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https://www.readbyqxmd.com/read/28301583/correction-cardiovascular-variability-analysis-and-baroreflex-estimation-in-patients-with-type-2-diabetes-in-absence-of-any-manifest-neuropathy
#1
Sílvia Cristina Garcia de Moura-Tonello, Alberto Porta, Andrea Marchi, Alessandra de Almeida Fagundes, Cristina de Oliveira Francisco, Patrícia Rehder-Santos, Juliana Cristina Milan-Mattos, Rodrigo Polaquini Simões, Mariana de Oliveira Gois, Aparecida Maria Catai
[This corrects the article DOI: 10.1371/journal.pone.0148903.].
2017: PloS One
https://www.readbyqxmd.com/read/28286774/orthostatic-intolerance-and-postural-orthostatic-tachycardia-syndrome-in-joint-hypermobility-syndrome-ehlers-danlos-syndrome-hypermobility-type-neurovegetative-dysregulation-or-autonomic-failure
#2
Claudia Celletti, Filippo Camerota, Marco Castori, Federica Censi, Laura Gioffrè, Giovanni Calcagnini, Stefano Strano
Background. Joint hypermobility syndrome/Ehlers-Danlos syndrome, hypermobility type (JHS/EDS-HT), is a hereditary connective tissue disorder mainly characterized by generalized joint hypermobility, skin texture abnormalities, and visceral and vascular dysfunctions, also comprising symptoms of autonomic dysfunction. This study aims to further evaluate cardiovascular autonomic involvement in JHS/EDS-HT by a battery of functional tests. Methods. The response to cardiovascular reflex tests comprising deep breathing, Valsalva maneuver, 30/15 ratio, handgrip test, and head-up tilt test was studied in 35 JHS/EDS-HT adults...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28280470/acute-effect-of-central-administration-of-urotensin-ii-on-baroreflex-and-blood-pressure-in-conscious-normotensive-rabbits
#3
Kyungjoon Lim, Yusuke Sata, Kristy L Jackson, Sandra L Burke, Geoffrey A Head
In the present study, we examined the effects of central administration of Urotensin II on blood pressure, heart rate, and baroreceptor heart rate reflexes in conscious normotensive rabbits. Preliminary operations were undertaken to implant a balloon cuff on the inferior vena cava for baroreflex assessments and to implant cannula into the lateral and fourth ventricle. After 2 weeks of recovery cumulative dose response curves to Urotensin II (10, 100 ng, 1, 10, and 100 μg) given into the ventricles, or Ringer's solution as a vehicle were performed on separate days...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28280382/retention-of-finger-blood-flow-against-postural-change-as-an-indicator-of-successful-sympathetic-block-in-the-upper-limb
#4
Toshihiko Nakatani, Tatsuya Hashimoto, Ichiro Sutou, Yoji Saito
BACKGROUND: Sympathetic block in the upper limb has diagnostic, therapeutic and prognostic utility for disorders in the upper extremity that are associated with sympathetic disturbances. Increased skin temperature and decreased sweating are used to identify the adequacy of sympathetic block in the upper limb after stellate ganglion block (SGB). Baroreflexes elicited by postural change induce a reduction in peripheral blood flow by causing sympathetic vasoconstriction. We hypothesized that sympathetic block in the upper limb reduces the decrease in finger blood flow caused by baroreflexes stimulated by postural change from the supine to long sitting position...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28274940/aortic-depressor-nerve-stimulation-does-not-impede-dynamic-characteristics-of-the-carotid-sinus-baroreflex-in-normotensive-or-spontaneously-hypertensive-rats
#5
Toru Kawada, Michael J Turner, Shuji Shimizu, Masafumi Fukumitsu, Atsunori Kamiya, Masaru Sugimachi
Recent clinical trials in patients with drug-resistant hypertension indicate that electrical activation of the carotid sinus baroreflex (baroreflex activation therapy) can reduce arterial pressure (AP) for more than a year. To examine whether the electrical stimulation from one baroreflex system impedes normal short-term AP regulation via another unstimulated baroreflex system, we electrically stimulated the left aortic depressor nerve (ADN) while estimating the dynamic characteristics of the carotid sinus baroreflex in anesthetized normotensive Wistar-Kyoto (WKY, n=8) rats and spontaneously hypertensive rats (SHR, n=7)...
