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https://www.readbyqxmd.com/read/29347956/what-should-be-included-in-the-assessment-of-laypersons-paediatric-basic-life-support-skills-results-from-a-delphi-consensus-study
#1
Asbjørn Børch Hasselager, Torsten Lauritsen, Tim Kristensen, Cathrine Bohnstedt, Claus Sønderskov, Doris Østergaard, Martin Grønnebæk Tolsgaard
BACKGROUND: Assessment of laypersons' Paediatric Basic Life Support (PBLS) skills is important to ensure acquisition of effective PBLS competencies. However limited evidence exists on which PBLS skills are essential for laypersons. The same challenges exist with respect to the assessment of foreign body airway obstruction management (FBAOM) skills. We aimed to establish international consensus on how to assess laypersons' PBLS and FBAOM skills. METHODS: A Delphi consensus survey was conducted...
January 18, 2018: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/29337721/continuing-play-symptom-severity-and-symptom-duration-after-concussion-in-youth-athletes
#2
David R Howell, Michael J OʼBrien, Joana Fraser, William P Meehan
OBJECTIVE: To determine whether continuing to play after a concussion is associated with higher symptom burden or prolonged symptom duration. DESIGN: Patients who presented for care at a sport concussion clinic within the first 3 weeks of injury were asked whether they continued to play immediately after their injury. SETTING: Sport concussion clinic within a regional tertiary care hospital. MAIN OUTCOME MEASURES: Clinical outcomes including symptom severity, symptom duration, age, time from injury-clinical presentation, sex, sport type, previous concussion history, and whether or not they experienced loss of consciousness or amnesia at the time of injury were recorded...
January 15, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29331713/repeated-attempted-homicide-by-administration-of-drugs-documented-by-hair-analysis
#3
Valérie Baillif-Couniou, Christophe Bartoli, Caroline Sastre, Marjorie Chèze, Marc Deveaux, Georges Léonetti, Anne-Laure Pélissier-Alicot
Attempted murder by repeated poisoning is quite rare. The authors describe the case of a 62-year-old man who was admitted to an intensive care unit (ICU) for neurological disturbances complicated by inhalation pneumopathy. He presented a loss of consciousness while his wife was visiting him at the ICU (H0). Forty-eight hours later (H48), police officers apprehended the patient's wife pouring a liquid into his fruit salad at the hospital. Toxicological analyses of a blood sample and the infusion equipment (H0), as well as the fruit salad and its container (H48), confirmed the attempted poisoning with cyamemazine (H0) and hydrochloric acid (H48)...
January 5, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29325790/how-do-oral-and-maxillofacial-surgeons-manage-concussion
#4
D Hammond, R Welbury, G Sammons, E Toman, M Harland, S Rice
Craniofacial trauma results in distracting injuries that are easy to see, and as oral and maxillofacial surgeons (OMFS) we gravitate towards injuries that can be seen and are treatable surgically. However, we do tend not to involve ourselves (and may potentially overlook) injuries that are not obvious either visually or radiographically, and concussion is one such. We reviewed the records of 500 consecutive patients who presented with facial fractures at the Queen Elizabeth Hospital, Birmingham, to identify whether patients had been screened for concussion, and how they had been managed...
January 8, 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29324792/critical-evaluation-of-colon-submucosal-microdialysis-in-awake-mobile-rats
#5
Norbert Cibicek, Jiri Ehrmann, Jitka Proskova, Rostislav Vecera
Sensors able to record large bowel physiology and biochemistry in situ in awake rodents are lacking. Microdialysis is a mini-invasive technique that may be utilized to continuously deliver or recover low-molecular substances from various tissues. In this experiment we evaluated the feasibility of in vivo microdialysis to monitor extracellular fluid chemistry in the descending colon submucosa of conscious, freely moving rodents. Following surgical implantation of a microdialysis probe, male Wistar rats were housed in metabolic cages where they were analgized and clinically followed for four days with free access to standard diet and water...
