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https://www.readbyqxmd.com/read/27755410/the-rate-of-epistaxis-incidence-in-new-generation-anticoagulants-and-perioperative-approach-in-otorhinolaryngological-practices
#1
Ozan Gökdoğan, Ilker Akyildiz, Begum Yetis Sayin, Sercan Okutucu, Ali Cevat Tanalp, Necmi Arslan
Nose bleeding is a common situation seen in otorhinolaryngological practices. One of the greatest risk factors in nose bleeding is the use of anticoagulant medicine. With the medicine developed in recent years, the risk of nose bleeding due to the frequent use of anticoagulant and antiagregant is gradually increasing.The purpose of this study is to determine the effects of especially new-generation anticoagulants on nose bleeding. In addition, the use and complications of new-generation anticoagulants and antiagregants have been compiled in light of information obtained from the literature...
October 14, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27480178/comparison-of-hyperbaric-oxygen-versus-iloprost-treatment-in-an-experimental-rat-central-retinal-artery-occlusion-model
#2
Suleyman Karaman, Berna Ozkan, Yusufhan Yazir, Melda Yardimoglu, Mustafa Gok, Ozgur Kara, Cigdem Vural, Selenay Rencber, Salih K Emek
PURPOSE: Central retinal artery occlusion (CRAO) is one of the serious ophthalmological emergencies with poor visual prognosis. Iloprost is a stable prostacyclin analogue and has prominent anti-edema, anti-inflammatory, vasodilatory, and antiagregant effects. The main objective of this work was to investigate iloprost as an alternative agent versus hyperbaric oxygen (HBO) in the treatment of CRAO. METHODS: Twenty-eight healthy Wistar albino male rats were randomly assigned into control (n = 7, sham operation), HBO (n = 7), iloprost (n = 7), and sham groups (n = 7)...
August 2, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27275349/endothelial-nitric-oxide-synthase-t-786c-mutation-prothrombin-gene-mutation-g-20210-a-and-protein-s-deficiency-could-lead-to-myocardial-infarction-in-a-very-young-male-adult
#3
Milka Klincheva, Elena Ambarkova Vilarova, Tanja Angjusheva, Ivan Milev, Enver Idoski, Zan Mitrev
INTRODUCTION: Myocardial infarction is a rare medical event in young people. The main reasons include congenital coronary abnormalities, coronary artery spasm, and coronary thrombosis due to hypercoagulable states (hereditary and acquired). AIM: We present a case of a young male adult with myocardial infarction caused by a combination of gene mutations and anticoagulation protein deficiency. CASE PRESENTATION: A 19 years old young man was admitted to our hospital complaining of chest pain during the last two weeks...
March 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/26385102/recurrent-acute-coronary-syndrome-and-restenosis-after-percutaneous-coronary-intervention-in-a-patient-with-idiopathic-thrombocytopenic-purpura-a-case-report-and-literature-review
#4
REVIEW
Ge Li-Sha, Chen Peng, Li Yue-Chun
BACKGROUND: Platelets play a pivotal role in the pathogenesis of acute coronary syndrome (ACS) and acute and chronic complications following percutaneous coronary intervention (PCI). Platelet inhibition is a cornerstone in the management of these patients. Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder characterized by premature platelet destruction mediated by autoantibodies. The safety of antiplatelet therapy and PCI in patients who have ACS and ITP is unknown. The aim of the present study is to discuss the management strategies for patients who have ACS and ITP and to review limited data available in the literature...
September 18, 2015: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/25656332/acute-myocardial-infarction-with-concomitant-pulmonary-embolism-as-a-result-of-patent-foramen-ovale
#5
Mert İlker Hayıroğlu, Emrah Bozbeyoğlu, Şükrü Akyüz, Özlem Yıldırımtürk, Mehmet Bozbay, Nijad Bakhshaliyev, Emir Renda, Gülay Gök, Mehmet Eren, Seçkin Pehlivanoğlu
Acute myocardial infarction (MI) and pulmonary embolism canal one lead to life-threatening conditions such as sudden cardiac death and congestive heart failure. We discuss a case of a 74-year-old man presented to the emergency department with acute dyspnea and chest pain. Acute anterior MI and pulmonary embolism concomitantly were diagnosed. Primary percutaneous coronary intervention performed because of preliminary acute anterior MI diagnosis. Transthoracic echocardiography was performed to determine further complications caused by acute MI because patient had a continuous tachycardia and dyspnea although hemodynamically stable...