March 8, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28268929/cardiovascular-interactions-assessed-via-conditional-joint-transfer-entropy-in-patients-developing-atrial-fibrillation-after-coronary-artery-bypass-graft-surgery
#6
Vlasta Bari, Marco Ranucci, Andrea Marchi, Beatrice De Maria, Valeria Pistuddi, Alberto Porta
Assigned the universe of knowledge Ω as composed by one target and two exogenous signals, the conditional joint transfer entropy (CJTE), assessing the amount of information jointly transferred from the two sources to the target that can be uniquely linked to one of the two sources, was found useful to study cardiovascular control. We propose the assessment of CJTE from systolic arterial pressure (SAP) and respiration (R) to heart period (HP) conditioned on R (CJTESAP, R→HP|R) along the baroreflex, and from HP and R to SAP conditioned on R (CJTEHP, R→SAP|R) along the feedforward mechanical pathway, in 134 patients undergoing coronary artery bypass graft surgery before (PRE) and after (POST) the induction of general anesthesia...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268875/a-model-based-method-to-measure-baroreflex-sensitivity
#7
Yu Meng, Zhipei Huang, Jiangkang Wu, Xinxia Cai
This paper proposes a model-based method to quantitatively measure baroreflex sensitivity in autonomic nervous regulation of cardiovascular system. The method measures the continuous blood pressure and heart rate in orthostatic scenario, models dynamics of the baroreflex firing rate, solves parameters by optimization of measured blood pressure and heart rate variations. With this model, we can get the baroreflx sensitivity (BRS) inner indicators to evaluate the status of the autonomic nervous regulation system...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267133/recent-advances-in-the-pathophysiology-of-arterial-hypertension-potential-implications-for-clinical-practice
#8
Dagmara Hering, Andrzej Trzebski, Krzysztof Narkiewicz
Hypertension remains a major and growing public health problem associated with the greatest proportion of global cardiovascular (CV) morbidity and mortality. Although numerous factors contribute to poor blood pressure (BP) control and pseudo-resistance (i.e. unawareness, life-style habits, non-adherence to medication, insufficient treatment, drug-induced hypertension, undiagnosed secondary causes etc.), it is reported that true resistant hypertension (RH) is found in 10.1 % of patients treated for elevated BP...
March 1, 2017: Pol Arch Intern Med
https://www.readbyqxmd.com/read/28263183/complexity-of-cardiovascular-rhythms-during-head-up-tilt-test-by-entropy-of-patterns
#9
Dorota Wejer, Beata Graff, Danuta Makowiec, Szymon Budrejko, Zbiginiew Struzik
The head-up tilt (HUT) test, which provokes transient dynamical alterations in the regulation of cardiovascular system, provides insights into complex organization of this system. Based on signals with heart period intervals (RR-intervals) and/or systolic blood pressure (SBP), differences in the cardiovascular regulation between vasovagal patients (VVS) and the healthy people group (CG) are investigated. Short-term relations among signal data represented symbolically by three-beat patterns allow to qualify and quantify the complexity of the cardiovascular regulation by Shannon entropy...
March 6, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28261799/baroreflex-control-of-renal-sympathetic-nerve-activity-in-early-heart-failure-assessed-by-the-sequence-method
#10
Renata Maria Lataro, Luiz Eduardo Virgilio Silva, Carlos Alberto Aguiar Silva, Helio Cesar Salgado, Rubens Fazan
In heart failure (HF), the reflex control of the heart rate is known to be markedly impaired; however, the baroreceptor control of the sympathetic drive remains under debate. Applying the sequence method to a series of arterial pressure (AP) and renal sympathetic nerve activity (RSNA), we demonstrated a clear dysfunction in the baroreflex control of sympathetic activity in rats with early HF. We analysed the baroreflex control of the sympathetic drive using three different approaches: AP vs. RSNA curve, cross-spectral analysis and sequence method between AP and RSNA...
March 6, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28245992/overt-and-subclinical-baroreflex-dysfunction-following-bilateral-carotid-body-tumor-resection-pathophysiology-diagnosis-and-implications-for-management
#11
REVIEW
Michael G Z Ghali, Visish M Srinivasan, Ehab Hanna, Franco DeMonte
Carotid body paragangliomas are rare, usually benign, tumors arising from glomus cells of the carotid body. Bilateral involvement is present in ∼5% of sporadic cases and up to one-third of familial cases. In the majority of patients undergoing bilateral resection of carotid body tumors (CBTs), a condition known as baroreflex failure syndrome (BFS) develops following resection of the second tumor characterized by headache, anxiety, emotional lability, orthostatic lightheadedness, hypertension, and tachycardia...
