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https://www.readbyqxmd.com/read/28324761/chocolate-consumption-and-risk-of-stroke-among-men-and-women-a-large-population-based-prospective-cohort-study
#1
Jia-Yi Dong, Hiroyasu Iso, Kazumasa Yamagishi, Norie Sawada, Shoichiro Tsugane
BACKGROUND AND AIMS: Chocolate consumption may have a beneficial effect on cardiovascular health, but evidence from prospective cohort studies is still limited. We aimed to examine the prospective associations between chocolate consumption and risk of stroke among men and women in a large population-based cohort. METHODS: A total of 38,182 men and 46,415 women aged 44-76 years, and free of cardiovascular disease, diabetes, and cancer at baseline in 1995 and 1998, were followed up until the end of 2009 and 2010, respectively...
March 4, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28303537/concentrations-of-trace-metals-in-tissues-of-chionoecetes-crabs-chionoecetes-japonicus-and-chionoecetes-opilio-caught-from-the-east-japan-sea-waters-and-potential-risk-assessment
#2
Dong-Woon Hwang, Minkyu Choi, In-Seok Lee, Kil-Bo Shim, Tae-Hoon Kim
The concentrations of trace metals (As, Cd, Co, Cu, Fe, Hg, Pb, and Zn) were measured in muscle and hepatopancreas of two Chionoecetes crabs (Chionoecetes japonicus and C. opilio) caught from the East/Japan Sea (EJS) in order to assess the potential health risk by the consumption of deep sea crabs. The highest metal concentrations in muscle and hepatopancreas were As and Fe, respectively, while the lowest metal concentration in two tissues was Pb. The mean concentrations of Cd, Co, Cu, Fe, and Pb in Chionoecetes crabs were one or two orders of magnitude higher in hepatopancreas than in muscles...
March 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28294086/school-lunches-in-japan-their-contribution-to-healthier-nutrient-intake-among-elementary-school-and-junior-high-school-children
#3
Keiko Asakura, Satoshi Sasaki
OBJECTIVE: The role of school lunches in diet quality has not been well studied. Here, we aimed to determine the contribution of school lunches to overall nutrient intake in Japanese schoolchildren. DESIGN: The study was conducted nationwide under a cross-sectional design. A non-consecutive, three-day diet record was performed on two school days and a non-school day separately. The prevalence of inadequate nutrient intake was estimated for intakes on one of the school days and the non-school day, and for daily habitual intake estimated by the best-power method...
March 15, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28292660/prevalence-antimicrobial-resistance-and-multiple-locus-variable-number-tandem-repeat-analysis-profiles-of-diarrheagenic-escherichia-coli-isolated-from-different-retail-foods
#4
Lili Wang, Hiromi Nakamura, Eriko Kage-Nakadai, Yukiko Hara-Kudo, Yoshikazu Nishikawa
Diarrheagenic E. coli (DEC) isolates were recovered from local retail markets and the Osaka Municipal Central Wholesale Market in Japan. Retail food samples were collected for analysis in Osaka Japan from 2005 to 2008 and consisted of 32 beef, 28 pork, 20 poultry, 136 fish, 66 fruits and vegetables and 51 ready-to-eat (RTE) food samples. A total of 82 DEC strains were recovered from 64 (19%) food samples with the highest prevalence in poultry (100%, 20/20), followed by pork (54%, 15/28), beef (28%, 9/32), fruits and vegetables (12%, 8/66), fish (6...
March 7, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28290098/cardiac-sympathetic-nervous-system-imaging-with-123-i-meta-iodobenzylguanidine-perspectives-from-japan-and-europe
#5
Kenichi Nakajima, Arthur J H A Scholte, Tomoaki Nakata, Aukelien C Dimitriu-Leen, Taishiro Chikamori, João V Vitola, Keiichiro Yoshinaga
Cardiac sympathetic nervous system dysfunction is closely associated with risk of serious cardiac events in patients with heart failure (HF), including HF progression, pump-failure death, and sudden cardiac death by lethal ventricular arrhythmia. For cardiac sympathetic nervous system imaging, (123)I-meta-iodobenzylguanidine ((123)I-MIBG) was approved by the Japanese Ministry of Health, Labour and Welfare in 1992 and has therefore been widely used since in clinical settings. (123)I-MIBG was also later approved by the Food and Drug Administration (FDA) in the United States of America (USA) and it was expected to achieve broad acceptance...
