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https://www.readbyqxmd.com/read/28454390/expression-of-novel-cancer-testis-antigen-tmem31-increases-during-metastatic-melanoma-progression
#1
Jiaqiang Li, Xiaowen Zou, Cailing Li, Jianhua Zhong, Yan Chen, Xiaoyue Zhang, Fuming Qi, Mengshuo Li, Zhiming Cai, Aifa Tang
Cancer/testis (CT) antigens are promising targets for immunotherapy due to their restricted expression in the germ cells of the testis in healthy tissue and high immunogenicity. The aim of the present study was to determine whether transmembrane protein 31 (TMEM31) is a CT antigen and to investigate the pattern of TMEM31 expression during the progression of melanoma. The pattern of expression of human TMEM31 mRNA in multiple human tissues was determined through reverse transcription-polymerase chain reaction analysis...
April 2017: Oncology Letters
https://www.readbyqxmd.com/read/28446021/evaporation-of-drops-containing-silica-nanoparticles-of-varying-hydrophobicity-exploiting-particle-particle-interactions-for-additive-free-tunable-deposit-morphology
#2
Manos Anyfantakis, Damien Baigl, Bernard P Binks
We describe the systematic and quantitative investigation of a large number of patterns that emerge after the evaporation of aqueous drops containing fumed silica nanoparticles of varying wettability, for an extended particle concentration range. We show that for a chosen system, the dry pattern morphology is mainly determined by particle-particle interactions (Coulomb repulsion and hydrophobic attraction) in the bulk. These depend on both particle hydrophobicity as well as particle concentration within the drop...
April 27, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28445998/infrared-raman-and-magnetic-resonance-spectroscopic-study-of-sio2-c-nanopowders
#3
Dariya Savchenko, Vladimir Vorliček, Ekaterina Kalabukhova, Aleksandr Sitnikov, Andrii Vasin, Dmytro Kysil, Stanislav Sevostianov, Valentyn Tertykh, Alexei Nazarov
Optical and magnetic properties of SiO2:C nanopowders obtained by chemical and thermal modification of fumed silica were studied by Fourier transform infrared spectroscopy, Raman, continuous wave (CW) electron paramagnetic resonance (EPR), echo-detected EPR and pulsed electron nuclear double resonance (ENDOR) spectroscopy. Two overlapping signals of Lorentzian lineshape were detected in CW EPR spectra of the initial SiO2:C. The EPR signal at g = 2.0055(3) is due to the silicon dangling bonds, which vanishes after thermal annealing, and the second EPR signal at g = 2...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28433174/corrigendum-to-production-of-a-low-molecular-weight-heparin-production-using-recombinant-glycuronidas-carbohydr-polym-134-2015-151-157
#4
Guowei Su, Linhong Li, Haichan Huang, Weihong Zhong, Ping Yu, Fuming Zhang, Robert J Linhardt
No abstract text is available yet for this article.
July 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28426386/new-zealanders-working-non-standard-hours-also-have-greater-exposure-to-other-workplace-hazards
#5
Sarah M Jay, Philippa H Gander, Amanda Eng, Soo Cheng, Jeroen Douwes, Lis Ellison-Loschmann, Dave McLean, Neil Pearce, Andrea 'tMannetje
Exposure to workplace hazards, such as dust, solvents, and fumes, has the potential to adversely affect the health of people. However, the effects of workplace hazards on health may differ when exposure occurs at different times in the circadian cycle, and among people who work longer hours or who do not obtain adequate sleep. The aim of the present study was to document exposures to workplace hazards across a national sample of New Zealanders, comparing people who work a standard 08:00 -17:00 h Monday-to-Friday working week (Std hours) and those who do not (N-Std hours)...
