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https://www.readbyqxmd.com/read/26869838/affective-preclinical-modeling-of-psychiatric-disorders-taking-imbalanced-primal-emotional-feelings-of-animals-seriously-in-our-search-for-novel-antidepressants
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Jaak Panksepp
Preclinical animal models of psychiatric disorders are of critical importance for advances in development of new psychiatric medicine. Regrettably, behavior-only models have yielded no novel targeted treatments during the past half-century of vigorous deployment. This may reflect the general neglect of experiential aspects of animal emotions, since affective mental states of animals supposedly cannot be empirically monitored. This supposition is wrong-to the extent that the rewarding and punishing aspects of emotion circuit arousals reflect positive and negative affective states...
December 2015: Dialogues in Clinical Neuroscience
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