March 13, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28285847/japanese-guidelines-for-food-allergy-2017
#6
REVIEW
Motohiro Ebisawa, Komei Ito, Takao Fujisawa
Five years have passed since the Japanese Pediatric Guideline for Food Allergy (JPGFA) was first revised in 2011 from its original version. As many scientific papers related to food allergy have been published during the last 5 years, the second major revision of the JPGFA was carried out in 2016. In this guideline, food allergies are generally classified into four clinical types: (1) neonatal and infantile gastrointestinal allergy, (2) infantile atopic dermatitis associated with food allergy, (3) immediate-type of food allergy (urticaria, anaphylaxis, etc...
March 9, 2017: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/28273392/surfing-parameter-hyperspaces-under-climate-change-scenarios-to-design-future-rice-ideotypes
#7
Livia Paleari, Ermes Movedi, Giovanni Cappelli, Lloyd T Wilson, Roberto Confalonieri
Growing food crops to meet global demand and the search for more sustainable cropping systems are increasing the need for new cultivars in key production areas. This study presents the identification of rice traits putatively producing the largest yield benefits in five areas that markedly differ in terms of environmental conditions in the Philippines, India, China, Japan and Italy. The ecophysiological model WARM and sensitivity analysis techniques were used to evaluate phenotypic traits involved with light interception, photosynthetic efficiency, tolerance to abiotic stressors, resistance to fungal pathogens and grain quality...
March 8, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28270897/determinants-of-glycated-hemoglobin-in-subjects-with-impaired-glucose-tolerance-subanalysis-of-the-japan-diabetes-prevention-program
#8
Naoki Sakane, Juichi Sato, Kazuyo Tsushita, Satoru Tsujii, Kazuhiko Kotani, Makoto Tominaga, Shoji Kawazu, Yuzo Sato, Takeshi Usui, Isao Kamae, Toshihide Yoshida, Yutaka Kiyohara, Shigeaki Sato, Kokoro Tsuzaki, Shinsuke Nirengi, Kaoru Takahashi, Hideshi Kuzuya, Jdpp Research Group
BACKGROUND: Limited evidence is available about the relationship of lifestyle factors with glycated hemoglobin (HbA1c) in subjects with impaired glucose tolerance. The aim of study was to identify such determinant factors of HbA1c in subjects with impaired glucose tolerance. METHODS: This cross-sectional study included 121 men and 124 women with impaired glucose tolerance, who were diagnosed based on a 75-g oral glucose tolerance test. Demographic and biochemical parameters, including the body mass index (BMI), fasting plasma glucose (FPG), 2-h post-load glucose (2-h PG), and HbA1c, were measured...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28264497/nattokinase-an-oral-antithrombotic-agent-for-the-prevention-of-cardiovascular-disease
#9
REVIEW
Yunqi Weng, Jian Yao, Sawyer Sparks, Kevin Yueju Wang
Natto, a fermented soybean product, has been consumed as a traditional food in Japan for thousands of years. Nattokinase (NK), a potent blood-clot dissolving protein used for the treatment of cardiovascular diseases, is produced by the bacterium Bacillus subtilis during the fermentation of soybeans to produce Natto. NK has been extensively studied in Japan, Korea, and China. Recently, the fibrinolytic (anti-clotting) capacity of NK has been recognized by Western medicine. The National Science Foundation in the United States has investigated and evaluated the safety of NK...
February 28, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28260734/validation-study-on-a-method-for-simultaneous-quantification-of-elements-in-mineral-water-and-surveillance-of-element-concentrations
#10
Yohei Kataoka, Takahiro Watanabe, Rieko Matsuda, Tomoko Hayashi, Hiroshi Akiyama, Reiko Teshima
A validation study was performed on the Japanese official method to determine several elements (B, Cr, Mn, Cu, Zn, As, Se, Cd, Ba, Pb) in mineral water simultaneously using ICP-MS. The trueness, repeatability and reproducibility of the method were estimated to be in the ranges of 95-106, 0.2-1.4 and 0.4-4.2%, respectively. The values of every performance parameter fulfilled the requirements in the guidelines announced by the Ministry of Health, Labour, and Welfare of Japan, and the validity of the method was confirmed...
