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transcutaneous aortic valve replacement

Athanasios Antoniou, Amer Harky, Mohamad Bashir, Gebrine El Khoury
Aortic valve replacement whether surgical or transcutaneous remains an option for the treatment of severe aortic valve disease; however, current prosthetic devices are associated with complications including, but no limited to, valve thrombosis and thromboembolic events, bleeding events associated with anticoagulation use, prosthetic valve endocarditis and structural valve deterioration. In this effect, aortic valve repair (AVr) has become an attractive alternative in circumventing these potential complications by preservation of the native aortic valve apparatus...
April 5, 2018: General Thoracic and Cardiovascular Surgery
Samuel Latham, Tamunoinemi Bob-Manuel, Arindam Sharma, Amit Nanda, Devareshi Ardeshna, Rami N Khouzam
Aortic stenosis (AS) is a common cause of valvular heart disease with heavy disease burden in elderly patients. It is present in almost 7% of patients older than 65. The mortality rate increases significantly once it becomes symptomatic with average life expectancy of around 1-year. Symptoms include angina, syncope, or heart failure. This requires either surgical or transcutaneous replacement. Transcutaneous aortic valve replacement (TAVR) use has increased in recent years from high risk patients to now even including intermediate risk patients...
January 2018: Annals of Translational Medicine
Zdenek Provaznik, Andreas Holzamer, Daniele Camboni, Leopold Rupprecht, Markus Resch, Sigrid Wittmann, Christof Schmid, Bernhard Floerchinger
Background: Less invasive procedures have replaced open surgical treatment in many cardiovascular disorders. During these interventions, iatrogenic cardiac perforation may ensue, which is a severe complication and requires immediate diagnostic assessment and treatment. Methods: From March 2011 to April 2016, all patients referred to the Dept. of Cardio-thoracic Surgery with the diagnosis of iatrogenic perforation of myocardial wall or great vessels were included into the retrospective study...
December 2017: Journal of Thoracic Disease
Vanya Jaitly, Kimberly Klein, Hlaing Tint, Alice Chen, Paul Allison, Bindu Akkanti, Pranav Loyalka, Brian Castillo
Perioperative bleeding can be a serious life-threatening complication in adult patients undergoing cardiac surgery, given the older age and additional comorbidities present in this patient population. The standard treatment options include transfusion of blood components and surgical re-exploration. We report the first case of an elderly female patient treated with local administration of recombinant factor VIIa (rFVIIa) for intractable hemorrhagic pericardial effusion, which developed following a transcutaneous aortic valve replacement (TAVR) procedure for severe aortic stenosis...
August 1, 2017: Laboratory Medicine
Padmini Varadarajan, Ramdas G Pai
No abstract text is available yet for this article.
May 2017: Echocardiography
Kathirvel Subramaniam, Soheyla Nazarnia
Prosthesis-patient Mismatch (PPM) is not uncommon with an incidence reported up to 70% after aortic valve (AV) replacement. Severe forms of PPM are less common (up to 20%); PPM can lead to increased short- and long-term morbidity and mortality. It is important to discriminate PPM from other forms of prosthetic valve dysfunction. Sometimes, prosthetic valve degenerative disease may coexist with PPM. Echocardiography plays an important role in the prevention and diagnosis of PPM. Preemptive strategies to prevent PPM include insertion of newer generation prosthetic valves with better hemodynamic characteristics, stentless prosthesis, aortic root enlargement to insert a larger prosthesis, aortic homograft, and transcutaneous AV implantation...
April 2017: Annals of Cardiac Anaesthesia
Shinichi Takamoto
In the recent decade medicine developed far beyond people's mind, as transcutaneous aortic valve replacement(TAVR), Mitraclip et al. As recent development of information technology has changed to real time information system in the world, international communication in the field of cardiovascular surgery has also changed to become large in volume, rapid in time and frequent and convenient in use. The Asian Society for Cardiovascular and Thoracic Surgery(ASCVTS) which has a major role of international communication in the field cardiovascular surgery in Japan, has developed to become one of the major international academic society...
January 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Phuong L Markman, John-Paul Tantiongco, Jayme S Bennetts, Robert A Baker
BACKGROUND: Postoperative serum troponin levels and perioperative myocardial infarction (MI) rates correlate with mortality and morbidity following cardiac surgery. The objective of this study was to document the release profile of high sensitivity troponin T (hsTnT) following different cardiac operations. METHODS: Patients undergoing one of five different isolated cardiac surgical procedures (eligible preoperative hsTnT <29ng/L, serum creatinine < 0.2mmol/L) were recruited prospectively...
August 2017: Heart, Lung & Circulation
Gregg S Pressman
No abstract text is available yet for this article.
2017: Cardiology
James D Thomas
No abstract text is available yet for this article.
August 1, 2016: JAMA Cardiology
Jakub Sulženko, Petr Toušek, Viktor Kočka, František Bednář, Hana Línková, Robert Petr, Marek Laboš, Petr Widimský
BACKGROUND: Little is known about the valve degeneration process after transcutaneous aortic valve implantations (TAVI) that can have an important impact on patients' long-term prognosis. AIM: To evaluate degenerative changes of TAVI using computed tomography (CT) compared to findings in patients that underwent surgical aortic valve replacement (SAVR). Subsequently, to compare the level of immune and inflammatory markers in both groups and test their possible role in the valve degeneration process...
February 2017: Journal of Cardiology
Tomas A Salerno, Alexandre C Ferreira
No abstract text is available yet for this article.
