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https://www.readbyqxmd.com/read/29332265/review-of-a-parent-s-influence-on-pediatric-procedural-distress-and-recovery
#1
REVIEW
Erin A Brown, Alexandra De Young, Roy Kimble, Justin Kenardy
Understanding how parents influence their child's medical procedures can inform future work to reduce pediatric procedural distress and improve recovery outcomes. Following a pediatric injury or illness diagnosis, the associated medical procedures can be potentially traumatic events that are often painful and distressing and can lead to the child experiencing long-term physical and psychological problems. Children under 6 years old are particularly at risk of illness or injury, yet their pain-related distress during medical procedures is often difficult to manage because of their young developmental level...
January 13, 2018: Clinical Child and Family Psychology Review
https://www.readbyqxmd.com/read/29332062/cytologic-features-of-malignant-melanoma-with-osteoclast-like-giant-cells
#2
José A Jiménez-Heffernan, Magdalena Adrados, Patricia Muñoz-Hernández, Paloma Fernández-Rico, Ana I Ballesteros-García, Javier Fraga
BACKGROUND: Malignant melanoma showing numerous osteoclast-like giant cells (OGCs) is an uncommon morphologic phenomenon, rarely mentioned in the cytologic literature. The few reported cases seem to have an aggressive clinical behavior. Although most findings support monocyte/macrophage differentiation, the exact nature of OGCs is not clear. CASE: A 57-year-old woman presented with an inguinal lymphadenopathy. Sixteen years before, cutaneous malignant melanoma of the lower limb had been excised...
January 13, 2018: Acta Cytologica
https://www.readbyqxmd.com/read/29332028/possible-erythrocyte-contributions-to-and-exacerbation-of-the-post-thrombolytic-no-reflow-phenomenon
#3
Shang-Jen Yu, James P Buerck, Edgar A O'Rear, Thomas L Whitsett
BACKGROUND: Reperfusion injury often occurs with therapeutic intervention addressing the arterial occlusions causing acute myocardial infarction and stroke. The no-reflow phenomenon has been ascribed to leukocyte plugging and blood vessel constriction in the microcirculation. OBJECTIVE: To assess possible red cell contributions to post thrombolytic no-reflow phenomenon. METHODS: Blood clots were formed by recalcifying 1 ml of citrated fresh human venous blood and then lysed by adding 1,000 units of streptokinase (SK) at several intervals within 1 hour...
January 11, 2018: Biorheology
https://www.readbyqxmd.com/read/29331792/candesartan-angiotensin-ii-type-1-receptor-blocker-is-able-to-relieve-age-related-cognitive-impairment
#4
Emil Trofimiuk, Przemysław Wielgat, Jan J Braszko
BACKGROUND: Candesartan is one of the standard antihypertensive drug belonging to AT1R angiotensin receptor blockers (ARBs) group. Beneficial effects of this drug in the treatment of hypertension are well recognized. In this study we tested a hypothesis that candesartan could alleviate age-related memory decline. METHODS: Aged and young rats have been treated with candesartan (0.1 mg kg-1) for 21 days and then underwent a battery of behavioral tests: for assessment of long-term memory (Passive avoidance test - PA), recognition memory (Object recognition test - OR), locomotor functions (Open field - OF) and anxiety behavior (Elevated plus maze - EPM)...
July 21, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29331602/a-cross-continental-analysis-of-weight-gain-psychiatric-diagnoses-and-medication-use-during-inpatient-psychiatric-treatment-the-international-study-on-physical-illness-in-mentally-ill
#5
Christina Engelke, Christian Lange-Asschenfeldt, Stephanie Peter, Kai G Kahl, Karel Frasch, Jens I Larsen, Graziella G Bickel, Bernhard Bork, Bent A Jacobsen, Signe O Wallenstein-Jensen, Christoph Lauber, Birthe Mogensen, Jørgen A Nielsen, Wulf Rössler, Kenji J Tsuchiya, Kristian L Toftegaard, Ulla A Andersen, Richard Uwakwe, Povl Munk-Jørgensen, Joachim Cordes
Weight gain among psychiatric inpatients is a widespread phenomenon. This change in body mass index (BMI) can be caused by several factors. Based on recent research, we assume the following factors are related to weight gain during psychiatric inpatient treatment: psychiatric medication, psychiatric diagnosis, sex, age, weight on admission and geographic region of treatment. 876 of originally recruited 2328 patients met the criteria for our analysis. Patients were recruited and examined in mental health care centres in Nigeria (N = 265), Japan (N = 145) and Western-Europe (Denmark, Germany and Switzerland; N = 466)...
