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https://www.readbyqxmd.com/read/28098916/depression-and-suicidal-ideation-among-canadians-aged-15-to-24
#1
Leanne Findlay
BACKGROUND: Among Canadians aged 15 to 24, the rate of depression is higher than at any other age, and suicide is the second leading cause of death. The current study provides detailed information about depression and suicidal ideation among young Canadians, including their use of mental health support. DATA AND METHODS: Data from the 2012 Canadian Community Health Survey-Mental Health (CCHS-MH) were used to describe rates and experiences of depression and suicidal ideation among Canadians aged 15 to 24, including psychosocial characteristics of those who had depression or reported suicidal thoughts...
January 18, 2017: Health Reports
https://www.readbyqxmd.com/read/28070480/central-congenital-hypoventilation-syndrome-associated-with-hypoglycemia-and-seizure
#2
Emily Hopkins, James Stark, Ricardo A Mosquera
Central Congenital Hypoventilation Syndrome (CCHS) is a rare diagnosis that presents with various forms of autonomic dysfunction. The disease is characterized by reduced chemoreflexes and severe hypoventilation during sleep. Several case reports have noted that patients with CCHS have been found to suffer from hypoglycemic episodes, which frequently present as a seizure. In this report, we will review previous case presentations to alert the physicians about this association with hypoglycemic episodes. Early treatment and monitoring of hypoglycemia will prevent further complications for these populations...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28063943/genetic-variation-in-wrn-and-ischemic-stroke-general-population-studies-and-meta-analyses
#3
Mette Christoffersen, Ruth Frikke-Schmidt, Børge G Nordestgaard, Anne Tybjærg-Hansen
BACKGROUND: Werner syndrome, a premature genetic aging syndrome, shares many clinical features reminiscent of normal physiological aging, and ischemic vascular disease is a frequent cause of death. We tested the hypothesis that genetic variation in the WRN gene was associated with risk of ischemic vascular disease in the general population. METHODS: We included 58,284 participants from two general population cohorts, the Copenhagen City Heart Study(CCHS) and the Copenhagen General Population Study(CGPS)...
January 4, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28054205/the-social-and-spatial-patterning-of-life-stress-among-immigrants-in-canada
#4
Lu Wang, Elmer Lara Palacios
While much literature has examined immigrants' health in Canada, less attention has focused specifically on the life stress, an important yet understudied post-migration challenge which may lead to poor coping strategies and negative health consequences. For this study, the pooled 2009-2014 Canadian Community Health Survey (CCHS) was analyzed, using multilevel logistic regression to examine the compositional effects (at an individual level) and areal effects (at a CMA/CA level) on reported high life stress...
January 4, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28018870/cancer-incidence-attributable-to-tobacco-in-alberta-canada-in-2012
#5
Abbey E Poirier, Anne Grundy, Farah Khandwala, Sierra Tamminen, Christine M Friedenreich, Darren R Brenner
BACKGROUND: Strong and consistent epidemiologic evidence shows that tobacco smoking causes cancers at various sites. The purpose of this study was to quantify the proportion and total number of site-specific cancers in Alberta attributable to tobacco exposure. METHODS: The proportion of incident cancer cases attributable to active and passive tobacco exposure in Alberta was estimated with population attributable risks. Data from the Canadian Community Health Survey (CCHS) for 2000-2007 were used to estimate prevalence of active (current or former smoker) and passive (second-hand smoke) tobacco exposure in Alberta...
October 2016: CMAJ Open
https://www.readbyqxmd.com/read/28002578/linking-the-canadian-community-health-survey-and-the-canadian-mortality-database-an-enhanced-data-source-for-the-study-of-mortality
#6
Claudia Sanmartin, Yves Decady, Richard Trudeau, Abel Dasylva, Michael Tjepkema, Philippe Finès, Rick Burnett, Nancy Ross, Douglas G Manuel
BACKGROUND: This study summarizes the linkage of the Canadian Community Health Survey (CCHS) and the Canadian Mortality Database (CMDB), which was performed to examine relationships between social determinants, health behaviours and mortality in the household population. DATA AND METHODS: The 2000/2001-to-2011 Canadian Community Health Surveys were linked to the 2000-to-2011 CMDB using probabilistic methods based on common identifiers (names, date of birth, postal code and sex) for eligible respondents (85%; n = 614,774)...
