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https://www.readbyqxmd.com/read/29352452/the-determinants-of-reduced-dietary-intake-in-hospitalised-colorectal-cancer-patients
#1
Anne van der Werf, Katherine Arthey, Michael Hiesmayr, Isabella Sulz, Karin Schindler, Alessandro Laviano, Jacqueline Langius, Marian de van der Schueren
PURPOSE: Patients with colorectal cancer (CRC) often experience malnutrition and weight loss, largely resulting from reduced dietary intake. The aim of this study was to identify determinants of reduced dietary intake in order to facilitate early recognition of malnutrition and optimise nutritional treatment. METHODS: Data from nutritionDay, an international 1-day survey investigating patient, disease and food profiles, were used. To identify determinants of dietary intake, defined as normal vs...
January 19, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29351803/psychometric-properties-and-measurement-equivalence-of-the-multidimensional-fatigue-syndrome-inventory-short-form-mfsi-sf-amongst-breast-cancer-and-lymphoma-patients-in-singapore
#2
Alexandre Chan, Claire Lew, Xiao Jun Wang, Terence Ng, Jung-Woo Chae, Hui Ling Yeo, Maung Shwe, Yan Xiang Gan
BACKGROUND: Currently, several fatigue measurement instruments are available to evaluate and measure cancer-related fatigue. Amongst them, Multidimensional Fatigue Syndrome Inventory-Short Form (MFSI-SF) is a self-reported instrument and a multidimensional scale that aims to capture the global, somatic, affective, cognitive and behavioural symptoms of fatigue. This study examines the psychometric properties and measurement equivalence of the English and Chinese versions of MFSI-SF in breast cancer and lymphoma patients in Singapore...
January 19, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29351123/accuracy-of-18f-naf-pet-ct-in-bone-metastasis-detection-and-its-effect-on-patient-management-in-patients-with-breast-carcinoma
#3
Wouter A M Broos, Friso M van der Zant, Maurits Wondergem, Remco J J Knol
OBJECTIVE: Determination of the accuracy of sodium fluorine-18-fluoride (F-NaF) PET/computed tomography (CT) for the evaluation of bone metastases, and the impact on patient management in breast cancer patients. PATIENTS AND METHODS: Patients with breast cancer, referred for F-NaF PET/CT between February 2014 and June 2016, were included in a database. Baseline characteristics, clinical indication, definitive diagnosis according to follow-up data, as well as changes in patient management were recorded...
January 18, 2018: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29350481/emotion-regulation-and-positive-affect-in-the-context-of-salivary-alpha-amylase-response-to-pain-in-children-with-cancer
#4
Brooke N Jenkins, Douglas A Granger, Ryan J Roemer, Ariana Martinez, Tara K Torres, Michelle A Fortier
BACKGROUND: Children with cancer routinely undergo painful medical procedures invoking strong physiological stress responses. Resilience to this pain may be conferred through resources such as emotion regulation strategies and positive affect. PROCEDURE: This study measured dispositional positive affect in children with cancer (N = 73) and randomly assigned participants to one of three emotion regulation strategy conditions (distraction, reappraisal, or reassurance)...
January 19, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29350307/living-with-chronic-pain-perceptions-of-breast-cancer-survivors
#5
Ting Bao, Andrew Seidman, Qing Li, Christina Seluzicki, Victoria Blinder, Salimah H Meghani, John T Farrar, Jun J Mao
PURPOSE: Breast cancer treatments may lead to chronic pain. For some breast cancer survivors (BCS), this experience can develop into the perception of living with chronic pain. The majority of BCS are postmenopausal and have hormone receptor-positive (HR+) breast cancer requiring aromatase inhibitors (AIs). Neither the prevalence nor risk factors associated with the perception of living with chronic pain among this population are well defined. METHODS: We conducted a cross-sectional survey among postmenopausal, HR+ BCS who previously took or were currently taking AIs...
