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Hip fracture in adults

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https://www.readbyqxmd.com/read/28346568/impact-of-3-monthly-vitamin-d-supplementation-plus-exercise-on-survival-after-surgery-for-osteoporotic-hip-fracture-in-adult-patients-over-50-years-a-pragmatic-randomized-partially-blinded-controlled-trial
#1
A Laiz, J Malouf, A Marin, V Longobardi, J de Caso, J Farrerons, J Casademont
OBJECTIVE: To determine whether 3-monthly supplementation of an oral vitamin D widely used in Spain (calcifediol) plus daily exercise could influence survival at one and four years after surgery for osteoporotic hip fracture. DESIGN: A pragmatic, randomized, partially single-blind placebo-controlled study. SETTING: Patients admitted to a tertiary university hospital for acute hip fracture. PARTICIPANTS: 675 healthy adult patients undergoing surgery for osteoporotic hip fracture were recruited from January 2004 to December 2007...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28328823/a-case-report-of-pycnodysostosis-with-atypical-femur-fracture-diagnosed-by-next-generation-sequencing-of-candidate-genes
#2
Hyung Keun Song, Young Bae Sohn, Yong Jun Choi, Yoon-Sok Chung, Ja-Hyun Jang
RATIONALE: Pycnodysostosis is a rare autosomal recessive skeletal dysplasia characterized by short stature, craniofacial dysmorphism, acro-osteolysis, osteosclerosis, and brittle bone with poor healing. Pycnodysostosis results from the deficient activity of cathepsin K, a lysosomal cysteine protease that is encoded by CTSK. PATIENT CONCERNS: We report a Korean adult patient with pycnodysostosis and atypical femur fracture whose diagnosis was confirmed by next-generation sequencing (NGS) of candidate genes...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28326338/predictors-of-teriparatide-treatment-failure-in-patients-with-low-bone-mass
#3
Tarig Elraiyah, Adil H Ahmed, Zhen Wang, Joshua N Farr, Mohammad H Murad, Matthew T Drake
INTRODUCTION: While teriparatide is the only skeletal anabolic agent approved in the United States, treatment failure is a major concern which complicates its clinical utility. We sought to identify factors that predict response failure in patients with low bone mass. METHOD: We performed a retrospective study of adults with osteopenia or osteoporosis (T-scores < - 1.0 and - 2.5 SD below normal, respectively, at the total hip or lumbar spine) treated with teriparatide at the Mayo Clinic (Rochester, Minnesota) between November 2002-December 2012...
June 2016: Bone Reports
https://www.readbyqxmd.com/read/28325859/scoping-review-of-potential-quality-indicators-for-hip-fracture-patient-care
#4
Kristen B Pitzul, Sarah E P Munce, Laure Perrier, Lauren Beaupre, Suzanne N Morin, Rhona McGlasson, Susan B Jaglal
OBJECTIVE: The purpose of this study is to identify existing or potential quality of care indicators (ie, current indicators as well as process and outcome measures) in the acute or postacute period, or across the continuum of care for older adults with hip fracture. DESIGN: Scoping review. SETTING: All care settings. SEARCH STRATEGY: English peer-reviewed studies published from January 2000 to January 2016 were included...
March 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28324091/association-between-dabigatran-vs-warfarin-and-risk-of-osteoporotic-fractures-among-patients-with-nonvalvular-atrial-fibrillation
#5
Wallis C Y Lau, Esther W Chan, Ching-Lung Cheung, Chor Wing Sing, Kenneth K C Man, Gregory Y H Lip, Chung-Wah Siu, Joanne K Y Lam, Alan C H Lee, Ian C K Wong
Importance: The risk of osteoporotic fracture with dabigatran use in patients with nonvalvular atrial fibrillation (NVAF) is unknown. Objective: To investigate the risk of osteoporotic fracture with dabigatran vs warfarin in patients with NVAF. Design, Setting, and Participants: Retrospective cohort study using a population-wide database managed by the Hong Kong Hospital Authority. Patients newly diagnosed with NVAF from 2010 through 2014 and prescribed dabigatran or warfarin were matched by propensity score at a 1:2 ratio with follow-up until July 31, 2016...
March 21, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28321507/the-relationship-between-cumulative-lifetime-ultraviolet-radiation-exposure-bone-mineral-density-falls-risk-and-fractures-in-older-adults
#6
M J W Thompson, D A Aitken, P Otahal, J Cicolini, T M Winzenberg, G Jones
Data linking cumulative lifetime vitamin D status with skeletal outcomes are lacking. We show that increasing cumulative sun exposure was associated with higher bone mineral density in younger males and protective against fractures in females independent of current vitamin D. This supports the concept that cumulative sun exposure is an important contributor to skeletal health. INTRODUCTION: While low 25-hydroxyvitamin D levels are associated with increased fracture risk, this reflects only recent sun exposure...