December 21, 2016: Health Reports
https://www.readbyqxmd.com/read/27991658/untangling-the-association-between-migraine-pain-and-anxiety-examining-migraine-and-generalized-anxiety-disorders-in-a-canadian-population-based-study
#7
Esme Fuller-Thomson, Janany Jayanthikumar, Senyo K Agbeyaka
OBJECTIVE: The aims of this study were to investigate: (1) the prevalence and unadjusted and adjusted odds of 12-month generalized anxiety disorder (GAD) among adults with migraine in comparison to those without migraine; (2) If debilitating pain and/or limitations in instrumental activities of daily living (IADLs) are mediators of the migraine-GAD association; and (3) Factors associated with past year GAD among adults with migraine. METHODS: Secondary data analysis of the nationally representative 2012 Canadian Community Health Survey-Mental Health (CCHS-MS), a population-based survey of community dwellers with a response rate of 68...
December 19, 2016: Headache
https://www.readbyqxmd.com/read/27918326/anesthetic-considerations-for-patients-with-congenital-central-hypoventilation-syndrome-a-systematic-review-of-the-literature
#8
Saptashree M Basu, Frances F Chung, Shireen F AbdelHakim, Jean Wong
Congenital central hypoventilation syndrome (CCHS) is a form of sleep-disordered breathing characterized by a diminished drive to breathe during sleep, despite progressive hypercapnia and hypoxia. The condition results from mutations in the paired-like homeobox 2B (PHOX2B) gene. The aim of this review was to conduct a systematic search of the current data on CCHS as it relates to perioperative considerations and to discuss the classification, prevalence, pathophysiology, presentation, genetics, and management of the condition...
January 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27904233/examining-the-supply-of-and-demand-for-physiotherapy-in-saskatchewan-the-relationship-between-where-physiotherapists-work-and-population-health-need
#9
Brighid McFadden, Kendra Jones McGrath, Teghan Lowe, Carla Thiessen, Steven Irinici, Tayyab Shah, Stephan Milosavljevic, Brenna Bath
Purpose: This research examined the association between the distribution of physiotherapists in Saskatchewan relative to population health characteristics and self-reported physiotherapy use. Methods: Using a cross-sectional design, de-identified data were collected from the 2013 Saskatchewan College of Physical Therapy membership renewals (n=643), and Saskatchewan population health characteristics data were obtained from the 2009-2012 Canadian Community Health Surveys (CCHSs). Age- and sex-adjusted proportions of selected population health characteristics were calculated and stratified by health region and rural-urban location; both were determined, for physiotherapists and CCHS participants, using postal codes...
2016: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/27902568/health-utilities-in-people-with-chronic-pain-using-a-population-level-survey-and-linked-health-care-administrative-data
#10
Mary-Ellen Hogan, Anna Taddio, Joel Katz, Vibhuti Shah, Murray Krahn
Health utilities are a preference-based measure of health-related quality of life that facilitates comparison of disease burden across conditions. We estimated utilities using a population-based, matched sample of adolescents and adults with and without chronic pain, controlling for comorbidity. Ontarians aged ≥12 years with and without chronic pain were identified from the Canadian Community Health Survey (CCHS) 2000-2001 and 2009-2010 and linked to their provincial health care administrative data. Individuals with chronic pain were matched to those without using age, sex, survey year, and a propensity score for having chronic pain estimated from a rurality index, income quintile, and comorbidity...