December 2015: Journal of Thoracic and Cardiovascular Surgery
Thibault Caspar, Laurence Jesel, Dominique Desprez, Lélia Grunebaum, Hafida Samet, Annie Trinh, Hélène Petit-Eisenmann, Michel Kindo, Patrick Ohlmann, Olivier Morel
BACKGROUND: Aortic valve stenosis (AVS) can be complicated by bleeding associated with acquired type 2A von Willebrand syndrome. The association of AVS and gastrointestinal bleeding from angiodysplasia is defined as Heyde syndrome. We sought to evaluate the effect of transcutaneous aortic valve implantation (TAVI) on hemostasis disorders and to assess its effectiveness to treat Heyde syndrome. METHODS: We prospectively enrolled 49 consecutive patients with severe AVS addressed for TAVI at our institution...
June 2015: Canadian Journal of Cardiology
Igor Volodarsky, Sara Shimoni, Jacob George
Transcatheter aortic valve implantation (TAVI) is a relatively novel procedure first performed in 2002 and has undergone rapid development since then. Its main indication is treatment of severe symptomatic aortic valve stenosis. Initially, the procedure was indicated for very sick patients who were not eligible for surgical aortic valve replacement. However, rapid development of the technology and operator skill required for TAVI allowed widening of the indications for its use. Currently, there is evidence that TAVI could be better than the surgical intervention in a broad population and not only in the most sick...
October 2014: Expert Review of Cardiovascular Therapy
Stewart Michael Benton, Anupam Kumar, Marshall Crenshaw, Joseph L Fredi
The association between aortic valve stenosis and gastrointestinal bleeding, traditionally known as Heyde's syndrome, is the result of a quantitative loss of the highest molecular weight von Willebrand multimers (type 2A von Willebrand syndrome). This results in bleeding from areas of high shear stress such as gastrointestinal angiodysplasias. Correction of this bleeding diathesis after surgical aortic valve replacement has been well described. The effect of transcutaneous aortic valve implantation on Heyde's syndrome has yet to be studied...
September 15, 2014: American Journal of Cardiology
Natesa G Pandian, Alamelu Ramamurthi, Sarah Applebaum
Aortic stenosis is a valve disorder that includes not only valve narrowing but also changes in the left ventricle and intracardiac hemodynamics. Older patients with aortic stenosis often have co-existing pathologic disorders, which influence the pathophysiology, symptom expression and prognosis. There is also increasing awareness that severe aortic stenosis could be associated with low transvalvular pressure gradient caused by a variety of mechanisms. Surgical and transcutaneous valve replacements are currently available interventions for patients with severe aortic stenosis...
July 2014: Progress in Cardiovascular Diseases
Friedrich W Mohr, David Holzhey, Helge Möllmann, Andreas Beckmann, Christof Veit, Hans Reiner Figulla, Jochen Cremer, Karl-Heinz Kuck, Rüdiger Lange, Ralf Zahn, Stefan Sack, Gerhard Schuler, Thomas Walther, Friedhelm Beyersdorf, Michael Böhm, Gerd Heusch, Anne-Kathrin Funkat, Thomas Meinertz, Till Neumann, Konstantinos Papoutsis, Steffen Schneider, Armin Welz, Christian W Hamm
OBJECTIVES: The German Aortic Valve Registry (GARY) seeks to provide information on a real-world, all-comers basis for patients undergoing aortic valve interventions. This registry comprises patients undergoing the complete spectrum of transcutaneous and conventional surgical aortic valve interventions. The aim of this study was to use the GARY registry to evaluate conventional and catheter-based aortic valve interventions in several risk groups. METHODS: A total of 13 860 consecutive patients undergoing intervention for aortic valve disease [conventional aortic valve replacement (AVR) or transvascular/transapical TAVR (TV-/TA-TAVR)] were enrolled in 78 German centres in 2011...
November 2014: European Journal of Cardio-thoracic Surgery
Rebecca T Hahn, Susheel Kodali, Philippe Généreux, Martin Leon
Despite the higher incidence of paravalvular regurgitation (PVR) with transcatheter aortic valve replacement (TAVR), this novel treatment modality has rapidly emerged as a reasonable alternative to surgical aortic valve replacement (SAVR) in high risk and inoperable patients. This review will discuss the current literature with respect to assessment, outcomes, predictors, and intraprocedural treatment options of PVR following TAVR. Understanding the predictors may help reduce the incidence of PVR and improving the outcome of this procedure...
May 2014: Current Cardiology Reports
David M Shavelle
No abstract text is available yet for this article.
May 2014: Heart: Official Journal of the British Cardiac Society
Martin Greif, Philipp Lange, Michael Näbauer, Florian Schwarz, Christoph Becker, Christoph Schmitz, Tilmann Pohl, Melvin D'Anastasi, Peter Boekstegers, Steffen Massberg, Christian Kupatt
OBJECTIVE: To assess the feasibility of transcatheter aortic valve implantation (TAVI; Medtronic CoreValve and Edwards SAPIEN XT) under local anaesthesia with only mild analgesic medication and fluoroscopic guidance. METHODS: 461 patients underwent TAVI under local anaesthesia with lidocaine. The procedure was performed successfully in 459 of the cases. All patients were also treated with piritramide, metoclopramide hydrochloride and 62 mg dimenhydrinate. Monitoring consisted of a six-electrode, virtual 12-lead ECG, pulse oximetry, and invasive arterial pressure measurement...
May 2014: Heart: Official Journal of the British Cardiac Society
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