July 2015: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/25416217/-modern-tendencies-in-co-morbid-conditions
#6
K Ischeykin, M Potyazhenko, N Lyulka, N Sokolyuk, G Khaymenova
The present manuscript reviews frequency of the concomitance of Ischaemic Heart Disease (IHD) with Chronic Obstructive Pulmonary Disease (COPD). The conclusion has been drawn, that quite a large group of patients (25.9%) suffers from pulmonary pathology concomitant with disorders of cardio-coronary system. 97 patients (84 male and 13 female) with concomitant IHD and COPD (steady cardiac angina FK II st.) have been admitted with acute pulmonary condition, and examined at the Department of Pulmonology at N.V...
October 2014: Georgian Medical News
https://www.readbyqxmd.com/read/24861225/-psychosis-as-debut-of-antiphospholipid-syndrome
#7
REVIEW
Lucía del Rio-Casanova, Eduardo Paz-Silva, Ignacio Requena-Caballero, Francisco Diaz-Llenderrozas, Jesús Gomez-Trigo Baldominos, Alberto de la Cruz-Davila, Mario Paramo-Fernandez
INTRODUCTION: Antiphospholipid syndrome (APS) is an autoimmune disorder which causes an hypercoagulation state characterized by thrombotic events, repetitive miscarriages and the presence of antiphospholipid antibodies. APS may be an isolated disease (primary APS) or associated to systemic lupus erythematous or another autoimmune conditions (secondary APS). Neuropsychiatric manifestations accompanying APS include migraine, epilepsy, chorea, dementia or psychosis. Detailed descriptions of clinical cases are lacking, and correlations between clinical and analytical findings are far from being well known...
June 1, 2014: Revista de Neurologia
https://www.readbyqxmd.com/read/24738260/-features-of-antiagregant-and-anticoagulant-therapy-at-a-hybrid-revascularization-of-a-myocardium-in-elderly-and-senile-patients
#8
REVIEW
G G Khubulava, K L Kozlov, S S Mikhaĭlov, A N Shishkevich, I B Oleksiuk
The hybrid revascularization of a myocardium combines advantages of mammaro-coronary shunting and stenting of coronary arteries and represents the perspective direction in coronary heart disease treatment. This technique is of most value in patients of advanced and senile age, and also in patients of high surgical risk as it shows small injury, which enables to reduce and facilitate the postoperative period. However today, there is no single standard for the execution of these operations, in particular it is not clear, which scheme of antiagregant and anticoagulant therapy is worth adhering for greater efficiency of the procedures and patient safety...
2013: Advances in Gerontology, Uspekhi Gerontologii
https://www.readbyqxmd.com/read/22579299/-risk-factors-of-upper-gastrointestinal-complications-in-outpatients-on-antiplatelet-therapy-description-and-management
#9
MULTICENTER STUDY
G Ducrocq, M-A Bigard, S Marouene, P-H Delaage, C Fabry, P Barthelemy, P-G Steg
OBJECTIVES: Patients on antiplatelet therapy have a gastrointestinal bleeding risk. It is increased by risk factors. The frequency of those risk factors, the prevalence of upper digestive symptoms and their management in patients on antiplatelet agents is unknown. PATIENTS AND METHODS: We performed an observational multi-centred prospective survey among 560 French cardiologists with private practice. Each cardiologist completed a questionnaire for the first four patients treated with antiplatelet agents in primary or secondary prevention...
August 2012: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/22263347/-acute-coronary-syndrome-clinical-and-therapeuthics-patterns
#10
José Ramón de Berrazueta Fernández
Acute Coronary Syndrome (ACS) are classified by the mechanisms of thrombosis that induce the complete of partial occlusion of coronary artery, with two tipes of ST changes in ECG. ACS with ST segment elevation (ACSSTE) is induced by a completed thrombotic occlusion by a red thrombus, it need a rapid and complete restoration of coronary artery blood flow with myocardial reperfusion in the first six hours after starting with pain. This is the mechanism by which reperfusion therapy reduces morbidity and mortality...