November 24, 2016: Pain
https://www.readbyqxmd.com/read/27882860/is-child-sexual-abuse-declining-in-canada-results-from-nationally-representative-retrospective-surveys
#11
M Shields, L Tonmyr, W Hovdestad
INTRODUCTION: Numerous data sources suggest a decline in child sexual abuse (CSA) in the United States since the early 1990s. Some evidence also indicates that an earlier period of higher CSA incidence began following World War II. This study examines prevalence estimates of sexual abuse reported retrospectively as having occurred in childhood (ChSA) in two nationally representative surveys of the Canadian population. METHODS: Data are from 13 931 respondents aged 18 to 76 years from the 2004/2005 Canadian Gender, Alcohol, and Culture: An International Study (GENACIS), and from 22 169 household residents aged 18 years or older who participated in the 2012 Canadian Community Health Survey-Mental Health (CCHS-MH)...
November 2016: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/27849313/hearing-difficulties-and-feelings-of-social-isolation-among-canadians-aged-45-or-older
#12
Pamela L Ramage-Morin
BACKGROUND: Social isolation is associated with reduced health-related quality of life, increased morbidity, and mortality. Social isolation can be a concern for older Canadians, especially those with conditions that interfere with making and maintaining social connections. DATA AND METHODS: The 2008/2009 Canadian Community Health Survey-Healthy Aging (CCHS-HA) collected data from a population-based sample of Canadians aged 45 or older living in private households...
16, 2016: Health Reports
https://www.readbyqxmd.com/read/27849044/colon-cancer-subtypes-concordance-effect-on-survival-and-selection-of-the-most-representative-preclinical-models
#13
Zsófia Sztupinszki, Balázs Győrffy
Multiple gene-expression-based subtypes have been proposed for the molecular subdivision of colon cancer in the last decade. We aimed to cross-validate these classifiers to explore their concordance and their power to predict survival. A gene-chip-based database comprising 2,166 samples from 12 independent datasets was set up. A total of 22 different molecular subtypes were re-trained including the CCHS, CIN25, CMS, ColoGuideEx, ColoGuidePro, CRCassigner, MDA114, Meta163, ODXcolon, Oncodefender, TCA19, and V7RHS classifiers as well as subtypes established by Budinska, Chang, DeSousa, Marisa, Merlos, Popovici, Schetter, Yuen, and Watanabe (first authors)...
November 16, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27834630/migraine-and-mental-health-in-a-population-based-sample-of-adolescents
#14
Serena L Orr, Beth K Potter, Jinhui Ma, Ian Colman
OBJECTIVE: To explore the relationship between migraine and anxiety disorders, mood disorders and perceived mental health in a population-based sample of adolescents. METHODS: The Canadian Community Health Survey (CCHS) is a cross-sectional health survey sampling a nationally representative group of Canadians. In this observational study, data on all 61,375 participants aged 12-19 years from six survey cycles were analyzed. The relationships between self-reported migraine, perceived mental health, and mood/anxiety disorders were modeled using univariate and multivariate logistic regression...
January 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/27831480/impact-of-the-2008-global-financial-crisis-on-the-health-of-canadians-repeated-cross-sectional-analysis-of-the-canadian-community-health-survey-2007-2013
#15
Sabrina Nour, Ronald Labonté, Christina Bancej
BACKGROUND: Despite a clear impact on the Canadian economy, little is known about the subsequent health impacts of the 2008 global financial crisis (GFC) in this country. This study fills this gap in knowledge by conducting a repeated cross-sectional analysis of the Canadian Community Health Survey (CCHS). METHODS: Data from 7 cycles (2007-2013) of the CCHS were combined to form a large data set representative of the Canadian working-age population (15-64 years) residing in 1 of 10 provinces...
November 9, 2016: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/27763841/unmet-health-care-needs-among-sex-workers-in-five-census-metropolitan-areas-of-canada
#16
Cecilia Benoit, Nadia Ouellet, Mikael Jansson
OBJECTIVES: This paper examines unmet health care needs in one of Canada's most hard-to-reach populations, adult sex workers, and investigates whether their reasons for not accessing health care are different from those of other Canadians. METHODS: Data gathered in 2012-2013 from sex workers aged 19 and over (n = 209) in five Canadian census metropolitan areas (CMAs) were analyzed to estimate the perceived health, health care access and level of unmet health care needs of sex workers, and their principal reasons for not accessing health care...