2018: PloS One
https://www.readbyqxmd.com/read/29323630/fatal-innominate-artery-hemorrhage-in-a-patient-with-tetraplegia-case-report-and-literature-review
#6
Ahmad Zaheer Qureshi
Context Hemorrhage is one of the potentially fatal complications of tracheostomy. A rare but lethal cause of tracheostomy related bleeding is hemorrhage from the innominate artery. This occurs following tracheo-innominate artery fistula (TIF) formation, which is associated with a mortality rate of more than 85%. Here, we report the case of an individual with tetraplegia and a tracheostomy who died as a result of innominate artery hemorrhage. This case highlights the possible causes and interventions associated with this complication, and provides insight into tracheostomy related bleeding in patients with spinal cord injury (SCI)...
January 11, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29315578/hcn4-pacemaker-channels-attenuate-the-parasympathetic-response-and-stabilize-the-spontaneous-firing-of-sinoatrial-node
#7
Yuko Kozasa, Noriyuki Nakashima, Masayuki Ito, Taisuke Ishikawa, Hiroki Kimoto, Kazuo Ushijima, Naomasa Makita, Makoto Takano
The heart rate is dynamically controlled by the sympathetic and parasympathetic nervous systems that regulate the sinoatrial node (SAN). HCN4 pacemaker channels are well-known causative molecule of congenital sick sinus syndrome. Although HCN4 channels are activated by cAMP, the sympathetic response of SAN was preserved in the patients carrying loss-of-function mutations of HCN4 gene. In order to clarify the contribution of HCN4 channels in the autonomic regulation of SAN, we developed novel gain-of-function mutant mice in which expression level of HCN4 channels could be reversibly changed from zero to ∼3 times of that in wild type mice, using tetracycline trans-activator and tetracycline responsive element...
January 9, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29310486/focal-segmental-glomerulosclerosis-in-children-complicated-by-posterior-reversible-encephalopathy-syndrome
#8
Magdalena Stârcea, Cristina Gavrilovici, Mihaela Munteanu, Ingrith Miron
An uncommon side effect of cyclosporine A (CsA) use is posterior reversible encephalopathy syndrome (PRES). PRES usually develops because of disturbed capacity of posterior cerebral blood flow to autoregulate an acute rise in blood pressure. We present the case of a 10-year-old girl who was previously diagnosed in our department with focal segmental glomerulosclerosis. She was treated with CsA and developed seizures, progressive loss of consciousness, and visual disturbance on the 7th day of treatment. Brain magnetic resonance imaging showed degeneration of white matter with diffuse demyelination in the parietal and posterior occipital lobes, consistent with the diagnosis of PRES...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29304117/associations-between-self-reported-lifetime-history-of-traumatic-brain-injuries-and-current-disability-assessment-in-a-population-sample-of-canadian-adults
#9
Gabriela Ilie, Edward M Adlaf, Robert E Mann, Anca Ialomiteanu, Hayley Hamilton, Jürgen Rehm, Mark Asbridge, Michael D Cusimano
OBJECTIVE: This study describes the association between history of lifetime traumatic brain injury (TBI) and current disabling functional restrictions among Ontario adults. SETTING AND DESIGN: A two-stage rolling cross-sectional sample of 6,048 adults aged 18 to 93 were interviewed by computer assisted telephone interviewing between 2011-2013 regarding their mental health and substance use in Ontario, Canada. TBI criteria were defined by loss of consciousness for minimum five minutes or at least one overnight hospitalization...
2018: PloS One
https://www.readbyqxmd.com/read/29303111/chronic-implantation-of-cuff-electrodes-on-the-pelvic-nerve-in-rats-is-well-tolerated-and-does-not-compromise-afferent-or-efferent-fibre-functionality
#10
Jonathan J Crook, Charly Brouillard, Pedro Irazoqui, Thelma Lovick
Objective Neuromodulation of autonomic nerve activity to regulate physiological processes is an emerging field. Vagal stimulation has received most attention whereas the potential of modulate visceral function by targeting autonomic nerves within the abdominal cavity remains under-exploited. Surgery to locate intra-abdominal targets is inherently more stressful than for peripheral nerves. Electrode leads risk becoming entrapped by intestines and loss of functionality in the nerve-target organ connection could result from electrode migration or twisting...
