Chase A Knibbe, Rakib Uddin Ahmed, Felicia Wilkins, Mayur Sharma, Jay Ethridge, Monique Morgan, Destiny Gibson, Kimberly B Cooper, Dena R Howland, Manicka V Vadhanam, Shirish S Barve, Steven Davison, Leslie C Sherwood, Jack Semler, Thomas Abell, Maxwell Boakye
Gastrointestinal (GI) complications, including motility disorders, metabolic deficiencies, and changes in gut microbiota following spinal cord injury (SCI), are associated with poor outcomes. After SCI, the autonomic nervous system becomes unbalanced below the level of injury and can lead to severe GI dysfunction. The SmartPill™ is a non-invasive capsule that, when ingested, transmits pH, temperature, and pressure readings that can be used to assess effects in GI function post-injury. Our minipig model allows us to assess these post-injury changes to optimize interventions and ultimately improve GI function...
June 7, 2023: Biomedicines