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Medical Treatment Ectopic Pregnancy

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https://www.readbyqxmd.com/read/28913127/severe-methotrexate-toxicity-after-treatment-for-ectopic-pregnancy-a-case-report
#1
Sunullah Soysal, Gökçe Anık İlhan, Mehmet Vural, Begüm Yıldızhan
Severe methotrexate toxicity due to medical treatment of an ectopic pregnancy is presented. The feasibility of low-dose use and success of methotrexate makes it the first drug in the medical treatment of ectopic pregnancies. Besides its advantages, it should be used with caution and severe toxicity should be kept in mind.
December 2016: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28888180/density-of-tubal-ring-vascularization-a-new-marker-for-prediction-of-success-of-medical-treatment-in-tubal-ectopic-pregnancy
#2
Serpil Aydoğmuş, Hüseyin Aydoğmuş, Servet Gençdal, Sefa Kelekçi
OBJECTIVES: The diagnosis of ectopic pregnancy has been facilitated especially by the use of Doppler ultrasonography. In previous studies the presence of peri-trophoblastic blood flow by Doppler ultrasound and the detection of a low-resistance, high-velocity flow pattern were defined as specific signs for trophoblastic tissue. The aim of this study was to evaluate the efficacy of Doppler ultrasonography in the prediction of treatment success in tubal pregnancies being treated with single dose conservative methotrexate...
August 26, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28865548/effects-of-adenomyosis-on-in%C3%A2-vitro-fertilization-treatment-outcomes-a-meta-analysis
#3
Grace Younes, Togas Tulandi
OBJECTIVE: To systematically review and summarize the existing evidence related to the effect of adenomyosis on fertility and on in vitro fertilization (IVF) clinical outcomes, and to explore the effects of surgical or medical treatments. DESIGN: Meta-analysis. SETTING: Not applicable. PATIENT(S): An electronic-based search was performed with the use of the following databases: Pubmed, Embase, Ovid Medline, Cochrane Central Register of Controlled Trials, and Google Scholar, identifying all related articles up to November 2016...
September 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28856829/efficacy-and-safety-of-very-early-medical-termination-of-pregnancy-a-cohort-study
#4
Isabella Bizjak, Christian Fiala, Linus Berggren, Helena Hognert, Ingrid Sääv, Johan Bring, Kristina Gemzell-Danielsson
OBJECTIVE: To assess the efficacy and safety of medical termination of pregnancy (MTOP) where no intrauterine pregnancy (IUP) is confirmed on ultrasound. DESIGN: Retrospective case note review. SETTING: Two gynecological clinics in Vienna, Austria and Gothenburg, Sweden. POPULATION: All women with gestations of ≤49 days undergoing an MTOP during 2004-2014 (Vienna) and 2012-2015 (Gothenburg). METHODS: Two study cohorts were created; women with and women without a confirmed IUP...
August 30, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28710772/outcomes-of-conception-subsequent-to-methotrexate-treatment-for-an-unruptured-ectopic-pregnancy
#5
Ran Svirsky, Ido Ben-Ami, Matitiahu Berkovitch, Reuvit Halperin, Uri Rozovski
OBJECTIVE: To assess the risk of adverse pregnancy outcomes in subsequent pregnancies among women treated with methotrexate for ectopic pregnancy. METHODS: In a retrospective single-center study, data were assessed for women treated with methotrexate for ectopic pregnancy at Asaf Harofe Medical Center, Zerifin, Israel, between May 2004 and May 2014. RESULTS: Overall, 226 women were treated with methotrexate for ectopic pregnancy and subsequently conceived...
July 15, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28704852/pregnancy-and-tumor-outcomes-in-women-with-prolactinoma
#6
Bárbara Araujo, Sandra Belo, Davide Carvalho
Context Management of prolactinomas during pregnancy has always been a challenge. There is a concern about the risk of tumor growth, as well as the effects of the treatment on the developing fetus. Another issue that has been less studied is the outcome of women with prolactinoma after pregnancy and lactation. Objectives To evaluate remission of hyperprolactinaemia after pregnancy and lactation in women with prolactinoma. To describe the safety of dopamine agonists for the fetus and pregnancy outcomes. Methods A retrospective study of 32 pregnancies in women with prolactinoma was conducted in a single-centre...
July 13, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28631522/evidence-based-management-of-non-tubal-ectopic-pregnancies
#7
Aderemi Olaoluwa Alalade, Fredrick John Ennis Smith, Charlotte Emma Kendall, Funlayo Odejinmi
Recent advances in ultrasonography and the use of other modalities including magnetic resonance imaging scans have led to the early and more accurate diagnosis of non-tubal ectopic pregnancies (NTE). As a result, the management of these pregnancies has evolved. This article addresses the management options currently available for NTE. While surgical management remains the mainstay of treatment for ovarian, abdominal and cornual ectopics, there is growing evidence that some of these can be managed medically...
