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https://www.readbyqxmd.com/read/28195856/pharmacoepidemiologic-analyses-of-opioid-use-among-oef-oif-ond-veterans
#1
Teresa J Hudson, Jacob T Painter, Brad Martin, Mark A Austen, James S Williams, John Fortney, Mark D Sullivan, Mark E Edlund
There is a great deal of concern about opioid use in Veterans, particularly those that served in Afghanistan (OEF) and Iraq (OIF and OND). The current study provides a detailed pharmacoepidemiologic analysis of opioid use among OEF/OIF/OND Veterans from FY09 to FY12. Data from three data repositories from the Veterans Health Administration (VHA) were used to describe demographic, clinical, and medication characteristics associated with opioid use among OEF/OIF/OND Veterans and among those with TBI. Logistic regression models were used to identify risks associated with chronic opioid use in FY12...
February 11, 2017: Pain
https://www.readbyqxmd.com/read/28143728/isolated-internuclear-ophthalmoplegia-after-massive-supratentorial-epidural-hematoma-a-case-report-and-review-of-literature
#2
Ko-Ting Chen, Tzu-Kang Lin, Tsung-Che Hsieh
BACKGROUND: Isolated Internuclear ophthalmoplegia (INO) following traumatic brain injury (TBI) is rare, with the majority of reported patients suffering from minor head injuries. We report a patient with INO after a massive supratentorial epidural hematoma. We review the literature published since 1966, to summarize the mechanisms of injury and clinical outcomes of INO after TBI. CASE DESCRIPTION AND LITERATURE REVIEW: A 54-year-old woman suffered from isolated INO 10 hours after emergent evacuation of a massive supratentorial epidural hematoma...
January 28, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28095027/severe-and-extensive-traumatic-axonal-injury-following-minor-and-indirect-head-trauma
#3
Sung Ho Jang, Han Do Lee
OBJECTIVES: This study reports on a patient with mild traumatic brain injury (TBI) who showed severe and extensive traumatic axonal injury (TAI) of various neural tracts following minor and indirect head trauma, which was demonstrated by diffusion tensor tractography (DTT). CASE DESCRIPTION: A 26-year-old female patient suffered from indirect head trauma resulting from flexion-hyperextension injury after being hit from behind by a slowly moving car. At the time of head trauma, she felt tingling sensation on her four extremities; however, she did not experience loss of consciousness...
January 17, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28060206/tbi-and-treatment-response-in-a-randomized-trial-of-acceptance-and-commitment-therapy
#4
Jessica Bomyea, Ariel J Lang, Paula P Schnurr
OBJECTIVE: Traumatic brain injury (TBI) occurs in a substantial minority of military personnel, and commonly is associated with mental health disorders and postconcussive symptoms (PCS). The implications of TBI for mental health treatment are not well understood. The present study sought to describe psychotherapy response in veterans with and without TBI. DESIGN: This is a secondary analysis from a 2-group randomized controlled trial. SETTING, PARTICIPANTS, AND MEASURES: One hundred and sixty male and female veterans participated in a multisite randomized controlled trial of Acceptance and Commitment Therapy versus Present Centered Therapy; a subset of 129 veterans were included in these analyses...
January 5, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28060203/predictors-of-employment-outcomes-in-veterans-with-traumatic-brain-injury-a-va-traumatic-brain-injury-model-systems-study
#5
Christina Dillahunt-Aspillaga, Risa Nakase-Richardson, Tessa Hart, Gail Powell-Cope, Laura E Dreer, Blessen C Eapen, Scott D Barnett, Dave Mellick, Adam Haskin, Marc A Silva
OBJECTIVES: To examine the length of time to return to work (RTW) among service members and veterans (SM/V) with traumatic brain injury (TBI) and to identify variables predictive of RTW. SETTING: Department of Veterans Affairs Polytrauma Rehabilitation Centers (VA PRC). PARTICIPANTS: SM/V enrolled in the VA PRC Traumatic Brain Injury Model Systems database who were of 18 to 60 years of age and admitted with the diagnosis of TBI. DESIGN: Prospective observational cohort study...
