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Fat soluble vitamins

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https://www.readbyqxmd.com/read/27875503/influence-of-partial-external-biliary-diversion-on-the-lipid-profile-in-children-with-progressive-familial-intrahepatic-cholestasis
#1
Irena Jankowska, Piotr Czubkowski, Aldona Wierzbicka, Joanna Pawłowska, Piotr Kaliciński, Piotr Socha
OBJECTIVES: The concentration of bile acids is highly increased in progressive familial intrahepatic cholestasis (PFIC). Bile acids are the end products of cholesterol metabolism, and aid in the absorption of fat-soluble vitamins and dietary fat. The aim of our study was to investigate lipid metabolism in patients with PFIC with focus on the effect of partial external biliary diversion (PEBD). METHODS: In 26 patients with PFIC, who underwent PEBD surgery at the median age of 2...
December 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27865346/maternal-fat-soluble-vitamins-brain-development-and-regulation-of-feeding-behavior-an-overview-of-research
#2
REVIEW
Diana Sánchez-Hernández, G Harvey Anderson, Abraham N Poon, Emanuela Pannia, Clara E Cho, Pedro S P Huot, Ruslan Kubant
Recent research shows a link between vitamin intake during pregnancy and offspring health. Inadequate intakes of water-soluble vitamins during pregnancy lead to obesity and characteristics of the metabolic syndrome, concurrent with altered developments in food intake regulatory pathways. Few studies, however, have reported on the effects of fat-soluble vitamins (A, D, E, and K) on the development of food intake regulatory pathways. The majority of studies to date have focused on associations between inadequate and high intakes of folic acid and vitamin D and neurocognitive development of the offspring...
October 2016: Nutrition Research
https://www.readbyqxmd.com/read/27862054/determination-of-target-fat-soluble-micronutrients-in-rainbow-trout-s-muscle-and-liver-tissues-by-liquid-chromatography-with-diode-array-tandem-mass-spectrometry-detection
#3
Virginia Pérez Fernández, Salvatore Ventura, Pierpaolo Tomai, Roberta Curini, Alessandra Gentili
This paper describes an analytical approach, based on liquid chromatography-diode array detection-tandem mass spectrometry (LC-DAD-MS/MS), for characterizing the fat-soluble micronutrient fraction in rainbow trout (Oncorhynchus mykiss). Two different procedures were applied to isolate the analytes from liver and muscle tissue: overnight cold saponification to hydrolyze bound forms and to simplify the analysis; matrix solid phase dispersion (MSPD) to avoid artifacts and to maintain unaltered the naturally occurring forms...
November 12, 2016: Electrophoresis
https://www.readbyqxmd.com/read/27849624/efficacy-of-micellized-vs-fat-soluble-vitamin-d3-supplementation-in-healthy-school-children-from-northern-india
#4
Raman K Marwaha, Vamsi K Yenamandra, Mohammed Asraf Ganie, Gomathy Sethuraman, Vishnubhatla Sreenivas, Lakshmy Ramakrishnan, Sathish K Mathur, Vinod K Sharma, Ambrish Mithal
BACKGROUND: Vitamin D deficiency is a widely recognized public health problem. Efficacy of a recently developed micellized form of vitamin D3 has not been studied. Hence, we undertook this study to compare its efficacy with the conventionally used fat-soluble vitamin D3. METHODS: In this open-labeled nonrandomized pilot study, we recruited 180 healthy children, aged 13-14 years in two groups and supplemented Group A (60 children) with 60,000 IU of fat-soluble vitamin D3/month with milk and Group B (120 children) with 60,000 IU/month of water miscible vitamin D3 under supervision for 6 months...
December 1, 2016: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/27833859/associations-of-25-hydroxyvitamin-d-with-markers-of-inflammation-insulin-resistance-and-obesity-in-black-and-white-community-dwelling-adults
#5
Jennifer L Jackson, Suzanne E Judd, Bhupesh Panwar, Virginia J Howard, Virginia G Wadley, Nancy S Jenny, Orlando M Gutiérrez
AIMS: Vitamin D is a fat-soluble vitamin classically known for its role in calcium absorption and bone health. Growing evidence indicates that vitamin D deficiency may be associated with inflammation, insulin resistance, and obesity. However, prior studies examining the association of vitamin D with metabolic risk factors had relatively low representation of individuals of black race, limiting their ability to characterize associations of vitamin D and parameters of metabolic health in black vs...
