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autologous blood transfusion

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https://www.readbyqxmd.com/read/29422472/evaluation-of-hemoglobin-concentration-and-hematocrit-values-in-temporomandibular-joint-ankylosis-patients-in-comparison-to-nonankylosed-patients
#1
Deepinder Singh, Guneet Kaur, Dipanshu Bakshi, Jasjit Sahota, Ambika Thakur, Shekhar Grover
AIM: The aim of this study is to find if there is any correlation between the hematological parameters and temporomandibular joint (TMJ) ankylosis and severity of the disease in such patients when compared with the nonankylosed patients. MATERIALS AND METHODS: A total of 70 patients with age ranging from 10 to 40 years were included in the study after excluding the subjects according to the inclusion criteria. We categorized the subjects into two major groups: group I: control (nonankylosed/ healthy subjects) and group II: study group (ankylosed subjects) with each group containing 35 subjects (n = 35) respectively...
February 1, 2018: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29410296/low-cd34-cell-doses-are-associated-with-increased-cost-and-worse-outcome-following-of-tandem-autologous-stem-cell-transplantation-in-patients-with-relapsed-or-refractory-germ-cell-tumors
#2
Mustafa A Hyder, W Scott Goebel, Kirsten D Ervin, Jennifer E Schwartz, Michael J Robertson, Teresa C Thakrar, Costantine Albany, Sherif S Farag
Tandem autologous stem cell transplantation (ASCT) improves long-term survival of platinum-refractory germ cell tumors (GCT) patients. Studies, predominantly in lymphoma, showed that CD34+ cell doses > 5.0 x 106/kg/single transplant lead to decreased resource utilization. As most GCT patients have received prior cisplatin-based treatment, collecting >10x106 CD34+ cells/kg is challenging. We analyzed the effect of CD34+ cell dose on resource utilization and outcome of in 131 GCT patients, median age 29...
February 2, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29398813/a-study-of-preoperative-autologous-blood-donation-timing
#3
Jun Zhou, Zhen Chen, Jing Jin, Qiu-Li Zhang
This study aims to determine the safe and effective autologous blood drawing time for preoperative autologous blood donation (PABDs) by comparing the outcome of two different schedules of PABDs. A total of 144 patients who underwent elective surgery (radical resection of digestive tract tumor, lumbarspinesurgery and Intracranial tumor resection) were retrospectively reviewed. 88 patients had donated autologous blood 2 days before the operation (group 1); 56 patients had donated autologous blood more than 3 days before the operation (group 2)...
January 2018: Indian Journal of Hematology & Blood Transfusion
https://www.readbyqxmd.com/read/29378145/assessment-of-common-red-blood-cell-pretreatments-to-yield-an-accurate-serologic-antigen-phenotype-compared-with-genotypepredicted-phenotype
#4
Trina Horn, Janis Hamilton, Joanne Kosanke, Virginia W Hare, Wendy Kluver, Wendy Beres, Sandra Nance, Margaret A Keller
For patients requiring multiple transfusions and patients with positive direct antiglobulin tests (DATs), an extended red blood cell (RBC) phenotype can provide valuable information and help to determine the risk of forming alloantibodies. In some instances, the phenotype may be used for prophylactic matching. Phenotyping in this patient population is often hindered by the presence of circulating donor cells and/or by a positive DAT. Several methods, such as EDTA glycine acid (EGA) treatment to remove IgG, hypotonic saline wash to separate autologous RBCs, or reticulocyte separation, are often used in these situations to isolate patient RBCs for serologic phenotyping...
December 2017: Immunohematology
https://www.readbyqxmd.com/read/29296714/management-of-venous-thromboembolism-during-thrombocytopenia-after-autologous-hematopoietic-cell-transplantation
#5
Ang Li, Chris Davis, Qian Wu, Shan Li, Madeline F Kesten, Leona A Holmberg, Ajay K Gopal, David A Garcia
Management of venous thromboembolism (VTE) remains challenging in patients with hematologic malignancy who undergo hematopoietic cell transplantation (HCT) due to prolonged thrombocytopenia. This study aims to (1) determine the incidence of VTE recurrence and bleeding during autologous HCT, (2) assess the impact of continuing vs temporarily withholding anticoagulation during thrombocytopenia, and (3) explore the impact of platelet threshold among other variables on the risk of bleeding. We performed this observational study in adults with lymphoma and myeloma who underwent autologous HCT between 2006 and 2015...
