keyword
MENU ▼
Read by QxMD icon Read
search

DM and CAD

keyword
https://www.readbyqxmd.com/read/28065900/exploring-the-predictive-power-of-polygenic-scores-derived-from-genome-wide-association-studies-a-study-of-10-complex-traits
#1
Hon-Cheong So, Pak C Sham
MOTIVATION: It is hoped that advances in our knowledge in disease genomics will contribute to personalized medicine such as individualized preventive strategies or early diagnoses of diseases. With the growth of genome-wide association studies (GWAS) in the past decade, how far have we reached this goal? In this study we explored the predictive ability of polygenic risk scores (PRSs) derived from GWAS for a range of complex disease and traits. RESULTS: We first proposed a new approach to evaluate predictive performances of PRS at arbitrary P-value thresholds...
January 8, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28056847/impact-of-diabetes-and-hypertension-on-cardiovascular-outcomes-in-patients-with-coronary-artery-disease-receiving-percutaneous-coronary-intervention
#2
Mao-Jen Lin, Chun-Yu Chen, Hau-De Lin, Han-Ping Wu
BACKGROUND: Percutaneous coronary intervention (PCI) is a necessary procedure commonly performed for patients with coronary artery disease (CAD). However, the impact of diabetes and hypertension on long-term outcomes of patients after receiving PCI has not yet been determined. METHODS: The data of 1234 patients who received PCI were collected prospectively, and patients were divided into four groups, including patients with and without DM and those with either DM or hypertension alone...
January 5, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28045698/the-influence-of-metabolic-syndrome-and-diabetes-mellitus-on-the-n-terminal-pro-b-type-natriuretic-peptide-level-and-its-prognostic-performance-in-patients-with-coronary-artery-disease
#3
Fang-Yang Huang, Yong Peng, Xue-Xue Deng, Bao-Tao Huang, Tian-Li Xia, Yi-Yue Gui, Rui-Shuang Liu, Yong Yang, Xiao-Bo Pu, Shi-Jian Chen, Fei Chen, Ye Zhu, Mao Chen
OBJECTIVES: Our aim was to investigate whether the presence of metabolic syndrome (MetS) and diabetes mellitus (DM) influenced the N-terminal pro-B-type natriuretic peptide (NT-proBNP) level and its prognostic performance in coronary artery disease (CAD). PATIENTS AND METHODS: The present study enrolled a total of 1638 CAD patients. Multivariate regression analyses were carried out to relate NT-proBNP to metabolic components, nondiabetic MetS, DM, and MetS score...
December 29, 2016: Coronary Artery Disease
https://www.readbyqxmd.com/read/28029209/mortality-after-percutaneous-coronary-revascularization-prior-cardiovascular-risk-factor-control-and-improved-outcomes-in-patients-with-diabetes-mellitus
#4
Awsan Noman, Karthik Balasubramaniam, M Hafez A Alhous, Kelvin Lee, Peter Jesudason, Muhammad Rashid, Mamas A Mamas, Azfar G Zaman
OBJECTIVES: To assess the mortality in patients with diabetes mellitus (DM) following percutaneous coronary intervention (PCI) according to their insulin requirement and PCI setting (elective, urgent, and emergency). BACKGROUND: DM is a major risk factor to develop coronary artery disease (CAD). It is unclear if meticulous glycemic control and aggressive risk factor management in patients with DM has improved outcomes following PCI. METHODS: Retrospective analysis of prospectively collected data on 9,224 patients treated with PCI at a regional tertiary center between 2008 and 2011...
December 28, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28013282/fractional-flow-reserve-derived-from-coronary-computed-tomography-angiography-diagnostic-performance-in-hypertensive-and-diabetic-patients
#5
Ashkan Eftekhari, James Min, Stephan Achenbach, Mohamed Marwan, Matthew Budoff, Jonathon Leipsic, Sara Gaur, Jesper Møller Jensen, Brian S Ko, Evald Høj Christiansen, Anne Kaltoft, Hans Erik Bøtker, Jens Flensted Jensen, Bjarne Linde Nørgaard
AIMS: Fractional flow reserve (FFR) derived from coronary computed tomography (FFRCT) has high diagnostic performance in stable coronary artery disease (CAD). The diagnostic performance of FFRCT in patients with hypertension (HTN) and diabetes (DM), who are at risk of microvascular impairment, is not known. METHODS AND RESULTS: We analysed the diagnostic performance of FFRCT, in patients (vessels) with DM (n = 16), HTN (n = 186), DM + HTN (n = 58) vs...
