keyword
MENU ▼
Read by QxMD icon Read
search

Minor tBI

keyword
https://www.readbyqxmd.com/read/27901414/cognitive-deficits-and-inflammatory-response-resulting-from-mild-to-moderate-traumatic-brain-injury-in-rats-are-exacerbated-by-repeated-pre-exposure-to-an-innate-stress-stimulus
#1
Michaël Ogier, Amor Belmeguenai, Thomas Lieutaud, Béatrice Georges, Sandrine Bouvard, Emilie Carré, Frédéric Canini, Laurent Bezin
Traumatic brain injury (TBI) is common in both military and civilian populations, and often results in neurobehavioral sequelae that impair quality of life in both patients and their family. Although individuals who are chronically exposed to stress are more likely to experience TBI, it is still unknown whether pre-injury stress influences the outcome after TBI. The present study tested whether behavioral and cognitive long-term outcome after TBI in rats is affected by prior exposure to an innate stress stimulus...
November 30, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27862642/external-validation-of-the-pecarn-head-trauma-prediction-rules-in-japan
#2
Kentaro Ide, Satoko Uematsu, Kenichi Tetsuhara, Satoshi Yoshimura, Takahiro Kato, Tohru Kobayashi
OBJECTIVES: The Pediatric Emergency Care Applied Research Network (PECARN) head trauma prediction rules are used to assist computed tomography (CT) decision-making for children with minor head trauma. Although the PECARN rules have been validated in North America and Europe, they have not yet been validated in Asia. In Japan, there are no clinical decision rules for children with minor head trauma. The rate of head CT for children with minor head trauma in Japan is high since CT is widely accessible across the country...
November 12, 2016: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/27834535/a-retrospective-cohort-study-of-comorbidity-trajectories-associated-with-traumatic-brain-injury-in-veterans-of-the-iraq-and-afghanistan-wars
#3
Mary Jo Pugh, Erin P Finley, Chen-Pin Wang, Laurel A Copeland, Carlos A Jaramillo, Alicia A Swan, Christine A Elnitsky, Luci K Leykum, Eric M Mortensen, Blessen A Eapen, Polly H Noel, Jacqueline A Pugh
OBJECTIVES: To identify and validate trajectories of comorbidity associated with traumatic brain injury in male and female Iraq and Afghanistan war Veterans (IAV). METHODS: Derivation and validation cohorts were compiled of IAV who entered the Department of Veterans Affairs (VA) care and received 3 years of VA care between 2002-2011. Chronic disease and comorbidities associated with deployment including TBI were identified using diagnosis codes. A latent class analysis (LCA) of longitudinal comorbidity data was used to identify trajectories of comorbidity...
2016: Brain Injury: [BI]
https://www.readbyqxmd.com/read/27775489/head-injury-screening-and-intimate-partner-violence-a-brief-report
#4
Kerry L Gagnon, Anne P DePrince
OBJECTIVE: While the importance of traumatic brain injury (TBI) has gained public attention in recent years, relatively little attention has been paid to head injuries among women who have experienced intimate partner violence (IPV). The present study screened for lifetime exposure to mild traumatic brain injuries (mTBI) among a sample of women who experienced recent IPV (median days since target incident = 26). METHOD: Participants included ethnically diverse women whose IPV experiences were reported to law enforcement...
October 24, 2016: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/27764546/the-psychological-impact-of-traffic-injuries-sustained-in-a-road-crash-by-bicyclists-a-prospective-study
#5
A Craig, N A Elbers, J Jagnoor, B Gopinath, A Kifley, M Dinh, I Pozzato, R Q Ivers, M Nicholas, I D Cameron
OBJECTIVE: To investigate the psychological impact of traffic injuries in bicyclists (cyclists) with comparisons to car occupants who also have sustained traffic injuries. Factors predictive of elevated psychological distress were also investigated. METHODS: An inception cohort prospective design was used. Participants included cyclists who sustained a physical injury (n = 238) aged ≥17 years (mean age 41.7yrs), assessed within 28 days of the crash, following medical examination by a registered healthcare practitioner...