February 25, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28245206/cerebrovascular-and-cardiovascular-variability-interactions-investigated-through-conditional-joint-transfer-entropy-in-subjects-prone-to-postural-syncope
#12
Vlasta Bari, Beatrice De Maria, Claudio Enrico Mazzucco, Gianluca Rossato, Davide Tonon, Giandomenico Nollo, Luca Faes, Alberto Porta
A model-based conditional transfer entropy approach was exploited to quantify the information transfer in cerebrovascular (CBV) and cardiovascular (CV) systems in subjects prone to develop postural syncope. Spontaneous beat-to-beat variations of mean cerebral blood flow velocity (MCBFV) derived from a transcranial Doppler device, heart period (HP) derived from surface electrocardiogram, mean arterial pressure (MAP) and systolic arterial pressure (SAP) derived from finger plethysmographic arterial pressure device were monitored at rest in supine position (REST) and during 60° head-up tilt (TILT) in 13 individuals (age mean±standard deviation: 28±9 years, min-max range: 18-44 years, 5 males) with a history of recurrent episodes of syncope (SYNC) and in 13 age- and gender-matched controls (NonSYNC)...
February 28, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28243928/pathophysiology-and-potential-non-pharmacologic-treatments-of-obesity-or-kidney-disease-associated-refractory-hypertension
#13
REVIEW
Thierry H Le Jemtel, William Richardson, Rohan Samson, Abhishek Jaiswal, Suzanne Oparil
PURPOSE OF REVIEW: The review assesses the role of non-pharmacologic therapy for obesity and chronic kidney disease (CKD) associated refractory hypertension (rf HTN). RECENT FINDINGS: Hypertensive patients with markedly heightened sympathetic nervous system (SNS) activity are prone to develop refractory hypertension (rfHTN). Patients with obesity and chronic kidney disease (CKD)-associated HTN have particularly heightened SNS activity and are at high risk of rfHTN...
February 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28239335/central-and-peripheral-effects-of-urotensin-ii-and-urotensin-ii-related-peptides-on-cardiac-baroreflex-sensitivity-in-trout
#14
Frédéric Lancien, Gilmer Vanegas, Jérôme Leprince, Hubert Vaudry, Jean-Claude Le Mével
The baroreflex response is an essential component of the cardiovascular regulation that buffers abrupt changes in blood pressure to maintain homeostasis. Urotensin II (UII) and its receptor UT are present in the brain and in peripheral cardiovascular tissues of fish and mammals. Intracerebroventricular (ICV) injection of UII in these vertebrates provokes hypertension and tachycardia, suggesting that the cardio-inhibitory baroreflex response is impaired. Since nothing is known about the effect of UII on the cardiac baroreflex sensitivity (BRS), we decided to clarify the changes in spontaneous BRS using a cross spectral analysis technique of systolic blood pressure (SBP) and R-R interval variabilities after ICV and intra-arterial (IA) injections of trout UII in the unanesthetized trout...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28238048/dynamics-of-the-rr-interval-versus-blood-pressure-relationship-at-exercise-onset-in-humans
#15
Aurélien Bringard, Alessandra Adami, Nazzareno Fagoni, Timothée Fontolliet, Frédéric Lador, Christian Moia, Enrico Tam, Guido Ferretti
PURPOSE: The dynamics of the postulated phenomenon of exercise baroreflex resetting is poorly understood, but can be investigated using closed-loop procedures. To shed light on some mechanisms and temporal relationships participating in the resetting process, we studied the time course of the relationship between the R-R interval (RRi) and arterial pressure with a closed-loop approach. METHODS: On ten young volunteers at rest and during light exercise in supine and upright position, we continuously determined, on single-beat basis, RRi (electrocardiography), and arterial pressure (non-invasive finger pressure cuff)...