2017: Shokuhin Eiseigaku Zasshi. Journal of the Food Hygienic Society of Japan
https://www.readbyqxmd.com/read/28260733/survey-of-nitrate-ion-concentrations-in-vegetables-cultivated-in-plant-factories-comparison-with-open-culture-vegetables
#11
COMPARATIVE STUDY
Yuka Oka, Izumi Hirayama, Mitsuhide Yoshikawa, Tomoko Yokoyama, Kenji Iida, Katsushi Iwakoshi, Ayana Suzuki, Midori Yanagihara, Yukino Segawa, Sonomi Kukimoto, Humika Hamada, Satomi Matsuzawa, Setsuko Tabata, Takeo Sasamoto
A survey of nitrate-ion concentrations in plant-factory-cultured leafy vegetables was conducted. 344 samples of twenty-one varieties of raw leafy vegetables were examined using HPLC. The nitrate-ion concentrations in plant-factory-cultured leafy vegetables were found to be LOD-6,800 mg/kg. Furthermore, the average concentration values varied among different leafy vegetables. The average values for plant-factory-cultured leafy vegetables were higher than those of open-cultured leafy vegetables reported in previous studies, such as the values listed in the Standard Tables of Food Composition in Japan- 2015 - (Seventh revised edition)...
2017: Shokuhin Eiseigaku Zasshi. Journal of the Food Hygienic Society of Japan
https://www.readbyqxmd.com/read/28260732/detection-of-histamine-in-fish-and-fishery-products-in-osaka-prefecture-fiscal-2015-report
#12
Kaoru Awazu, Satoshi Takatori, Sachiko Kakimoto, Chie Nomura, Atsushi Masayama, Mizuka Yamaguchi, You Kakimoto, Keiji Kajimura
Histamine food poisoning is caused by ingestion of spoiled fish containing high levels of histamine. This paper reports cases in which histamine was detected in Osaka prefecture in fiscal year 2015 in a survey of fish and fishery products on the market and the food poisoning. A suspected case of histamine food poisoning was also evaluated to investigate the cause and minimize further problems. Histamine in food was separated on SPE cartridge columns, and analyzed after derivatization with fluorescamine by means of HPLC-FL...
2017: Shokuhin Eiseigaku Zasshi. Journal of the Food Hygienic Society of Japan
https://www.readbyqxmd.com/read/28260731/surveys-of-food-intake-just-after-the-nuclear-accident-at-the-fukushima-daiichi-nuclear-power-station
#13
Sachiko Hirakawa, Nobuaki Yoshizawa, Kana Murakami, Mari Takizawa, Masaki Kawai, Osamu Sato, Shunji Takagi, Gen Suzuki
As a result of the nuclear accident at the Fukushima Daiichi nuclear power station (FDNPS) after the Great East Japan Earthquake on March 11, 2011, volatile radionuclides including iodine-131 were released into the environment and contaminated open-field vegetables, raw milk, tap water, etc. It is important for the health care of residents to correctly comprehend the level of their exposure to radioactive substances released following the accident. However, an evaluation of the internal exposure doses of residents of Fukushima Prefecture as a result of the ingestion of foods, which is indicated in the report issued by United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR)1 is based on a number of assumptions...
2017: Shokuhin Eiseigaku Zasshi. Journal of the Food Hygienic Society of Japan
https://www.readbyqxmd.com/read/28260730/identification-of-alocasia-odora-kuwazuimo-in-japanese-using-pcr-method
#14
Kayo Hagino, Hisako Nakano, Motomu Shimizu, Akiko Terai, Mami Ogai, Masako Aragane, Tomohiro Abe, Takeo Sasamoto
Kuwazuimo (Alocasia odora) and shimakuwazuimo (Alocasia cucullata) are evergreen perennial plants that originated in East Asia. Although inedible, they are occasionally eaten by mistake because they resemble satoimo (Colocasia esculenta), and this has caused food poisoning in Japan. It is not easy to determine the cause of a food poisoning outbreak from the shape or chemical composition when the available sample is small. Therefore, we developed a new primer pair for PCR to identify kuwazuimo and shimakuwazuimo in small samples, based on the internal transcribed spacer (ITS) region of ribosomal DNA...
2017: Shokuhin Eiseigaku Zasshi. Journal of the Food Hygienic Society of Japan
https://www.readbyqxmd.com/read/28256076/meat-consumption-and-colorectal-cancer-risk-in-japan-the-takayama-study
#15
Keiko Wada, Shino Oba, Michiko Tsuji, Takashi Tamura, Kie Konishi, Yuko Goto, Fumi Mizuta, Sachi Koda, Akihiro Hori, Shinobu Tanabashi, Shogen Matsushita, Naoki Tokimitsu, Chisato Nagata
Compared with the abundant data from Western countries, evidence regarding meat consumption and colorectal cancer is limited in the Japanese population. We evaluated colorectal cancer risk in relation to meat consumption in a population-based prospective cohort study in Japan. Participants were 13,957 men and 16,374 women aged ≥35 years in September 1992. Meat intake, assessed with a validated food frequency questionnaire, was controlled for the total energy intake. The incidence of colorectal cancer was confirmed through regional population-based cancer registries and histological identification from colonoscopy in two main hospitals in the study area...