2010: Anales de la Real Academia Nacional de Medicina
https://www.readbyqxmd.com/read/22136914/surgical-hemostatic-agents-assessment-of-drugs-and-medical-devices
#11
REVIEW
R Aubourg, J Putzolu, S Bouche, H Galmiche, C Denis, A d'Andon, D Maitrot, C Partensky
Surgical hemostatic agents are indicated to improve hemostasis when conventional techniques (compression, sutures or electrocoagulation) are inadequate. The National French Authority for Health (Haute Autorité de santé [HAS]) set out to assess these products (medical devices and agents) to determine their optimal utility. This evaluation included one class of products containing some form of human fibrinogen and thrombin and eight classes of medical devices and automated devices to prepare autologous fibrin...
December 2011: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/21829057/-changes-in-parameters-of-coagulation-system-after-treatment-of-chronic-heart-failure-with-%C3%AE-adrenoblockers-angiotensin-converting-enzyme-inhibitors-calcium-antagonists-diuretics-anticoagulants-antiagregants-cardiac-glycosides-and-physical-exercise
#12
REVIEW
Aušra Mongirdienė
Scientific research has proved that coagulation system is more active in patients with chronic heart failure than in healthy people. Therefore, the aim of this article was to review the data in literature about changes in coagulation system after treatment of chronic heart failure with β-adrenoblockers, angiotensin-converting enzyme (ACE) inhibitors, calcium antagonists, cardiac glycosides, diuretics, anticoagulants, and antiagregants. It is known that β-adrenoblockers used separately decrease platelet aggregation and angiotensin-converting enzyme inhibitors reduce P-selectin expression as well...
2011: Medicina
https://www.readbyqxmd.com/read/21770682/antiagregation-and-anticoagulation-relationship-with-upper-gastrointestinal-bleeding
#13
Philip Wikman Jorgensen, Eva López Calleja, Pablo Safont Gasó, Mariano Matarranz del Amo, Raquel Andrés Navarro, Jaime Merino Sánchez
INTRODUCTION: the high prevalence of cardiovascular diseases in the modern society brings a high prescription of platelet antiaggregation and anticoagulant medications. These treatments have been related to an increased incidence of upper gastrointestinal bleedings (UGB). Our aim was to estimate the fraction of UGB´s presented to our hospital that was related to this kind of treatments and describe their clinical features in our environment. MATERIAL AND METHODS: a retrospective search was performed in the archives of our hospital of all the patients with diagnosis of UGB admitted during the period 2004-2007 both years inclusive...
July 2011: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/21751542/-seniors-and-cardiovascular-medications
#14
REVIEW
H Matejovská Kubesová, P Weber, H Meluzínová, J Matejovský
Authors analyze the situation in the therapy of cardiovascular diseases--unsatisfactory situation especially from the dyslipidaemia point of view. Different groups of medications are discussed and their risks for elderly patients. Angiotensin converting enzyme blockers and their influence on the endothelial dysfunction, but the risk of hyperpotassemia are showed. The risk of gastrointestinal bleeding during the treatment with antiagregants and anticoagulants, the risk of bradycardia in beta-blockade, possible interactions with other medications lowering the heart rate are discussed...
June 2011: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/21495330/-benzimidazo-pyrimidino-imidazo-thiadiazines-pharmacologically-active
#15
Georgeta Rusu, Lenuţa Profire, Gh Dănilă
UNLABELLED: The compounds with thiadiazine structure have numerous biological properties. They are known for antimycotic, antimicrobial, antiviral, vasodilatatory, antiarytmic, bronhodilatatory and antiagregant actions. MATERIAL AND METHOD: In order to study the influence of the different substituents on pharmacological properties of the thiadiazine compounds new benzimidazo-pyrimidino-imidazo-thiadiazine derivatives with potential biological actions have been synthesized...