December 24, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28009315/differences-in-ecg-characteristics-and-co-morbidities-among-patients-who-underwent-elective-surgical-repair
#6
I Botchorishvili, N Sharashidze, N Pargalava, Z Pagava, G Saatashvili
The aim of the study was to assess differences in ECG features and prevalence of comorbidies between two groups of patiens: with Abdominal Aortic Aneurism (AAA) and Aorto-Iliac Occlusive Desieses-Lerish Syndrome (LS). Data was collected for all consecutive adult patients who underwent elective surgical repair of AAA (fusiform aneurysm) or LS at "The Center of Vascular and Heart Diseases" (Tbilisi, Georgia) between 2010 and 2014. We studied a prevalence of Arterial Hypertension (AHT); Diabetes mellitus (DM); Renal Failure (RF),Peripheral Artery Disease (PAD), Coronary Artery Disease (CAD) and rate of coronary revascularization in these patients; We also, investigate some of the electrocariographic characteristics: Corrected QT interval(QTC),QT dispersion(QTD)...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/28002752/coronary-atherosclerosis-burden-by-coronary-computed-tomography-in-type-ii-diabetes-with-preclinical-non-obstructive-carotid-atherosclerosis-and-without-inducible-myocardial-ischemia
#7
Vittorio Palmieri, Enzo Gravino, Cesare Russo, Armenio Salvati, Carmelo Lombardi, Rosario Sauro, Giuseppe Rosato
AIMS: To quantify cardiovascular risk in persons with type-2 diabetes (DM) and established carotid atherosclerosis, without inducible myocardial ischemia by stress imaging. METHODS: We selected clinically healthy DM and subjects without DM (nonDM, controls) with non-obstructive carotid atherosclerosis and without significant coronary artery disease (CAD) by stress echocardiography. Coronary flow velocity reserve (CFR) was assessed during stress echocardiography...
December 5, 2016: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/27936195/plaque-characteristics-in-coronary-artery-disease-patients-with-impaired-glucose-tolerance
#8
Keishi Suzuki, Hitoshi Takano, Yoshiaki Kubota, Keisuke Inui, Shunichi Nakamura, Yukichi Tokita, Koji Kato, Kuniya Asai, Wataru Shimizu
BACKGROUND: Impaired glucose tolerance (IGT) patients are known to have a high risk of cardiovascular events and their prognosis has been reported to be poor. The present study aimed to compare coronary plaque characteristics among coronary artery disease (CAD) patients with normal glucose tolerance (NGT), those with IGT, and those with diabetes mellitus (DM) by using optical coherence tomography (OCT). METHODS: The present study included 101 coronary artery disease patients (mean age, 67...
2016: PloS One
https://www.readbyqxmd.com/read/27932342/time-saving-screening-for-diabetes-in-patients-with-coronary-artery-disease-a-report-from-euroaspire-iv
#9
Viveca Gyberg, Dirk De Bacquer, Kornelia Kotseva, Guy De Backer, Oliver Schnell, Jaakko Tuomilehto, David Wood, Lars Rydén
BACKGROUND: WHO advocates 2-hour oral glucose tolerance test (OGTT) for detecting diabetes mellitus (DM). OGTT is the most sensitive method to detect DM in patients with coronary artery disease (CAD). Considered time consuming, the use of OGTT is unsatisfactory. A 1-hour plasma glucose (1hPG) test has not been evaluated as an alternative in patients with CAD. OBJECTIVES: To create an algorithm based on glycated haemoglobin (HbA1c), fasting plasma glucose (FPG) and 1hPG limiting the need of a 2-hour plasma glucose (2hPG) in patients with CAD...