October 20, 2016: Traffic Injury Prevention
https://www.readbyqxmd.com/read/27741077/acute-outcomes-of-isolated-pneumocephali-in-children-after-minor-blunt-head-trauma
#6
Ashley Blanchard, Keven I Cabrera, Nathan Kuppermann, Peter S Dayan
OBJECTIVES: We aimed to determine the prevalence of and adverse outcomes caused by pneumocephali in children with minor blunt head trauma who had no other intracranial injuries (ie, isolated pneumocephali). METHODS: We conducted a secondary analysis of a public use dataset from a multicenter prospective study of pediatric minor head trauma. We included children younger than 18 years with Glasgow Coma Scale (GCS) scores of 14 or 15 and non-trivial mechanisms of injury who had cranial computed tomographies obtained...
October 6, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27677908/abcc8-single-nucleotide-polymorphisms-are-associated-with-cerebral-edema-in-severe-tbi
#7
Ruchira M Jha, Ava M Puccio, David O Okonkwo, Benjamin E Zusman, Seo-Young Park, Jessica Wallisch, Philip E Empey, Lori A Shutter, Robert S B Clark, Patrick M Kochanek, Yvette P Conley
OBJECTIVE: Cerebral edema (CE) in traumatic brain injury (TBI) is the consequence of multiple underlying mechanisms and is associated with unfavorable outcomes. Genetic variability in these pathways likely explains some of the clinical heterogeneity observed in edema development. A role for sulfonylurea receptor-1 (Sur1) in CE is supported. However, there are no prior studies examining the effect of genetic variability in the Sur1 gene (ABCC8) on the development of CE. We hypothesize that ABCC8 single nucleotide polymorphisms (SNPs) are predictive of CE...
September 27, 2016: Neurocritical Care
https://www.readbyqxmd.com/read/27637440/the-effect-of-prehospital-intubation-on-treatment-times-in-patients-with-suspected-traumatic-brain-injury
#8
Joshua D Lansom, Kate Curtis, Helen Goldsmith, Alex Tzannes
OBJECTIVE: This study examines whether, in patients requiring intubation with moderate to severe traumatic brain injury (TBI), prehospital intubation compared with emergency department intubation leads to a reduction in treatment times and time to a computed tomographic (CT) scan. METHODS: A retrospective cohort study compared adult patients with a Glasgow Coma Score of less than 14 with a suspected TBI who underwent intubation, either prehospital or on arrival to the emergency department...
September 2016: Air Medical Journal
https://www.readbyqxmd.com/read/27322378/equestrian-related-traumatic-brain-injury-in-the-pediatric-population
#9
Ha Son Nguyen, Sean Lew
BACKGROUND: Equestrian activities can be undertaken for competition or leisure. Accidents can lead to bodily injuries. In particular, traumatic brain injury (TBI) can be devastating. Limited data exist regarding the pediatric population with respect to patterns of injury and related neurosurgical intervention. METHODS: We retrospectively reviewed data for all pediatric patients diagnosed with equestrian-related injuries with neurological injuries from 2005 through June 2015...
2016: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27251119/catecholamines-and-paroxysmal-sympathetic-hyperactivity-after-traumatic-brain-injury
#10
Juan F Fernandez-Ortega, Ian J Baguley, Thomas A Gates, Manuel Garcia-Caballero, Juan G Quesada-Garcia, Miguel A Prieto-Palomino
Paroxysmal sympathetic hyperactivity (PSH) affects a significant minority of people in the intensive care unit after severe traumatic brain injury. Systematic research has yet to elucidate or quantify the extent of the role of the catecholamines or adrenocortical and thyroid axis hormonal influences in the condition. Data were prospectively collected on 80 consecutive patients, 18 of whom developed clinical signs of PSH (22.5%). Catecholamine and hormonal data were collected sequentially at 4-h intervals or during and between episodes of PSH...
July 8, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27243415/variation-in-anticonvulsant-selection-and-electroencephalographic-monitoring-following-severe-traumatic-brain-injury-in-children-understanding-resource-availability-in-sites-participating-in-a-comparative-effectiveness-study
#11
Jonathan E Kurz, Samuel M Poloyac, Nicholas S Abend, Anthony Fabio, Michael J Bell, Mark S Wainwright
OBJECTIVES: Early posttraumatic seizures may contribute to worsened outcomes after traumatic brain injury. Evidence to guide the evaluation and management of early posttraumatic seizures in children is limited. We undertook a survey of current practices of continuous electroencephalographic monitoring, seizure prophylaxis, and the management of early posttraumatic seizures to provide essential information for trial design and the development of posttraumatic seizure management pathways...