January 5, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29297196/psychophysiological-evaluation-of-patients-with-transient-loss-of-consciousness-of-uncertain-origin
#11
Donatella Brisinda, Lara La Brocca, Anna Rita Sorbo, Gianmarco Lombardi, Francesco Fioravanti, Riccardo Fenici
BACKGROUND: Psychological profile (PsyP) of patients with transient loss of consciousness (TLoC) evidences high prevalence of anxiety and depression. However, the mechanistic link between abnormal PsyP and TLoC is still unclear. AIM: This study aimed at evaluating: 1) prevalence of abnormal PsyP in TLoC patients; 2) cardiac autonomic response to Head-up Tilt Test (HUTT) in patients with (PsyP+) or without abnormal PsyP (PsyP-), developing syncope (HUTT+) or not (HUTT-)...
January 3, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29288749/enhanced-wakefulness-following-lesions-of-a-mesopontine-locus-essential-for-the-induction-of-general-anesthesia
#12
Sa'ar Lanir-Azaria, Guy Meiri, Tamir Avigdor, Anne Minert, Marshall Devor
The induction of general anesthesia shares many features with the transition from wakefulness to non-rapid eye movement (NREM) sleep, suggesting that the two types of brain-state transition are orchestrated by a common neuronal mechanism. Previous studies revealed a brainstem locus, the mesopontine tegmental anesthesia area (MPTA), that is of singular importance for anesthetic induction. Microinjection there of GABAergic anesthetics induces rapid loss-of-consciousness and lesions render the animal relatively insensitive to anesthetics administered systemically...
December 27, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29286838/patients-self-esteem-before-and-after-chemical-peeling-procedure
#13
Kouris Anargyros, Platsidaki Eftychia, Christodoulou Christos, Efstathiou Vasiliki, Markantoni Vasiliki, Armyra Kaliopi, Potouridou Irene, Rigopoulos Dimitrios, Kontochristopoulos George
INTRODUCTION: Chemical peeling is a safe method, widely used to treat a variety of skin conditions and reduce the aging effects. This study aims to evaluate self-esteem among adolescents who undergo chemical peelings. MATERIAL AND METHODS: One hundred and twenty six patients constituted the study group. Sixty seven individuals had undergone chemical peeling for therapeutic reasons and 59 individuals for cosmetic reasons. To assess patients' self-esteem, the Rosenberg's Self-esteem Scale (RSES) was used before and after treatment...
December 29, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29284874/low-dose-succinylcholine-to-facilitate-laryngeal-mask-airway-insertion-a-comparison-of-two-doses
#14
Leah R George, Raj Sahajanandan, Sarah Ninan
Background and Aims: Around the world, the use of the laryngeal mask airway (LMA) is becoming more common for different surgeries accounting for it being the dominant choice of airway in numerous surgeries. Although propofol is known to blunt the laryngeal reflexes often patient movement, coughing, and gagging occur on insertion. This study aims to identify the optimum dose of succinylcholine required to facilitate LMA insertion comparing placebo, 0.1 mg/kg and 0.25 mg/kg of succinylcholine...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29281194/the-dewey-monitor-pulse-oximetry-can-independently-detect-hypoxia-in-a-rebreather-diver
#15
Rachel M Lance, Michael J Natoli, Sophia A S Dunworth, John J Freiberger, Richard E Moon
Rebreather diving has one of the highest fatality rates per man hour of any diving activity in the world. The leading cause of death is hypoxia, typically from equipment or procedural failures. Hypoxia causes very few symptoms prior to causing loss of consciousness. Additionally, since the electronics responsible for controlling oxygen levels in rebreathers often control their alarm systems, frequently divers do not receive any external warnings. This study investigated the use of a forehead pulse oximeter as an independent warning device in the event of rebreather failure...