March 3, 2017: Cancer Science
https://www.readbyqxmd.com/read/28250868/evolution-of-genotoxicity-test-methods-in-japan
#16
Toshio Sofuni
The evolution of methods to assess genotoxicity of test compounds is thought to be one of the important subjects in The Japanese Environmental and Mutagen Society (JEMS). In 1970, the Ministry of Education of Japan (at that time) organized a research group (Organizer: Y. Tazima, National Institute of Genetics), and started a systematic research on the genotoxic effects induced by chemical substances. Considering the importance of this issue through the outcomes of the research group, JEMS was established in 1972, and President Tazima organized the 1st annual meeting in the August in Tokyo with the participation of experts in this field working in national institutes, universities and others in Japan...
2017: Genes and Environment: the Official Journal of the Japanese Environmental Mutagen Society
https://www.readbyqxmd.com/read/28247277/diagnosis-and-treatment-of-eosinophilic-esophagitis-in-clinical-practice
#17
REVIEW
Yasuhiko Abe, Yu Sasaki, Makoto Yagi, Takao Yaoita, Shoichi Nishise, Yoshiyuki Ueno
Eosinophilic esophagitis (EoE) is a chronic and abnormal Th2 type immunological response characterized by intense eosinophilic inflammation localized within the esophagus. This leads to esophageal dysfunction and remodeling accompanied by subepithelial fibrosis. Recently, EoE has been recognized as one of the major causes of dysphagia or food impaction in adults. The prevalence of EoE has been increasing over the past several decades, particularly in Western countries. EoE should be differentiated from secondary esophageal eosinophilia (EE) in gastroesophageal reflux disease (GERD) and eosinophilic gastroenteritis, involving the entire gastrointestinal tract...
April 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28244710/meal-services-after-the-great-east-japan-earthquake-at-nursery-schools-in-a-tsunami-affected-town-focus-group-observations
#18
Yukiko Amitani, Noriko Sudo, Nobuyo Tsuboyama-Kasaoka, Fumiko Ishikawa, Kazuko Sako
BACKGROUND AND OBJECTIVES: This study aimed to collect information on experiences in the Great East Japan Earthquake (hereafter, 3.11), current preparedness, and barriers to building up stockpiles in nursery schools in affected areas. Based on the needs heard from the staff, we decided what contents should be included in our manual developed with the Japan Dietetic Association. METHODS AND STUDY DESIGN: A group interview was held in September 2012. We interviewed a principal, nurses, and registered dietitians working for a public and a private nursery school in Town A...
March 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28237291/screening-test-for-radioactivity-of-self-consumption-products-in-fukushima-after-the-fukushima-dai-ichi-npp-accident-in-japan
#19
Takahiro Yamada, Mihoko Kikuchi, Daisuke Yagihashi, Shinya Yamakawa, Hidetake Ishizu, Takuya Shiina
A food inspection service system for home grown products or wild plants collected by individual consumers for self-consumption was implemented in Fukushima in Nov. 2012. About 500 NaI(Tl) scintillation spectrometers were distributed to 300 or more temporary testing laboratories which were set up in public halls or meeting places of the municipalities. The screening method for radiocaesium was adapted to the present inspection service system. The performance of the equipment under field conditions was evaluated using sampled data obtained by temporary testing laboratories...
February 23, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28236116/clinical-pharmacokinetic-and-pharmacodynamic-profile-of-lenvatinib-an-orally-active-small-molecule-multitargeted-tyrosine-kinase-inhibitor
#20
Ziad Hussein, Hitoshi Mizuo, Seiichi Hayato, Masayuki Namiki, Robert Shumaker
Lenvatinib is a multikinase inhibitor that targets vascular endothelial growth factor (VEGF) receptors 1-3, fibroblast growth factor receptors 1-4, platelet-derived growth factor receptor-alpha, and RET and KIT proto-oncogenes. Lenvatinib is approved for the treatment of radioiodine-refractory differentiated thyroid cancer in the United States (US), European Union (EU), Canada, Japan, and Switzerland. It is also approved in combination with everolimus for the treatment of advanced renal cell carcinoma following ≥1 VEGF-targeted treatment in the US and EU...
February 24, 2017: European Journal of Drug Metabolism and Pharmacokinetics
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