2017: Chronobiology International
https://www.readbyqxmd.com/read/28422595/microleakage-of-sealants-after-phosphoric-acid-er-yag-laser-and-air-abrasion-enamel-conditioning-systematic-review-and-meta-analysis
#6
Ana Caroline Fumes, Daniele Lucca Longo, Andiara De Rossi, Tatiana Kelly da Silva Fidalgo, Francisco Wanderley Garcia de Paula E Silva, Maria Cristina Borsatto, Erika Calvano Küchler
PURPOSE: The aim of this systematic review and meta-analysis is to answer the focused question: Does the application of phosphoric acid, Er:YAG laser and air abrasion enamel conditioning methods previous to the oclusal sealant application in human permanent molars influence the microleakage? STUDY DESIGN: A literature research was carried out in the Pubmed Medline, Web of Science, Scopus and Cochrane databases using with the MeSH terms and keyword search strategy...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28420806/the-association-of-occupational-metals-exposure-and-oxidative-damage-telomere-shortening-in-fitness-equipments-manufacturing-workers
#7
Jiunn-Liang Ko, Yu-Jung Cheng, Guan-Cen Liu, I-Lun Hsin, Hsiu-Ling Chen
The welding is the major working process in fitness equipment manufacturing industry, and International Agency for Research on Cancer has classified welding fumes as possibly carcinogenic to humans (Group 2B). The present study aimed to evaluate associations between the occupational exposure of metals and oxidative damage and telomere length shortening in workers involved in the manufacture of fitness equipment. The blood metal concentrations were monitored and malondialdehyde (MDA), alkaline Comet assay was determined as oxidative damage in 117 workers from two representative fitness equipment manufacturing plants...
April 14, 2017: Industrial Health
https://www.readbyqxmd.com/read/28419893/carbon-monoxide-related-fatalities-a-60-year-single-institution-experience
#8
Martin Janík, Michaela Ublová, Štepánka Kučerová, Petr Hejna
OBJECTIVE: Though carbon monoxide (CO) poisonings account currently for a relatively small percentage of total non-natural deaths in Europe, they represent a serious public health burden and significant component of avoidable mortality in many countries. Our aim was to investigate long-term trends and to determine epidemiologic characteristics of the CO-related deaths in the Czech Republic, recorded at the Department of Forensic Medicine in Hradec Králové. METHODS: This was an autopsy-based single-centre retrospective cohort study of all fatalities caused by CO poisoning over six decades (1947-2006)...
April 13, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28415716/single-nucleotide-polymorphism-rs3124599-in-notch1-is-associated-with-the-risk-of-lung-cancer-in-northeast-chinese-non-smoking-females
#9
Xiaowei Quan, Zhihua Yin, Xue Fang, Baosen Zhou
Lung cancer is one of the most common cancers and the main cause of cancer-related deaths. Notch1 might play a part in tumorigenesis of lung cancer. Here we explored the relationship of three SNPs (rs3124599, rs3124607 and rs3124594) in Notch1 with the risk and the survival of lung cancer in non-smoking females, including 556 cases and 395 controls. Chi-square tests, logistic regression analysis and crossover analysis were conducted to estimate the association between SNPs and the risk of lung cancer and the interaction between SNPs and environmental exposure...
March 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28414461/a-tetraphenylethene-naphthyridine-based-aiegen-tpen-with-dual-mechanochromic-and-chemosensing-properties
#10
Shahida Umar, Ajay Kumar Jha, Deepak Purohit, Atul Goel
Synthesis of new tetraphenylethene (TPE) conjugates via an innocuous route led to the revelation of a unique TPE-based aggregation-induced emissive fluorogen 3 (TPEN), which showed an interesting mechanochromic property when the emission was changed from blue to green upon grinding and green to blue upon fuming. The mechanochromic property of TPEN has been explored to prepare ink-free rewritable paper for security documentation. A detailed photophysical investigation of the TPE-naphthyridine scaffold led to the discovery of its high sensitivity to silver ions (Ag(+)) over other metal ions with a detection limit of 0...