December 22, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29331571/interdepartmental-imaging-protocol-for-clinically-based-three-dimensional-computed-tomography-can-provide-accurate-measurement-of-glenoid-version
#6
Connor L Zale, Gregory I Pace, Gregory S Lewis, John Chan, H Mike Kim
BACKGROUND: Conventional computed tomography (CT) is not accurate for glenoid version measurement. This study sought to examine the feasibility of an interdepartmental protocol implemented between orthopedic surgery and radiology departments for acquisition of anatomic axial CT images and to validate the glenoid version measured through such a protocol. MATERIALS AND METHODS: Data of 30 conventional CT scans of 10 normal and 20 osteoarthritic glenoids were transferred to clinical 3-dimensional imaging software by a radiology technician trained for the study...
January 10, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29331536/chronic-inflammation-and-sarcopenia-a-regenerative-cell-therapy-perspective
#7
Jagadish K Chhetri, Philipe de Souto Barreto, Bertrand Fougère, Yves Rolland, Bruno Vellas, Matteo Cesari
Sarcopenia is characterized by reduced skeletal muscle mass and strength in older individuals. It is one of the leading cause of physical limitation in older adults, and associated with wide spectrum of adverse events including disability and mortality. The phenomenon of chronic-inflammation or inflamm-aging with aging is known to be a major contributor to myriad of geriatric conditions including sarcopenia. Recent advances in regenerative medicine, in particular cell therapy have opened up new possibilities to ameliorate broad range of inflammatory disorders...
January 10, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29331309/what-is-the-predictive-value-of-st-segment-depression-in-inferior-leads-in-first-acute-anterior-myocardial-infarction
#8
Mert İlker Hayıroğlu, Muhammed Keskin, Ahmet Okan Uzun, Ceyhan Türkkan, Ahmet İlker Tekkeşin, Ömer Kozan
BACKGROUND: Electrical phenomenon and remote myocardial ischemia are the main factors of ST segment depression in inferior leads in acute anterior myocardial infarction (AAMI). We investigated the prognostic value of the sum of ST segment depression amplitudes in inferior leads in patients with first AAMI treated with primary percutaneous coronary intervention. (PPCI). METHODS: In this prospective analysis, we evaluated the in-hospital prognostic impact of the sum of ST segment depression in inferior leads on 206 patients with first AAMI...
December 12, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29331279/dynamics-of-spatiotemporal-distribution-of-schistosomiasis-in-hubei-province-china
#9
Yan-Yan Chen, Jian-Bing Liu, Yong Jiang, Guo Li, Xiao-Wei Shan, Juan Zhang, Shun-Xiang Cai, Xi-Bao Huang
Schistosomiasis caused by parasitic flatworms of blood flukes, remains a major public health concern in China. The significant progress in controlling schistosomiasis in China over the past decades has resulted in the remarkable reduction in the prevalence and intensity of Schistosoma japonicum infection to an extremely low level. Therefore, the elimination of schistosomiasis has been promoted by the Chinese national government. Hubei Province is the major endemic area, that is, along the middle and low reaches of the Yangtze River in the lake and marshland regions of southern China...
January 10, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29331203/have-we-forgotten-about-forgetting-a-critical-review-of-accelerated-long-term-forgetting-in-temporal-lobe-epilepsy
#10
REVIEW
Anneli Cassel, Michael D Kopelman
Forgetting has been researched for over a century. This literature highlighted how forgetting rates can vary dependent on factors in the design and method. Recent interest in forgetting revived with evidence suggesting that seizures experienced almost immediately after matched learning could accelerate forgetting. This was followed by a growth in forgetting studies in patients with temporal lobe epilepsy (TLE), including a subset of those with transient epileptic amnesia (TEA). These patients have been described as expressing concerns about memory, yet often perform within 'normal' ranges on standard neuropsychological memory assessments...