May 9, 2017: Blood Advances
https://www.readbyqxmd.com/read/29284848/utility-of-acute-normovolemic-hemodilution-in-major-surgeries-in-rural-area-a-prospective-comparative-study-from-north-india
#6
Sujeet Rai, Satyajeet Verma, Pramod Kumar Yadav, Jawed Ahmad, Harikesh Kumar Yadav
Introduction: Easy availability of autologous blood is difficult in rural areas. Acute normovolemic hemodilution (ANH) has been found to be an effective alternative in major surgeries where we are expecting major blood loss. Patients and Methods: A prospective comparative study was designed to evaluate the utility of ANH patients (patients receiving autologous blood) during major operations done at MRA Medical College Ambedkar Nagar, Uttar Pradesh, India. during from September 2015 to September 2016...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29209789/-novel-aspects-of-the-guidelines-for-hemotherapy-2017-implications-for-anesthesiology
#7
REVIEW
I Pekrul, G Wittmann, P Möhnle
Based on the German Transfusion Law, the periodically updated guidelines "Richtlinien zur Gewinnung von Blut und Blutbestandteilen und zur Anwendung von Blutprodukten" ("Hämotherapierichtlinien") are intended to provide the current knowledge and state of the art of blood transfusion practice in Germany. The novel update 2017 contains relevant changes for blood donation, especially the extension of the exclusion period of persons at risk for sexually transmitted HBV, HCV and HIV diseases to 12 months. Moreover, the guidelines provide several changes relevant to blood transfusion practice in anesthesiology, such as: all autologous hemotherapy procedures including normovolemic hemodilution, cell saver, and autologous blood donation and transfusion require formal registration at the regulatory authority...
December 5, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/29193118/in-premature-infants-there-is-no-decrease-in-24-hour-posttransfusion-allogeneic-red-blood-cell-recovery-after-42-days-of-storage
#8
Demet Nalbant, José A Cancelas, Donald M Mock, Svetlana V Kyosseva, Robert L Schmidt, Gretchen A Cress, M Bridget Zimmerman, Ronald G Strauss, John A Widness
BACKGROUND: Critically ill preterm very-low-birthweight (VLBW) neonates (birthweight ≤ 1.5 kg) frequently develop anemia that is treated with red blood cell (RBC) transfusions. Although RBCs transfused to adults demonstrate progressive decreases in posttransfusion 24-hour RBC recovery (PTR24 ) during storage-to a mean of approximately 85% of the Food and Drug Administration-allowed 42-day storage-limited data in infants indicate no decrease in PTR24 with storage. STUDY DESIGN AND METHODS: We hypothesized that PTR24 of allogeneic RBCs transfused to anemic VLBW newborns: 1) will be greater than PTR24 of autologous RBCs transfused into healthy adults and 2) will not decrease with increasing storage duration...
November 29, 2017: Transfusion
https://www.readbyqxmd.com/read/29182137/is-autologous-blood-transfusion-cost-effective-in-adolescent-idiopathic-scoliosis
#9
I Sanpera, J Burgos-Flores, C Barrios, G Piza-Vallespir, L M Anton-Rodrigalvarez
The purpose of this study has been to evaluate the use of preoperative autologous blood donation (PABD) in the surgical treatment of adolescent idiopathic scoliosis (AIS). The surgical records of 37 AIS patients, Lenke type 1, were reviewed. Patients were classified according to whether they had entered the PABD (Program of Autologous Blood Donation) (25 patients) or had been rejected to join (12 patients non-donors). Both groups were comparable. All but one of the PADB patients (96%) as compared to only 2 non-donors patients (16...
December 2016: Acta Orthopaedica Belgica
https://www.readbyqxmd.com/read/29175805/review-autologous-blood-transfusion-drainage-compared-with-no-drainage-in-total-knee-arthroplasty-a-meta-analysis-and-systematic-review
#10
Kun-Hao Hong, Jian-Ke Pan, Hui Xie, Da Guo, Wei-Yi Yang, Hai-Tao Su, Shu-Chai Xu, Jun Liu
This is the first meta-analysis to assess the clinical efficiency, safety and potential advantages regarding the use of ABT drains compared with no drainage which is controversial in total knee arthroplasty (TKA).A comprehensive literature search was carried out in March 2015 using the PubMed, Embase, and Cochrane Library databases. A metaanalysis was carried out on two retrospective comparative studies (RCSs) and five randomized controlled trials (RCTs). The number of patients receiving homologous blood transfusion was the primary outcome of the meta-analysis; the secondary outcome measure was the mean drop in Hb level in comparison to the mean pre-operative HB level, the range of flexion of the knee joint, and infections of the wound after surgery...
