keyword
https://read.qxmd.com/read/37006645/thyroid-dysfunction-in-women-of-reproductive-age-laboratory-protocol-for-infertility-evaluation
#1
JOURNAL ARTICLE
A A Akande, I A Isah, I S Aliyu, A G Adesiyun
BACKGROUND: Infertility in developing counties worldwide is associated with many social, financial, and medical challenges. With a prevalence rate of between 10 - 14 % and biochemical etiology of about 80% of the cases among Nigerian women, laboratory diagnosis has gradually assumed an important role in improved diagnosis. OBJECTIVE: The aim was to evaluate the prevalence of thyroid dysfunction in infertility and need to evaluate. METHODS: This was a descriptive cross-sectional case study of one hundred and twenty-five (125) women selected by stratified random sampling method into two groups of primary and secondary infertility...
June 2022: Annals of Ibadan Postgraduate Medicine
https://read.qxmd.com/read/35342479/the-impact-of-covid-19-infection-on-hcv-induced-thyroid-disease
#2
EDITORIAL
L Toma, A Zgura, T Isac, A Mercan-Stanciu, M Dodot, L Iliescu
Context: As we progress into the COVID-19 pandemic, it has become apparent that this infection is associated with a multitude of systemic effects, some involving the thyroid gland. The thyroid is also frequently affected in the HCV chronic infection. Objective: The objective of this study is to determine the effects of COVID-19 infection on the presence and severity of thyroid disorders associated with chronic HCV infection, at short and mid-term follow-up. Design: We prospectively evaluated patients with documented HCV- associated thyroid disease (with sustained virologic response after antiviral therapy)...
July 2021: Acta endocrinologica: the international journal of the Romanian Society of Endocrinology
https://read.qxmd.com/read/32481623/changes-in-thyroid-and-glycemic-status-and-food-intake-in-children-with-excess-weight-who-were-submitted-for-a-multi-component-school-intervention-for-16-months
#3
JOURNAL ARTICLE
Vinicius J B Martins, Andrea R Filgueiras, Viviane B P Almeida, Rúbia C S de Moraes, Ana L Sawaya
We investigated if children with excess weight who submitted to two types of intervention at school for 16 months showed improvements in thyroid and glycemic function and food intake. Children (8-11 years) with a body mass index-for-age (BMI/A) of ≥1 Z score were divided into two groups: Treatment 1 ( n = 73) involved motivation to adopt healthier lifestyle; Treatment 2 ( n = 103) involved performing weekly nutritional education, motivational, and physical activities at school. A semi-quantitative food frequency questionnaire was used...
May 28, 2020: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/32367619/prevalence-of-non-thyroidal-illness-syndrome-in-copd-exacerbation-and-effect-of-hypoxaemia-and-hypercapnia-on-thyroid-functions
#4
JOURNAL ARTICLE
Aziz Gumus, Songül Ozyurt, Neslihan Ozcelik, Bilge Yılmaz Kara
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease showing acute exacerbations during its course. Comorbidities often accompany. Non-thyroidal illness syndrome (NTIS) occurs due to the functional impairment in the hypothalamic-pituitary-thyroid axis in severe critical cases. The objective of the current study is to determine the prevalence of non-thyroidal illness syndrome among hospitalized patients due to acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and to reveal the factors affecting thyroid functions...
May 4, 2020: Clinical Respiratory Journal
https://read.qxmd.com/read/31997998/rationale-for-the-autologous-serum-skin-test-in-acute-versus-chronic-urticaria
#5
JOURNAL ARTICLE
Serkan Demirkan, Ayşe Baççıoğlu
INTRODUCTION: Autologous serum skin test (ASST) is a rapid, in-vivo clinical test to detect functional autoantibodies in patients with chronic spontaneous urticaria (CSU), but the rationale for its use in acute urticaria (AU) is unknown. AIM: To evaluate the efficacy of ASST among patients with AU or CSU. MATERIAL AND METHODS: Treatment-naïve adult (age ≥ 18 years) patients with a diagnosis of AU (< 6 weeks' duration) and CSU were enrolled prospectively in a cross-sectional study...
