Xuanhao Zhang, Jian Yang, Shixing Ma, Xin Gao, Guanyu Wang, Yanping Sun, Yejia Yu, Zhuo Wang, Weidong Tian, Li Liao
Apoptosis releases numerous apoptotic vesicles that regulate processes such as cell proliferation, immunity, and tissue regeneration and repair. Now, it has also emerged as an attractive candidate for biotherapeutics. However, apoptotic vesicles encompass a diverse range of subtypes, and it remains unclear which specific subtypes play a pivotal role. In this study, we successfully isolated different apoptotic vesicle subtypes based on their sizes and characterized them using NTA and TEM techniques, respectively...
April 2024: Journal of Extracellular Vesicles