July 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27224640/transcranial-doppler-to-predict-neurologic-outcome-after-mild-to-moderate-traumatic-brain-injury
#12
Pierre Bouzat, Luc Almeras, Pauline Manhes, Laurence Sanders, Albrice Levrat, Jean-Stephane David, Raphael Cinotti, Russel Chabanne, Aurélie Gloaguen, Xavier Bobbia, Sophie Thoret, Lydia Oujamaa, Jean-Luc Bosson, Jean-François Payen, Karim Asehnoune, Philippe Pes, Jean-Yves Lefrant, Sébastien Mirek, François Albasini, Caron Scrimgeour, Jean-Marc Thouret, Freddy Chartier, Marc Ginet
BACKGROUND: To assess the performance of transcranial Doppler (TCD) in predicting neurologic worsening after mild to moderate traumatic brain injury. METHODS: The authors conducted a prospective observational study across 17 sites. TCD was performed upon admission in 356 patients (Glasgow Coma Score [GCS], 9 to 15) with mild lesions on cerebral computed tomography scan. Normal TCD was defined as a pulsatility index of less than 1.25 and diastolic blood flow velocity higher than 25 cm/s in the two middle cerebral arteries...
August 2016: Anesthesiology
https://www.readbyqxmd.com/read/27215444/trauma-specific-brain-abnormalities-in-suspected-mild-tbi-patients-identified-in-the-first-48-hours-after-injury-a-blinded-mri-comparative-study-including-suspected-acute-minor-stroke-patients
#13
Maria Chiara Ricciardi, Reinoud Bokkers, John Butman, Dima Hammoud, Dzung L Pham, Steven Warach, Lawrence Latour
We assessed the utility of a brief MRI protocol, appropriate for the acute setting, to detect acute traumatic brain injury (TBI) in patients with suspected mild TBI (mTBI) and distinguish traumatic from non-traumatic brain injury by comparing to non-trauma patients. Twenty-two patients with suspected mTBI were included in this exploratory study over a period of 9 months. Median time from injury to MR scanning was 5.4 hours (inter-quartile range 3.6-15.3). To determine the specificity of certain findings for TBI, 61 patients presenting with suspected minor acute stroke were included as comparative group using the same MRI methods...
May 23, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27208397/screening-for-history-of-traumatic-brain-injury-among-women%C3%A2-exposed-to-intimate-partner-violence
#14
Yelena Goldin, Halina L Haag, Charlotte T Trott
Traumatic brain injury (TBI) is a common chronically debilitating consequence of intimate-partner violence (IPV). Diagnosis and effective treatment are precluded by poor detection and lack of uniform practice guidelines for TBI screening in IPV. Although there are several TBI-screening tools commonly used in clinical and research practices, their applicability to this unique and vulnerable population is unclear. In this review paper, we propose a theoretically based framework for screening for history of TBI in women exposed to IPV and apply it to investigate the applicability of TBI-screening instruments...
May 18, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27188531/prp-c-expression-and-calpain-activity-independently-mediate-the-effects-of-closed-head-injury-in-mice
#15
Richard Rubenstein, Kevin K Wang, Allen Chiu, Natalia Grinkina, Deep R Sharma, Sanjeev Agarwal, Fan Lin, Zhihui Yang
The normal cellular prion protein (PrP(C)) is a sialoglycoprotein with a glycophosphatidylinositol anchor and expressed in highest levels within the CNS particularly at neuronal synapses. This membrane-bound protein is involved with many cell functions including cell signaling and neuroprotection. Calpains are calcium-activated cysteine proteases that typically undergo controlled activation. PrP(C) is a calpain substrate and is neurotoxic if it undergoes aberrant processing with cytosol accumulation. Following traumatic brain injury (TBI), there is an abnormal influx of Ca(+2) and overactivation of calpains resulting in neuronal dysfunction and cell death...