November 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29277588/sport-related-traumatic-brain-injury-with-and-without-helmets-in-children
#16
Angela Bandte, Friederike-Sophie Fritzsche, Pedram Emami, Getrud Kammler, Klaus Püschel, Kara Krajewski
BACKGROUND: Soccer, bicycling and horseback riding are sports most commonly associated with traumatic brain injury (TBI) in Germany. The latter are commonly practiced with helmets and data on helmet use and usefulness vary widely. METHODS: After ethics approval, retrospective analysis was performed for patients ages 5-17 from 01/2009- 08/2014 based on the diagnosis TBI using the electronic patient file for both university hospital locations. Descriptive data analysis, multi- and univariate logistic regression were employed to calculate the odds ratio...
December 22, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29274102/effect-of-age-on-narcotrend-index-monitoring-during-sevoflurane-anesthesia-in-children-below-2%C3%A2-years-of-age
#17
Nils Dennhardt, Stefanie Arndt, Christiane Beck, Dietmar Boethig, Sebastian Heiderich, Barbara Schultz, Frank Weber, Robert Sümpelmann
BACKGROUND: In older children, different electroencephalogram-based algorithms for measuring depth of anesthesia displayed a similar performance as in adults, but in infants they have not displayed the same reliability so far. According to the individual developmental state, the Narcotrend distinguishes "differentiated" electroencephalograms, which can be classified using the full Narcotrend Index scale, from "undifferentiated" electroencephalograms, which are classified using a scale with fewer stages...
December 23, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/29258788/anaphylactic-reactions-after-discontinuation-of-hymenoptera-venom-immunotherapy-a-clonal-mast-cell-disorder-should-be-suspected
#18
Patrizia Bonadonna, Roberta Zanotti, Mauro Pagani, Massimiliano Bonifacio, Luigi Scaffidi, Elisa Olivieri, Maurizio Franchini, Federico Reccardini, Maria Teresa Costantino, Chiara Roncallo, Marina Mauro, Elisa Boni, Fabio Lodi Rizzini, Maria Beatrice Bilò, Anna Rosaria Marcarelli, Giovanni Passalacqua
BACKGROUND: Up to 75% of patients with severe anaphylactic reactions after Hymenoptera sting are at risk of further severe reactions if re-stung. Venom immunotherapy (VIT) is highly effective in protecting individuals with ascertained Hymenoptera venom allergy (HVA) and previous severe reactions. After a 3- to 5-year VIT course, most patients remain protected after VIT discontinuation. Otherwise, a lifelong treatment should be considered in high-risk patients (eg, in mastocytosis). Several case reports evidenced that patients with mastocytosis and HVA, although protected during VIT, can re-experience severe and sometimes fatal reactions after VIT discontinuation...
December 16, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29250024/clinical-predictors-of-progressive-hemorrhagic-injury-in-children-with-mild-traumatic-brain-injury
#19
Guangfu Di, Hua Liu, Xiaochun Jiang, Yi Dai, Sansong Chen, Zhichun Wang, Hongyi Liu
Objective: Traumatic brain injury (TBI) occurs commonly in children. Repeat computed tomography (CT) follow up of TBI patients is often scheduled to identify progressive hemorrhagic injury (PHI). However, the utility of repeated CT scans, especially in children with mild TBI [Glasgow Coma Scale (GCS) scores of 13-15], has been debated. The purposes of the present study were to identify clinical predictors of PHI in children with mild TBI and to clarify relevant clinical factors via radiological examination...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29249173/long-term-prospective-memory-impairment-following-mild-traumatic-brain-injury-with-loss-of-consciousness-findings-from-the-canadian-longitudinal-study-on-aging
#20
Marc Bedard, Vanessa Taler, Jason Steffener
OBJECTIVE: We aimed to examine the extent to which loss of consciousness (LOC) following mild traumatic brain injury (mTBI) may be associated with impairments in time- and event-based prospective memory (PM). PM is thought to involve executive processes and be subserved by prefrontal regions. Neuroimaging research suggests alterations to these areas of the brain several years after mTBI, particularly if LOC was experienced. However, it remains unclear whether impairments in time- or event-based functioning may persist more than a year after mTBI, and what the link with duration of LOC may be...
December 18, 2017: Clinical Neuropsychologist
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