March 20, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28315954/trends-in-osteoporosis-and-low-bone-mass-in-older-us-adults-2005-2006-through-2013-2014
#7
A C Looker, N Sarafrazi Isfahani, B Fan, J A Shepherd
This study examined trends in osteoporosis and low bone mass in older US adults between 2005 and 2014 using bone mineral density (BMD) data from the National Health and Nutrition Examination Survey (NHANES). Osteoporosis and low bone mass appear to have increased at the femur neck but not at the lumbar spine during this period. INTRODUCTION: Recent preliminary data from Medicare suggest that the decline in hip fracture incidence among older US adults may have plateaued in 2013-2014, but comparable data on BMD trends for this time period are currently lacking...
March 18, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28315184/epiphyseal-arterial-network-and-inferior-retinacular-artery-seem-critical-to-femoral-head-perfusion-in-adults-with-femoral-neck-fractures
#8
Dewei Zhao, Xing Qiu, Benjie Wang, Zihua Wang, Wei Wang, Jun Ouyang, Rona M Silva, Xiaotian Shi, Kai Kang, Dachuan Xu, Chuang Li, Shizhen Zhong, Yu Zhang, Kent E Pinkerton
BACKGROUND: A better understanding of the blood supply of the femoral head is essential to guide therapeutic strategies for patients with femoral neck fractures. However, because of the limitations of conventional techniques, the precise distribution and characteristics of intraosseous arteries of the femoral head are not well displayed. QUESTIONS/PURPOSES: To explore the characteristics and interconnections of the intraosseous vessel system between different areas of the femoral head and the possible blood supply compensatory mechanism after femoral neck fracture...
March 17, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28284206/racial-ethnic-differences-in-fall-prevalence-among-older-women-a-cross-sectional-survey-study
#9
Yifan Geng, Joan C Lo, Leslea Brickner, Nancy P Gordon
BACKGROUND: Falls are the leading cause of hip fracture in older women, with important public health implications. Fall risk increases with age and other clinical factors, and varies by race/ethnicity. International studies suggest that fall risk is lower in Asians, although data are limited in U.S. POPULATIONS: This study examines racial/ethnic differences in fall prevalence among older U.S. women within a large integrated healthcare delivery system. METHODS: This cross-sectional study used data from 6277 women ages 65-90 who responded to the 2008 or 2011 Kaiser Permanente Northern California Member Health Survey (KPNC-MHS)...
March 11, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28280846/obesity-type-2-diabetes-and-bone-in-adults
#10
REVIEW
Jennifer S Walsh, Tatiane Vilaca
In an increasingly obese and ageing population, type 2 diabetes (T2DM) and osteoporotic fracture are major public health concerns. Understanding how obesity and type 2 diabetes modulate fracture risk is important to identify and treat people at risk of fracture. Additionally, the study of the mechanisms of action of obesity and T2DM on bone has already offered insights that may be applicable to osteoporosis in the general population. Most available evidence indicates lower risk of proximal femur and vertebral fracture in obese adults...
March 9, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28267356/ct-of-patients-with-hip-fracture-muscle-size-and-attenuation-help-predict-mortality
#11
Robert D Boutin, Sara Bamrungchart, Cyrus P Bateni, Daniel P Beavers, Kristen M Beavers, John P Meehan, Leon Lenchik
OBJECTIVE: Our objective was to determine the association between muscle cross-sectional area and attenuation, as measured on routine CT scans, and mortality in older patients with hip fracture. MATERIALS AND METHODS: A retrospective 10-year study of patients with hip fracture was conducted with the following inclusion criteria: age 65 years or older, first-time hip fracture treated with surgery, and CT of the chest, abdomen, or pelvis. This yielded 274 patients (70...
March 7, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28263371/association-between-preoperative-malnutrition-and-postoperative-delirium-after-hip-fracture-surgery-in-older-adults
#12
Paolo Mazzola, Libby Ward, Sara Zazzetta, Valentina Broggini, Alessandra Anzuini, Breanna Valcarcel, Justin S Brathwaite, Giulio M Pasinetti, Giuseppe Bellelli, Giorgio Annoni
OBJECTIVES: To determine whether poor nutritional status can predict postoperative delirium in elderly adults undergoing hip fracture surgery. DESIGN: Prospective observational cohort study. SETTING: Italian orthogeriatric unit. PARTICIPANTS: Individuals aged 70 and older (mean age 84.0 ± 6.6, 74.5% female) consecutively admitted for surgical repair of a proximal femur fracture between September 2012 and April 2016 (N = 415)...
March 6, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28263366/ageism-in-studies-on-the-management-of-osteoporosis
#13
Caoimhe McGarvey, Tara Coughlan, Desmond O'Neill
OBJECTIVES: To review the literature to assess whether the fact that osteoporosis is chiefly considered a disease of the older population was reflected in research in the area of the management of osteoporosis and to determine the extent of ageism in studies on the management of osteoporosis. DESIGN: Review. SETTING: All randomized control trials on the management of osteoporosis entered in the Cochrane Library Database that reported mean age were included...