April 21, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28411035/altered-ion-transport-in-normal-human-bronchial-epithelial-cells-following-exposure-to-chemically-distinct-metal-welding-fume-particles
#11
Jeffrey S Fedan, Janet A Thompson, Terence G Meighan, Patti C Zeidler-Erdely, James M Antonini
Welding fume inhalation causes pulmonary toxicity, including susceptibility to infection. We hypothesized that airway epithelial ion transport is a target of fume toxicity, and investigated the effects of fume particulates from manual metal arc-stainless steel (MMA-SS) and gas metal arc-mild steel (GMA-MS) on ion transport in normal human bronchial epithelium (NHBE) cultured in air-interface. MMA-SS particles, more soluble than GMA-MS particles, contain Cr, Ni, Fe and Mn; GMA-MS particles contain Fe and Mn...
April 12, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28409909/macroporous-silica-with-thick-framework-for-steam-stable-and-high-performance-poly-ethyleneimine-silica-co2-adsorbent
#12
Kyungmin Min, Woosung Choi, Minkee Choi
Poly(ethyleneimine) (PEI)/silica has been widely studied as a solid adsorbent for post-combustion CO2 capture. In this work, a highly macroporous silica (MacS) synthesized by secondary sintering of fumed silica is compared with various mesoporous silicas having different pore structures as a support for PEI. Silicas with large pore diameter and volume enabled high CO2 adsorption kinetics and capacity because pore occlusion by the supported PEI was minimized. The steam stability of the silica structures increased with the silica framework thickness owing to suppressed framework ripening...
April 13, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28408655/military-small-arms-fire-in-association-with-acute-decrements-in-lung-function
#13
Anne Katrine Borander, Øyvind Albert Voie, Kjetil Longva, Tor Erik Danielsen, Svein Grahnstedt, Leiv Sandvik, Johny Kongerud, Liv Ingunn Bjoner Sikkeland
OBJECTIVE: After introduction of unleaded ammunition, Norwegian Armed Forces received reports of acute respiratory symptoms in soldiers after exposure to fumes from firing the standard weapon, HK416. The aim of the present study was to examine lung function before and after exposure to fumes from HK416 in a double-blinded standardised study design using three different types of ammunition. METHODS: Fifty-four healthy, non-smoking male volunteers (19-62 years) fired the weapons for 60 min with either leaded, unleaded or 'modified' unleaded ammunition...
April 13, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28406626/excimer-monomer-photoluminescence-mechanochromism-and-vapochromism-of-pentiptycene-containing-cyclometalated-platinum-ii-complexes
#14
Che-Jen Lin, Yi-Hung Liu, Shie-Ming Peng, Teruo Shinmyozu, Jye-Shane Yang
The ability of the bulky H-shaped pentiptycene scaffold in promoting the mechanochromic and vapochromic luminescence properties for organometallic materials has been demonstrated with the N^C^N cyclometalated platinum(II) complexes [X-NCNPtY], where X = Br or Pa, the substituent on the terdentate dipyridylbenzene N^C^N ligand, and Y = Cl or Pa, the ancillary ligand, in which Pa = pentiptycene acetylene. Intermolecular interactions between the planar NCNPt cores are described by π-π and d-π interactions with negligible Pt(II)···Pt(II) bonding, corresponding to ligand-centered excimer rather than metal-metal-to-ligand charge-transfer emission, for these platinum(II) complexes in aggregates and in the solid state...
April 13, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28406364/fume-emissions-from-a-low-cost-3-d-printer-with-various-filaments
#15
Evan L Floyd, Jun Wang, James L Regens
3-D printing is an additive manufacturing process involving the injection of melted thermoplastic polymers, which are then laid down in layers to achieve a pre-designed shape. The heated deposition process raises concerns of potential aerosol and volatile organic compounds (VOC) emission and exposure. The decreasing cost of desktop 3-D printers has made the use of 3-D printers more acceptable in non-industrial workplaces lacking sufficient ventilation. Meanwhile, little is known about the characteristics of 3-D printing fume emission...
April 13, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28395311/exploring-manganese-fractionation-using-a-sequential-extraction-method-to-evaluate-welders-gas-metal-arc-welding-exposures-during-heavy-equipment-manufacturing
#16
Kevin W Hanley, Ronnee Andrews, Steven Bertke, Kevin Ashley
The National Institute for Occupational Safety and Health (NIOSH) has conducted an occupational exposure assessment study of manganese (Mn) in welding fume at three factories where heavy equipment was manufactured. The objective of this study was to evaluate exposures to different Mn fractions using a sequential extraction procedure. One hundred nine worker-days were monitored for either total or respirable Mn during gas metal arc welding. The samples were analyzed using an experimental method to separate different Mn fractions based on selective chemical solubility...
