keyword
MENU ▼
Read by QxMD icon Read
search

Fluids therapy

keyword
https://www.readbyqxmd.com/read/29906569/salival-%C3%AE-iduronidase-activity-as-a-potential-new-biomarker-for-the-diagnosis-and-monitoring-the-effect-of-therapy-in-mucopolysaccharidosis-i
#1
Jaap van Doorn, Brigitte T A van den Broek, Ans J Geboers, Gé-Ann Kuiper, J J Boelens, Peter M van Hasselt
Although disease progression in Mucopolysaccharidosis I (MPS-1) can be attenuated by hematopoietic cell transplantation (HCT), it is increasingly recognized that residual disease is substantial. Biomarkers that would allow us to evaluate the efficacy of HCT (and upcoming new therapies) in non-hematological tissues are needed. Current biomarkers, including the iduronidase (IDUA) activity in leukocytes, are not suitable for this purpose as they are assessed in tissues of hematological origin and may not reflect enzyme availability in non-hematologic tissues...
June 12, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29905851/immune-regulation-by-cd169-macrophages
#2
Kenichi Asano, Kenta Kikuchi, Masato Tanaka
Tissue macrophages comprise heterogeneous subsets that differ in localization, phenotype, and ontogeny. They acquire tissue-specific phenotype in order to maintain normal tissue physiology. This review summarizes the current knowledge about the functions of CD169-positive macrophage subset residing in the lymphoid organs and intestinal tract. Strategically positioned at the interface between tissue and circulating fluid, CD169+ macrophages in the lymphoid organs capture blood- and lymph-borne particulate materials...
June 14, 2018: Journal of Biochemistry
https://www.readbyqxmd.com/read/29905844/robotic-assisted-mri-guided-interventional-interstitial-mr-guided-focused-ultrasound-ablation-in-a-swine-model
#3
Jacquelyn MacDonell, Niravkumar Patel, Gregory Fischer, E Clif Burdette, Jiang Qian, Vaibhav Chumbalkar, Goutam Ghoshal, Tamas Heffter, Emery Williams, Matthew Gounis, Robert King, Juliette Thibodeau, Gene Bogdanov, Olivia W Brooks, Erin Langan, Roy Hwang, Julie G Pilitsis
BACKGROUND: Ablative lesions are current treatments for epilepsy and brain tumors. Interstitial magnetic resonance (MR) guided focused ultrasound (iMRgFUS) may be an alternate ablation technique which limits thermal tissue charring as compared to laser therapy (LITT) and can produce larger ablation patterns nearer the surface than transcranial MR guided focused ultrasound (tcMRgFUS). OBJECTIVE: To describe our experience with interstitial focused ultrasound (iFUS) ablations in swine, using MR-guided robotically assisted (MRgRA) delivery...
June 14, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29904927/mesenchymal-stromal-cells-from-amniotic-fluid-are-less-prone-to-senescence-compared-to-those-obtained-from-bone-marrow-an-in-vitro-study
#4
Nicola Alessio, Caterina Pipino, Domitilla Mandatori, Pamela Di Tomo, Angela Ferone, Marco Marchiso, Mariarosa A B Melone, Gianfranco Peluso, Assunta Pandolfi, Umberto Galderisi
Mesenchymal stromal cells (MSCs) are considered to be an excellent source in regenerative medicine. They contain several cell subtypes, including multipotent stem cells. MSCs are of particular interest as they are currently being tested using cell and gene therapies for a number of human diseases. They represent a rare population in tissues; for this reason, they require, before being transplanted, an in vitro amplification. This process may induce replicative senescence, thus affecting differentiation and proliferative capacities...
June 15, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29904646/spatial-relationship-between-bone-formation-and-mechanical-stimulus-within-cortical-bone-combining-3d-fluorochrome-mapping-and-poroelastic-finite-element-modelling
#5
A Carrieroa, A F Pereirab, A J Wilson, S Castagno, B Javaheri, A A Pitsillides, M Marenzana, S J Shefelbine
Bone is a dynamic tissue and adapts its architecture in response to biological and mechanical factors. Here we investigate how cortical bone formation is spatially controlled by the local mechanical environment in the murine tibia axial loading model (C57BL/6). We obtained 3D locations of new bone formation by performing 'slice and view' 3D fluorochrome mapping of the entire bone and compared these sites with the regions of high fluid velocity or strain energy density estimated using a finite element model, validated with ex-vivo bone surface strain map acquired ex-vivo using digital image correlation...
