risk-of-pneumonia-in-the-first-30-days-a-retrospective-before-and-after-analysis
#5
Marcel Hochreiter, Maria Uhling, Leila Sisic, Thomas Bruckner, Alexandra Heininger, Andreas Hohn, Katja Ott, Thomas Schmidt, Marc Moritz Berger, Daniel Christoph Richter, Markus Büchler, Markus Alexander Weigand, Cornelius Johannes Busch
PURPOSE: Thoracoabdominal esophageal resection for malignant disease is frequently associated with pulmonary infection. Whether prolonged antibiotic prophylaxis beyond a single perioperative dose is advantageous in preventing pulmonary infection after thoracoabdominal esophagectomy remains unclear. METHODS: In this retrospective before-and-after analysis, 173 patients between January 2009 and December 2014 from a prospectively maintained database were included. We evaluated the effect of a 5-day postoperative course of moxifloxacin, which is a frequently used antimicrobial agent for pneumonia, on the incidence of pulmonary infection and mortality after thoracoabdominal esophagectomy...
June 5, 2018: Infection
https://www.readbyqxmd.com/read/29808462/improvisation-versus-guideline-concordance-in-surgical-antibiotic-prophylaxis-a-qualitative-study
#6
Jennifer Broom, Alex Broom, Emma Kirby, Jeffrey J Post
PURPOSE: Surgical antibiotic prophylaxis (SAP) is a common area of antimicrobial misuse. The aim of this study was to explore the social dynamics that influence the use of SAP. METHODS: 20 surgeons and anaesthetists from a tertiary referral hospital in Australia participated in semi-structured interviews focusing on experiences and perspectives on SAP prescribing. Interview data were analysed using the framework approach. RESULTS: Systematic analysis of the participants' account of the social factors influencing SAP revealed four themes...
May 28, 2018: Infection
https://www.readbyqxmd.com/read/29794678/acog-practice-bulletin-no-195-prevention-of-infection-after-gynecologic-procedures
#7
(no author information available yet)
Surgical site infection remains the most common complication of gynecologic procedures. Reducing surgical site infections has become a priority in the United States as part of a strong national commitment to measuring processes and improving outcomes of care for surgery. Implementing programs to reduce surgical site infections requires a collaborative approach that involves clinicians, nurses, and staff. The purpose of this document is to review the recommended interventions, including antibiotic prophylaxis, used to prevent infection after gynecologic procedures...
June 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29794671/acog-practice-bulletin-no-195-summary-prevention-of-infection-after-gynecologic-procedures
#8
(no author information available yet)
Surgical site infection remains the most common complication of gynecologic procedures. Reducing surgical site infections has become a priority in the United States as part of a strong national commitment to measuring processes and improving outcomes of care for surgery. Implementing programs to reduce surgical site infections requires a collaborative approach that involves clinicians, nurses, and staff. The purpose of this document is to review the recommended interventions, including antibiotic prophylaxis, used to prevent infection after gynecologic procedures...
June 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29794586/evidence-based-care-bundles-for-preventing-surgical-site-infections-in-spinal-instrumentation-surgery
#9
Koji Yamada, Hiroaki Abe, Akiro Higashikawa, Juichi Tonosu, Takashi Kuniya, Koji Nakajima, Haruko Fujii, Kazuki Niwa, Tomohiro Shinozaki, Kenichi Watanabe, Tanaka Sakae, Hiroshi Okazaki
STUDY DESIGN: Retrospective study, using prospectively collected data. OBJECTIVE: To evaluate the impact of evidence-based care bundles for preventing surgical site infections (SSI) in spinal instrumentation surgery. SUMMARY OF BACKGROUND DATA: About half of all SSIs are preventable via evidence-based methods. For successful SSI prevention, the bacterial load must be minimized, and methicillin-resistant Staphylococcus aureus (MRSA) protection must be maximized...
