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https://www.readbyqxmd.com/read/29352526/ectrims-ean-guideline-on-the-pharmacological-treatment-of-people-with-multiple-sclerosis
#1
X Montalban, R Gold, A J Thompson, S Otero-Romero, M P Amato, D Chandraratna, M Clanet, G Comi, T Derfuss, F Fazekas, H P Hartung, E Havrdova, B Hemmer, L Kappos, R Liblau, C Lubetzki, E Marcus, D H Miller, T Olsson, S Pilling, K Selmaj, A Siva, P S Sorensen, M P Sormani, C Thalheim, H Wiendl, F Zipp
BACKGROUND AND PURPOSE: Multiple sclerosis (MS) is a complex disease of the central nervous system. As new drugs are becoming available, knowledge on diagnosis and treatment must continuously evolve. There is therefore a need for a reference tool compiling current data on benefit and safety, to aid professionals in treatment decisions and use of resources across Europe. The European Committee of Treatment and Research in Multiple Sclerosis (ECTRIMS) and the European Academy of Neurology (EAN) have joined forces to meet this need...
January 19, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29351767/leading-for-the-long-haul-a-mixed-method-evaluation-of-the-sustainment-leadership-scale-sls
#2
Mark G Ehrhart, Elisa M Torres, Amy E Green, Elise M Trott, Cathleen E Willging, Joanna C Moullin, Gregory A Aarons
BACKGROUND: Despite our progress in understanding the organizational context for implementation and specifically the role of leadership in implementation, its role in sustainment has received little attention. This paper took a mixed-method approach to examine leadership during the sustainment phase of the Exploration, Preparation, Implementation, Sustainment (EPIS) framework. Utilizing the Implementation Leadership Scale as a foundation, we sought to develop a short, practical measure of sustainment leadership that can be used for both applied and research purposes...
January 19, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29351642/caregiver-provided-physical-therapy-home-programs-for-children-with-motor-delay-a-scoping-review
#3
Edward James R Gorgon
Background: Caregiver-provided physical therapy home programs (PTHP) play an important role in enhancing motor outcomes in pediatric patient populations. Purpose: This scoping review systematically mapped clinical trials of caregiver-provided PTHP that were aimed at enhancing motor outcomes in children who have or who are at risk for motor delay, with the purpose of (1) describing trial characteristics; (2) assessing methodologic quality, and (3) examining the reporting of caregiver-related components...
January 17, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29350411/goals-and-practicalities-of-immunoblotting-and-immunohistochemistry-a-guide-for-submission-to-the-british-journal-of-pharmacology
#4
EDITORIAL
Steve P H Alexander, Richard E Roberts, Brad R S Broughton, Christopher G Sobey, Christopher H George, S Clare Stanford, Giuseppe Cirino, James R Docherty, Mark A Giembycz, Daniel Hoyer, Paul A Insel, Angelo A Izzo, Yong Ji, David J MacEwan, Jonathan Mangum, Sue Wonnacott, Amrita Ahluwalia
No abstract text is available yet for this article.
February 2018: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29350194/detection-rate-of-fetal-distress-using-contraction-dependent-fetal-heart-rate-variability-analysis
#5
Guy J J Warmerdam, Rik Vullings, Judith O E H Van Laar, M Beatrijs Van der Hout-Van der Jagt, Jan W M Bergmans, Lars Schmitt, S Guid Oei
Monitoring of the fetal condition during labor is currently performed by cardiotocography (CTG). Despite the use of CTG in clinical practice, CTG interpretation suffers from a high inter- and intra-observer variability and a low specificity. In addition to CTG, analysis of fetal heart rate variability (HRV) has been shown to provide information on fetal distress. However, fetal HRV can be strongly influenced by uterine contractions, particularly during the second stage of labor. Therefore, the aim of this study is to examine if distinguishing contractions from rest periods can improve the detection rate of HRV features for fetal distress during the second stage of labor...
January 19, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29349931/biomimetic-architectures-for-peripheral-nerve-repair-a-review-of-biofabrication-strategies
#6
REVIEW
Paul A Wieringa, Ana Rita Gonçalves de Pinho, Silvestro Micera, Richard J A van Wezel, Lorenzo Moroni
Biofabrication techniques have endeavored to improve the regeneration of the peripheral nervous system (PNS), but nothing has surpassed the performance of current clinical practices. However, these current approaches have intrinsic limitations that compromise patient care. The "gold standard" autograft provides the best outcomes but requires suitable donor material, while implantable hollow nerve guide conduits (NGCs) can only repair small nerve defects. This review places emphasis on approaches that create structural cues within a hollow NGC lumen in order to match or exceed the regenerative performance of the autograft...