January 1, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/28389379/exposure-to-welding-fumes-activates-dna-damage-response-and-redox-sensitive-transcription-factor-signalling-in-sprague-dawley-rats
#17
Jayaraman Krishnaraj, Jaganathan Kowshik, Robin Sebastian, Sathees C Raghavan, Siddavaram Nagini
BACKGROUND: Occupational exposure to welding fumes containing a complex mixture of genotoxic heavy metals, radiation, gases and nanoparticles poses a serious health hazard to welders. Since their categorization as possible carcinogens, welding fumes have gained increasing attention as high priority agents for risk assessment. OBJECTIVE: The present study was undertaken to investigate the effects of welding fume inhalation on oxidative stress, DNA damage response (DDR), and nuclear factor erythroid 2-related factor-2 (Nrf2) and nuclear factor kappa B (NFκB) signalling in the lung tissues of male Sprague-Dawley rats...
April 5, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28376247/phenothiazinyl-boranes-a-new-class-of-aie-luminogens-with-mega-stokes-shift-mechanochromism-and-mechanoluminescence
#18
C Arivazhagan, Arunava Maity, K Bakthavachalam, Arijit Jana, Aniket Chowdhury, Suraj Kumar Panigrahi, Eringathodi Suresh, Partha Sarathi Mukherjee, Amitava Das, Sundargopal Ghosh
Phenothiazine with dimesityl boron moiety, a new class of aminoboranes with Boron (B)-Nitrogen (N) linkage, has been synthesized. These aminoboranes exhibit interesting photophysical behaviors including aggregation-induced emission (AIE), mechanochromism (MC), mechanoluminescence (ML) and mega Stokes shift (up to 312 nm in hexane). The solid-state emission of the aminoboranes can be switched reversibly by grinding-fuming processes. Furthermore, the phenothiazine derivative with a bromo and an arylborane group at 3 and 7 positions exhibits bright mechanoluminescence...
April 4, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28375782/the-potential-hazardous-effect-of-exposure-to-iron-dust-in-egyptian-smoking-and-non-smoking-welders
#19
Naglaa Abd El Khalik Gobba, Abdel-Maksoud A Hussien, Dalia E El Sharawy, Mohammed Abdalla Hussein
Exposure to iron dust and welding fumes is widespread and may increase the risk of lung inflammation. The aim of this study was to identify associations between exposure to iron/ welding fumes and the levels of inflammatory parameters and allergic mediators among 120 Egyptian males. Forty non-smoking and 40 smoking Egyptian welders as well as 40 healthy volunteers who were never exposed to welding fumes and non-smoking were enrolled in the study. Peak expiratory flow rates (PEFR) that were assessed at the shift of work in the working days revealed an impairment in lung function with the smoking workers showing the worse results, followed by the non-smoking ones as compared to the healthy volunteers...
April 4, 2017: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/28366955/signs-and-symptoms-of-mercury-exposed-gold-miners
#20
Stephan Bose-O'Reilly, Ludovic Bernaudat, Uwe Siebert, Gabriele Roider, Dennis Nowak, Gustav Drasch
OBJECTIVES: Gold miners use mercury to extract gold from ore adding liquid mercury to the milled gold-containing ore. This results in a mercury-gold compound, called amalgam. Miners smelt this amalgam to obtain gold, vaporizing it and finally inhaling the toxic mercury fumes. The objective was to merge and analyze data from different projects, to identify typical signs and symptoms of chronic inorganic mercury exposure. MATERIAL AND METHODS: Miners and community members from various artisanal small-scale gold mining areas had been examined (Philippines, Mongolia, Tanzania, Zimbabwe, Indonesia)...
March 30, 2017: International Journal of Occupational Medicine and Environmental Health
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