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Elastomerics

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https://www.readbyqxmd.com/read/28087135/surgical-site-infection-related-to-use-of-elastomeric-pumps-in-pectus-excavatum-repair-lessons-learned-from-root-cause-analysis
#1
Nadja Apelt, Joshua Schaffzin, Christina Bates, Rebeccah L Brown, Marc Mecoli, Senthilkumar Sadhasivam, Victor Garcia
BACKGROUND: Pectus excavatum repair (PEX) is among the most painful thoracic procedures performed. Continuous peripheral nerve blockade (CPNB) is known to be efficacious in optimizing pain control while limiting narcotic use in adult thoracic procedures. It was introduced in May 2015 as a bridge to oral pain control in children undergoing PEX. Consequently, the surgical site infection (SSI) rate increased from 2.7% to 27.7%. METHODS: SSI surveillance followed national guidelines...
January 6, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28080024/direct-fabrication-of-micro-nano-patterned-surfaces-by-vertical-directional-photofluidization-of-azobenzene-materials
#2
Jaeho Choi, Wonhee Cho, Yeon Sik Jung, Hong Suk Kang, Hee-Tak Kim
Anisotropic movement of azobenzene materials (i.e., azobenzene molecules incorporated in polymer, glass, or supramolecules) has provided significant opportunities for the fabrication of micro/nanoarchitectures. The examples include circular holes, line gaps, ellipsoidal holes, and nanofunnels. However, all of the previous studies have only focused on the lateral directional movement for the structural shaping of azobenzene materials. Herein, we propose structural shaping based on a vertical directional movement of azobenzene materials...
January 12, 2017: ACS Nano
https://www.readbyqxmd.com/read/28079812/the-efficacy-of-elastomeric-patient-control-module-when-connected-to-a-balloon-pump-for-postoperative-epidural-analgesia-a-randomized-noninferiority-trial
#3
Myung Hwa Kim, Yon Hee Shim, Min-Soo Kim, Yang-Sik Shin, Hyun Joo Lee, Jeong Soo Lee
When considering the principles of a pain control strategy by patients, reliable administration of additional bolus doses is important for providing the adequate analgesia and improving patient satisfaction. We compared the efficacy of elastomeric patient-control module (PCM) with conventional PCM providing epidural analgesia postoperatively.A noninferiority comparison was used. Eighty-six patients scheduled for open upper abdominal surgery were randomized to use either an elastomeric or conventional PCM connected to balloon pump...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28077048/baxter-elastomeric-pumps-weighing-as-an-alternative-to-visual-inspection
#4
Ellen L Cusano, Raafi Ali, Michael B Sawyer, Carole R Chambers, Patricia A Tang
Purpose Elastomeric pumps are used to administer 46-hour infusions of 5-fluorouracil (5FU). Baxter suggests patients visually monitor their pumps to ensure that infusions are proceeding correctly. This can be confusing and lead to concerns about under- or over-dosing. Baxter has not considered weighing pumps as a validated method for monitoring. This study aims to validate weighing as a more accurate method for patients and healthcare professionals, and describe real life Baxter Infusor™ variability. Methods Patients who had been started on a 46-hour 5FU infusion returned to the clinic approximately 24 h after starting treatment...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/28074028/assessment-of-postoperative-pain-control-with-an-elastomeric-pain-pump-following-cardiothoracic-surgery
#5
Anuvrat Chopra, Jeff Hurren, Susan Szpunar, Stephanie B Edwin
OBJECTIVE: To assess the effectiveness of local anesthesia, delivered via elastomeric pump to manage pain in patients undergoing cardiothoracic surgery. METHODS: A retrospective, comparative analysis evaluating adult cardiothoracic surgery patients (by median sternotomy) who received continuous infusion bupivacaine + traditional methods of pain control (N = 100) or traditional pain control alone (N = 100) from July 2011-October 2013. The primary efficacy end point was total postoperative opioid requirements for 96 hours following surgery...