December 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/27894255/silent-diabetic-cardiomyopathy-in-everyday-practice-a-clinical-and-echocardiographic-study
#10
Brane Loncarevic, Danijela Trifunovic, Ivan Soldatovic, Bosiljka Vujisic-Tesic
BACKGROUND: Whether type 2 diabetes mellitus (DM) in the absence of hypertension (HTA) and coronary artery disease (CAD) affects left ventricular (LV) phenotype and function among asymptomatic DM patients that can be easily discovered in everyday practice, what is the clinical risk profile for diabetic cardiomyopathy and how HTA and CAD modulate LV structure and function above diabetic cardiomyopathy, are still incompletely answered questions. METHODS: In 210 DM patients (group I: 70 asymptomatic DM patients without HTA and CAD; group II: 70 DM patients with HTA and no CAD; group III: 70 DM patients with CAD and no HTA) and 80 healthy individuals, comprehensive echocardiography including speckle tracking strain and strain rate analysis, was done...
November 29, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27873498/the-impact-of-diabetes-mellitus-on-vascular-biomarkers-in-patients-with-end-stage-renal-disease
#11
Jeonggeun Moon, Chan Joo Lee, Sang Hak Lee, Seok Min Kang, Donghoon Choi, Tae Hyun Yoo, Sungha Park
PURPOSE: Diabetes mellitus (DM) is the most common cause of end-stage renal disease (ESRD) and an important risk factor for cardiovascular (CV) disease. We investigated the impact of DM on subclinical CV damage by comprehensive screening protocol in ESRD patients. MATERIALS AND METHODS: Echocardiography, coronary computed tomography angiogram, 24-h ambulatory blood pressure monitoring, and central blood pressure with pulse wave velocity (PWV) were performed in 91 ESRD patients from the Cardiovascular and Metabolic disease Etiology Research Center-HIgh risk cohort...
January 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27832749/type-2-diabetes-compromises-the-value-of-non-invasively-measured-augmentation-index-in-predicting-the-severity-of-coronary-artery-disease-a-hospital-based-observational-study
#12
Sijing Wu, Yujie Zhou, Yueping Li, Yuyang Liu, Dongmei Shi, Xiaoli Liu, Wei Liu, Yi Yu, Shuo Jia
BACKGROUND: Central hemodynamic indices have been demonstrated to correlate with coronary artery disease (CAD). However, in the context of type 2 diabetes mellitus (DM), this correlation has not been fully illustrated. Therefore, this study was employed to investigate the impact of DM on the correlation between aortic augmentation index and the severity of coronary artery disease. METHODS: In this study, we analyzed 197 patients who underwent coronary angiography at Anzhen Hospital from September 2015 to January 2016...
November 10, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27805331/a-prospective-study-on-utility-of-exercise-treadmill-test-in-type-2-diabetes-mellitus-patients
#13
Meenaxi Sharda, Anil Kumar Soni, Shivraj Meena, Harish Nigam, Anuraj Singh
OBJECTIVE: Primary objective of this study was to access utility of exercise treadmill test in type-2 diabetes mellitus patients for detecting silent myocardial ischaemia and associated risk factors. METHODS: 75 DM-2 cases were enrolled in study of any age attending medical OPD. All cases were gone through detailed history and TMT procedure. RESULTS: There is higher prevalence of SMI in DM-2 patients. TMT positivity for inducible ischaemia in DM-2 patients were associated with increasing age, male sex, higher BMI, hypertension, smoking, alcoholism, microalbuminuria, macroalbuminuria and dyslipidemia...
November 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27784448/-effects-and-underlying-mechanism-of-berberine-on-renal-tubulointerstitial-injury-in-diabetic-rats
#14
Z J Ma, S L Hu, S S Wang, X Guo, X N Zhang, B Sun, L M Chen
Objective: To investigate the effect of Berberine on renal tubulointerstitial injury and its potential mechanism in rats with type 2 diabetes mellitus (T2DM). Methods: Thirty Sprague-Dawley rats were randomly divided into 3 groups: normal control rats (NC group), diabetic rats without drug treatment (DM group), diabetic rats treated with Berberine (BBR group) for 8 weeks. At the end of the study, blood and urine samples were collected for biochemical examination, and tubulointerstitial fibrosis was quantified by Hematoxylin and Eosin (HE) and Masson staining...