November 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28626980/comparison-of-management-regimens-following-ultrasound-diagnosis-of-nontubal-ectopic-pregnancies-a-retrospective-cohort-study
#8
J Ramkrishna, G R Kan, K L Reidy, W C Ang, R Palma-Dias
OBJECTIVE: To review management options for nontubal ectopic pregnancies. DESIGN: Retrospective cohort study. SETTING: Tertiary hospital in Melbourne, Australia. POPULATION: A total of 100 nontubal pregnancies: 1 abdominal, 32 caesarean scar, 14 cervical, 41 cornual-interstitial, 12 ovarian. METHODS: Cases were classified according to ectopic site. Management categories were medical, surgical, combination or expectant...
June 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28609281/ectopic-ovarian-pregnancy-after-intracytoplasmic-sperm-injection-with-testicular-spermatozoa-a-case-report
#9
Javier García-Ferreyra, Roly Hilario, Julio Dueñas
Ovarian ectopic pregnancy is a rare event in both natural and assisted human reproduction settings. There are few reports of this event after in vitro fertilization. Diagnosis can be challenging, since it requires specific medical expertise. Patients with this condition call for careful management during treatment so as to not affect their fertility potential. This paper describes the case of a woman submitted to ICSI and embryo transfer who subsequently had an ovarian ectopic pregnancy and underwent a laparoscopic partial right oophorectomy...
June 1, 2017: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/28602476/comparison-of-ectopic-pregnancy-risk-among-transfers-of-embryos-vitrified-on-day-3-day-5-and-day-6
#10
COMPARATIVE STUDY
Tong Du, Hong Chen, Rong Fu, Qiuju Chen, Yun Wang, Ben W Mol, Yanping Kuang, Qifeng Lyu
OBJECTIVE: To compare ectopic pregnancy risk among transfers of embryos vitrified on day 3, day 5, and day 6. DESIGN: Retrospective cohort study. SETTING: Academic tertiary-care medical center. PATIENT(S): A total of 10,736 pregnancies after 23,730 frozen-thawed embryo transfer (FET) cycles of in vitro fertilization/intracytoplasmic sperm injection from March 2003 to May 2015. INTERVENTION(S): The ectopic pregnancy rate was compared among pregnancies resulting from transfers of embryos vitrified on day 3, day 5, and day 6...
July 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28552754/-interstitial-angular-and-cornual-pregnancies-diagnosis-treatment-and-subsequent-fertility
#11
M Nadi, C Richard, L Filipuzzi, L Bergogne, S Douvier, P Sagot
OBJECTIVE: Interstitial, angular and corneal pregnancies are not very frequent and often mistaken, each with its own definition and prognosis. The objective of this work is to relate 10 years experience of ectopic pregnancies at the UH in Dijon, based on the latest data from the literature in term of diagnosis, management and subsequent fertility. METHOD: This is a retrospective study carried out at the UH of Dijon from 01/01/2005 to 01/01/2015. From the medical records of each patient who presented a corneal, interstitial or angular pregnancy, we identified the risk factors for ectopic pregnancy (EG), the diagnostic and therapeutic means used, and the subsequent obstetrical events...
June 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/28523313/correlation-of-clinical-and-biological-evidence-a-dominant-therapeutic-element-of-succeeding-in-ectopic-pregnancy
#12
Simona Daniela NeamŢu, Damian DiŢescu, Maria ForŢofoiu, Liliana Stanca, Cristian Tigae, Mihaela Niculescu, Cristian Ovidiu NeamŢu, Maria Magdalena Manolea, Mirela Anişoara Siminel, Leontina Eugenia Şurtea, Adela Valeria NeamŢu, Marius Bogdan Novac, Liviu Vasile, Adrian Gluhovschi
Tubal pathology, smoking, pelvic inflammatory disease, miscarriage, medical or surgical abortion, usage of intrauterine devices (IUDs) for women with salpingitis latent injuries, older than 40 years, are risk factors for ectopic pregnancy. The objective of this study concerns the correlation of the clinical and biological evidence for the early diagnosis of the ectopic pregnancy and, as soon as possible, for the estimation for eventual risk of complications that may appear. The transvaginal ultrasound test, minimal increases in serum beta-human chorionic gonadotropin (β-hCG) dynamics and blood counts are investigations of choice in achieving our objective...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28523060/management-options-for-interstitial-ectopic-pregnancies-a-case-series
#13
Ilker Kahramanoglu, Zahid Mammadov, Hasan Turan, Aslihan Urer, Abdullah Tuten
OBJECTIVE: Ectopic pregnancy in the interstitial part of the Fallopian tubes can be life-threatining considering the thin myometrial tissue surrounding the gestational sac and highly vascularization which may result in catastrophic haemorrhage when interstitium is ruptured. The diagnosis and management is challenging. Conservative, medical, and surgical treatment options should be considered based on individual patient factors. METHODS: Four women were diagnosed with interstitial pregnancy in last five years in our tertiary center...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28288882/clinical-outcomes-of-patients-with-heterotopic-pregnancy-after-surgical-treatment
#14
Yiqi Guan, Caihong Ma
STUDY OBJECTIVE: This study aimed to review surgical management and clinical outcomes of patients with heterotopic pregnancy (HP) who underwent in vitro fertilization and embryo transfer (IVF-ET) and surgical treatment at the Assisted Reproductive Technology Center of Peking University Third Hospital from January 2010 to December 2015. DESIGN: We retrospectively analyzed 56 patients' general characteristics, diagnostic features, surgical management, and clinical outcomes according to medical records and follow-up telephone interviews...
