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https://www.readbyqxmd.com/read/27913001/cancer-related-fatigue-persistent-pervasive-and-problematic
#1
REVIEW
Lynn H Gerber
Cancer-related fatigue (CRF) is commonly reported by patients with cancer before, during, and after treatment. It is a persistent sense of tiredness that interferes with function, is distressing, and requires monitoring and, possibly, treatment. Fatigue assessment requires objective measures and self-reports, such as Functional Assessment of Cancer Therapy-Fatigue. Significant contributors to CRF include anemia, pain, insomnia, depressive symptoms, and elevated BMI. Elevated inflammatory cytokines, diabetes mellitus, cortisol, and cellular dysregulation have been associated with CRF...
February 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/27912995/rehabilitation-strategies-and-outcomes-of-the-sarcoma-patient
#2
REVIEW
Sean Robinson Smith
Sarcomas are a relatively rare cancer that, depending on the location, can cause significant neuromusculoskeletal dysfunction and require rehabilitation interventions to reduce pain, restore function, and improve quality of life. This review focuses on sarcoma subtypes that frequently cause these complications: bony and soft tissue sarcomas leading to limb salvage or amputation, desmoid tumors, and malignant peripheral nerve sheath tumors. Rehabilitation approaches and outcomes are discussed, as well as considerations for childhood sarcoma survivors transitioning to adulthood...
February 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/27912994/deconstructing-postmastectomy-syndrome-implications-for-physiatric-management
#3
REVIEW
Eric Wisotzky, Nicole Hanrahan, Thomas P Lione, Susan Maltser
Postmastectomy pain syndrome is a common sequela of breast cancer treatment that can lead to impairments and limited participation in work, recreational, and family roles. Pain can originate from multiple anatomic sites. A detailed evaluation to determine the specific cause or causes of pain will help guide the clinician to successfully manage this pain syndrome. There are many available treatments, but more evidence is needed for the efficacy of rehabilitation, pharmacologic, and nonpharmacologic therapy. There is evidence for some effective treatments to prevent this syndrome, but, here also, more research is needed...
February 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/27912953/evaluating-the-effect-of-matricaria-recutita-and-mentha-piperita-herbal-mouthwash-on-management-of-oral-mucositis-in-patients-undergoing-hematopoietic-stem-cell-transplantation-a-randomized-double-blind-placebo-controlled-clinical-trial
#4
Maria Tavakoli Ardakani, Sara Ghassemi, Mahshid Mehdizadeh, Faraz Mojab, Jamshid Salamzadeh, Samaneh Ghassemi, Abbas Hajifathali
OBJECTIVES: To investigate the effects of Matricaria recutita and Mentha piperita on oral mucositis (OM) in patients undergoing hematopoietic stem cell transplantation (HSCT). DESIGN: Randomized double blind placebo controlled clinical trial. SETTING: Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, and Bone Marrow Transplantation Center at Taleghani Teaching Hospital, Tehran, Iran. PARTICIPANTS: Sixty patients undergoing HSCT were randomly assigned to two groups: placebo (n=33), and herbal mouthwash group (n=27)...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27910200/percutaneous-sacroplasty-for-painful-bone-metastases-a-case-report
#5
Jaclyn Yoong, Ronil Vikesh Chandra, Leeroy William, Michael Franco, Tony Goldschlager, Fiona Runacres, Peter Poon
The occurrence of bone metastases is common in patients with advanced cancer. Metastatic bone disease occurs across a range of tumor types, with prostate and breast cancers having the highest incidence. Bone metastases, and associated skeletal-related events, are the most common cause of cancer-related pain. This article is protected by copyright. All rights reserved.
December 2, 2016: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/27908678/avoidance-of-late-rectal-toxicity-after-high-dose-rate-brachytherapy-boost-treatment-for-prostate-cancer
#6
Borut Kragelj, Jernej Zlatic, Lijana Zaletel-Kragelj
PURPOSE: To elucidate potential risk factors important for the appearance of late rectal toxicity (LRT) after high-dose-rate boost treatment (HDRBT) of prostate cancer and to validate the predictive value of the minimal dose to the most exposed 2 cc of rectum received with HDRBT (D2ccrect). METHODS AND MATERIALS: The study of LRT, defined as relative deterioration of defecation problems (RDDP) (stool frequency, pain, rectal bleeding, fecal urgency, and incontinence) during follow-up period, was carried out on 88 patients, consecutively treated from October 2006 through April 2011 with HDRBT of 3 × 6-7 Gy to 50-50...