May 22, 2018: Spine
https://www.readbyqxmd.com/read/29782303/clindamycin-induced-maculopapular-exanthema-with-preferential-involvement-of-striae-distensae-a-koebner-phenomenon
#10
Benigno Monteagudo, Miguel Cabanillas, Pilar Iriarte, Aquilina Ramírez-Santos, Elvira León-Muinos, Daniel González-Vilas, Óscar Suárez-Amor
Clindamycin is a lincomycin-derived antibiotic useful for the treatment of anaerobic and Gram-positive aerobic bacterial infections. Cutaneous adverse reactions are usually maculopapular exanthemas, although hypersensitivity syndrome, acute generalized exanthematous pustulosis, and Stevens-Johnson syndrome have also been reported (1). We report the case of a patient with a maculopapular rash triggered by clindamycin who developed cutaneous lesions on striae distensae (SD). A 47-year-old woman was referred to our clinic for pruritic cutaneous lesions which had started 6 days earlier...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29781787/evaluating-the-duration-of-prophylactic-post-operative-antibiotic-agents-after-open-reduction-internal-fixation-for-closed-fractures
#11
Brett D Crist, Lasun O Oladeji, Gregory J Della Rocca, David A Volgas, James P Stannard, David D Greenberg
BACKGROUND: The importance of timely pre-operative antibiotic agents for effective surgical prophylaxis has been established but the optimal duration of antimicrobial coverage post-operatively has not yet been defined clearly. The purpose of this study was to determine if prophylactic post- operative cefazolin for 23 hours decreases the risk of surgical site infection (SSI) after open reduction internal fixation (ORIF) of closed extremity fractures. PATIENTS AND METHODS: After Institutional Reviews Board approval, patients undergoing ORIF of closed extremity fractures who had a planned post-operative stay of at least 23 hours were randomly assigned to either receive 23 hours of cefazolin or a placebo...
May 21, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29780414/antibiotic-prophylaxis-with-trimethoprim-sulfamethoxazole-versus-no-treatment-after-mid-to-distal-hypospadias-repair-a-prospective-randomized-study
#12
Elizabeth B Roth, John V Kryger, Charles T Durkee, Melissa A Lingongo, Ruth M Swedler, Travis W Groth
Purpose: To evaluate the impact of prophylactic antibiotics after distal hypospadias repair on postoperative bacteriuria, symptomatic urinary tract infection, and postoperative complications in a prospective, randomized trial. Materials and Methods: Consecutive patients aged 6 months to 2 years were enrolled at our institution between June 2013 and May 2017. Consenting patients were randomized to antibiotic prophylaxis with trimethoprim-sulfamethoxazole versus no antibiotic...
2018: Advances in Urology
https://www.readbyqxmd.com/read/29773260/mechanical-bowel-preparation-and-oral-antibiotic-prophylaxis-in-colorectal-surgery-analysis-of-evidence-and-narrative-review
#13
Josep M Badia, Nares Arroyo-García
The role of oral antibiotic prophylaxis and mechanical bowel preparation in colorectal surgery remains controversial. The lack of efficacy of mechanical preparation to improve infection rates, its adverse effects, and multimodal rehabilitation programs have led to a decline in its use. This review aims to evaluate current evidence on antegrade colonic cleansing combined with oral antibiotics for the prevention of surgical site infections. In experimental studies, oral antibiotics decrease the bacterial inoculum, both in the bowel lumen and surgical field...
May 14, 2018: Cirugía Española
https://www.readbyqxmd.com/read/29772370/does-nasal-carriage-of-staphylococcus-aureus-increase-the-risk-of-post-operative-infections-after-elective-spine-surgery-do-most-infections-occur-in-carriers
#14
Owoicho Adogwa, Victoria D Vuong, Aladine A Elsamadicy, Daniel T Lilly, Shyam A Desai, Syed Khalid, Joseph Cheng, Carlos A Bagley
BACKGROUND: Wound infections following adult spinal deformity surgery place a high toll on patients, providers, and the healthcare system. Staphylococcus aureus is a common cause of postoperative wound infections, and nasal colonization by this organism may be an important factor development of surgical site infections (SSI's). The aim is to investigate whether post-operative surgical site infections after elective spine surgery occur at a higher rate in patients with Methicillin-Resistant Staphylococcus Aureus (MRSA) nasal colonization...
May 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29771900/inappropriate-prescribing-of-antibiotics-following-discharge-after-major-surgery-an-area-for-improvement
#15
Mary De Almeida, Catherine Gerard, Joshua T Freeman, Eamon Duffy, Sally A Roberts
AIM: This study aims to determine the indications for antibiotic use in patients discharged following major surgery at Auckland City Hospital (ACH); to determine if the indications were appropriate and to identify opportunities where antimicrobial stewardship interventions would be beneficial. METHODS: This was a retrospective study of adult patients who were dispensed an antibiotic within the first two days of discharge after major surgery at ACH between 1 January 2013 and 31 December 2013...