December 26, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29331145/modelling-the-effect-of-acoustic-waves-on-the-thermodynamics-and-kinetics-of-phase-transformation-in-a-solution-including-mass-transportation
#11
S R Haqshenas, I J Ford, N Saffari
Effects of acoustic waves on a phase transformation in a metastable phase were investigated in our previous work [S. R. Haqshenas, I. J. Ford, and N. Saffari, "Modelling the effect of acoustic waves on nucleation," J. Chem. Phys. 145, 024315 (2016)]. We developed a non-equimolar dividing surface cluster model and employed it to determine the thermodynamics and kinetics of crystallisation induced by an acoustic field in a mass-conserved system. In the present work, we developed a master equation based on a hybrid Szilard-Fokker-Planck model, which accounts for mass transportation due to acoustic waves...
January 14, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29330941/hydrophobic-and-hydrophilic-effects-on-water-structuring-and-adhesion-in-denture-adhesives
#12
Simrone K Gill, Nima Roohpour, Yiran An, Julien E Gautrot, Paul D Topham, Brian J Tighe
Denture adhesives are designed to be moisture-sensitive through the inclusion of a blend of polymer salts with varying degrees of water-sensitivity. This enables the adhesive to mix with saliva in vivo and activate its high tack, through the formation of a mucilaginous layer. We report for the first time, the use of differential scanning calorimetry (DSC) to study a series of hydrophobic and hydrophilic polymeric systems in order to correlate water-structuring behavior with adhesion strength. Adhesive bonding of the more hydrophobic variants was higher than that of a commercial-based control and a more hydrophilic polymer system in both lap shear and tensile configurations...
January 13, 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29330852/characteristics-and-intestinal-immunomodulating-activities-of-water-soluble-pectic-polysaccharides-from-chenpi-with-different-storage-periods
#13
Changcheng Tian, Xu Hui, Jing Li, Zhuo Han
BACKGROUND: Traditional view considers that the long-term stored Chenpi (dried citrus peel) has better health efficacies as compared with the fresh Chenpi, but the detailed mechanism remains obscure. RESULTS: The three water-soluble pectic polysaccharides (CPP1, CPP5 and CPP10) were obtained from one-year, five-year and ten-year Chenpi, respectively, and their physicochemical characteristics and intestinal immunomodulating activities were investigated and compared...
January 13, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29330710/glycogen-production-in-marine-cyanobacterial-strain-synechococcus-sp-nkbg-15041c
#14
Amr Badary, Shouhei Takamatsu, Mitsuharu Nakajima, Stefano Ferri, Peter Lindblad, Koji Sode
An important feature offered by marine cyanobacterial strains over freshwater strains is the capacity to grow in seawater, replacing the need for often-limited freshwater. However, there are only limited numbers of marine cyanobacteria that are available for genetic manipulation and bioprocess applications. The marine unicellular cyanobacteria Synechococcus sp. strain NKBG 15041c (NKBG15041c) has been extensively studied. Recombinant DNA technologies are available for this strain, and its genomic information has been elucidated...