November 28, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27907881/effect-of-toad-skin-extracts-on-the-pain-behavior-of-cancer-model-mice-and-its-peripheral-mechanism-of-action
#7
Tao Chen, Shen-Jun Yuan, Xue-Qin Yu, Liang-Bo Jiao, Wei Hu, Wang-Long Chen, Bo Xie
The changes in thermal and mechanical hyperalgesia in paw cancer pain model mice and the action mechanism of toad skin extracts (TSE) was investigated. Eighty female mice were subcutaneously injected with saline or inoculated with H22 hepatoma cells in the right hind paw and administration with saline, vehicle, morphine and TSE. The pain behavior was recorded before treatment and at 0.5, 1.0, 1.5, 3 and 6h after initial administration, and thereafter on the 2nd, 4th, 6th, and 8th day after administration. On the last day, samples were collected after the euthanasia for the detection of β-END, CRF, IL-1β, POMC, μ-OR, CD3+, CD8+ and CD4+ in sera and the tumor tissues...
November 28, 2016: International Immunopharmacology
https://www.readbyqxmd.com/read/27907013/development-and-implementation-of-the-ebola-traveler-monitoring-program-and-clinical-outcomes-of-monitored-travelers-during-october-may-2015-minnesota
#8
Aaron DeVries, Pamela Talley, Kristin Sweet, Susan Kline, Patricia Stinchfield, Pritish Tosh, Richard Danila
BACKGROUND: In October 2014, the United States began actively monitoring all persons who had traveled from Guinea, Liberia, and Sierra Leone in the previous 21 days. State public health departments were responsible for monitoring all travelers; Minnesota has the largest Liberian population in the United States. The MDH Ebola Clinical Team (ECT) was established to assess travelers with symptoms of concern for Ebola virus disease (EVD), coordinate access to healthcare at appropriate facilities including Ebola Assessment and Treatment Units (EATU), and provide guidance to clinicians...
2016: PloS One
https://www.readbyqxmd.com/read/27906105/pancreatic-metastases-from-ocular-malignant-melanoma-the-use-of-endoscopic-ultrasound-guided-fine-needle-aspiration-to-establish-a-definitive-cytologic-diagnosis-a-case-report
#9
Diogo Turiani Hourneaux De Moura, Danielle Azevedo Chacon, Ryan Tanigawa, Martin Coronel, Spencer Cheng, Éverson L A Artifon, José Jukemura, Eduardo Guimarães Hourneaux De Moura
BACKGROUND: When encountering solid pancreatic lesions, nonpancreatic primary metastases are rare and differentiating a metastasis from a primary neoplastic lesion is challenging. The clinical presentation and radiologic features can be similar and the possibility of a pancreatic metastasis should be considered when the patient refers to a history of a different primary cancer. Endoscopic ultrasound offers a key anatomical advantage in accessing the pancreas and endoscopic ultrasound-guided fine-needle aspiration has become the gold standard method for diagnosing pancreatic lesions...
December 1, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27906086/massive-adrenal-vein-aneurysm-mimicking-an-adrenal-tumor-in-a-patient-with-hemophilia-a-a-case-report-and-review-of-the-literature
#10
Richard Sleightholm, Steven Wahlmeier, Jeffrey S Carson, Andjela Drincic, Audrey Lazenby, Jason M Foster
BACKGROUND: Visceral venous aneurysms are exceedingly rare, and until now, there have been no reports of this phenomenon in the adrenal vasculature. This report details the first adrenal venous aneurysm reported in the literature. The aneurysm presented as an 18-cm mass that was initially suspected to be a hematoma or tumor on the basis of the complex medical history of the patient, which included hemophilia A and testicular cancer. After surgical excision, pathologic examination confirmed this mass to be a 15...
December 1, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27905367/-celiac-trunk-resection-in-patients-with-pancreatic-cancer-and-severe-pain-syndrome
#11
Yu I Patyutko, M G Abgaryan, N E Kudashkin, A G Kotel'nikov
AIM: To show the advisability, satisfactory tolerance and good analgesic effect of surgery for pancreatic ductal carcinoma with celiac trunk invasion. MATERIAL AND METHODS: Distal subtotal pancreatectomy with resection of celiac trunk and common hepatic artery was made in 21 patients. RESULTS: Early postoperative complications after distal subtotal pancreatectomy with celiac trunk resection occurred in 10 (47.6%) patients. There was no postoperative mortality...