December 2019: Postȩpy Dermatologii i Alergologii
https://read.qxmd.com/read/31870270/thyroid-dysfunction-in-pregnant-women-with-gestational-diabetes-mellitus
#6
JOURNAL ARTICLE
Shahin Safian, Farzaneh Esna-Ashari, Shiva Borzouei
AIMS: Investigation thyroid dysfunction and autoimmunity in pregnant women with gestational diabetes mellitus. BACKGROUND: This article was written to evaluate the thyroid function and anti-thyroid peroxidase (anti- TPO) antibodies in pregnant women with gestational diabetes mellitus (GDM). METHODS: A total of 252 women with GDM and 252 healthy pregnant women were enrolled. Thyroid tests, including TSH, FreeT3, Free T4, and anti-TPO were performed for all women at 24-28 weeks of gestation...
2020: Current Diabetes Reviews
https://read.qxmd.com/read/28892954/serum-free-t-3-to-free-t-4-ratio-as-a-useful-indicator-for-differentiating-destruction-induced-thyrotoxicosis-from-graves-disease
#7
JOURNAL ARTICLE
Suman Baral, Pradeep Krishna Shrestha, Vivek Pant
INTRODUCTION: Thyrotoxicosis is a common disease encountered in Endocrine Outpatient Department (OPD). Two common causes of thyrotoxicosis are Destruction Induced Thyrotoxicosis (DIT) and Graves' Disease (GD). Differentiating DIT and GD based on clinical findings, is often not possible due to nonspecific symptoms. Thyroid scan is considered most reliable method for differentiating DIT and GD. AIM: To differentiate DIT and GD using the ratio of free triiodothyronine (fT3 ) and free thyroxine (fT4 ) thus avoiding thyroid technetium scan which is expensive and not accessible in developing countries like Nepal...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://read.qxmd.com/read/28740088/functional-correlates-of-tsh-ft3-and-ft4-in-alzheimer-disease-a-f-18-fdg-pet-ct-study
#8
JOURNAL ARTICLE
Agostino Chiaravalloti, Francesco Ursini, Alessandro Fiorentini, Gaetano Barbagallo, Alessandro Martorana, Giacomo Koch, Mario Tavolozza, Orazio Schillaci
The present study was aimed to investigate the relationships between thyroid stimulating hormone (TSH), freeT3 (fT3) and freeT4 (fT4) and brain glucose consumption as detectable by means of 2-deoxy-2-(F-18) fluoro-D-glucose (F-18 FDG) Positron Emission Tomography/Computed Tomography (PET/CT) in a selected population with Alzheimer disease (AD). We evaluated 87 subjects (37 males and 50 females, mean age 70 (±6) years old) with AD. All of them were subjected to TSH, fT3 and fT4 assay and to cerebrospinal fluid amyloid (Aβ1-42) and tau [phosphorylated-tau (p-tau) and total-tau (t-tau)] assay prior PET/CT examination...
July 24, 2017: Scientific Reports
https://read.qxmd.com/read/27809356/the-effect-of-growth-hormone-replacement-on-the-thyroid-axis-in-patients-with-hypopituitarism-in-vivo-and-ex-vivo-studies
#9
JOURNAL ARTICLE
Nigel Glynn, Helena Kenny, Leah Quisenberry, David J Halsall, Paul Cook, Tommy Kyaw Tun, John H McDermott, Diarmuid Smith, Christopher J Thompson, Donal J O'Gorman, Anita Boelen, Joaquin Lado-Abeal, Amar Agha
OBJECTIVE: Alterations in the hypothalamic-pituitary-thyroid axis have been reported following growth hormone (GH) replacement. The aim was to examine the relationship between changes in serum concentration of thyroid hormones and deiodinase activity in subcutaneous adipose tissue, before and after GH replacement. DESIGN: A prospective, observational study of patients receiving GH replacement as part of routine clinical care. PATIENTS: Twenty adult hypopituitary men...