March 10, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28288792/disparities-in-the-management-of-ectopic-pregnancy
#15
Jennifer Y Hsu, Ling Chen, Arielle R Gumer, Ana I Tergas, June Y Hou, William M Burke, Cande V Ananth, Dawn L Hershman, Jason D Wright
BACKGROUND: Ectopic pregnancy is common among young women. Treatment can consist of either surgery with salpingectomy or salpingostomy or medical management with methotrexate. In addition to acute complications, treatment of ectopic pregnancy can result in long-term sequelae that include decreased fertility. Little is known about the patterns of care and predictors of treatment in women with ectopic pregnancy. Similarly, data on outcomes for various treatments are limited. OBJECTIVE: We examined the patterns of care and outcomes for women with ectopic pregnancy...
July 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28285056/unilateral-salpingectomy-and-methotrexate-are-associated-with-a-similar-recurrence-rate-of-ectopic-pregnancy-in-patients-undergoing-in%C3%A2-vitro-fertilization
#16
Mohamad Irani, Alex Robles, Vinay Gunnala, Steven D Spandorfer
STUDY OBJECTIVE: To determine whether different treatment approaches of ectopic pregnancy (EP), particularly unilateral salpingectomy and methotrexate, affect its recurrence rate in patients undergoing in vitro fertilization (IVF). DESIGN: A retrospective cohort study (Canadian Task Force classification II-2). SETTING: An academic medical center. PATIENTS: Patients with a history of a previous EP who achieved pregnancy after IVF cycles between January 2004 and August 2015 were included...
March 8, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28217676/pretreatment-serum-human-chorionic-gonadotropin-cutoff-value-for-medical-treatment-success-with-single-dose-and-multi-dose-regimen-of-methotrexate-in-tubal-ectopic-pregnancy
#17
Junhwan Kim, Young Mi Jung, Da Yong Lee, Byung Chul Jee
OBJECTIVE: To investigate individual pretreatment serum human chorionic gonadotropin (hCG) cutoff value for medical treatment success with single-dose and multi-dose regimen of methotrexate in tubal ectopic pregnancy. METHODS: Eighty-five women who received methotrexate for the treatment of tubal ectopic pregnancy during 2003 to 2015 were selected. Fifty-three women received a single-dose regimen and 32 women received a multi-dose regimen. Medical treatment failure was defined as necessity of surgical treatment...
January 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28214759/the-role-of-hcg-increment-in-the-48h-prior-to-methotrexate-treatment-as-a-predictor-for-treatment-success
#18
Aviad Cohen, Benny Almog, Yoni Cohen, Guy Bibi, Eli Rimon, Ishai Levin
OBJECTIVE: To evaluate the role HCG change in the 48h prior to methotrexate treatment as a predictor for treatment success. STUDY DESIGN: Medical records of all women who were diagnosed with ectopic pregnancy between January 2001 and June 2013 were reviewed. Four hundred and nine patients received methotrexate due to ectopic pregnancy. The "single dose" methotrexate protocol with 50mg/m(2) was administered to patients with progressing ectopic pregnancy. HCG levels in days 1, 4 and 7 were used to evaluate methotrexate treatment success...
April 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28179198/cesarean-scar-ectopic-pregnancy-laparoscopic-resection-and-total-scar-dehiscence-repair-a-case-report
#19
Sara Mahgoub, Victor Gabriele, Emilie Faller, Bruno Langer, Arnaud Wattiez, Lise Lecointre, Cherif Akladios
STUDY OBJECTIVE: Illustrate laparoscopic technique for resection of cesarean scar ectopic pregnancy, associated with isthmocele repair. DESIGN: Case report SETTING: Tertiary referral centre in Strasbourg, France. The study was approved by the local IRB. BACKGROUND: Cesarean scar pregnancy is a rare form of ectopic pregnancy. The major risk of this type of pregnancy is the early uterine rupture with massive bleeding and maternal life-threatening...
February 4, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28127836/clinical-characteristics-of-persistent-ectopic-pregnancy-after-salpingostomy-and-influence-on-ongoing-pregnancy
#20
Yongli Zhang, Jinhong Chen, Wen Lu, Bilan Li, Guiqiang Du, Xiaoping Wan
AIM: The aim of this study was to assay the clinical characteristics of persistent ectopic pregnancy (PEP) and its influence on ongoing pregnancy. METHODS: We retrospectively reviewed 2498 patients who received salpingostomies as primary management for ectopic pregnancies from January 2004 to December 2009, using medical records and telephone inquiries. Clinical characteristics of the 52 patients (2.08%) who were diagnosed with PEP after salpingostomy were compared with those who received satisfactory treatment...
March 2017: Journal of Obstetrics and Gynaecology Research
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