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https://www.readbyqxmd.com/read/28434261/strategies-to-prevent-infections-associated-with-cardiovascular-implantable-electronic-devices
#1
Bharath Raj Palraj, Saira Farid, M Rizwan Sohail
Infections involving cardiovascular implantable electronic devices (CIED) are associated with high morbidity and mortality and substantial financial cost. In the past two decades, the rate of CIED infections has increased disproportionate to the number of devices implanted, likely due to aging patient population with multiple comorbidities. Microbial contamination of the generator pocket and or leads by skin flora at the time of implantation is a major mechanism for early CIED infections. Due to resistance to host immune cells and antibiotics caused by biofilm formation, complete removal of the device generator and leads is required to achieve cure...
April 24, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28430010/prolonged-injectable-formulation-of-nafarelin-using-in-situ-gel-combination-delivery-system
#2
Behnoush Alizadeh, Nika Bahari Javan, Hamid Akbari Javar, Mohammad Reza Khoshayand, Farid Abedin Dorkoosh
The principal purpose of the present study was to prepare and characterize a complex drug delivery system consisting of Nafarelin- poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) nanoparticles (NPs) in combination with sodium alginate/poloxamer 407 in situ gel. Nafarelin loaded PHBV NPs were prepared via double emulsion solvent evaporation technique. Box-Behnken Response Surface Methodology was utilized to optimize NPs. Mean particle size, polydispersity index (PDI), entrapment efficiency (EE) and drug loading (DL) of the optimized NPs were measured...
April 21, 2017: Pharmaceutical Development and Technology
https://www.readbyqxmd.com/read/28429687/postural-orthostatic-tachycardia-a-syndrome-requiring-detailed-search-for-associated-conditions
#3
EDITORIAL
Farid Aliyev
No abstract text is available yet for this article.
April 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28427082/perioperative-outcomes-and-safety-of-atrial-fibrillation-catheter-ablation-in-octogenarians-a-retrospective-study-and-review-of-the-benefits-of-rhythm-control
#4
Stephanie Hakimian, Juan C Camacho, Edwin Grajeda Silvestri, Farid AbdelMalak, Elie Donath, Robert Chait
OBJECTIVES: Catheter ablation for rhythm control has emerged as a successful therapeutic option for the treatment of atrial fibrillation (AF), though it has not been well studied in octogenarians. This study evaluates its safety in octogenarians in a community hospital and reviews the benefits of rhythm control. METHODS: Among 1,592 patients undergoing AF ablation, 84 octogenarian were identified. The primary outcome was normal sinus rhythm (NSR) on electrocardiogram at discharge...
April 21, 2017: Cardiology
https://www.readbyqxmd.com/read/28421834/long-term-testosterone-therapy-improves-cardiometabolic-function-and-reduces-risk-of-cardiovascular-disease-in-men-with-hypogonadism
#5
Abdulmaged M Traish, Ahmad Haider, Karim Sultan Haider, Gheorghe Doros, Farid Saad
OBJECTIVES: In the absence of large, prospective, placebo-controlled studies of longer duration, substantial evidence regarding the safety and risk of testosterone (T) therapy (TTh) with regard to cardiovascular (CV) outcomes can only be gleaned from observational studies. To date, there are limited studies comparing the effects of long-term TTh in men with hypogonadism who were treated or remained untreated with T, for obvious reasons. We have established a registry to assess the long-term effectiveness and safety of T in men in a urological setting...
January 1, 2017: Journal of Cardiovascular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28421149/eccrine-nevus-presenting-with-umbilical-discharge-a-case-report-and-review-of-the-literature
#6
Farahnaz Bidari-Zerehpoosh, Shahram Sabeti, Farid Arman, Hania Shakeri
Eccrine nevus is a rare skin lesion with protean manifestations like hyperhidrosis, discolored nodules, papules, and so forth, which has been reported in various anatomic parts of the body including the forearm, leg, thigh, back, and coccyx. Our patient was a 26-year-old male, who presented with increasing colorless and odorless episodic umbilical discharge. First impression for the patient was an umbilical sinus and the patient underwent surgery. Histopathological study revealed the lesion to be an eccrine nevus of the umbilicus...