May 18, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29771856/vitamin-e-phosphate-coating-stimulates-bone-deposition-in-implant-related-infections-in-a-rat-model
#16
Arianna B Lovati, Marta Bottagisio, Susanna Maraldi, Martina B Violatto, Monica Bortolin, Elena De Vecchi, Paolo Bigini, Lorenzo Drago, Carlo L Romanò
BACKGROUND: Implant-related infections are associated with impaired bone healing and osseointegration. In vitro antiadhesive and antibacterial properties and in vivo antiinflammatory effects protecting against bone loss of various formulations of vitamin E have been demonstrated in animal models. However, to the best of our knowledge, no in vivo studies have demonstrated the synergistic activity of vitamin E in preventing bacterial adhesion to orthopaedic implants, thus supporting the bone-implant integration...
June 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29761139/prophylactic-antibiotics-after-stented-distal-hypospadias-repair-randomized-pilot-study
#17
Stephen Canon, Mary K Marquette, Adam Crane, Ashay Patel, Ismael Zamilpa, Shasha Bai
The usage of prophylactic oral antibiotics following distal hypospadias repair with stenting has been recently challenged. This study evaluated the incidence of symptomatic urinary tract infections (UTIs) following stented, distal hypospadias repair and the impact of prophylactic antibiotic therapy. Subjects 0 to 5 years of age with distal hypospadias were randomized to either Group 1 (antibiotics) or Group 2 (no prophylactic therapy). Urinalysis/urine culture was obtained intraoperatively with no preoperative antibiotics given...
2018: Global Pediatric Health
https://www.readbyqxmd.com/read/29756330/postoperative-prophylactic-antibiotics-for-facial-fractures-a-systematic-review-and-meta-analysis
#18
REVIEW
Andy M Habib, Alexander D Wong, Geoffrey C Schreiner, Komal F Satti, Natalie B Riblet, Heather A Johnson, Jacob P Ossoff
OBJECTIVE: Perioperative antibiotic prophylaxis in patients undergoing surgery for maxillofacial fractures is standard practice. However, the use of postoperative antibiotic prophylaxis remains controversial. This systematic review and meta-analysis sought to evaluate the effect of postoperative antibiotic therapy on the incidence of surgical site infection (SSI) in patients with maxillofacial fractures. METHODS: MEDLINE, Embase, and the Cochrane Library were searched from inception through October 2017...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29736803/titanium-granules-pre-treated-with-hydrogen-peroxide-inhibit-growth-of-bacteria-associated-with-post-operative-infections-in-spine-surgery
#19
Acke Ohlin, Emma Mattsson, Matthias Mörgelin, Julia R Davies, Gunnel Svensäter, Stéphane Corvec, Pentti Tengvall, Kristian Riesbeck
PURPOSE: Post-operative infections are relatively common after posterior spine surgery, and there are several observations reflecting different infection complications related to various metals implanted. Here, we selected an array of different bacterial species that are often found in infections associated with orthopaedic implants and tested for inhibition by hydrogen peroxide-treated titanium (Ti-peroxy). METHODS: To study the possibility of using Ti-peroxy as an antimicrobial prophylaxis, we developed a protocol for standardized susceptibility testing of bacteria...
May 7, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29726801/reduction-in-surgical-site-infection-with-suprafascial-intrawound-application-of-vancomycin-powder-in-instrumented-posterior-spinal-fusion-a-retrospective-case-control-study
#20
Shoichi Haimoto, Ralph T Schär, Yusuke Nishimura, Masahito Hara, Toshihiko Wakabayashi, Howard J Ginsberg
OBJECTIVE Recent studies have demonstrated the efficacy of subfascial intrawound application of vancomycin powder in spine surgery in reducing the rate of surgical site infections (SSIs). However, to date no study has evaluated the efficacy and safety of suprafascial application of vancomycin powder in spine surgery. The purpose of this study was to quantify the rate of SSIs after open instrumented posterior spinal fusion with and without application of suprafascial vancomycin powder and to evaluate the rate of vancomycin powder-related local adverse effects...
May 4, 2018: Journal of Neurosurgery. Spine
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