October 18, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27781059/relationship-of-lipid-and-lipoprotein-ratios-with-coronary-severity-in-patients-with-new-on-set-coronary-artery-disease-complicated-with-type-2-diabetics
#15
Ying Du, Juan Chen, Man-Hua Chen, Sheng-Hua Yang, Sha Li, Yuan-Lin Guo, Cheng-Gang Zhu, Rui-Xia Xu, Qian Dong, Jian-Jun Li
BACKGROUND: Diabetes mellitus (DM) is associated with coronary artery disease (CAD) progression. Although previous studies have demonstrated the association of lipid and lipoprotein ratios with CAD, no data are currently available concerning the relationship between lipid and lipoprotein ratios and the severity of new on-set CAD in diabetics. Therefore, the aim of the present study was to investigate the usefulness of lipid and lipoprotein ratios in predicting the severity of CAD in patients with type 2 DM (T2DM)...
August 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/27766800/cardiometabolic-risk-factors-in-acute-coronary-syndrome-with-special-reference-to-non-hdl-cholesterol
#16
Debjani S Goswami, Tanuja P Manohar
INTRODUCTION: Cardiovascular diseases are becoming the major cause of morbidity and mortality in most of the developing countries including India. Cardiometabolic risk factors play a vital role in causation of coronary artery disease. Present study was carried out to investigate the role of various risk factors in the occurrence of coronary artery disease (CAD) in population from Central India. SETTING AND DESIGN: This was a hospital-based age and sex matched case-control study, carried out at Lata Mangeshkar Hospital, Nagpur...
October 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27728104/study-of-asymptomatic-peripheral-arterial-disease-in-type-2-dm-patients-its-correlation-with-cad
#17
Mayur Agrawal, Preksha Dwivedi, V K Sharma, T N Dubey
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27666175/diabetes-invoked-high-density-lipoprotein-and-its-association-with-coronary-artery-disease-in-patients-with-type-2-diabetes-mellitus
#18
Jia Teng Sun, Yan Liu, Lin Lu, Hong Juan Liu, Wei Feng Shen, Ke Yang, Rui Yan Zhang
Although high-density lipoprotein (HDL) can exhibit anti-inflammatory properties, these potent activities can become deficient and even transform into proinflammatory effects under various pathophysiological states. We investigated the effect of diabetic HDL on the inflammatory response in human monocytes and its relation to the existence of coronary artery disease (CAD) in patients with type 2 diabetes mellitus (DM). HDL was isolated from DM patients with (n = 61) or without (n = 31) CAD (diameter stenosis ≥50%) and healthy controls (n = 40)...
August 30, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27665101/combined-aspirin-and-anticoagulant-therapy-in-patients-with-atrial-fibrillation
#19
Charlotte H So, Mark H Eckman
The combined use of aspirin and oral anticoagulant therapy in patients with atrial fibrillation (AF) and stable coronary artery disease (CAD) has been questioned due to an increased risk of major bleeding with little to no benefit in preventing ischemic events. (1) To better understand patterns and indications for combined antiplatelet and anticoagulant therapy and identify patients who might reasonably be treated with oral anticoagulant (OAC) therapy alone. (2) To perform an updated literature review regarding the use of combined antiplatelet and OAC therapy in patients with AF and stable CAD...
January 2017: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/27617506/comparative-evaluation-of-dyslipedaemia-in-obese-and-diabetic-patients-of-rural-and-urban-areas-in-lahore-pakistan
#20
R Akhtar, H Ahmed, M N Afzal, H R Rehman, I Rashid, S Imran
Objective: Obesity and diabetes mellitus (DM) are interconnected conditions that share a number of pathophysiological mechanisms such as dyslipidaemia leading to cardiovascular complications. The present study was conducted to determine the individual and combined effect of DM and obesity on dyslipidaemia and ultimately on silent coronary artery disease (CAD). Methods: The patients selected from urban and rural areas of Lahore were recruited on the basis of body mass index (BMI) and fasting blood sugar (FBS) and were classified in four groups: (Group A; obese-diabetic, Group B; non-obese and diabetic, Group C; obese and non-diabetic and Group D; non-obese and non-diabetic)...
March 16, 2016: West Indian Medical Journal
keyword
keyword
118053
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"