January 5, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28007444/effectiveness-of-an-educational-intervention-on-reducing-misconceptions-among-ethnic-minorities-with-complicated-mild-to-severe-traumatic-brain-injury
#6
Monique R Pappadis, Angelle M Sander, Beata Łukaszewska, Margaret A Struchen, Patrick Leung, Dennis W Smith
OBJECTIVE: To evaluate the effectiveness of an educational intervention designed to reduce traumatic brain injury (TBI)-related misconceptions among blacks and Latinos with complicated mild to severe TBI. DESIGN: Randomized controlled trial with masked 1-month follow-up. SETTING: Community. PARTICIPANTS: Persons (N=52) with complicated mild to severe TBI (mean best day 1 Glasgow Coma Scale score, 11.27±3.89) were randomly recruited from 141 eligible participants (mean age, 37...
December 19, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27901414/cognitive-deficits-and-inflammatory-response-resulting-from-mild-to-moderate-traumatic-brain-injury-in-rats-are-exacerbated-by-repeated-pre-exposure-to-an-innate-stress-stimulus
#7
Michaël Ogier, Amor Belmeguenai, Thomas Lieutaud, Béatrice Georges, Sandrine Bouvard, Emilie Carré, Frédéric Canini, Laurent Bezin
Traumatic brain injury (TBI) is common in both military and civilian populations, and often results in neurobehavioral sequelae that impair quality of life in both patients and their families. Although individuals who are chronically exposed to stress are more likely to experience TBI, it is still unknown whether pre-injury stress influences the outcome after TBI. The present study tested whether behavioral and cognitive long-term outcome after TBI in rats is affected by prior exposure to an innate stress stimulus...
January 13, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27862642/external-validation-of-the-pecarn-head-trauma-prediction-rules-in-japan
#8
Kentaro Ide, Satoko Uematsu, Kenichi Tetsuhara, Satoshi Yoshimura, Takahiro Kato, Tohru Kobayashi
OBJECTIVES: The Pediatric Emergency Care Applied Research Network (PECARN) head trauma prediction rules are used to assist computed tomography (CT) decision-making for children with minor head trauma. Although the PECARN rules have been validated in North America and Europe, they have not yet been validated in Asia. In Japan, there are no clinical decision rules for children with minor head trauma. The rate of head CT for children with minor head trauma in Japan is high since CT is widely accessible across the country...
November 12, 2016: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/27834535/a-retrospective-cohort-study-of-comorbidity-trajectories-associated-with-traumatic-brain-injury-in-veterans-of-the-iraq-and-afghanistan-wars
#9
Mary Jo Pugh, Erin P Finley, Chen-Pin Wang, Laurel A Copeland, Carlos A Jaramillo, Alicia A Swan, Christine A Elnitsky, Luci K Leykum, Eric M Mortensen, Blessen A Eapen, Polly H Noel, Jacqueline A Pugh
OBJECTIVES: To identify and validate trajectories of comorbidity associated with traumatic brain injury in male and female Iraq and Afghanistan war Veterans (IAV). METHODS: Derivation and validation cohorts were compiled of IAV who entered the Department of Veterans Affairs (VA) care and received 3 years of VA care between 2002-2011. Chronic disease and comorbidities associated with deployment including TBI were identified using diagnosis codes. A latent class analysis (LCA) of longitudinal comorbidity data was used to identify trajectories of comorbidity...
2016: Brain Injury: [BI]
https://www.readbyqxmd.com/read/27775489/head-injury-screening-and-intimate-partner-violence-a-brief-report
#10
Kerry L Gagnon, Anne P DePrince
OBJECTIVE: Although the importance of traumatic brain injury has gained public attention in recent years, relatively little attention has been paid to head injuries among women who have experienced intimate partner violence (IPV). The present study screened for lifetime exposure to mild traumatic brain injuries (mTBIs) among a sample of women who had experienced recent IPV (median days since target incident = 26). METHOD: Participants included ethnically diverse women whose IPV experiences were reported to law enforcement...