January 10, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28069498/poly-glycerol-sebacate-poly-%C3%AE%C2%B5-caprolactone-blend-nanofibrous-scaffold-as-intrinsic-bio-and-immunocompatible-system-for-corneal-repair
#6
Sahar Salehi, Marta Czugala, Piotr Stafiej, Mohammadhossein Fathi, Thomas Bahners, Jochen S Gutmann, Bernhard B Singer, Thomas A Fuchsluger
: A major challenge in corneal tissue engineering and lamellar corneal transplantation is to develop synthetic scaffolds able to simulate the optical and mechanical properties of the native cornea. As a carrier, the graft scaffolds should provide the basis for anchorage, repair and regeneration. Although quite a number of scaffolds have been engineered to date, they have not been able to simultaneously recapitulate chemical, mechanical, and structural properties of the corneal extracellular matrix (ECM)...
January 6, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28066874/the-effect-of-a-lidocaine-prilocaine-topical-anesthetic-on-pain-and-discomfort-associated-with-orthodontic-elastomeric-separator-placement
#7
M Abu Al-Melh, L Andersson
BACKGROUND: The initial placement of orthodontic elastomeric separators can be uncomfortable and painful. Therefore, it is important to relieve this disturbing sensation to create a discomfort or pain-free orthodontic visit. The purpose of this study was to investigate the effect of a lidocaine/prilocaine topical anesthetic on pain and discomfort associated with the placement of orthodontic elastomeric separators. METHODS: Fifty subjects aging between 20-35 years were included in this study...
December 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/28060878/soft-modular-robotic-cubes-toward-replicating-morphogenetic-movements-of-the-embryo
#8
Andrea Vergara, Yi-Sheng Lau, Ricardo-Franco Mendoza-Garcia, Juan Cristóbal Zagal
In this paper we present a new type of simple, pneumatically actuated, soft modular robotic system that can reproduce fundamental cell behaviors observed during morphogenesis; the initial shaping stage of the living embryo. The fabrication method uses soft lithography for producing composite elastomeric hollow cubes and permanent magnets as passive docking mechanism. Actuation is achieved by controlling the internal pressurization of cubes with external micro air pumps. Our experiments show how simple soft robotic modules can serve to reproduce to great extend the overall mechanics of collective cell migration, delamination, invagination, involution, epiboly and even simple forms of self-reconfiguration...
2017: PloS One
https://www.readbyqxmd.com/read/28054661/soft-porous-silicone-rubbers-with-ultra-low-sound-speeds-in-acoustic-metamaterials
#9
Abdoulaye Ba, Artem Kovalenko, Christophe Aristégui, Olivier Mondain-Monval, Thomas Brunet
Soft porous silicone rubbers are demonstrated to exhibit extremely low sound speeds of tens of m/s for these dense materials, even for low porosities of the order of a few percent. Our ultrasonic experiments show a sudden drop of the longitudinal sound speed with the porosity, while the transverse sound speed remains constant. For such porous elastomeric materials, we propose simple analytical expressions for these two sound speeds, derived in the framework of Kuster and Toksöz, revealing an excellent agreement between the theoretical predictions and the experimental results for both longitudinal and shear waves...
January 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28054062/stretching-induced-wrinkling-in-plastic-rubber-composites
#10
Junyu Yang, Sameer Damle, Spandan Maiti, Sachin S Velankar
We examine the mechanics of three-layer composite films composed of an elastomeric layer sandwiched between two thin surface layers of plastic. Upon stretching and releasing such composite films, they develop a highly wrinkled surface texture. The mechanism for this texturing is that during stretching, the plastic layers yield and stretch irreversibly whereas the elastomer stretches reversibly. Thus upon releasing, the plastic layers buckle due to compressive stress imposed by the elastomer. Experiments are conducted using SEPS elastomer and 50 micron thick LLDPE plastic films...