May 2017: Clinical Endocrinology
https://read.qxmd.com/read/26167466/low-t3-syndrome-and-long-term-mortality-in-chronic-hemodialysis-patients
#10
JOURNAL ARTICLE
Stylianos Fragidis, Konstantinos Sombolos, Elias Thodis, Stylianos Panagoutsos, Euthymia Mourvati, Maria Pikilidou, Aikaterini Papagianni, Ploumis Pasadakis, Vasilios Vargemezis
AIM: To investigate the predictive value of low freeT3 for long-term mortality in chronic hemodialysis (HD) patients and explore a possible causative role of chronic inflammation. METHODS: One hundred fourteen HD patients (84 males) consecutively entered the study and were assessed for thyroid function and two established markers of inflammation, high sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6). Monthly blood samples were obtained from all patients for three consecutive months during the observation period for evaluation of thyroid function and measurement of inflammatory markers...
July 6, 2015: World Journal of Nephrology
https://read.qxmd.com/read/23252963/progesterone-therapy-increases-free-thyroxine-levels-data-from-a-randomized-placebo-controlled-12-week-hot-flush-trial
#11
RANDOMIZED CONTROLLED TRIAL
P Sathi, S Kalyan, C L Hitchcock, M Pudek, J C Prior
OBJECTIVE: Thyroid hormones and progesterone both influence core temperature, metabolism and are crucial during pregnancy. Our objective was to discover whether progesterone therapy caused changes in thyroid physiology compared with placebo. DESIGN: Post hoc analysis from a randomized (1:1) placebo-controlled 12-week trial of oral micronized progesterone (Progesterone, 300 mg/d at bedtime) for hot flushes (vasomotor symptoms, VMS) conducted in an academic medical centre...
August 2013: Clinical Endocrinology
https://read.qxmd.com/read/20825057/new-onset-addison-s-disease-presenting-as-prolonged-hyperemesis-in-early-pregnancy
#12
JOURNAL ARTICLE
Krzysztof Lewandowski, Piotr Hincz, Mariusz Grzesiak, Agata Cajdler-Łuba, Ireneusz Salata, Jan Wilczyński, Andrzej Lewiński
UNLABELLED: A 32-year-old Caucasian was admitted at 14 weeks of gestation with hypotension and weight loss. Family members noted that she appeared "tired" prior to pregnancy Past medical history included primary hypothyroidism treated with thyroxine (100 microg/day). She had a healthy daughter aged 2.5 years who had been born small for gestational age. At about 8 weeks of gestation she started to vomit several times a day. She was treated with antiemetics and intravenous fluids. Following discharge she remained nauseated, weak and lightheaded and lost about 8 kg of weight...
July 2010: Ginekologia Polska
https://read.qxmd.com/read/20533865/plasma-concentrations-of-adipocyte-fatty-acid-binding-protein-in-patients-with-cushing-s-syndrome
#13
JOURNAL ARTICLE
V Ďurovcová, J Marek, V Hána, M Matoulek, V Zikán, D Haluzíková, P Kaválková, Z Lacinová, M Kršek, M Haluzík
Serum adipocyte fatty acid-binding protein (FABP-4) concentrations are linked to human obesity and other features of metabolic syndrome. Patients with Cushing´s syndrome (CS) develop numerous features of metabolic syndrome due to chronic cortisol excess. Here we tested the hypothesis that chronically increased cortisol levels in CS patients may alter circulating levels of FABP-4. Fourteen patients with CS, 19 patients with simple obesity (OB) and 36 healthy control subjects (C) were included in the study. Serum FABP-4 concentrations were significantly higher in both CS and OB patients relative to C group, but they did not differ between CS and OB groups...
2010: Physiological Research
https://read.qxmd.com/read/19826182/experimental-hypothyroidism-increases-content-of-collagen-and-glycosaminoglycans-in-the-heart
#14
JOURNAL ARTICLE
J Drobnik, J Ciosek, D Slotwinska, B Stempniak, D Zukowska, A Marczynski, D Tosik, H Bartel, R Dabrowski, A Szczepanowska
The connective tissue matrix of the heart remains under regulatory influence of the thyroid hormones. Some conflicting data describe the connective tissue changes in subjects with thyroid gland disorders. The aim of the study was to assess the changes of the connective tissue accumulation in the heart of rats in the state of hypothyroidism and to answer the question whether TSH is involved in mechanism of the observed phenomena. Hypothyroidism in rats was induced by methylotiouracil treatment or by thyreoidectomy...