January 2009: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://www.readbyqxmd.com/read/21414891/-metastatic-cutaneous-hematoma-variant-from-melanoma-five-cases
#16
Anne Pham-Ledard, Alain Taieb, Béatrice Vergier, Thomas Jouary
INTRODUCTION: Melanoma is an aggressive tumor with high metastatic potential. We described herein five patients with metastatic cutaneous hematoma variant from melanoma. OBSERVATIONS: Patients were four men and one woman, four were already known for melanoma. In one case, the occurrence of hematoma leads to the diagnosis of metastatic melanoma. These hematomas were true hematomas, which had appeared spontaneously and in some cases a nodule or lymphadenopathy was clinically found...
February 2011: Bulletin du Cancer
https://www.readbyqxmd.com/read/20681466/-brno-register-2-post-myocardial-infarction-pharmacotherapy
#17
J Spinar, O Ludka, M Sepsi, J Schildberger, L Dusek, J Jarkovský et al.
We assessed 850 patients with a history of myocardial infarction >1 month ago who attended outpatient clinics of the Clinic of Internal Medicine and Cardiology at the Faculty Hospital Brno between 1st September 2009 and 31st December 2009. There were more men (650 vs. 200) and patients under 70 years of age (576 vs. 264) in the cohort. 87.8% of patients experienced one myocardial infarction only and the mean age at the first infarction was 59.0 years in men and 65.5 in women (p < 0.001). 75.8% of patients had been prescribed all recommended pharmacotherapeutic groups according to guidelines (RAAS blockers, beta-blockers, statins, antiagregation agents) and each group individually was used in > 90% of patients...
June 2010: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/20217643/-dissections-of-craniocervical-arteries-in-the-paediatric-age-a-pathology-that-is-emerging-or-under-diagnosed
#18
María Eugenia Russi, Gabriel González, Roberto Crosa, Belén Pérez-Dueñas, Verónica González-Alvarez, Jaume Campistol, Teresa Solá-Martínez
INTRODUCTION: Cranio-cervical arterial dissections are a recognized cause of ischemic stroke in childhood, with an approximate incidence of 0.4 to 20%. AIM. To describe a population of children with cranio-cervical arterial dissections, analyzing clinical presentation, risk factors, angiographic findings, evolution and treatment. PATIENTS AND METHODS: A descriptive, retrospective, longitudinal collaborative review (Sant Joan de Deu and Pereira Rossell Children's Hospital), of children one month to 17 years old of age was conducted, during the period of time between 2000 to 2009...
March 1, 2010: Revista de Neurologia
https://www.readbyqxmd.com/read/18712096/-module-of-hypercoagulation-as-a-biomarker-for-estimation-of-hemostasis-risk-factor-of-thrombosis-determination-of-an-individual-antiaggregant-dose-and-the-way-of-its-use-in-patients-with-arterial-hypertension
#19
S M Tolstopiatov
12 patients with stage II arterial hypertantion have been administered a complex therapy including antihypertensive, hypocholesterolemic (statines), and antiagregant (aspirin, acelisin) agents as a preventive maintenance of vascular complications (stroke, myocardial infarction). Optimization of individual treatment was established by controlling parameters of the integrated indicator of the coagulation cascade of whole blood. This indicator is called the coagulation module (CM). In a clinical practice this biomarker favours qualitative assessment of disorders of the coagulation potential and degree of its dysfunction...
2007: Likars'ka Sprava
https://www.readbyqxmd.com/read/18314650/-orthotopic-renal-transplant-our-experience
#20
R De Gracia, C Jiménez, F Gil, F Escuin, A Tabernero, A Sanz, L Hidalgo
UNLABELLED: Orthotopic renal transplant (ORT) is useful in cases of severe atherosclerosis, heterotopic bilateral transplant, unsuitable pelvic vessels and in aortic thrombosis, but it is not available in all the institutions and it is only realized of exceptional form. AIM: To review the indication, surgical technique and outcome of the ORT at our hospital. MATERIAL AND METHODS: The studied included five cases between January 1990 and December 2005...
November 2007: Actas Urologicas Españolas
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