January 5, 2017: Soft Matter
https://www.readbyqxmd.com/read/28050498/evaluation-of-low-level-laser-therapy-on-pain-perception-following-orthodontic-elastomeric-separation-a-randomized-controlled-trial
#11
Mai M E Almallah, Wael H Almahdi, Mohammad Y Hajeer
INTRODUCTION: Periodontal pain caused by elastomeric separators is a very common problem in the commencement of orthodontic treatment. Previous studies have shown good results in reducing this pain by Low Level Laser Therapy (LLLT) and different protocols of application have been suggested in the literature. AIM: This trial aimed to evaluate LLLT on managing orthodontic pain caused by elastomeric separators and to compare single versus double irradiation in possible pain reduction...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28038741/tunable-softening-and-toughening-of-individualized-cellulose-nanofibers-polyurethane-urea-elastomer-composites
#12
Minwoo Lee, Min Haeng Heo, Hwi-Hui Lee, Young-Wun Kim, Jihoon Shin
A series of elastomeric nanocomposites with superior tensile strength and extensibility, simultaneously exhibiting softening, was prepared using in situ polymerization by homogeneously dispersing TEMPO-oxidized cellulose individualized nanofibers (TOCNs) in a polyurethane urea (PUU) matrix. The structure of these PUU composites covalently cross-linked with the TOCNs was characterized. It was interesting to find that the amount and size of the hard domains in the composites gradually decreased by introducing crosslinkable TOCNs...
March 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28036169/low-initial-modulus-biodegradable-polyurethane-elastomers-for-soft-tissue-regeneration
#13
Cancan Xu, Yihui Huang, Liping Tang, Yi Hong
The mechanical match between synthetic scaffold and host tissue remains challenging in tissue regeneration. The elastic soft tissues exhibit low initial moduli with a J-shaped tensile curve. The suitable synthetic polymer scaffolds requires low initial modulus and elasticity. To achieve these requirements, random copolymers poly(δ-valerolactone-co-ε-caprolactone) (PVCL) and hydrophilic poly(ethylene glycol) (PEG) were combined into a triblock copolymer PVCL-PEG-PVCL, which was used as a soft segment to synthesize a family of biodegradable elastomeric polyurethanes with low initial moduli...
December 30, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28032047/pain-and-distress-induced-by-elastomeric-and-spring-separators-in-patients-undergoing-orthodontic-treatment
#14
Hana O Al-Balbeesi, Sahar M Bin Huraib, Nadia W AlNahas, Huda M AlKawari, Abdulrahman B Abu-Amara, Sajith Vellappally, Sukumaran Anil
AIMS AND OBJECTIVES: The objective of the present investigation is to evaluate patients' pain perception and discomfort, the duration of pain and the level of self-medication over time during tooth separation, and the effectiveness of elastomeric and spring types of orthodontic separators in Saudi population. MATERIALS AND METHODS: The study group consisted of 30 female adolescent patients who had elastomeric/spring separators as part of their orthodontic treatment...
November 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28026109/soft-elastomers-with-ionic-liquid-filled-cavities-as-strain-isolating-substrates-for-wearable-electronics
#15
Yinji Ma, Matt Pharr, Liang Wang, Jeonghyun Kim, Yuhao Liu, Yeguang Xue, Rui Ning, Xiufeng Wang, Ha Uk Chung, Xue Feng, John A Rogers, Yonggang Huang
Managing the mechanical mismatch between hard semiconductor components and soft biological tissues represents a key challenge in the development of advanced forms of wearable electronic devices. An ultralow modulus material or a liquid that surrounds the electronics and resides in a thin elastomeric shell provides a strain-isolation effect that enhances not only the wearability but also the range of stretchability in suitably designed devices. The results presented here build on these concepts by (1) replacing traditional liquids explored in the past, which have some nonnegligible vapor pressure and finite permeability through the encapsulating elastomers, with ionic liquids to eliminate any possibility for leakage or evaporation, and (2) positioning the liquid between the electronics and the skin, within an enclosed, elastomeric microfluidic space, but not in direct contact with the active elements of the system, to avoid any negative consequences on electronic performance...