2016: Khirurgiia
https://www.readbyqxmd.com/read/27904860/interventional-therapy-for-pancreatic-cancer
#12
REVIEW
Jianwei Zhu, Zhendong Jin
BACKGROUND: Palliative therapy and primarily chemoradiotherapy are the mainstream treatments in patients with locally advanced or metastatic pancreatic cancer (PC). Conventional endoscopy and endoscopic ultrasound (EUS)-guided interventional therapy has emerged as an important procedure for PC management. In this review, the progress in conventional endoscopy and EUS for PC management is discussed. SUMMARY: For local palliative therapy against PC, EUS-guided fine needle injection (FNI) could deliver different kinds of agents, such as radioactive seeds and fiducials...
October 2016: Gastrointestinal Tumors
https://www.readbyqxmd.com/read/27904731/clinical-usefulness-of-long-term-application-of-fentanyl-matrix-in-chronic-non-cancer-pain-improvement-of-pain-and-physical-and-emotional-functions
#13
Jaewon Lee, Joon Shik Yoon, Jae Hyup Lee, So-Hak Chung, Kyu-Yeol Lee, Young Yul Kim, Jong Moon Kim, Min Ho Kong, Ung Gu Kang, Ye-Soo Park
BACKGROUND: Opioids are recently recommended for those who do not gain adequate pain relief from the use of acetaminophen or nonsteroidal anti-inflammatory drugs. Medical opioids are administered in various routes, and transdermal opioid products that can make up for the weaknesses of the oral or intravenous products have been developed. This study is to evaluate the clinical usefulness of fentanyl matrix in terms of the long-term improvement in pain and physical and mental functions...
December 2016: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/27903435/lack-of-effect-of-selected-sunscreens-applied-on-ex-vivo-human-skin-for-5-methyl-aminolevulinic-acid-penetration-and-protoporphyrin-ix-photoactivation
#14
Hanan Osman-Ponchet, Karine Sevin, Alexandre Gaborit, Magali Kouidhi, Johanna Hanaizi, Pierre Comby, Bernard Ruty, Guy Bouvier
BACKGROUND: Photodynamic therapy (PDT) is a successful treatment for non-melanoma skin cancers. Methyl-aminolevulinate (MAL) is metabolized to protoporphyrin IX (PpIX) which accumulates in the skin lesion and which generates a painful photochemical toxic reaction upon red light exposure. PDT using daylight (DL) exposure is now used to reduce pain and subjects are advised to protect the areas with sunscreen. This work investigated the effect of sunscreen on MAL penetration and PpIX photoactivation in ex vivo human skin...
November 26, 2016: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/27902621/total-laparoscopic-right-hemicolectomy-with-3-step-stapled-intracorporeal-isoperistaltic-ileocolic-anastomosis-for-colon-cancer-an-evaluation-of-short-term-outcomes
#15
Tu Jian-Cheng, Wang Shu-Sheng, Zhang Bo, Fang Jian, Zhou Liang
Laparoscopic right hemicolectomy with extracorporeal anastomosis is a widely used procedure; several authors have published their approach to intracorporeal anastomosis. In this paper, we present an approach developed by us and compare short-term outcomes with those of extracorporeal anastomosis in colon cancer patients.Retrospective review of colon cancer patients treated with laparoscopic right hemicolectomy either with intracorporeal anastomosis (TLG group) or extracorporeal anastomosis (LG group) at the Zhangjiagang Hospital Affiliated to Soochow University between January 2011 and October 2015...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27901478/efficacy-and-safety-of-angiogenesis-inhibitors-in-small-cell-lung-cancer
#16
Heng Lin, Lina Li, Shuimei Luo, Sijing Zhou, Ruifen Shen, Haitao Yang, Huijuan Chen, Xianhe Xie
OBJECTIVE: The purpose of this study was to investigate the efficacy and safety of angiogenesis inhibitors for small-cell lung cancer (SCLC). METHODS: Totally, 16 controlled trials (1898 cases) involving angiogenesis inhibitors plus chemotherapy (ACT group) versus chemotherapy alone group (CT group) were identified from PubMed, EMBASE, Cochrane Library and Wanfang Data before March 2016. RESULTS: Compared with CT group, ACT group obtained a significant benefit on objective response rate (ORR) (RR = 1...