January 19, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29349713/patient-reported-outcomes-of-catheter-based-accelerated-partial-breast-brachytherapy-and-whole-breast-irradiation-a-single-institution-experience
#6
Krishan R Jethwa, Mohamed M Kahila, Kristin C Mara, William S Harmsen, David M Routman, Geralyn M Pumper, Kimberly S Corbin, Jeff A Sloan, Kathryn J Ruddy, Tina J Hieken, Sean S Park, Robert W Mutter
PURPOSE: Accelerated partial breast irradiation (APBI) and whole breast irradiation (WBI) are treatment options for early-stage breast cancer. The purpose of this study was to compare patient-reported-outcomes (PRO) between patients receiving multi-channel intra-cavitary brachytherapy APBI or WBI. METHODS: Between 2012 and 2015, 131 patients with ductal carcinoma in situ (DCIS) or early stage invasive breast cancer were treated with adjuvant APBI (64) or WBI (67) and participated in a PRO questionnaire...
January 18, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29349712/highly-favorable-physiological-responses-to-concurrent-resistance-and-high-intensity-interval-training-during-chemotherapy-the-optitrain-breast-cancer-trial
#7
Sara Mijwel, Malin Backman, Kate A Bolam, Emil Olofsson, Jessica Norrbom, Jonas Bergh, Carl Johan Sundberg, Yvonne Wengström, Helene Rundqvist
BACKGROUND: Advanced therapeutic strategies are often accompanied by significant adverse effects, which warrant equally progressive countermeasures. Physical exercise has proven an effective intervention to improve physical function and reduce fatigue in patients undergoing chemotherapy. Effects of high-intensity interval training (HIIT) in this population are not well established although HIIT has proven effective in other clinical populations. The aim of the OptiTrain trial was to examine the effects of concurrent resistance and high-intensity interval training (RT-HIIT) or concurrent moderate-intensity aerobic and high-intensity interval training (AT-HIIT), to usual care (UC) on pain sensitivity and physiological outcomes in patients with breast cancer during chemotherapy...
January 18, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29346613/review-of-chronic-non-cancer-pain-research-among-aboriginal-people-in-canada
#8
Nancy Julien, Anaïs Lacasse, Oscar Labra, Hugo Asselin
Purpose: Aboriginal people in Canada are disproportionately affected by chronic illnesses, compared to non-Aboriginal Canadians. The purpose of this review was to determine whether differences exist between the two groups with respect to chronic non-cancer pain (CNCP) in order to better inform clinical practice and to identify research gaps. Data sources: Four electronic databases were searched for the period of 1990-2015. Study selection: Only English and French language original studies that examined CNCP prevalence, assessment tools and beliefs among Aboriginal people in Canada were considered...
January 16, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29344788/intracorporeal-versus-extracorporeal-anastomosis-after-laparoscopic-left-colectomy-for-splenic-flexure-cancer-results-from-a-multi-institutional-audit-on-181-consecutive-patients
#9
Marco Milone, Pierluigi Angelini, Giovanna Berardi, Morena Burati, Francesco Corcione, Paolo Delrio, Ugo Elmore, Maria Lemma, Michele Manigrasso, Alfredo Mellano, Andrea Muratore, Ugo Pace, Daniela Rega, Riccardo Rosati, Ernesto Tartaglia, Giovanni Domenico De Palma
Although intracorporeal anastomosis has been demonstrated to be safe and effective after right colectomy, limited data are available about its efficacy after left colectomy for colon cancer located in splenic flexure. A multi-institutional audit was designed, including 92 patients who underwent laparoscopic left colectomy with intracorporeal anastomosis (IA) compared with 89 matched patients who underwent a laparoscopic left colectomy with extracorporeal anastomosis (EA). There was no significant difference in terms of age, sex, BMI, and ASA score between the two groups...
January 17, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29344766/patient-reported-symptoms-before-palliative-radiotherapy-predict-survival-differences
#10
Carsten Nieder, Thomas A Kämpe, Adam Pawinski, Astrid Dalhaug
BACKGROUND: Widely used prognostic scores, e. g., for brain or bone metastases, are based on disease- and patient-related factors such as extent of metastases, age and performance status, which were available in the databases used to develop the scores. Few groups were able to include patient-reported symptoms. In our department, all patients were assessed with the Edmonton Symptom Assessment System (ESAS, a one-sheet questionnaire addressing 11 major symptoms and wellbeing on a numeric scale of 0-10) at the time of treatment planning since 2012...