October 20, 2016: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/27702639/the-influence-of-walkability-on-broader-mobility-for-canadian-middle-aged-and-older-adults-an-examination-of-walk-score%C3%A2-and-the-mobility-over-varied-environments-scale-moves
#17
Jana A Hirsch, Meghan Winters, Philippa J Clarke, Nathalie Ste-Marie, Heather A McKay
Neighborhood built environments may play an important role in shaping mobility and subsequent health outcomes. However, little work includes broader mobility considerations such as cognitive ability to be mobile, social connections with community, or transportation choices. We used a population-based sample of Canadian middle aged and older adults (aged 45 and older) from the Canadian Community Health Survey-Healthy Aging (CCHS-HA, 2008-2009) to create a holistic mobility measure: Mobility over Varied Environments Scale (MOVES)...
October 1, 2016: Preventive Medicine
https://www.readbyqxmd.com/read/27673423/congenital-central-hypoventilation-syndrome-a-bedside-to-bench-success-story-for-advancing-early-diagnosis-and-treatment-and-improved-survival-and-quality-of-life
#18
REVIEW
Debra E Weese-Mayer, Casey M Rand, Amy Zhou, Michael S Carroll, Carl E Hunt
The "bedside-to-bench" Congenital Central Hypoventilation Syndrome (CCHS) research journey has led to increased phenotypic-genotypic knowledge regarding autonomic nervous system (ANS) regulation, and improved clinical outcomes. CCHS is a neurocristopathy characterized by hypoventilation and ANS dysregulation. Initially described in 1970, timely diagnosis and treatment remained problematic until the first large cohort report (1992), delineating clinical presentation and treatment options. A central role of ANS dysregulation (2001) emerged, precipitating evaluation of genes critical to ANS development, and subsequent 2003 identification of Paired-Like Homeobox 2B (PHOX2B) as the disease-defining gene for CCHS...
November 2, 2016: Pediatric Research
https://www.readbyqxmd.com/read/27666512/productivity-costs-of-work-loss-associated-with-osteoarthritis-in-canada-from-2010-to-2031
#19
B Sharif, R Garner, D Hennessy, C Sanmartin, W M Flanagan, D A Marshall
OBJECTIVE: To estimate and project the productivity costs of work loss (PCWL) associated with osteoarthritis (OA) in Canada using a population-based health microsimulation model (POHEM). DESIGN: We integrated an employment module based on 2006 Canadian Census into the previously developed microsimulation model of OA. The Canadian Community Health Survey (CCHS) Cycle 2.1 with an OA sample aged 25-64 (n = 7067) was used to calibrate the results of the employment module and to estimate the fraction of non-employment associated with OA...
September 23, 2016: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/27651445/scarb1-gene-variants-are-associated-with-the-phenotype-of-combined-high-hdl-c-and-high-lp-a
#20
Xiaoping Yang, Amar Sethi, Lisa R Yanek, Cathy Knapper, Børge G Nordestgaard, Anne Tybjærg-Hansen, Diane M Becker, Rasika A Mathias, Alan T Remaley, Lewis C Becker
BACKGROUND: -Scavenger receptor class B type 1 (SR-B1), encoded by the gene SCARB1, is a lipoprotein receptor which binds both high density and low density lipoproteins (HDL and LDLs). We reported that SR-B1 is also a receptor for lipoprotein (a) (Lp(a)), mediating cellular uptake of Lp(a) in vitro and promoting clearance of Lp(a) in vivo. Although genetic variants in SCARB1 are associated with variations in HDL level, no SCARB1 variants affecting Lp(a) have been reported. METHODS AND RESULTS: -In an index subject with high levels of HDL-C and Lp(a), SCARB1 was sequenced and demonstrated a missense mutation resulting in an S129L substitution in exon 3...
September 20, 2016: Circulation. Cardiovascular Genetics
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