September 2009: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
https://read.qxmd.com/read/17437515/quantitative-measurement-of-thyroid-blood-flow-for-differentiation-of-painless-thyroiditis-from-graves-disease
#15
JOURNAL ARTICLE
Hisashi Ota, Nobuyuki Amino, Shinji Morita, Kaoru Kobayashi, Sumihisa Kubota, Shuji Fukata, Naohisa Kamiyama, Akira Miyauchi
OBJECTIVE: Differentiation between destruction-induced thyrotoxicosis and Graves' thyrotoxicosis is important for selection of proper therapy. It is, however, often difficult to make this distinction without measurement of radioactive iodine uptake. We investigated the possibility that assessment of thyroid blood flow would allow differentiation between the two entities. PATIENTS AND MEASUREMENTS: One hundred and fourteen untreated patients with thyrotoxicosis (56 Graves' disease, 28 painless thyroiditis, 30 subacute thyroiditis) and 25 normal controls were examined...
July 2007: Clinical Endocrinology
https://read.qxmd.com/read/16541206/age-related-differences-in-hormonal-and-nutritional-impact-on-lean-anorexia-nervosa-bone-turnover-uncoupling
#16
JOURNAL ARTICLE
B Galusca, C Bossu, N Germain, M Kadem, D Frere, M H Lafage-Proust, F Lang, B Estour
INTRODUCTION: In anorexia nervosa (AN) patients osteoporosis occurs within a framework of multiple hormonal abnormalities as a result of bone turnover uncoupling, with decreased bone formation and increased bone resorption. The aim of study was to evaluate the hormonal and nutritional relationships with both of these bone remodeling compartments and their eventual modifications with age. PATIENTS AND MEASUREMENTS: In a cohort of 115 AN patients (mean BMI:14.6 kg/m2) that included 60 mature adolescents (age: 15...
2006: Osteoporosis International
https://read.qxmd.com/read/15244214/relation-between-helicobacter-pylori-infection-thyroid-hormone-levels-and-cardiovascular-risk-factors-on-blood-donors
#17
JOURNAL ARTICLE
John K Triantafillidis, Dimitrios Georgakopoulos, Aristofanis Gikas, Emmanuel Merikas, George Peros, Kyriaki Sofroniadou, Petros Cheracakis, Maria Sklavaina, Georgios Tzanidis, Evangelia Konstantellou
The aim of this study was to assess the relationship between Helicobacter pylori (Hp) infection, serum thyroid hormone levels and certain cardiovascular risk factors in normal volunteers. In 110 blood donors (85 men, 25 women, aged 35.6 +/- 9.76) the serum levels of IgG antibodies against Hp were estimated using a sensitive immunoassay. Serum estimation of T3, T4, TSH, FT3, FT4, thyroid (microsomial) autoantibodies, C-Reactive-Protein, a1-acid-glycoprotein, vitamin B12, folic acid, cholesterol, triglycerides, total lipids, HDL, LDL, and antibodies against hepatitis A, was also carried-out...
December 2003: Hepato-gastroenterology
https://read.qxmd.com/read/10657535/thyrotropin-releasing-hormone-induced-gh-release-after-cocaine-withdrawal-in-cocaine-addicts
#18
RANDOMIZED CONTROLLED TRIAL
P P Vescovi, A Pezzarossa
During cocaine addiction the hypothalamus-pituitary axis is widely affected and a blunted response of thyroid stimulating hormone (TSH) to thyroid releasing hormone (TRH) consistent with a hyperthyroid state has been observed. Since the thyroid status can affect the release of growth hormone (GH) the authors evaluated TSH and GH responses to TRH in cocaine addicts at the time of drug withdrawal and 30 days after. Twenty-six male cocaine addicts and 11 healthy male control subjects agreed to participate in the study...
December 1999: Neuropeptides
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