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https://www.readbyqxmd.com/read/27888534/early-steroid-withdrawal-results-in-improved-patient-and-graft-survival-and-lower-risk-of-post-transplant-cardiovascular-risk-profiles-a-single-center-10-year-experience
#1
Reynold Lopez-Soler, Ryan Chan, Jessica Martinolich, Lisa Park, Ashar Ata, Nikolaos Chandolias, David Conti
Long term use of steroids results in predictable secondary effects that can lead to increased morbidity and mortality. In this study, we present 10 years' worth of data of early steroid withdrawal (ESW) immunosuppression consisting of Mycophenolate, Sirolimus, and Tacrolimus. From 2003 to 2013, 563 kidney transplant recipients were weaned off steroids prior to discharge. We compared outcomes with that of our 65 historical controls maintained on steroids. We analyzed graft and patient survival and determined the incidence of steroid-related comorbidities such as hypertension, hypercholesterolemia, diabetes, coronary artery disease, and weight gain...
November 26, 2016: Clinical Transplantation
https://www.readbyqxmd.com/read/27723374/comparison-of-clinical-efficacy-among-endoscopy-assisted-radio-frequency-ablation-extracorporeal-shockwaves-and-eccentric-exercises-in-treatment-of-insertional-achilles-tendinosis
#2
Min Wei, Yujie Liu, Zhongli Li, Zhigang Wang
BACKGROUND: We sought to compare clinical efficacy among endoscopy-assisted radio-frequency ablation under local anesthesia, extracorporeal shockwaves (ESWs), and eccentric exercises in treating insertional Achilles tendinosis. METHODS: In this retrospective study, 78 patients diagnosed as having unilateral insertional Achilles tendinosis were enrolled. These participants underwent endoscopy-assisted radio-frequency ablation, ESWs, and eccentric calf muscle exercises between March 1, 2006, and February 28, 2011...
October 10, 2016: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/27679772/self-worth-and-psychological-adjustment-of-obese-children-an-analysis-through-the-draw-a-person
#3
Giuseppe Scimeca, Amelia Alborghetti, Antonio Bruno, Giulia Maria Troili, Gianluca Pandolfo, Maria Rosaria Anna Muscatello, Rocco Antonio Zoccali
AIM: To investigate psychopathological correlates of child obesity via the Draw-A-Person test (DAP). METHODS: The participants were 50 children with a mean age of 9.74 years. Body mass index (BMI) was used as a measure of body fat. Children were divided into normal (n = 17), overweight (n = 14) and obese (n = 19). Two qualitative methods of scoring the DAP based on an integrative approach were used to assess self-concept (ESW) and overall level of children's adjustment (EAC)...
September 22, 2016: World Journal of Psychiatry
https://www.readbyqxmd.com/read/27619896/understanding-barriers-to-optimal-cleaning-and-disinfection-in-hospitals-a-knowledge-attitudes-and-practices-survey-of-environmental-services-workers
#4
Daniel A Bernstein, Elizabeth Salsgiver, Matthew S Simon, William Greendyke, Daniel P Eiras, Masahiro Ito, Dean A Caruso, Timothy M Woodward, Odette T Perriel, Lisa Saiman, E Yoko Furuya, David P Calfee
In this study, we used an online survey to assess knowledge, attitudes, and practices related to environmental cleaning and other infection prevention strategies among environmental services workers (ESWs) at 5 hospitals. Our findings suggest that ESWs could benefit from additional education and feedback as well as new strategies to address workflow challenges. Infect Control Hosp Epidemiol 2016;1492-1495.
December 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27589545/extensive-use-of-vasodilator-agents-and-functional-echocardiography-to-monitor-extremely-low-birth-weight-infants-in-japan
#5
M Miyata, K Toyoshima, H Yoda, M Murase, H Kawato, K Yamamoto, K Tanaka, M Kotani, M Kobayashi
National surveys were conducted in Japan to assess the current practices for circulatory management of extremely-low-birth-weight infants (ELBWIs) in acute phases. Approximately 80 and 100 institutions were surveyed in 2006 and 2011, respectively. Echocardiography was identified as an important diagnostic tool at 95% of the surveyed institutions. Furthermore, 74% of the institutions survey in 2011 used vasodilator agents. In 2011, the mean velocity of circumferential fiber shortening (mVcfc) and left ventricular end-systolic wall stress (ESWS) were used by 60% of the surveyed institutions to evaluate the relationship between afterload of the left ventricle and left ventricular contractility...