September 2016: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/27816611/vitamin-e-emerging-aspects-and-new-directions
#6
REVIEW
Francesco Galli, Angelo Azzi, Marc Birringer, Joan M Cook-Mills, Manfred Eggersdorfer, Jan Frank, Gabriele Cruciani, Stefan Lorkowski, Nesrin Kartal Özer
The discovery of vitamin E will have its 100th anniversary in 2022, but we still have more questions than answers regarding the biological functions and the essentiality of vitamin E for human health. Discovered as a factor essential for rat fertility and soon after characterized for its properties of fat-soluble antioxidant, vitamin E was identified to have signaling and gene regulation effects in the 1980s. In the same years the cytochrome P-450 dependent metabolism of vitamin E was characterized and a first series of studies on short-chain carboxyethyl metabolites in the 1990s paved the way to the hypothesis of a biological role for this metabolism alternative to vitamin E catabolism...
November 2, 2016: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/27793606/diet-as-a-trigger-or-therapy-for-inflammatory-bowel-diseases
#7
James D Lewis, Maria T Abreu
The most common question asked by patients with inflammatory bowel disease is "doctor what should I eat?" Findings from epidemiology studies indicate that diets high in animal fat and low in fruits and vegetables are the most common pattern associated with an increased risk of IBD. Low levels of vitamin D also appear to be a risk factor for IBD. In murine models, diets high in fat, especially saturated animal fats, also increase inflammation, whereas supplementation with omega 3 long-chain fatty acids protect against intestinal inflammation...
October 25, 2016: Gastroenterology
https://www.readbyqxmd.com/read/27792188/the-impact-of-vitamin-e-and-other-fat-soluble-vitamins-on-alzheimer%C3%A2-s-disease
#8
REVIEW
Marcus O W Grimm, Janine Mett, Tobias Hartmann
Alzheimer's disease (AD) is the most common cause of dementia in the elderly population, currently affecting 46 million people worldwide. Histopathologically, the disease is characterized by the occurrence of extracellular amyloid plaques composed of aggregated amyloid-β (Aβ) peptides and intracellular neurofibrillary tangles containing the microtubule-associated protein tau. Aβ peptides are derived from the sequential processing of the amyloid precursor protein (APP) by enzymes called secretases, which are strongly influenced by the lipid environment...
October 26, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27786545/vitamin-d-levels-in-children-affected-by-vernal-keratoconjuctivitis
#9
Anna Maria Zicari, Arianna Cafarotti, Francesca Occasi, Valeria Lollobrigida, Marcella Nebbioso, Irene Pecorella, Giovanna De Castro, Alberto Spalice, Lorenzo Loffredo, Maria Pia Villa, Marzia Duse
BACKGROUND: Vernal keratoconjunctivitis (VKC) is a chronic and often severe bilateral conjunctivitis. VKC etiology remains still unclear although endocrine, genetic, neurogenic and environmental factors have been implied. Vitamin D is a fat-soluble prohormone whose main function is the regulation of calcium and phosphate metabolism. The aim of this study was to evaluate serum vitamin D in children affected by VKC compared to the healthy children and investigate the relationship between its levels and disease severity...
October 27, 2016: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/27769076/the-role-of-dietary-supplements-in-inflammatory-bowel-disease-a-systematic-review
#10
Roberta E Rossi, Tara Whyand, Charles D Murray, Mark I Hamilton, Dario Conte, Martyn E Caplin
Inflammatory bowel diseases (IBD) are chronic immune disorders of unclear aetiology. Dietary deficiencies may be a potential pathogenic factor in their development. Patients often take food supplements without knowledge of any evidence base. We have therefore assessed the evidence for food supplementation in the management of IBD. A PubMed search was performed for the terms Inflammatory bowel disease; nutritional deficiencies; dietary supplements; curcumin; green tea; vitamin D/other vitamins; folic acid; iron; zinc; probiotics; andrographis paniculata; and boswellia serrate...