2017: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/28416600/induction-of-an-ifn-mediated-antiviral-response-by-a-self-amplifying-rna-vaccine-implications-for-vaccine-design
#7
Timothy Pepini, Anne-Marie Pulichino, Thomas Carsillo, Alicia L Carlson, Farid Sari-Sarraf, Katrin Ramsauer, Jason C Debasitis, Giulietta Maruggi, Gillis R Otten, Andrew J Geall, Dong Yu, Jeffrey B Ulmer, Carlo Iavarone
RNA-based vaccines have recently emerged as a promising alternative to the use of DNA-based and viral vector vaccines, in part because of the potential to simplify how vaccines are made and facilitate a rapid response to newly emerging infections. SAM vaccines are based on engineered self-amplifying mRNA (SAM) replicons encoding an Ag, and formulated with a synthetic delivery system, and they induce broad-based immune responses in preclinical animal models. In our study, in vivo imaging shows that after the immunization, SAM Ag expression has an initial gradual increase...
April 17, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28414590/reduction-in-cd16-cd56-and-cd16-cd3-cd56-natural-killer-cells-in-coronary-artery-disease
#8
Nasimudeen R Jabir, Chelapram K Firoz, Farid Ahmed, Mohammad A Kamal, Salwa Hindawi, Ghazi A Damanhouri, Hussein A Almehdar, Shams Tabrez
BACKGROUND: Natural killer (NK) cells are the potential modulators of inflammatory reactions that exert several unique biological effects and could lead to future adverse events of coronary artery disease (CAD). HYPOTHESIS: The purpose of this study was to find out the possible association of modulation in NK cell, TNK cells, T cells, B cells, and tumor necrosis factor alpha (TNF-α) in CAD patients and various forms of myocardial infarction. METHODS: The present study included total 190 subjects (98 confirmed CAD patients both men and women and 92 healthy control individuals)...
April 17, 2017: Immunological Investigations
https://www.readbyqxmd.com/read/28411259/cerebral-embolic-protection-devices-during-transcatheter-aortic-valve-implantation-systematic-review-and-meta-analysis
#9
Rodrigo Bagur, Karla Solo, Saleh Alghofaili, Luis Nombela-Franco, Chun Shing Kwok, Samual Hayman, Reed A Siemieniuk, Farid Foroutan, Frederick A Spencer, Per O Vandvik, Tim G Schäufele, Mamas A Mamas
BACKGROUND AND PURPOSE: Silent ischemic embolic lesions are common after transcatheter aortic valve implantation (TAVI). The use of embolic protection devices (EPD) may reduce the occurrence of these embolic lesions. Thus, a quantitative overview and credibility assessment of the literature was necessary to draw a robust message about EPD. Therefore, the aim of this meta-analysis was to study whether the use of EPD reduces silent ischemic and clinically evident cerebrovascular events associated with TAVI...
April 14, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28410726/surgical-techniques-and-adjuvants-for-the-management-of-primary-and-recurrent-pterygia
#10
REVIEW
John A Hovanesian, Christopher E Starr, David T Vroman, Francis S Mah, Jose A P Gomes, Marjan Farid, Neda Shamie, Richard S Davidson, Thomas John, Edward J Holland, Terry Kim
The removal and rate of recurrence of pterygium have been discussed for years. The disorder is highly associated with environmental factors, and recurrence rates can be unacceptably high and cannot be successfully predicted. New techniques and graft preparations and postoperative management strategies are helping to reduce the recurrence rates and provide an ocular surface that is near ideal for future cataract or refractive surgery. This review discusses the advantages and disadvantages of various treatment strategies...