January 12, 2018: Marine Biotechnology
https://www.readbyqxmd.com/read/29330445/a-novel-approach-for-correction-of-crosstalk-effects-in-pathway-analysis-and-its-application-in-osteoporosis-research
#15
Yu Zhou, Yunlong Gao, Chao Xu, Hui Shen, Qing Tian, Hong-Wen Deng
Osteoporosis is a prevalent bone metabolic disease and peripheral blood monocytes represent a major systemic cell type for bone metabolism. To identify the key dysfunctional pathways in osteoporosis, we performed pathway analyses on microarray data of monocytes from subjects with extremely high/low hip bone mineral density. We first performed a traditional pathway analysis for which different pathways were treated as independent. However, genes overlap among pathways will lead to "crosstalk" phenomenon, which may lead to false positive/negative results...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29330359/strong-grain-neighbour-effects-in-polycrystals
#16
Hamidreza Abdolvand, Jonathan Wright, Angus J Wilkinson
Anisotropy in single-crystal properties of polycrystals controls both the overall response of the aggregates and patterning of local stress/strain distributions, the extremes of which govern failure processes. Improving the understanding of grain-grain interactions has important consequences for in-service performance limits. Three-dimensional synchrotron X-ray diffraction was used to study the evolution of grain-resolved stresses over many contiguous grains in Zr and Ti polycrystals deformed in situ. In a significant fraction of grains, the stress along the loading axis was found to decrease during tensile plastic flow just beyond the macroscopic yield point; this is in the absence of deformation twinning and is a surprising behaviour...
January 12, 2018: Nature Communications
https://www.readbyqxmd.com/read/29330036/regulation-of-fibrotic-changes-by-the-synergistic-effects-of-cytokines-dimensionality-and-matrix-towards-the-development-of-an-in-vitro-human-dermal-hypertrophic-scar-model
#17
Shikha Chawla, Sourabh Ghosh
Current therapeutic strategies to reduce scarring in full thickness skin defect offer limited success due to poor understanding of scar tissue formation and the underlying signaling pathways. There is an urgent need to develop human cell based in vitro scar tissue models as animal testing is associated with ethical and logistic complications and inter-species variations. Pro-inflammatory cytokines play critical role in regulating scar development through complex interplay and interaction with the ECM and corresponding signaling pathways...
January 9, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29330026/sound-shock-response-in-larval-zebrafish-a-convenient-and-high-throughput-assessment-of-auditory-function
#18
Xiuyun Liu, Jia Lin, Yinglan Zhang, Ning Guo, Qiang Li
Given that hearing ability can be challenged in diverse ways, it is necessary to develop an easily conducted, high-throughput method for assessing potential auditory risks. Measuring the acoustic startle response (ASR) has become a critical behavioral method in hearing research using zebrafish (Danio rerio). In this study, changes in the activity of zebrafish larvae (10 days post fertilization (dpf)) due to exposure to a sudden easily-generated broad-band noise were automatically and objectively recorded and analyzed without building sophisticated equipments...
January 9, 2018: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/29329232/novel-6-and-7-substituted-coumarins-with-inhibitory-action-against-lipoxygenase-and-tumor-associated-carbonic-anhydrase-ix
#19
Aikaterini Peperidou, Silvia Bua, Murat Bozdag, Dimitra Hadjipavlou-Litina, Claudiu T Supuran
A series of carboxamide derivatives of 6- and 7-substituted coumarins have been prepared by an original procedure starting from the corresponding 6- or 7-hydroxycoumarins which were alkylated with ethyl iodoacetate, and the obtained ester was converted to the corresponding carboxylic acids which were thereafter reacted with a series of aromatic/aliphatic/heterocyclic amines leading to the desired amides. The new derivatives were investigated as inhibitors of two enzymes, human carbonic anhydrases (hCAs) and soy bean lipoxygenase (LOX)...
January 12, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29329173/continuous-positive-airway-pressure-thresholds-for-nasolacrimal-air-regurgitation-in-a-cadaveric-model
#20
Alexander D Blandford, Daniel G Cherfan, Richard L Drake, Jennifer M McBride, Catherine J Hwang, Julian D Perry, Olivia T Cheng
PURPOSE: To elucidate the mechanisms underlying nasolacrimal air regurgitation (AR) in the setting of continuous positive airway pressure therapy. METHODS: Twelve nasolacrimal systems of 6 fresh female human cadavers were evaluated individually for AR using continuous positive airway pressure therapy before any nasolacrimal procedure. Cadavers were then randomly assigned to undergo nasolacrimal duct probing or endoscopic dacryocystorhinostomy and then each hemisystem was again evaluated for AR...
January 10, 2018: Ophthalmic Plastic and Reconstructive Surgery
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