October 24, 2016: Journal of Trauma & Dissociation
https://www.readbyqxmd.com/read/27764546/the-psychological-impact-of-traffic-injuries-sustained-in-a-road-crash-by-bicyclists-a-prospective-study
#11
A Craig, N A Elbers, J Jagnoor, B Gopinath, A Kifley, M Dinh, I Pozzato, R Q Ivers, M Nicholas, I D Cameron
OBJECTIVE: The objective of this study was to investigate the psychological impact of traffic injuries in bicyclists (cyclists) in comparison to car occupants who also sustained traffic injuries. Factors predictive of elevated psychological distress were also investigated. METHODS: An inception cohort prospective design was used. Participants included cyclists aged ≥17 years (mean age 41.7 years) who sustained a physical injury (n = 238) assessed within 28 days of the crash, following medical examination by a registered health care practitioner...
April 3, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/27741077/acute-outcomes-of-isolated-pneumocephali-in-children-after-minor-blunt-head-trauma
#12
Ashley Blanchard, Keven I Cabrera, Nathan Kuppermann, Peter S Dayan
OBJECTIVES: We aimed to determine the prevalence of and adverse outcomes caused by pneumocephali in children with minor blunt head trauma who had no other intracranial injuries (ie, isolated pneumocephali). METHODS: We conducted a secondary analysis of a public use dataset from a multicenter prospective study of pediatric minor head trauma. We included children younger than 18 years with Glasgow Coma Scale (GCS) scores of 14 or 15 and non-trivial mechanisms of injury who had cranial computed tomographies obtained...
October 6, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27677908/abcc8-single-nucleotide-polymorphisms-are-associated-with-cerebral-edema-in-severe-tbi
#13
Ruchira M Jha, Ava M Puccio, David O Okonkwo, Benjamin E Zusman, Seo-Young Park, Jessica Wallisch, Philip E Empey, Lori A Shutter, Robert S B Clark, Patrick M Kochanek, Yvette P Conley
OBJECTIVE: Cerebral edema (CE) in traumatic brain injury (TBI) is the consequence of multiple underlying mechanisms and is associated with unfavorable outcomes. Genetic variability in these pathways likely explains some of the clinical heterogeneity observed in edema development. A role for sulfonylurea receptor-1 (Sur1) in CE is supported. However, there are no prior studies examining the effect of genetic variability in the Sur1 gene (ABCC8) on the development of CE. We hypothesize that ABCC8 single nucleotide polymorphisms (SNPs) are predictive of CE...
September 27, 2016: Neurocritical Care
https://www.readbyqxmd.com/read/27637440/the-effect-of-prehospital-intubation-on-treatment-times-in-patients-with-suspected-traumatic-brain-injury
#14
Joshua D Lansom, Kate Curtis, Helen Goldsmith, Alex Tzannes
OBJECTIVE: This study examines whether, in patients requiring intubation with moderate to severe traumatic brain injury (TBI), prehospital intubation compared with emergency department intubation leads to a reduction in treatment times and time to a computed tomographic (CT) scan. METHODS: A retrospective cohort study compared adult patients with a Glasgow Coma Score of less than 14 with a suspected TBI who underwent intubation, either prehospital or on arrival to the emergency department...
September 2016: Air Medical Journal
https://www.readbyqxmd.com/read/27322378/equestrian-related-traumatic-brain-injury-in-the-pediatric-population
#15
Ha Son Nguyen, Sean Lew
BACKGROUND: Equestrian activities can be undertaken for competition or leisure. Accidents can lead to bodily injuries. In particular, traumatic brain injury (TBI) can be devastating. Limited data exist regarding the pediatric population with respect to patterns of injury and related neurosurgical intervention. METHODS: We retrospectively reviewed data for all pediatric patients diagnosed with equestrian-related injuries with neurological injuries from 2005 through June 2015...
2016: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27251119/catecholamines-and-paroxysmal-sympathetic-hyperactivity-after-traumatic-brain-injury
#16
Juan F Fernandez-Ortega, Ian J Baguley, Thomas A Gates, Manuel Garcia-Caballero, Juan G Quesada-Garcia, Miguel A Prieto-Palomino
Paroxysmal sympathetic hyperactivity (PSH) affects a significant minority of people in the intensive care unit after severe traumatic brain injury. Systematic research has yet to elucidate or quantify the extent of the role of the catecholamines or adrenocortical and thyroid axis hormonal influences in the condition. Data were prospectively collected on 80 consecutive patients, 18 of whom developed clinical signs of PSH (22.5%). Catecholamine and hormonal data were collected sequentially at 4-h intervals or during and between episodes of PSH...