December 2016: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27756413/fat-and-vitamin-intakes-during-pregnancy-have-stronger-relations-with-a-pro-inflammatory-maternal-microbiota-than-does-carbohydrate-intake
#11
Siddhartha Mandal, Keith M Godfrey, Daniel McDonald, Will V Treuren, Jørgen V Bjørnholt, Tore Midtvedt, Birgitte Moen, Knut Rudi, Rob Knight, Anne Lise Brantsæter, Shyamal D Peddada, Merete Eggesbø
BACKGROUND: Although diet is known to have a major modulatory influence on gut microbiota, knowledge of the specific roles of particular vitamins, minerals, and other nutrients is limited. Modulation of the composition of the microbiota in pregnant women is especially important as maternal microbes are transferred during delivery and initiate the colonization process in the infant. We studied the associations between intake of specific dietary nutrients during pregnancy and gut microbiota composition...
October 19, 2016: Microbiome
https://www.readbyqxmd.com/read/27754400/development-of-an-advanced-hplc-ms-ms-method-for-the-determination-of-carotenoids-and-fat-soluble-vitamins-in-human-plasma
#12
Barbora Hrvolová, Miriam Martínez-Huélamo, Mariel Colmán-Martínez, Sara Hurtado-Barroso, Rosa Maria Lamuela-Raventós, Jiří Kalina
The concentration of carotenoids and fat-soluble vitamins in human plasma may play a significant role in numerous chronic diseases such as age-related macular degeneration and some types of cancer. Although these compounds are of utmost interest for human health, methods for their simultaneous determination are scarce. A new high pressure liquid chromatography (HPLC)-tandem mass spectrometry (MS/MS) method for the quantification of selected carotenoids and fat-soluble vitamins in human plasma was developed, validated, and then applied in a pilot dietary intervention study with healthy volunteers...
October 14, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27749919/effects-of-ready-to-eat-cereals-on-key-nutritional-and-health-outcomes-a-systematic-review
#13
Marion G Priebe, Jolene R McMonagle
BACKGROUND: In many countries breakfast cereals are an important component of breakfast. This systematic review assesses the contribution of consumption of ready-to eat cereal (RTEC) to the recommended nutrient intake. Furthermore, the effects of RTEC consumption on key health parameters are investigated as well as health promoting properties of RTEC. METHOD: The Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and CINAHL have been searched up till 16th of June 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27744736/bone-mineral-density-and-fat-soluble-vitamin-status-in-adults-with-cystic-fibrosis-undergoing-lung-transplantation-a-pilot-study
#14
Grace Hubert, Theresa Tam Chung, Connie Prosser, Dale Lien, Justin Weinkauf, Neil Brown, Marianne Goodvin, Kathy Jackson, Joan Tabak, Josette Salgado, Abeer Salman Alzaben, Diana R Mager
PURPOSE: Patients with cystic fibrosis (CF) often experience low bone mineral density (BMD) pre- and post-lung transplantation (LTX). The study purpose was to describe BMD and micronutrient status in adults with CF pre- and post-LTX. METHODS: Twelve patients with CF (29 ± 8 years) were recruited from the CF clinic at the University of Alberta Lung Transplant Program. BMD and vitamins A, D, E, K status, and parathyroid hormone were measured pre- and post-LTX. RESULTS: No significant differences pre- and post-LTX were observed at the different bone sites measured (lumber-spine, femoral-neck (FN), hip, and femoral-trochlea) (P > 0...
July 19, 2016: Canadian Journal of Dietetic Practice and Research
https://www.readbyqxmd.com/read/27725362/a-review-of-extraction-techniques-for-avocado-oil
#15
Xiaoli Qin, Jinfeng Zhong
Avocado fruit is rich in monounsaturated fat and contains relatively high level of important lipid-soluble compounds such as vitamin E, β-sitosterol and carotenoids. The consumption of avocado fruit is highly related to its potential benefits. However, with the increase of avocado production, short time of maturation and easy oxidation of avocado fruit are the main problem for producers. The production of oil from avocado fruit, thus, is highly promoted. This paper discusses the effects of different extraction methods on chemical composition and yield of oils from avocado fruits...