March 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28408266/analysis-of-clinical-results-of-three-different-routes-of-percutaneous-endoscopic-transforaminal-lumbar-discectomy-for-lumbar-herniated-disk
#11
Hyeun Sung Kim, Farid Yudoyono, Byapak Paudel, Jee Soo Jang, Jeong Hoon Choi, Sung Kyun Chung, Jeong Hoon Kim, Il Tae Jang, Seong Hoon Oh, Jae Eun Park, Sol Lee
OBJECTIVE: Percutaneous endoscopic transforaminal lumbar discectomy (PETLD) can be performed by using foraminal, intervertebral and suprapedicular routes. The aim of this study was to assess clinical results of three different routes of percutaneous endoscopic transforaminal lumbar discectomy (PETLD). METHODS: 111 patients who had undergone PETLD between January 2016 and October 2016 were included in this study. PETLD was performed by using the foraminal (group A), intervertebral (group B), and suprapedicular (group C) routes in 32, 46, and 33 patients, respectively...
April 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28400825/association-of-anatomic-variations-with-antrochoanal-polyps-in-paranasal-sinus-computed-tomography-scan
#12
Ali Hekmatnia, Farid Shirvani, Farhad Mahmoodi, Mostafa Hashemi
BACKGROUND: This study was designed to determine the prevalence of concomitant anatomic variation of paranasal sinuses in patients with antrochoanal polyp (ACP). MATERIALS AND METHODS: Among patients referred by their clinicians for standard computed tomography scan of paranasal sinuses septal deviation, concha bullosa, and retention cyst were evaluated in both patients with ACP as well as in a control group. RESULTS: Of the 17 patients with ACP, fifteen patients (88...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28393056/report-of-common-aeroallergens-among-allergic-patients-in-northeastern-iran
#13
Yaghoub Mahboubi Oskouei, Reza Farid Hosseini, Hamid Ahanchian, Lida Jarahi, Nazila Ariaee, Farahzad Jabbari Azad
INTRODUCTION: The prevalence of atopic diseases has increased in recent decades dramatically. The most common aeroallergens in Northeastern Iran have not been fully defined. Determining the most common aeroallergens in allergic patients based on the skin prick test (SPT) was aimed in this investigation. MATERIALS AND METHODS: This cross-sectional study enrolled 1,006 allergic patients (aged 1-86 years) from October 2010 to February 2014 referred to the Allergy clinics of Mashhad University of Medical Science...
March 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28392963/treatment-with-rutin-a-therapeutic-strategy-for-neutrophil-mediated-inflammatory-and-autoimmune-diseases-anti-inflammatory-effects-of-rutin-on-neutrophils
#14
Bahareh Abd Nikfarjam, Mohtaram Adineh, Farid Hajiali, Marjan Nassiri-Asl
OBJECTIVES: Neutrophils represent the front line of human defense against infections. Immediately after stimulation, neutrophilic enzymes are activated and produce toxic mediators such as pro-inflammatory cytokines, nitric oxide (NO) and myeloperoxidase (MPO). These mediators can be toxic not only to infectious agents but also to host tissues. Because flavonoids exhibit antioxidant and anti-inflammatory effects, they are subjects of interest for pharmacological modulation of inflammation...
March 2017: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28392819/computer-based-technologies-in-dentistry-types-and-applications
#15
REVIEW
Raja'a M Albuha Al-Mussawi, Farzaneh Farid
During dental education, dental students learn how to examine patients, make diagnosis, plan treatment and perform dental procedures perfectly and efficiently. However, progresses in computer-based technologies including virtual reality (VR) simulators, augmented reality (AR) and computer aided design/computer aided manufacturing (CAD/CAM) systems have resulted in new modalities for instruction and practice of dentistry. Virtual reality dental simulators enable repeated, objective and assessable practice in various controlled situations...
June 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28391758/the-frequency-of-hbb-mutations-among-%C3%AE-thalassemia-patients-in-hamadan-province-iran
#16
Masoumeh Jalilian, Farid Azizi Jalilian, Leila Ahmadi, Razieh Amini, Hossein Esfehani, Maryam Sosanian, Bahareh Rabbani, Majid Maleki, Nejat Mahdieh
β-Thalassemia (β-thal) caused by mutations on the HBB gene is the most common single-gene disorder in the world. In this study, the HBB gene mutation was investigated in Hamadan province, Iran. Forty-one patients referred to a referral hospital were admitted to the study. DNA samples were extracted from peripheral blood. The HBB gene was sequenced in all recruited patients. Eleven mutations and eight polymorphisms were found in the studied patients. IVS-II-1 (G>A) (HBB: c.315+1 G>A) was the most common mutation, accounting for 25...