June 2018: Bone Reports
https://www.readbyqxmd.com/read/29903755/severity-scoring-of-lung-oedema-on-the-chest-radiograph-is-associated-with-clinical-outcomes-in-ards
#6
Melissa A Warren, Zhiguou Zhao, Tatsuki Koyama, Julie A Bastarache, Ciara M Shaver, Matthew W Semler, Todd W Rice, Michael A Matthay, Carolyn S Calfee, Lorraine B Ware
BACKGROUND: There is no accurate, non-invasive measurement to estimate the degree of pulmonary oedema in acute respiratory distress syndrome (ARDS). We developed the Radiographic Assessment of Lung Oedema (RALE) score to evaluate the extent and density of alveolar opacities on chest radiographs. After first comparing the RALE score to gravimetric assessment of pulmonary oedema in organ donors, we then evaluated the RALE score in patients with ARDS for its relationship to oxygenation and clinical outcomes...
June 14, 2018: Thorax
https://www.readbyqxmd.com/read/29902914/cytologic-diagnosis-of-metastatic-alveolar-rhabdomyosarcoma-in-cerebrospinal-fluid-a-case-report
#7
Bobae Shim, Jiwon Koh, Ji Hye Moon, In Ae Park, Han Suk Ryu
Rhabdomyosarcoma is a malignant soft tissue tumor which shows skeletal muscle differentiation. Leptomeningeal metastasis can occur as a late complication, but currently there are no reports that have documented the cytologic features in cerebrospinal fluid (CSF). We report a case of metastatic alveolar rhabdomyosarcoma diagnosed in the CSF of a 28-year-old male who was originally diagnosed with rhabdomyosarcoma on the neck, and that went through systemic therapy. The tumor was positive for anaplastic lymphoma kinase, but progressed despite additional therapy with crizotinib...
June 14, 2018: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/29901770/serotonin-syndrome-in-obstetrics-a-case-report-and-review-of-management
#8
Capt Heisy B Asusta, Maj Erin Keyser, Patricia Dominguez, Marvin Miller
Serotonin syndrome (SS) is a life-threatening condition, usually precipitated by a combination of serotonergic agents. Data regarding the incidence and management of SS in obstetrics are limited. This study presents a case of SS provoked by an atypical antipsychotic in a second trimester, singleton gestation, and reviews the management of SS in an obstetric patient. We present a case of a schizophreniform, pregnant patient with a singleton gestation admitted to a community, military hospital for serotonin syndrome...
June 13, 2018: Military Medicine
https://www.readbyqxmd.com/read/29901648/purulent-meningitis-caused-by-rhodococcus-equi-a-case-report
#9
Le-Xiang Cui, Li-Na Gu, Yan-Bo Hou, Bei-Lin Zhang, Jing-Yao Liu
RATIONALE: Purulent meningitis refers infection of the subarachnoid space by various purulent bacteria and the corresponding inflammation of the leptomeninges. However, purulent meningitis due to Rhodococcus equi is extremely rare. PATIENT CONCERNS: A 40-year-old man presented with fever and intermittent headache for 6 days. Two hours prior to admission, he developed epileptic seizures. DIAGNOSES: Brain computed tomography and magnetic resonance imaging showed intracerebral malacic lesions...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29901631/neurological-melioidosis-burkholderia-pseudomallei-in-a-chronic-psychotic-patient-treated-with-antipsychotics-a-case-report
#10
Guan-Bo Chen, Sheng-Hui Tuan, Li-Hsiang Chen, Wen-Sou Lin
RATIONALE: Neurological melioidosis, an extremely rare condition, is caused by the gram-negative bacterium Burkholderia pseudomallei. If treatment is suboptimal or delayed, this infection can produce diverse clinical symptoms and result in death. PATIENT CONCERNS: A healthy 65-year-old female who had been treated with antipsychotic medication for neurotic depression for over 2 years presented with acute-onset fever, headache, lead-pipe rigidity of all limbs, and delirium...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29901586/eosinophilic-meningitis-caused-by-angiostrongylus-cantonensis-in-an-infant-a-case-report
#11
Mingsheng Ma, Mengqi Zhang, Zhengqing Qiu