September 30, 2016: Journal of Oleo Science
https://www.readbyqxmd.com/read/27715010/combined-measurement-of-6-fat-soluble-vitamins-and-26-water-soluble-functional-vitamin-markers-and-amino-acids-in-50-%C3%A2%C2%B5l-of-serum-or-plasma-by-high-throughput-mass-spectrometry
#16
Øivind Midttun, Adrian McCann, Ove Aarseth, Marit Krokeide, Gry Kvalheim, Klaus Meyer, Per Magne Ueland
Targeted metabolic profiling characterized by complementary platforms, multiplexing and low volume consumption are increasingly used for studies using biobank material. Using liquid-liquid extraction, we developed a sample workup suitable for quantification of 6 fat- and 26 water-soluble biomarkers. 50μL of serum/plasma was mixed with dithioerythritol, ethanol and isooctane/chloroform. The organic layer was used for analysis of the fat-soluble vitamins all-trans retinol (A), 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, α-tocopherol (E), γ-tocopherol (E) and phylloquinone (K1) by LC-MS/MS...
October 7, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/27708533/rice-bran-dietary-supplementation-improves-neurological-symptoms-and-loss-of-purkinje-cells-in-vitamin-e-deficient-mice
#17
Toru Takahashi, Kazuhiro Nakaso, Yosuke Horikoshi, Takehiko Hanaki, Miho Yamakawa, Masato Nakasone, Yoshinori Kitagawa, Taisuke Koike, Tatsuya Matsura
BACKGROUND: Vitamin E (VE, α-tocopherol) is a fat-soluble vitamin and is well known as an antioxidant. A deficiency in VE induces oxidative stress in the brain and causes motor and memory dysfunction. The consumption of a VE-rich diet has been given much attention in recent years, in regards to anti-aging and the prevention of age-related neuronal disorders. METHODS: A VE-deficient mouse model was prepared by feeding the animals a diet lacking VE. In addition, to evaluate the effect of VE-containing rice bran (RB) on VE deficiency, a diet including RB was also provided...
September 2016: Yonago Acta Medica
https://www.readbyqxmd.com/read/27690005/oral-supplementation-with-a-special-additive-of-retinyl-palmitate-and-alpha-tocopherol-reduces-growth-retardation-in-young-pancreatic-duct-ligated-pigs-used-as-a-model-for-children-suffering-from-exocrine-pancreatic-insufficiency
#18
Anne Mößeler, Marion Schmicke, Martin Höltershinken, Martin Beyerbach, Josef Kamphues
Pancreatic exocrine insufficiency (PEI) is a disease of diverse aetiology-e.g., majority of patients suffering from cystic fibrosis (CF) show PEI congenitally. Malnutrition and malabsorption of nutrients impair growth and nutritional status. As reduced fat digestion leads to a deficiency of fat-soluble vitamins the supplementation is standard, but absorption is a critical point in PEI-patients. The pancreatic duct ligated (PL) pig is an established model for PEI in humans and has been proven to be a suitable model to compare different vitamin additives for supplementation...
2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27683792/impact-of-vitamin-d-and-calcium-deficiency-in-the-bones-of-patients-undergoing-bariatric-surgery-a-systematic-review
#19
Jefry Alberto Vargas Cabral, Gabriela Pereira de Souza, Juliana de Almeida Nascimento, Luis Fernando Simoneti, Carolina Marchese, Silvia Helena de Carvalho Sales-Peres
Introduction: Bariatric surgery is considered the most effective tool in the control and treatment of severe obesity, but patients undergoing this procedure are at increased risk of developing nutritional deficiencies by limiting the intake and absorption of many nutrients. Objective: To assess the impact of vitamin D deficiency and calcium in bone in patients after gastric bypass in Roux-en-Y, pointing directly at the type of administration, doses and effects after surgery...
2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/27681502/deficiency-of-fat-soluble-vitamins-in-chronic-pancreatitis-a-systematic-review-and-meta-analysis
#20
Emma Martínez-Moneo, Serena Stigliano, Aleksandra Hedström, Aleksandra Kaczka, Marko Malvik, Alexander Waldthaler, Patrick Maisonneuve, Peter Simon, Gabriele Capurso
BACKGROUND AND AIMS: Chronic pancreatitis (CP) patients are at risk for fat-soluble vitamins (A, D, E, K) deficiency, but available studies are small and heterogeneous. We conducted a systematic review and meta-analysis to determine the prevalence of fat-soluble vitamins deficiency in CP patients. METHODS: Medline was searched up to January 2016 for case series and case-control studies reporting prevalence of fat-soluble vitamin deficiency in CP patients. The prevalent deficiency rate was pooled for included studies, and deficiency rate between CP and controls, with relative odds ratio (OR) and 95% confidence interval (CI) calculated for case-control studies...
September 20, 2016: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
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