September 16, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27515217/prostaglandin-e2-and-connexin-43-crosstalk-in-the-osteogenesis-induced-by-extracorporeal-shockwave
#6
Youbin Chen, Jiankun Xu, Haojie Liao, Zebin Ma, Yuantao Zhang, Hongjiang Chen, Zhonglian Huang, Jun Hu
As a type of mechanical stimulation, extracorporeal shockwave (ESW) has been widely used in the clinic to treat bone fracture delayed union and non-unions. A large number of studies have shown beneficial effects of ESW in promoting fracture healing by inducing bone regeneration; however, the underlying mechanisms remain unclear. ESW has been shown to induce the production of prostaglandin E2 (PGE2), which is essential for gap junction intercellular communication in response to mechanical stress. Among the 19 known gap junction subunits, connexin43 (Cx43) is the most prevalent for mediating the response of mechanical stress...
September 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/27455287/preparation-of-chito-oligomers-by-hydrolysis-of-chitosan-in-the-presence-of-zeolite-as-adsorbent
#7
Khalid A Ibrahim, Bassam I El-Eswed, Khaleel A Abu-Sbeih, Tawfeeq A Arafat, Mahmoud M H Al Omari, Fouad H Darras, Adnan A Badwan
An increasing interest has recently been shown to use chitin/chitosan oligomers (chito-oligomers) in medicine and food fields because they are not only water-soluble, nontoxic, and biocompatible materials, but they also exhibit numerous biological properties, including antibacterial, antifungal, and antitumor activities, as well as immuno-enhancing effects on animals. Conventional depolymerization methods of chitosan to chito-oligomers are either chemical by acid-hydrolysis under harsh conditions or by enzymatic degradation...
2016: Marine Drugs
https://www.readbyqxmd.com/read/27266487/electrochemical-stability-window-of-imidazolium-based-ionic-liquids-as-electrolytes-for-lithium-batteries
#8
Saeed Kazemiabnavi, Zhengcheng Zhang, Katsuyo Thornton, Soumik Banerjee
This paper presents the computational assessment of the electrochemical stability of a series of alkyl methylimidazolium-based ionic liquids for their use as lithium battery electrolytes. The oxidation and reduction potentials of the constituent cation and anion of each ionic liquid with respect to a Li(+)/Li reference electrode were calculated using density functional theory following the method of thermodynamic cycles, and the electrochemical stability windows (ESW)s of these ionic liquids were obtained. The effect of varying the length of alkyl side chains of the methylimidazolium-based cations on the redox potentials and ESWs was investigated...
June 30, 2016: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/27260244/increased-effects-of-extracorporeal-shock-waves-combined-with-gentamicin-against-staphylococcus-aureus-biofilms-in%C3%A2-vitro%C3%A2-and-in%C3%A2-vivo
#9
Xin Qi, Yaochao Zhao, Jieyuan Zhang, Dan Han, Chunyuan Chen, Yinjun Huang, Xiaofeng Chen, Xianlong Zhang, Ting Wang, Xiaolin Li
An implant-associated bacterial infection is one of the most common and costly complications of orthopedic surgery. Once biofilms develop, it is extremely difficult to cure infections with antimicrobial agents. High-energy extracorporeal shock wave (ESW) treatment has been used for orthopedic-related diseases and has been found to be an effective bactericidal agent that is tolerable both in vitro and in vivo. The broad-spectrum antibiotic gentamicin exhibits bactericidal activity against Staphylococcus aureus, and bacterial resistance to gentamicin is lower...
September 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27240307/long-term-follow-up-of-cognitive-functions-in-patients-with-continuous-spike-waves-during-sleep-csws
#10
Lucia Maltoni, Annio Posar, Antonia Parmeggiani
Continuous spike-waves during sleep (CSWS) are associated with several cognitive, neurological, and psychiatric disorders, which sometimes persist after CSWS disappearance. The purpose of this retrospective study was to investigate the correlation between general (clinical and instrumental) and neuropsychological findings in CSWS, to identify variables that predispose patients to a poorer long-term neuropsychological outcome. Patients with spikes and waves during sleep with a frequency ≥25/min (spikes and waves frequency index - SWFI) were enrolled...