RATIONALE: Parasitic eosinophilic meningitis is rarely observed in infants. The diagnosis of this disease is complicated by its atypical and severe clinical manifestations. PATIENT CONCERNS: An infant presented to our hospital with high fever and irritability, as well as refusal to walk. Cerebrospinal fluid collected through lumbar puncture showed increased eosinophil count and third-stage Angiostrongylus cantonensis larvae. DIAGNOSES: Eosinophilic meningitis was suspected...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29901576/anterior-interhemispheric-approach-for-removing-large-sellar-region-tumor
#12
Shi-Yu Feng, Tao Zhou, Zheng-Hui Sun, Bo Bu, Jin-Li Jiang
The aim of the study was to explore anterior interhemispheric approach microsurgery for removing large sellar region tumors.A total of 118 patients with large sellar region tumors were treated with the anterior interhemispheric approach microsurgery. There were 58 craniopharyngioma, 37 pituitary adenoma, 5 hypothalamic glioma, 7 meningioma, and 11 other tumors cases. The maximal tumor diameter ranged from 3.0 to 8.2 cm, with a mean diameter of 4.3 cm. Diabetes insipidus and fluid and electrolyte imbalance were timely controlled after surgery...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29900909/effect-of-nonsurgical-periodontal-therapy-on-interleukin-34-levels-in-periodontal-health-and-disease
#13
C N Guruprasad, A R Pradeep
Background: Interleukin-34 (IL-34) is a recently identified alternative ligand for colony-stimulating factor-1 receptor plays an important role in osteoclastogenesis. The aim of this study was to evaluate the IL-34 levels in gingival crevicular fluid (GCF) and plasma in subjects with chronic periodontitis and to evaluate the effect of nonsurgical periodontal therapy on the GCF and plasma IL-34 levels. Materials and Methods: Thirty individuals (age range: 30-56 years) were selected and divided into groups based on the gingival index, probing pocket depth, clinical attachment level, and radiologic parameters (bone loss): Group I (15 individuals with healthy periodontium), Group II (15 individuals with chronic generalized periodontitis) while Group II patients after 8 weeks of the treatment (scaling and root planning) constituted Group III...
May 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29900535/high-throughput-proteomic-analysis-of-candidate-biomarker-changes-in-gingival-crevicular-fluid-after-treatment-of-chronic-periodontitis
#14
Y A Guzman, D Sakellari, K Papadimitriou, C A Floudas
BACKGROUND AND OBJECTIVE: Untargeted, high-throughput proteomics methodologies have great potential to aid in identifying biomarkers for the diagnosis of periodontal disease. The application of such methods to the discovery of candidate biomarkers for the resolution of periodontal inflammation after periodontal therapy has been investigated. MATERIAL AND METHODS: Gingival crevicular fluid samples were collected from 10 patients diagnosed with chronic periodontitis at baseline and 1, 5, 9 and 13 weeks after completion of mechanical periodontal treatment...
June 14, 2018: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29899849/lymph-microvascularization-as-a-prognostic-indicator-in-neuroblastoma
#15
Irene Tadeo, Esther Gamero-Sandemetrio, Ana P Berbegall, Marta Gironella, Félix Ritort, Adela Cañete, Gloria Bueno, Samuel Navarro, Rosa Noguera
Neuroblastoma is the most common extra-cranial solid pediatric cancer and causes approximately 15% of all childhood deaths from cancer. Although lymphatic vasculature is a prerequisite for the maintenance of tissue fluid balance and immunity in the body, little is known about the relationship between lymphatic vascularization and prognosis in neuroblastoma. We used our previously-published custom-designed tool to close open-outline vessels and measure the density, size and shape of all lymphatic vessels and microvascular segments in 332 primary neuroblastoma contained in tissue microarrays...