January 17, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29344736/predictors-of-analgesic-efficacy-of-neurolytic-celiac-plexus-block-in-patients-with-unresectable-pancreatic-cancer-the-importance-of-timing
#11
Duck Mi Yoon, Kyung Bong Yoon, In Chan Baek, Seo Hee Ko, Shin Hyung Kim
BACKGROUND: Neurolytic celiac plexus block (NCPB) is a safe and effective method for reducing abdominal cancer pain. However, the analgesic efficacy of NCPB is not always guaranteed. The aim of this retrospective study was to identify predictors for the analgesic efficacy of NCPB in patients with unresectable pancreatic cancer. METHODS: Patients with unresectable pancreatic cancer who underwent NCPB from 2006 to 2015 were enrolled. Good analgesia after NCPB was defined as ≥ 50% reduction in pain score at day 30...
January 17, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29344183/a-patient-with-chronic-myeloid-leukemia-and-situs-inversus-totalis-a-case-report
#12
Yunxia Sun, Xiaoli Li, Lijun Li, Huan Liu, Qian Xu, Bei Liu
In the present study, a case of chronic myeloid leukemia (CML) with complete situs inversus in a 68-year-old female patient was reported. The patient presented with general weakness, abdominal distension and tenderness in the right hypochondrium. A chest X-ray revealed a right-sided heart. Ultrasonography revealed situs inversus totalis. A bone marrow smear demonstrated CML in the accelerated phase. Imatinib mesylate was subsequently administered; the patient stopped taking imatinib mesylate following discharge from the hospital...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29343971/assessment-of-the-cardiac-safety-between-cetuximab-and-panitumumab-as-single-therapy-in-chinese-chemotherapy-refractory-mcrc
#13
Xue-Miao Tang, Hao Chen, Qing Li, Yiling Song, Shuping Zhang, Xiao-Shuan Xu, Yiwei Xu, Shulin Chen
Objective: The cardiac safety of cetuximab and panitumumab, particularly as single agents, has not been investigated extensively. This trial was designed to specifically evaluate the cardiac safety of cetuximab and panitumumab as single therapy in Chinese chemotherapy-refractory metastatic colorectal cancer (mCRC) patients. Patients and methods: Sixty-one patients received cetuximab at an initial dose of 400 mg/m2 intravenously over 120 minutes on day 1 (week 1), followed by a maintenance dose of 250 mg/m2 intravenously over 60 minutes on day 1 of each 7-day cycle...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29343246/influence-of-preoperative-life-satisfaction-on-recovery-and-outcomes-after-colorectal-cancer-surgery-a-prospective-pilot-study
#14
B Romain, O Rohmer, S Schimchowitsch, M Hübner, J B Delhorme, C Brigand, S Rohr, D Guenot
BACKGROUND: Colorectal surgery has an important impact on a patient's quality of life, and postoperative rehabilitation shows large variations. To enhance the understanding of recovery after colorectal cancer, health-related quality of life has become a standard outcome measurement for clinical care and research. Therefore, we aimed to correlate the influence of preoperative global life satisfaction on subjective feelings of well-being with clinical outcomes after colorectal surgery. METHODS: In this pilot study of consecutive colorectal surgery patients, various dimensions of feelings of preoperative life satisfaction were assessed using a self-rated scale, which was validated in French...
January 17, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29341428/epigenetic-silencing-of-tap1-in-aldefluor-breast-cancer-stem-cells-contributes-to-their-enhanced-immune-evasion
#15
Mohammad Sultan, Dejan Vidovic, Arianne S Paine, Thomas T Huynh, Krysta M Coyle, Margaret L Thomas, Brianne M Cruickshank, Cheryl A Dean, Derek R Clements, Youra Kim, Kristin Lee, Shashi A Gujar, Ian C Weaver, Paola Marcato
Avoiding detection and destruction by immune cells is key for tumor initiation and progression. The important role of cancer stem cells (CSC) in tumor initiation has been well established, yet their ability to evade immune detection and targeting is only partly understood. To investigate the ability of breast CSCs to evade immune detection we identified a highly tumorigenic population in a spontaneous murine mammary tumor based on increased aldehyde dehydrogenase (ALDH) activity. We performed tumor growth studies in immunocompetent and immunocompromised mice...