March 6, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28263244/a-cadaveric-study-of-ultrasound-guided-subpectineal-injectate-spread-around-the-obturator-nerve-and-its-hip-articular-branches
#14
Thomas D Nielsen, Bernhard Moriggl, Kjeld Søballe, Jens A Kolsen-Petersen, Jens Børglum, Thomas Fichtner Bendtsen
BACKGROUND AND OBJECTIVES: The femoral and obturator nerves are assumed to account for the primary nociceptive innervation of the hip joint capsule. The fascia iliaca compartment block and the so-called 3-in-1-block have been used in patients with hip fracture based on a presumption that local anesthetic spreads to anesthetize both the femoral and the obturator nerves. Evidence demonstrates that this presumption is unfounded, and knowledge about the analgesic effect of obturator nerve blockade in hip fracture patients presurgically is thus nonexistent...
March 3, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/28260154/the-cost-and-mortality-of-hip-fractures-in-centenarians
#15
J Moore, O Carmody, B Carey, J A Harty, D Reidy
BACKGROUND: Centenarians are the fastest rising age group in Ireland. Hip fractures most commonly affect older adults and are associated with significant morbidity and mortality, as well as the financial cost of healthcare resources. Despite this, very little is known regarding hip fractures in centenarians. The aim of this study was to investigate our experience with hip fractures in this group and to record the cost of treating these fractures to identify both the social and economic impact these injuries impose on the health system...
March 4, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28252470/asymmetries-identified-in-sit-to-stand-task-explain-physical-function-after-hip-fracture
#16
Robert A Briggs, Jeff R Houck, Micah J Drummond, Julie M Fritz, Paul C LaStayo, Robin L Marcus
BACKGROUND: Several known demographic and functional characteristics combine to predict physical function after hip fracture. Long-term weight-bearing asymmetries, evident during functional movements after hip fracture, contribute to limited mobility and large asymmetries in muscle function are linked to a high rate of injurious falls. Although postfracture mobility is commonly measured as whole body movement, a force-plate imbedded chair can identify individual limb contributions to an important task like moving from a sitting to standing position...
March 1, 2017: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/28251687/fracture-risk-after-bariatric-surgery-roux-en-y-gastric-bypass-versus-adjustable-gastric-banding
#17
Elaine W Yu, Moa P Lee, Joan E Landon, Katherine G Lindeman, Seoyoung C Kim
The long-term consequences of bariatric surgery on fracture risk are unclear but are likely to vary by procedure type. In physiologic studies, Roux-en-Y gastric bypass (RYGB) and adjustable gastric banding (AGB) have differential effects on rates of bone loss. Therefore, our objective was to compare fracture risk in obese adults after RYGB and AGB procedures. Using claims data from a US commercial health plan, we analyzed rates of nonvertebral fractures within a propensity score-matched cohort (n = 15,032) of morbidly obese adults who received either RYGB or AGB surgery between 2005 and 2013...
March 2, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28249677/factors-influencing-patient-experience-and-satisfaction-following-surgical-management-of-ankle-fractures
#18
Fiona Ashton, Khalid Hamid, Shazali Sulieman, William Eardley, Paul Baker
BACKGROUND: Patient feedback is increasingly important to inform and develop effective healthcare within the United Kingdom. In order to optimise patient experience of ankle fracture care in our unit, we sought to identify elements of practice associated with poor patient experience and low levels of satisfaction. METHODS: Adult patients with closed ankle fractures requiring fixation over a ten month period were prospectively identified. Prior to discharge all patients completed the Picker Patient Experience Questionnaire (PPE-15), satisfaction visual analogue scale (VAS: 0-10) and a demographic questionnaire...
February 22, 2017: Injury
https://www.readbyqxmd.com/read/28246930/association-of-plasma-sdf-1-with-bone-mineral-density-body-composition-and-hip-fractures-in-older-adults-the-cardiovascular-health-study
#19
Laura D Carbone, Petra Bůžková, Howard A Fink, John A Robbins, Monique Bethel, Mark W Hamrick, William D Hill
Aging is associated with an increase in circulating inflammatory factors. One, the cytokine stromal cell-derived factor 1 (SDF-1 or CXCL12), is critical to stem cell mobilization, migration, and homing as well as to bone marrow stem cell (BMSC), osteoblast, and osteoclast function. SDF-1 has pleiotropic roles in bone formation and BMSC differentiation into osteoblasts/osteocytes, and in osteoprogenitor cell survival. The objective of this study was to examine the association of plasma SDF-1 in participants in the cardiovascular health study (CHS) with bone mineral density (BMD), body composition, and incident hip fractures...
February 28, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28238673/bisphosphonate-use-after-hip-fracture-in-older-adults-a%C3%A2-nationwide-retrospective-cohort-study
#20
Peter Nordström, Annika Toots, Yngve Gustafson, Karl-Göran Thorngren, Ami Hommel, Anna Nordström
OBJECTIVES: The aim of this study was to investigate the association between bisphosphonate use and the risk of new fracture in a nationwide cohort of individuals with previous hip fractures, with emphasis on individuals above 80 years of age. DESIGN, SETTING, AND PARTICIPANTS: From a nationwide cohort with hip fracture (2006-2012) (n = 93, 601), each individual prescribed bisphosphonates after hip fracture (n = 5845) was matched with up to three individuals not prescribed bisphosphonates, resulting in a cohort of 21,363 individuals...
February 23, 2017: Journal of the American Medical Directors Association
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