January 1, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27243415/variation-in-anticonvulsant-selection-and-electroencephalographic-monitoring-following-severe-traumatic-brain-injury-in-children-understanding-resource-availability-in-sites-participating-in-a-comparative-effectiveness-study
#17
Jonathan E Kurz, Samuel M Poloyac, Nicholas S Abend, Anthony Fabio, Michael J Bell, Mark S Wainwright
OBJECTIVES: Early posttraumatic seizures may contribute to worsened outcomes after traumatic brain injury. Evidence to guide the evaluation and management of early posttraumatic seizures in children is limited. We undertook a survey of current practices of continuous electroencephalographic monitoring, seizure prophylaxis, and the management of early posttraumatic seizures to provide essential information for trial design and the development of posttraumatic seizure management pathways...
July 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27224640/transcranial-doppler-to-predict-neurologic-outcome-after-mild-to-moderate-traumatic-brain-injury
#18
Pierre Bouzat, Luc Almeras, Pauline Manhes, Laurence Sanders, Albrice Levrat, Jean-Stephane David, Raphael Cinotti, Russel Chabanne, Aurélie Gloaguen, Xavier Bobbia, Sophie Thoret, Lydia Oujamaa, Jean-Luc Bosson, Jean-François Payen, Karim Asehnoune, Philippe Pes, Jean-Yves Lefrant, Sébastien Mirek, François Albasini, Caron Scrimgeour, Jean-Marc Thouret, Freddy Chartier, Marc Ginet
BACKGROUND: To assess the performance of transcranial Doppler (TCD) in predicting neurologic worsening after mild to moderate traumatic brain injury. METHODS: The authors conducted a prospective observational study across 17 sites. TCD was performed upon admission in 356 patients (Glasgow Coma Score [GCS], 9 to 15) with mild lesions on cerebral computed tomography scan. Normal TCD was defined as a pulsatility index of less than 1.25 and diastolic blood flow velocity higher than 25 cm/s in the two middle cerebral arteries...
August 2016: Anesthesiology
https://www.readbyqxmd.com/read/27215444/trauma-specific-brain-abnormalities-in-suspected-mild-traumatic-brain-injury-patients-identified-in-the-first-48-hours-after-injury-a-blinded-magnetic-resonance-imaging-comparative-study-including-suspected-acute-minor-stroke-patients
#19
Maria Chiara Ricciardi, Reinoud P H Bokkers, John A Butman, Dima A Hammoud, Dzung L Pham, Steven Warach, Lawrence L Latour
We assessed the utility of a brief MRI protocol, appropriate for the acute setting, to detect acute traumatic brain injury (TBI) in patients with suspected mild TBI (mTBI) and distinguish traumatic from nontraumatic brain injury by comparing trauma with nontrauma patients. Twenty-two patients with suspected mTBI were included in this exploratory study over a period of 9 months. Median time from injury to MR scanning was 5.4 h (interquartile range 3.6-15.3). To determine the specificity of certain findings for TBI, 61 patients presenting with suspected minor acute stroke were included as a comparative group using the same MRI methods...
January 1, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27208397/screening-for-history-of-traumatic-brain-injury-among-women%C3%A2-exposed-to-intimate-partner-violence
#20
Yelena Goldin, Halina L Haag, Charlotte T Trott
Traumatic brain injury (TBI) is a common chronically debilitating consequence of intimate-partner violence (IPV). Diagnosis and effective treatment are precluded by poor detection and lack of uniform practice guidelines for TBI screening in IPV. Although there are several TBI-screening tools commonly used in clinical and research practices, their applicability to this unique and vulnerable population is unclear. In this review paper, we propose a theoretically based framework for screening for history of TBI in women exposed to IPV and apply it to investigate the applicability of TBI-screening instruments...
May 18, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
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