November 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29130518/automated-red-blood-cell-exchange-in-preparation-for-filgrastim-mobilization-of-autologous-peripheral-blood-hematopoietic-progenitor-cells-in-a-patient-with-sickle-cell-anemia
#11
Yong Zhao, Jeffrey A Bailey, Jeanne Linden, Patricia St Pierre, Jan Cerny, Michelle Vauthrin, Mindy Greene, Robert Weinstein
Increasing survival of patients with sickle cell anemia (SCA) well into adulthood results in a rising likelihood of developing hematological malignancy. High-dose chemotherapy with autologous hematopoietic progenitor cell (HPC) rescue is standard of care for several hematological malignancies, but the risk of severe or life-threatening vaso-occlusive phenomena during filgrastim mobilization of HPC for collection poses a potential barrier to this approach. We report the use of automated red cell exchange in preparation for filgrastim mobilization in a patient with homozygous SCA...
November 11, 2017: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/29108378/preoperative-risk-factors-for-massive-blood-loss-in-adrenalectomy-for-pheochromocytoma
#12
Hongju Liu, Bin Li, Xuerong Yu, Yuguang Huang
Background: This retrospective analysis of patients who underwent adrenalectomy for pheochromocytoma aimed to determine preoperative risk factors for intraoperative massive blood loss. Preoperative identification of patients at high-risk of massive blood loss may be helpful in anesthesia management and preoperative preparation. Materials and Methods: The study involved data of 268 patients who had undergone pheochromocytoma surgery at the Peking Union Medical College Hospital between January 1, 2013 and October 31, 2016...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29107157/efficacy-reliability-and-safety-of-completely-autologous-fibrin-glue-in-neurosurgical-procedures-single-center-retrospective-large-number-case-study
#13
Noriyuki Nakayama, Hirohito Yano, Yusuke Egashira, Yukiko Enomoto, Naoyuki Ohe, Nobuhiro Kanemura, Junichi Kitagawa, Toru Iwama
OBJECTIVE: Commercially available fibrin glue (Com-FG) used commonly worldwide is produced with pooled human plasma from multiple donors and is added bovine aprotinin, however, which involves the risk of infection, allogenic immunity, and allergic reactions. We evaluate the efficacy, reliability, and safety of completely autologous fibrin glue (CAFG). METHODS: From August 2014 to February 2016, prospective data were collected and analyzed from 153 patients. CAFG was prepared with the CRYOSEAL(®) System using autologous blood and applied during neurosurgical procedures...
October 26, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29050721/acute-kidney-injury-secondary-to-cell-saver-in-posterior-spinal-fusion
#14
Anas A Minkara, Albert Y Lin, Michael G Vitale, David P Roye
BACKGROUND: Autologous blood transfusion, commonly referred to as cell saver, is frequently used in spinal fusion to salvage red blood cells because of the risk of significant intraoperative blood loss. This case report describes a case of acute kidney injury (AKI) secondary to cell saver use. Our objective is to increase the knowledge about the process of red blood cell salvage and this exceedingly rare complication. METHODS: Chart and renal biopsy results for a single case were reviewed and reported in this retrospective study...
November 2017: Spine Deformity
https://www.readbyqxmd.com/read/29045074/detection-of-autologous-blood-transfusions-using-a-novel-dried-blood-spot-method
#15
Holly D Cox, Geoffrey D Miller, Auriella Lai, Dan Cushman, Daniel Eichner
In doping control laboratories, autologous blood transfusions are currently detected using an indirect method that monitors changes in an athlete's hemoglobin concentration [Hb] and reticulocyte percent (Ret%) over time. The method is limited by the need for a phlebotomist to collect venous blood and the limited blood stability which requires temperature-controlled shipment and analysis within 72 hours. These limitations significantly reduce the number of samples collected from each athlete and thus the utility of the method...