May 14, 2016: Behavioural Brain Research
https://www.readbyqxmd.com/read/27156252/traumatic-brain-injury-with-a-machete-penetrating-the-dura-and-brain-case-report-from-southeast-mexico
#16
Juan D Del Castillo-Calcáneo, Ulises Bravo-Angel, Raúl Mendez-Olan, Francisco Rodriguez-Valencia, Javier Valdés-García, Ulises García-González, Guy G Broc-Haro
INTRODUCTION: Traumatic Brain Injury (TBI) is a major cause of death and disability in our society, we present the first case report of non-missile penetrating (NMP) cranial trauma with a machete in Mexico, and our objective by presenting this case is to prove the usefulness of recently proposed algorithms in the treatment of NMP PRESENTATION OF CASE: We present the case of a 47 year old woman who received a machete hit to the right side of her head during an assault., she arrived fully conscious to the emergency department (ED), computed tomography was performed and based on the findings of this study and in accordance to recently proposed algorithms for managing NMP cranial trauma a craniotomy was performed, at follow-up the patient presented wtih minor neurological disability in the form of left hemiparesis...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27153812/genetic-variation-in-neuronal-glutamate-transport-genes-and-associations-with-posttraumatic-seizure
#17
Anne C Ritter, Candace M Kammerer, Maria M Brooks, Yvette P Conley, Amy K Wagner
OBJECTIVE: Posttraumatic seizures (PTS) commonly occur following severe traumatic brain injury (sTBI). Risk factors for PTS have been identified, but variability in who develops PTS remains. Excitotoxicity may influence epileptogenesis following sTBI. Glutamate transporters manage glutamate levels and excitatory neurotransmission, and they have been associated with both epilepsy and TBI. Therefore, we aimed to determine if genetic variation in neuronal glutamate transporter genes is associated with accelerated epileptogenesis and increased PTS risk after sTBI...
June 2016: Epilepsia
https://www.readbyqxmd.com/read/27058675/central-pain-due-to-spinothalamic-tract-injury-caused-by-indirect-head-trauma-following-a-pratfall
#18
Sung Ho Jang, Han Do Lee
OBJECTIVES: This study reports on patients who showed central pain due to injury of the spinothalamic tract (STT) caused by fall without direct head trauma. DESIGN: Prospective study. PARTICIPANTS: Two patients with mild traumatic brain injury (TBI) resulting from a fall were enrolled. Patient 1 was a 21-year-old female who had suffered a pratfall with no history of direct head trauma. She had begun to feel pain in both upper trunk and lower back and the left leg since ~ 5 days after onset: constant tingling and throbbing sensation with allodynia...
2016: Brain Injury: [BI]
https://www.readbyqxmd.com/read/27057220/outcome-in-2068-patients-of-head-injury-experience-at-a-level-1-trauma-centre-in-india
#19
Deepak Agrawal, S Ahmed, S Khan, D Gupta, S Sinha, G D Satyarthee
BACKGROUND: Traumatic brain injury (TBI) is one of the leading causes of death. Evidence-based guidelines for TBI care have been widely discussed, but in-hospital treatment and outcome of these patients has been highly variable especially in developing countries like India. OBJECTIVES: To evaluate the epidemiology and outcome of patients with head injuries at a Level 1 trauma center in India. MATERIALS AND METHODS: In this retro-prospective study, all patients with head injury who were admitted in the department of neurosurgery over a 15 months period (November 2007-January 2009) were included in the study...
April 2016: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/27027558/inhibition-of-platelet-function-is-common-following-even-minor-injury
#20
Sarah Sirajuddin, Carrie Valdez, Louis DePalma, Patrick Maluso, Rishi Singhal, Mary Schroeder, Babak Sarani
BACKGROUND: Hemorrhage remains the leading cause of preventable death following injury. Whereas significant attention has been paid to the coagulation cascade, there are fewer studies evaluating platelet dysfunction following injury. Thrombelastogram platelet mapping (TEG-PM) allows for the measurement of maximal potential clot strength and clot strength selectively caused by arachidonic acid and adenosine disphosphate receptors on the platelet. The purpose of this study was to determine the incidence and magnitude of receptor-specific platelet dysfunction following injury in patients who are not otherwise pharmacologically anticoagulated...
August 2016: Journal of Trauma and Acute Care Surgery
keyword
keyword
11801
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"