July 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27213514/laboratory-evaluation-of-electrostatic-spray-wet-scrubber-to-control-particulate-matter-emissions-from-poultry-facilities
#11
Ru Yu, Lingying Zhao, Lara Jane S Hadlocon, Heping Zhu, Sanjay K Ramdon
Particulate matter (PM) is a major air pollutant emitted from animal production and has significant impacts on health and the environment. Abatement of PM emissions is imperative and effective PM control technologies are strongly needed. In this work, an electrostatic spray wet scrubber (ESWS) technology designed for removal of PM (PM10 and PM2.5) emissions from poultry facilities was evaluated under simulated laboratory conditions. Effects of primary operating parameters including charging voltage (0 to 14 kV), air speed (0...
May 23, 2016: Environmental Technology
https://www.readbyqxmd.com/read/27160128/obesity-related-cardiovascular-behavior-in-children
#12
E A Özkan, H E Khosroshahi, M Kılıç, U A Geçit, E Domur
OBJECTIVE: Obesity is a chronic metabolic disorder and may associate with cardiovascular geometrical, structural and functional changes. The aim of this study is to assess the relationship between body mass index (BMI), body surface area (BSA) and arterial-ventricular elasticity (Ea and Ees respectively) and cardiovascular coupling and myocardial wall stress and fiber stress in obese children. PATIENTS AND METHODS: Sixty non-obese healthy children with BMI <85th percentile aged 6-17 years and 65 age and sex-matched children with BMI of ≥95th percentile, were included in the study...
April 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27126239/the-effect-of-radial-extracorporeal-shock-wave-stimulation-on-upper-limb-spasticity-in-chronic-stroke-patients-a-single-blind-randomized-placebo-controlled-study
#13
Robert Dymarek, Jakub Taradaj, Joanna Rosińczuk
The main purpose of this study was to determine the clinical, electrophysiological and thermal effects of radial extracorporeal shock wave (rESW) stimulation on upper limb muscles affected by spasticity in patients with chronic stroke. Patients included in the study were randomly assigned into the following two groups: 30 patients stimulated with active rESW (A); and 30 patients stimulated with placebo rESW (B). All patients were analyzed using the Modified Ashworth Scale (MAS) to test the spasticity levels of the elbow (E), radio carpal (RC) and fingers (FF) joints; surface electromyography (sEMG) was performed for the resting bioelectrical activity registration of the flexor carpi radialis (FCR) and flexor carpi ulnaris (FCU) muscles; and infrared thermal imaging (IRT) was used to assess the temperature distributions of the carpal flexor muscles (CFM)...
August 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27099130/medical-ozone-therapy-reduces-shock-wave-therapy-induced-renal-injury
#14
Sami Uğuz, Zafer Demirer, Bulent Uysal, Bilal Firat Alp, Ercan Malkoc, Ali Guragac, Turker Turker, Ferhat Ateş, Kenan Karademir, Ayhan Ozcan, Ibrahim Yildirim, Ahmet Korkmaz, Ahmet Guven
OBJECTIVES: Extracorporeal shock wave (ESW) lithotripsy is the preferred treatment modality for uncomplicated kidney stones. More recently free oxygen radical production following ESW application has been considered to be crucial in shock wave-induced renal damage. It has been shown that ozone therapy (OT) has ameliorative and preventive effects against various pathological conditions due to increased nitro-oxidative stress. In current study, we aimed to evaluate the efficacy of OT against ESW-induced renal injury...
July 2016: Renal Failure
https://www.readbyqxmd.com/read/27077981/effects-of-extracorporeal-shock-wave-on-upper-and-lower-limb-spasticity-in-post-stroke-patients-a-narrative-review
#15
Robert Dymarek, Kuba Ptaszkowski, Lucyna Słupska, Tomasz Halski, Jakub Taradaj, Joanna Rosińczuk
BACKGROUND: Effective treatment strategies for post-stroke muscle spasticity are still a significant interdisciplinary issue and challenge for neurologists, neurosurgeons, physiatrists nurses and physiotherapists. Extracorporeal shock wave (ESW) treatment is a well-supported physical modality used in a wide range of musculoskeletal disorders. The list of justified indications for ESW treatment and scientific areas of investigations is continuously evolving and adapting to different pathologies, including spasticity after stroke...