April 10, 2017: Hemoglobin
https://www.readbyqxmd.com/read/28390587/clinical-features-of-adolescents-with-chronic-idiopathic-or-spontaneous-urticaria-review-of-omalizumab-clinical-trials
#17
Stanley Goldstein, Susan Gabriel, Farid Kianifard, Benjamin Ortiz, David P Skoner
BACKGROUND: Adults and adolescents were included in 3 phase 3 omalizumab trials in chronic idiopathic urticaria (CIU): ASTERIA I, ASTERIA II, and GLACIAL. OBJECTIVE: To describe the baseline clinical profile of adolescent patients with CIU enrolled in the omalizumab trials to add to the limited literature available on CIU in this population. METHODS: Data for patient demographics, baseline clinical disease characteristics, medical history, and previous CIU medication information (not efficacy assessments) from phase 3 omalizumab trials were pooled and descriptive statistical analyses performed for adolescent (12 to <18 years old) and adult (≥18 years old) subgroups...
April 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28389917/a-green-analytical-chemistry-approach-for-lipid-extraction-computation-methods-in-the-selection-of-green-solvents-as-alternative-to-hexane
#18
Mari Merce Cascant, Cassandra Breil, Salvador Garrigues, Miguel de la Guardia, Anne Silvie Fabiano-Tixier, Farid Chemat
There is a great interest in finding alternatives and green solvents in extraction processes to replace petroleum based solvents. In order to investigate these possibilities, computational methods, as Hansen solubility parameters (HSP) and conductor-like screening model for real solvent (COSMO-RS), were used in this work to predict the solvation power of a series of solvents in salmon fish lipids. Additionally, experimental studies were used to evaluate the performance in lipids extraction using 2-methyltetrahydrofurane, cyclopentyl methyl ether, dimethyl carbonate, isopropanol, ethanol, ethyl acetate, p-cymene and d-limonene compared with hexane...
April 7, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28388455/poverty-low-education-and-the-expression-of-psychotic-like-experiences-in-the-general-population-of-s%C3%A3-o-paulo-brazil
#19
Alexandre Andrade Loch, Camille Chianca, Tania Maria Alves, Elder Lanzani Freitas, Lucas Hortêncio, Julio Cesar Andrade, Martinus Theodorus van de Bilt, Marcos Roberto Fontoni, Mauricio H Serpa, Wagner Farid Gattaz, Wulf Rössler
The aim of our study was to assess psychotic-like experiences in the general population aged 18-30 years old of the city of São Paulo, Brazil. A household survey was conducted with 1950 young-adults randomly drawn from the city's general population. The validated 92-item Portuguese version of the Prodromal Questionnaire (PQ) was used for face-to-face interviews. Latent class analysis was conducted. Mean age was of 24 years; 51.1% of the sample was of women. Mean total score on the PQ was 22.06 (SD=17.16). Considering a suggested cut-off of 14 in the positive subscale, 30...
March 31, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28387947/diagnostic-tools-in-ocular-allergy
#20
Andrea Leonardi, Serge Doan, Jean Luc Fauquert, Banu Bozkurt, Pia Allegri, Farid Marmouz, Carmen Rondon, Monica Jedrzejczak, Peter Hellings, Luis Delgado, Virginia Calder
Ocular allergy (OA) includes a group of common and less frequent hypersensitivity disorders frequently misdiagnosed and not properly managed. The diagnosis of OA is usually based on clinical history and signs and symptoms, with the support of in vivo and in vitro tests when identification of the specific allergen is required. To date, no specific test is available for the diagnosis of the whole spectrum of the different forms of OA. The lack of recommendations on diagnosis of OA is considered a medical need not only for allergists but also for ophthalmologists...
April 7, 2017: Allergy
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