October 16, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/29032269/second-hematopoietic-stem-cell-transplant-for-thalassemia-major-improved-clinical-outcomes-with-a-treosulfan-based-conditioning-regimen
#16
Anu Korula, Nisham Pn, Anup Devasia, Kavitha M Lakshmi, Aby Abraham, Eunice Sindhuvi, Biju George, Alok Srivastava, Vikram Mathews
Graft rejection (GR) after allogeneic stem cell transplantation (allo-SCT) occurs in 10% to 20% of patients with β-thalassemia major (TM). There are limited data on the clinical profile and long-term outcome of patients who have had a GR. We undertook a retrospective analysis of patients who had a graft failure after allo-SCT for TM at our center. From October 1991 to June 2016, 55 of 506 patients (11%) transplanted for TM had a graft failure. An additional 7 patients with graft failure after allo-SCT done at other centers were referred to us for a second transplant...
October 12, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29032158/location-affects-the-management-of-liver-haemangioma-a-retrospective-cohort-study
#17
Xiaolei Liu, Zhiying Yang, Haidong Tan, Li Xu, Liguo Liu, Jia Huang, Shuang Si, Yongliang Sun
BACKGROUND: The location of liver haemangioma may affect surgical decisions, but no study has ever examined this issue. METHODS: A retrospective study was performed on 338 liver haemangioma patients who visited at clinic. The collected data included demographics, location, symptoms and whether surgical treatment was performed. For patients with surgical treatment, the collected data included radiologic characteristics, surgical procedures, surgical variables, postoperative stay, morbidity, and mortality...
December 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29031409/a-study-of-the-pharmacokinetic-properties-and-the-in-vivo-kinetics-of-erythrocytes-loaded-with-dexamethasone-sodium-phosphate-in-healthy-volunteers
#18
REVIEW
Shodeinde A Coker, Zbigniew M Szczepiorkowski, Alan H Siegel, Antonio Ferrari, Giovanni Mambrini, Ravi Anand, Richard D Hartman, Luca Benatti, Larry J Dumont
The objectives of this 2-phase study were to elucidate pharmacokinetics (PK), in vivo 24-hour recovery, and red blood cell (RBC) survival properties of RBC-encapsulated dexamethasone sodium phosphate (DSP) prepared using the EryDex System (EDS). The 24-hour RBC recovery and T50 survival phase studied subjects were randomized to receive autologous RBCs loaded with either 15-20 mg DSP (Group 1A) or sham saline (Group 2A). Loaded RBCs were radiolabeled with 51-Cr, and the labeled RBCs were followed over time in vivo...
September 19, 2017: Transfusion Medicine Reviews
https://www.readbyqxmd.com/read/29018838/adverse-post-operative-outcomes-in-jehovah-s-witnesses-with-gynecologic-cancer-within-30%C3%A2-days-of-surgery-a-single-institution-review-of-36-cases
#19
Laura J Moulton, Peter G Rose, Haider Mahdi
Rates of blood transfusion are reported as high as 32% in women undergoing major gynecologic cancer surgery. Therefore, care of the gynecologic oncology patient who refuses blood products, such as Jehovah's witnesses, can pose a unique challenge. The objective of this study was to determine rate of adverse post-operative outcomes within 30 days of surgery in Jehovah's witnesses with gynecologic cancer. This was a retrospective cohort study of Jehovah's witnesses undergoing laparotomy or minimally invasive surgery (MIS) for gynecologic cancer at a single institution...
November 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28974399/perioperative-comparison-of-blood-loss-and-complications-between-simultaneous-bilateral-and-unilateral-total-knee-arthroplasty-for-knee-osteoarthritis
#20
Yongjian Qi, Kai Tie, Hua Wang, Zhengqi Pan, Xinyu Zhao, Heqiang Chen, Liaobin Chen
OBJECTIVE: This study aimed to compare the blood loss and complications between simultaneous bilateral total knee arthroplasty (SBTKA) and unilateral total knee arthroplasty (UTKA). METHODS: This study included 54 SBTKAs and 70 UTKAs performed between 2013 and 2014. Groups were compared with respect to blood loss, hemoglobin, hematocrit, D-dimer, blood transfusion, and complications. RESULTS: Hemoglobin between the groups was not significantly different (P>0...
September 30, 2017: Knee
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