January 17, 2018: Stem Cells
https://www.readbyqxmd.com/read/29340015/apatinib-alone-or-combined-with-radiotherapy-in-metastatic-prostate-cancer-results-from-a-pilot-multicenter-study
#16
Feng Zhao, Wei Tian, Ming Zeng, Jianling Xia, Honglin Hu, Xinbao Hao, Liangfu Han, Hao Liu, Yangke He, Xueqiang Zhu, Liang Liang, Rui Ao, Min Wei, Lili Deng, Yuquan Wei
Background: To study safety and efficacy of apatinib in combination of radiotherapy in patients with symptomatic bony disease prostate cancer(SBPC), based on the potential synergistic antitumor activity between apatinib and Radiation Therapy (RT). Patients and methods: In phase I dose escalation part, 18 patients received apatinib dose at 250 mg every other day, 250 mg daily and 500 mg daily. In phase II part, the 250 mg daily cohorts were expanded to 20 patients in combination of RT (6 Gy/fraction, 5 fraction in total), one patient lost followed up and excluded the study, comparing with RT alone cohort with 10 patients, ratio of RT to RT + apatinib was 1 to 2...
December 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29339302/bilateral-ureteral-stent-remove-after-15-years-a-case-report
#17
Stefano Restaino, Francesco Fanfani, Matteo Vittori, Alessandro D'Addessi, Giovanni Scambia, Barbara Costantini
We present the first case of patients with more than 15 years forgotten ureteral stents. A 68-year-old woman affected by cervical cancer, who underwent a radical hysterectomy in 1997 and reported a placement of bilateral ureteral stents. She was admitted in our Hospital for stranguria, dysuria, and lower back pain for 10 days. Preoperative radiological evaluation showed the persistence of ureteral stents. She never removed the stent which had been positioned for a long period of time(since 1997). We proceed to remove in general anaesthesia bilateral stents by urethral cystoscopic...
January 12, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29339292/selective-hcn1-block-as-a-strategy-to-control-oxaliplatin-induced-neuropathy
#18
F Resta, L Micheli, A Laurino, V Spinelli, T Mello, L Sartiani, L Di Cesare Mannelli, E Cerbai, C Ghelardini, M N Romanelli, G Mannaioni, A Masi
Chemotherapy-Induced Peripheral Neuropathy (CIPN) is the most frequent adverse effect of pharmacological cancer treatments. The occurrence of neuropathy prevents the administration of fully-effective drug regimen, affects negatively the quality of life of patients, and may lead to therapy discontinuation. CIPN is currently treated with anticonvulsants, antidepressants, opioids and non-opioid analgesics, all of which are flawed by insufficient anti-hyperalgesic efficacy or addictive potential. Understandably, developing new drugs targeting CIPN-specific pathogenic mechanisms would dramatically improve efficacy and tolerability of anti-neuropathic therapies...
January 12, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/29338904/pain-and-its-impact-on-the-functional-ability-in-children-treated-at-the-children-s-cancer-center-of-lebanon
#19
Dina Madi, Michael Clinton
PURPOSE: The purpose of this study was to describe the characteristics of pain in children under treatment at the Children Cancer Centre of Lebanon at the American University of Beirut Medical Centre. Design and Methods A cross-sectional correlational survey was used. The Adolescent Pediatric Pain Tool and the Functional Disability Inventory were used to examine the characteristics of pain experienced in a consecutive sample of children treated at the CCCL and its impact on their functional abilities...
January 12, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29338806/cancer-pain-management-needs-and-perspectives-of-patients-from-chinese-backgrounds-a-systematic-review-of-the-chinese-and-english-literature
#20
Xiangfeng Xu, Tim Luckett, Alex Yueping Wang, Melanie Lovell, Jane L Phillips
OBJECTIVE: More than half of all cancer patients experience unrelieved pain. Culture can significantly affect patients' cancer pain-related beliefs and behaviors. Little is known about cultural impact on Chinese cancer patients' pain management. The objective of this review was to describe pain management experiences of cancer patients from Chinese backgrounds and to identify barriers affecting their pain management. METHOD: A systematic review was conducted adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
January 17, 2018: Palliative & Supportive Care
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