February 25, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28227134/cardiovascular-interactions-assessed-via-conditional-joint-transfer-entropy-in-patients-developing-atrial-fibrillation-after-coronary-artery-bypass-graft-surgery
#16
Vlasta Bari, Marco Ranucci, Andrea Marchi, Beatrice De Maria, Valeria Pistuddi, Alberto Porta, Vlasta Bari, Marco Ranucci, Andrea Marchi, Beatrice De Maria, Valeria Pistuddi, Alberto Porta, Vlasta Bari, Andrea Marchi, Alberto Porta, Valeria Pistuddi, Beatrice De Maria, Marco Ranucci
Assigned the universe of knowledge Ω as composed by one target and two exogenous signals, the conditional joint transfer entropy (CJTE), assessing the amount of information jointly transferred from the two sources to the target that can be uniquely linked to one of the two sources, was found useful to study cardiovascular control. We propose the assessment of CJTE from systolic arterial pressure (SAP) and respiration (R) to heart period (HP) conditioned on R (CJTESAP, R→HP|R) along the baroreflex, and from HP and R to SAP conditioned on R (CJTEHP, R→SAP|R) along the feedforward mechanical pathway, in 134 patients undergoing coronary artery bypass graft surgery before (PRE) and after (POST) the induction of general anesthesia...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227073/a-model-based-method-to-measure-baroreflex-sensitivity
#17
Yu Meng, Zhipei Huang, Jiangkang Wu, Xinxia Cai, Yu Meng, Zhipei Huang, Jiangkang Wu, Xinxia Cai, Yu Meng, Jiangkang Wu, Xinxia Cai, Zhipei Huang
This paper proposes a model-based method to quantitatively measure baroreflex sensitivity in autonomic nervous regulation of cardiovascular system. The method measures the continuous blood pressure and heart rate in orthostatic scenario, models dynamics of the baroreflex firing rate, solves parameters by optimization of measured blood pressure and heart rate variations. With this model, we can get the baroreflx sensitivity (BRS) inner indicators to evaluate the status of the autonomic nervous regulation system...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225018/choline-ameliorates-cardiovascular-damage-by-improving-vagal-activity-and-inhibiting-the-inflammatory-response-in-spontaneously-hypertensive-rats
#18
Longzhu Liu, Yi Lu, Xueyuan Bi, Man Xu, Xiaojiang Yu, Runqing Xue, Xi He, Weijin Zang
Autonomic dysfunction and abnormal immunity lead to systemic inflammatory responses, which result in cardiovascular damage in hypertension. The aim of this report was to investigate the effects of choline on cardiovascular damage in hypertension. Eight-week-old male spontaneously hypertensive rats (SHRs) and Wistar-Kyoto rats were intraperitoneally injected with choline or vehicle (8 mg/kg/day). After 8 weeks, choline restored the cardiac function of the SHRs, as evidenced by decreased heart rate, systolic blood pressure, left ventricle systolic pressure, and ±dp/dtmax and increased ejection fraction and fractional shortening...
February 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28219104/captopril-does-not-potentiate-post-exercise-hypotension-a-randomized-crossover-study
#19
Andréia Cristiane Carrenho Queiroz, Julio Cesar Silva Sousa, Natan Daniel Silva, Eleonora Tobaldini, Katia Coelho Ortega, Edilamar Menezes de Oliveira, Patricia Chakur Brum, Nicola Montano, Decio Mion, Taís Tinucci, Claudia Lucia de Moraes Forjaz
To evaluate whether captopril (3×50 mg/day) potentiates post-resistance exercise hypotension (PREH) in hypertensives (HT), 12 HT men received captopril and placebo for 4 weeks each in a double-blinded, randomized-crossover design. On each therapy, subjects underwent 2 sessions: Control (C - rest) and Resistance Exercise (RE - 7 exercises, 3 sets to moderate fatigue, 50% of 1 RM -repetition maximum). Measurements were taken before and after 30-60 min (Post1) and 7 h (Post2), and ambulatory blood pressure (BP) was monitored for 24 h...
February 20, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28205011/neural-control-of-blood-pressure-in-women-differences-according-to-age
#20
Ana B Peinado, Ronee E Harvey, Emma C Hart, Nisha Charkoudian, Timothy B Curry, Wayne T Nicholson, B Gunnar Wallin, Michael J Joyner, Jill N Barnes
PURPOSE: The blood pressure "error signal" represents the difference between an individual's mean diastolic blood pressure and the diastolic blood pressure at which 50% of cardiac cycles are associated with a muscle sympathetic nerve activity burst (the "T50"). In this study we evaluated whether T50 and the error signal related to the extent of change in blood pressure during autonomic blockade in young and older women, to study potential differences in sympathetic neural mechanisms regulating blood pressure before and after menopause...
February 16, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
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