August 2016: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/27004982/ether-and-siloxane-functionalized-ionic-liquids-and-their-mixtures-as-electrolyte-for-lithium-ion-batteries
#16
Santosh N Chavan, Aarti Tiwari, Tharamani C Nagaiah, Debaprasad Mandal
The present study deals with an investigation of two novel imidazolium ionic liquids bearing ether-ether (1O2O2-Im-2O1) or ether-siloxane (1O2O2-Im-1SiOSi) functionalities with TFSI anion and their mixtures with propylene carbonate as electrolytes in lithium-ion batteries. The electrochemical stability and conductivity of these novel ILs were analyzed by electrochemical studies, such as cyclic voltammetry, linear sweep voltammetry and impedance measurements. The applicability of these ILs as electrolytes in Li-ion batteries was studied in the presence of a high concentration of LiTFSI (1 mol kg(-1) electrolyte) and the ether-ether IL was shown to possess a high electrochemical stability window (ESW) of 5...
June 28, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/26915841/early-steroid-withdrawal-in-recipients-of-a-kidney-transplant-from-a-living-donor-experience-of-a-single-mexican-center
#17
RANDOMIZED CONTROLLED TRIAL
J Andrade-Sierra, E Rojas-Campos, E Cardona-Muñoz, L A Evangelista-Carrillo, B Gómez-Navarro, E González-Espinoza, O Lugo-Lopez, J I Cerrillos-Gutiérrez, M Medina-Pérez, B Jalomo-Martínez, J J Nieves-Hernández, M Sandoval, J R Abundis-Jiménez, J N Ramírez-Robles, M A Villanueva-Pérez, F Monteón-Ramos, A M Cueto-Manzano
BACKGROUND: Early steroid withdrawal (ESW) can improve lipid and hemodynamic profiles without severe acute rejection (AR) events in renal transplant patients. Our objective was to evaluate the effects of ESW on the frequency and severity of AR. METHODS: A randomized, open-label, controlled clinical trial was performed on renal transplant recipients with a follow-up of 12 months. In the ESW group, patients were selected for corticosteroid treatment withdrawal on the fifth day post transplantation...
January 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/26906083/doxorubicin-loaded-nanobubbles-combined-with-extracorporeal-shock-waves-basis-for-a-new-drug-delivery-tool-in-anaplastic-thyroid-cancer
#18
Francesca Marano, Monica Argenziano, Roberto Frairia, Aloe Adamini, Ornella Bosco, Letizia Rinella, Nicoletta Fortunati, Roberta Cavalli, Maria Graziella Catalano
BACKGROUND: No standard chemotherapy is available for anaplastic thyroid cancer (ATC). Drug-loaded nanobubbles (NBs) are a promising innovative anticancer drug formulation, and combining them with an externally applied trigger may further control drug release at the target region. Extracorporeal shock waves (ESWs) are acoustic waves widely used in urology and orthopedics, with no side effects. The aim of the present work was to combine ESWs and new doxorubicin-loaded glycol chitosan NBs in order to target doxorubicin and enhance its antitumor effect in ATC cell lines...
May 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/26863924/focal-adhesion-kinase-signaling-mediated-the-enhancement-of-osteogenesis-of-human-mesenchymal-stem-cells-induced-by-extracorporeal-shockwave
#19
Jun Hu, Haojie Liao, Zebin Ma, Hongjiang Chen, Zhonglian Huang, Yuantao Zhang, Menglei Yu, Youbin Chen, Jiankun Xu
Extracorporeal shockwave (ESW) has been shown of great potential in promoting the osteogenesis of bone marrow mesenchymal stem cells (BMSCs), but it is unknown whether this osteogenic promotion effect can also be achieved in other MSCs (i.e., tendon-derived stem cells (TDSCs) and adipose-derived stem cells (ADSCs)). In the current study, we aimed not only to compare the osteogenic effects of BMSCs induced by ESW to those of TDSCs and ADSCs; but also to investigate the underlying mechanisms. We show here that ESW (0...
2016: Scientific Reports
https://www.readbyqxmd.com/read/26707301/human-leukocyte-antigen-mismatch-and-steroid-maintenance-in-kidney-transplantation
#20
B Chopra, K K Sureshkumar
BACKGROUND: This study aimed to analyze the impact of chronic steroid maintenance (CSM) vs early steroid withdrawal (ESW) in kidney transplant recipients (KTRs) stratified by the level of human leukocyte antigen (HLA) mismatch. METHODS: Adult KTRs between 2001 and 2011 who received antibody induction followed by calcineurin inhibitor (CNI)/mycophenolate mofetil (MMF) maintenance with or without steroid were identified from the Organ Procurement and Transplantation Network/United Network for Organ Sharing (OPTN/UNOS) database...
December 2015: Transplantation Proceedings
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