December 27, 2016: Small
https://www.readbyqxmd.com/read/28024592/bi-layered-constructs-of-poly-glycerol-sebacate-%C3%AE-tricalcium-phosphate-for-bone-soft-tissue-interface-applications
#16
Atakan Tevlek, Pezhman Hosseinian, Cansel Ogutcu, Mustafa Turk, Halil Murat Aydin
This study aims to establish a facile protocol for the preparation of a bi-layered poly(glycerol-sebacate) (PGS)/β-tricalcium phosphate (β-TCP) construct and to investigate its potential for bone-soft tissue engineering applications. The layered structure was prepared by distributing the ceramic particles within a prepolymer synthesized in a microwave reactor followed by a cross-linking of the final construct in vacuum (<10mbar). The vacuum stage led to the separation of cross-linked elastomer (top) and ceramic (bottom) phases...
March 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28024367/fully-printed-stretchable-thin-film-transistors-and-integrated-logic-circuits
#17
Le Cai, Suoming Zhang, Jinshui Miao, Zhibin Yu, Chuan Wang
This paper reports intrinsically stretchable thin-film transistors (TFTs) and integrated logic circuits directly printed on elastomeric polydimethylsiloxane (PDMS) substrates. The printed devices utilize carbon nanotubes and a type of hybrid gate dielectric comprising PDMS and barium titanate (BaTiO3) nanoparticles. The BaTiO3/PDMS composite simultaneously provides high dielectric constant, superior stretchability, low leakage, as well as good printability and compatibility with the elastomeric substrate. Both TFTs and logic circuits can be stretched beyond 50% strain along either channel length or channel width directions for thousands of cycles while showing no significant degradation in electrical performance...
December 27, 2016: ACS Nano
https://www.readbyqxmd.com/read/28017585/evaluation-of-the-stromal-vascular-fraction-of-adipose-tissue%C3%A2-as-the-basis-for-a-stem-cell-based-tissue-engineered-vascular-graft
#18
Jeffrey T Krawiec, Han-Tsung Liao, LaiYee Lily Kwan, Antonio D'Amore, Justin S Weinbaum, J Peter Rubin, William R Wagner, David A Vorp
OBJECTIVE: One of the rate-limiting barriers within the field of vascular tissue engineering is the lengthy fabrication time associated with expanding appropriate cell types in culture. One particularly attractive cell type for this purpose is the adipose-derived mesenchymal stem cell (AD-MSC), which is abundant and easily harvested from liposuction procedures. Even this cell type has its drawbacks, however, including the required culture period for expansion, which could pose risks of cellular transformation or contamination...
December 22, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28009903/creep-and-fatigue-resistant-rapid-piezoresistive-responses-of-elastomeric-graphene-coated-carbon-nanotube-aerogels-over-a-wide-pressure-range
#19
Michelle N Tsui, Mohammad F Islam
Lightweight, flexible piezoresistive materials with wide operational pressure ranges are in demand for applications such as human physical activity and health monitoring, robotics, and for functional interfacing between living systems and wearable electronics. Piezoresistivity of many elastomeric foams of polymers and carbon allotropes satisfies much of the required characteristics for these applications except creep and fatigue resistance due to their viscoelasticity, critically limiting the reliability and lifetime of integrated devices...
December 23, 2016: Nanoscale
https://www.readbyqxmd.com/read/27997981/single-nucleotide-polymorphisms-and-domain-splice-variants-modulate-assembly-and-elastomeric-properties-of-human-elastin-implications-for-tissue-specificity-and-durability-of-elastic-tissue
#20
Ming Miao, Sean E Reichheld, Lisa D Muiznieks, Eva E Sitarz, Simon Sharpe, Fred W Keeley
Polymeric elastin provides the physiologically essential properties of extensibility and elastic recoil to large arteries, heart valves, lungs, skin and other tissues. Although the detailed relationship between sequence, structure and mechanical properties of elastin remains a matter of investigation, data from both the full-length monomer, tropoelastin, and smaller elastin-like polypeptides have demonstrated that variations in protein sequence can affect both polymeric assembly and tensile mechanical properties...
December 20, 2016: Biopolymers
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