May 25, 2018: Oncotarget
https://www.readbyqxmd.com/read/29898478/-canine-hypoadrenocorticism-an-update-on-pathogenesis-diagnosis-and-treatment
#16
Katja Kalenyak, Romy M Heilmann
Canine hypoadrenocorticism (HoAC) results from a loss of functional adrenal cortex, the most common etiology of which is an immune-mediated destruction leading to an inadequate production of glucocorticoids and mineralocorticoids. The term "atypical" HoAC is used for a subgroup of dogs with either an isolated glucocorticoid deficiency or a combined glucocorticoid and mineralocorticoid deficiency but normal electrolytes. Dogs with HoAC can present with a large variety of clinical signs, ranging from shaking, weakness, and mild gastrointestinal signs to seizures, hypovolemic shock, and collapse...
June 2018: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/29898249/treatment-of-acute-kidney-injury-secondary-to-oak-intoxication-with-hemodialysis-in-a-miniature-zebu
#17
Rachel B Davy-Moyle, Leo Londoño, Elizabeth A Nelson, Carsten Bandt
OBJECTIVE: To describe the successful management of acute kidney injury (AKI) secondary to oak intoxication using hemodialysis in a miniature zebu. CASE SUMMARY: A 1-year-old male intact miniature zebu was presented for evaluation of a 2-day history of lethargy, anorexia, decreased urine production, and dry, firm stool. Initial diagnostics revealed severe azotemia and the bull was presumptively diagnosed with AKI secondary to oak intoxication due to free access to oak trees in the pasture...
June 13, 2018: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/29897791/macrophage-rac2-is-required-to-reduce-the-severity-of-cigarette-smoke-induced-pneumonia
#18
Jennifer L Larson-Casey, Linlin Gu, Patricia L Jackson, David E Briles, Joanetha Y Hale, J Edwin Blalock, J Michael Wells, Jessy S Deshane, Yong Wang, Dana Davis, Veena B Antony, Adriana V F Massicano, Suzanne E Lapi, A Brent Carter
RATIONALE: Cigarette smoking is prevalent in the U.S. and is the leading cause of preventable diseases. A prominent complication of smoking is an increase in lower respiratory tract infections (LRTI). Although LRTIs are known to be increased in subjects that smoke, the mechanism(s) by which this occurs is poorly understood. OBJECTIVES: Determine how cigarette smoke (CS) reduced reactive oxygen species (ROS) production by the phagocytic NADPH oxidase (NOX2), which is essential for innate immunity in lung macrophages...
June 13, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29897466/increased-activity-of-linezolid-in-combination-with-rifampicin-in-a-murine-pneumonia-model-due-to-mrsa
#19
Yu-Feng Zhou, Yan Q Xiong, Meng-Ting Tao, Liang Li, Ming-Xiao Bu, Jian Sun, Xiao-Ping Liao, Ya-Hong Liu
Objectives: The chloramphenicol/florfenicol resistance gene cfr, which mediates cross-resistance to linezolid and other classes of antimicrobial agents, represents a global therapeutic challenge due to its dissemination among MDR nosocomial pathogens, including MRSA. This study aimed to compare the efficacy of the linezolid/rifampicin combination in a murine pneumonia model caused by cfr-positive and cfr-negative clinical MRSA strains. Methods: Synergistic activity between linezolid and rifampicin was evaluated by chequerboard and time-kill assays...
April 20, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29896664/neurological-disorders-associated-with-human-alphaherpesviruses
#20
Jun-Ichi Kawada
Herpes simplex virus (HSV) encephalitis is the most common cause of sporadic fatal encephalitis worldwide, and central nervous system (CNS) involvement is observed in approximately one-third of neonatal HSV infections . In recent years, single-gene inborn errors of innate immunity have been shown to be associated with susceptibility to HSV encephalitis . Temporal lobe abnormalities revealed by magnetic resonance imaging-the most sensitive imaging method for HSV encephalitis-are considered strong evidence for the disease...
2018: Advances in Experimental Medicine and Biology
keyword
keyword
117993
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"