November 25, 2016: Oncotarget
https://www.readbyqxmd.com/read/27900729/radical-resection-of-t1-pancreatic-adenocarcinoma-with-a-pseudocyst-of-the-tail-due-to-acute-obstructive-pancreatitis-report-of-a-case
#17
Yuki Fujiwara, Fumitake Suzuki, Masaru Kanehira, Yasuro Futagawa, Tomoyoshi Okamoto, Katsuhiko Yanaga
A 53-year-old male visited his primary physician for epigastric and back pain. Abdominal-enhanced computed tomography (CT) revealed a simple cyst of the pancreatic tail attached to the stomach. A distal main pancreatic duct (MPD) was clearly dilated, but no pancreatic tumor was identified around the stenosis of MPD by CT scan and magnetic resonance cholangiopancreatography (MRCP). Endoscopic retrograde pancreatography (ERP) revealed stenosis and distal dilation of the MPD located between the body and tail of the pancreas...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27900088/favorable-control-of-advanced-colon-adenocarcinoma-with-severe-bone-marrow-metastasis-a-case-report
#18
Fumiyasu Hanamura, Yoshihiro Shibata, Tsuyoshi Shirakawa, Miyuki Kuwayama, Hisanobu Oda, Hiroshi Ariyama, Kenichi Taguchi, Taito Esaki, Eishi Baba
Colorectal cancer (CRC) has a propensity to metastasize to the liver, lungs and regional abdominal lymph nodes, but rarely to the bone marrow. A 60-year-old man presented to the National Hospital Organization Kyushu Cancer Center with a 4-week history of persistent lower back pain, anorexia and difficulty defecating. Complete blood count revealed severe thrombocytopenia and erythroblastosis, suggesting a hematological malignancy. However, the bone marrow examination demonstrated involvement by a moderately to poorly differentiated adenocarcinoma, but no hematopoietic abnormalities...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27899777/-physical-activity-in-patients-with-gastrointestinal-cancer-undergoing-outpatient-chemotherapy
#19
Megumi Iwakoshi, Tetsuya Tsuji, Hiromasa Takaishi, Yasuo Hamamoto, Tsunehiro Takahashi, Takashi Endo, Yuko Kitagawa, Meigen Liu
PURPOSE: To determine factors affecting physical activity in outpatients with gastrointestinal cancer. METHODS: This observational study applied the International Physical Activity Questionnaire(IPAQ)to identify factors affecting physical activity in outpatients(male, n=51; female, n=24; mean age, 64.2±10.2 years)with gastrointestinal cancer undergoing chemotherapy. Relationships between the main outcome measures, total weekly physical activity score(TPA)and total weekly energy expenditure(TEE), and patient background factors were analyzed...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/27899312/exploratory-factor-analysis-of-nrg-oncology-s-university-of-washington-quality-of-life-questionnaire-rtog-modification
#20
Stephanie L Pugh, Gwen Wyatt, Raimond K W Wong, Stephen M Sagar, Bevan Yueh, Anurag K Singh, Min Yao, Phuc Felix Nguyen-Tan, Sue S Yom, Francis S Cardinale, Khalil Sultanem, D Ian Hodson, Greg A Krempl, Ariel Chavez, Alexander M Yeh, Deborah W Bruner
CONTEXT: The 15-item University of Washington Quality of Life questionnaire - Radiation Therapy Oncology Group (RTOG) modification (UW-QOL-RTOG modification) has been used in several trials of head and neck cancer conducted by NRG Oncology such as RTOG 9709, RTOG 9901, RTOG 0244, and RTOG 0537. OBJECTIVES: This study is an exploratory factor analysis (EFA) to establish validity and reliability of the instrument subscales. METHODS: EFA on the UW-QOL - RTOG modification was conducted using baseline data from NRG Oncology's RTOG 0537, a trial of acupuncture-like transcutaneous electrical nerve stimulation in treating radiation-induced xerostomia...
November 26, 2016: Journal of Pain and Symptom Management
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