January 19, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29349924/parental-supervision-for-their-children-s-toothbrushing-mediating-effects-of-planning-self-efficacy-and-action-control
#7
Kyra Hamilton, Stephen Cornish, Aaron Kirkpatrick, Jeroen Kroon, Ralf Schwarzer
OBJECTIVES: With 60-90% of children worldwide reportedly experiencing dental caries, poor oral health in the younger years is a major public health issue. As parents are important to children's oral hygiene practices, we examined the key self-regulatory behaviours of parents for supervising their children's toothbrushing using the health action process approach. DESIGN AND METHOD: Participants (N = 281, 197 mothers) comprised Australian parents of 2- to 5-year-olds...
January 18, 2018: British Journal of Health Psychology
https://www.readbyqxmd.com/read/29349733/point-of-care-ultrasound-pocus-of-the-upper-airway
#8
REVIEW
Kong Eric You-Ten, Naveed Siddiqui, Wendy H Teoh, Michael S Kristensen
Airway management is a critical skill in the practice of several medical specialities including anesthesia, emergency medicine, and critical care. Over the years mounting evidence has showed an increasing role of ultrasound (US) in airway management. The objective of this narrative review is to provide an overview of the indications for point-of-care ultrasound (POCUS) of the upper airway. The use of US to guide and assist clinical airway management has potential benefits for both provider and patient. Ultrasound can be utilized to determine airway size and predict the appropriate diameter of single-lumen endotracheal tubes (ETTs), double-lumen ETTs, and tracheostomy tubes...
January 18, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29349482/-esophageal-diverticula-excluding-cricopharyngeal-diverticula
#9
C A Gutschow, H Schmidt
Diverticula of the middle and lower third of the esophagus are commonly associated with esophageal motility disorders. The increase of intraluminal pressure leads to an outpouching of the mucosal and submucosal layers through the esophageal muscle coat. These pouches are also called false diverticula, because they only consist of the mucosal and submucosal esophageal layers. In contrast, the more rarely encountered true diverticula that retain the complete esophageal wall are generally associated with periesophageal granulomatous lymph node disease...
January 18, 2018: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29348874/value-of-ct-mri-fusion-in-iodine-125-brachytherapy-for-high-grade-glioma
#10
Yang Gao, Yan Han, Guo Nan, Man Hu, Xiaobin Zhou, Xiaokun Hu
Purposes: To develop a fast, accurate and robust method of fusing Computed Tomography (CT) with pre-operative Magnetic Resonance Imaging (MRI) and evaluate the impact of using the fused data on the implantation of Iodine-125 (125I) seeds for brachytherapy of high-grade gliomas (HGG). Methods: A study was performed on a cohort of 10 consecutive patients with HGG were treated by 125I brachytherapy with CT-MRI fusion image guided (CMGB), and 10 patients treated with CT alone guided (CGB)...
December 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29348709/perioperative-medicine-a-burgeoning-field-with-profound-importance-to-a-modern-clinician
#11
EDITORIAL
Vinaya Gaduputi, Sridhar Chilimuri, Kinesh Changela
AIMS AND SCOPE This article serves in introducing the readers to the developing field of perioperative medicine. We have made an effort to come up with the latest management guidelines covering multiple subspecialties in form of a special supplement. This compendium in perioperative medicine serves as a comprehensive guide to a practicing clinician, in managing patients with various medical comorbidities undergoing surgical procedures and avoiding common pitfalls.
2018: Health Services Insights
https://www.readbyqxmd.com/read/29348320/-18f-fdg-pet-ct-in-local-ablative-therapies-a-systematic-review
#12
Erik H J G Aarntzen, Linda Heijmen, Wim J G Oyen
Driven by the continuous improvement of the accuracy of cross-sectional imaging, image-guided minimally invasive local ablative therapies have received incremental interest over the past years. This study systematically reviews the currently available literature on [18F]FDG PET/CT to monitor the efficacy of these local ablative therapies. By including all local ablative treatment modalities, tumor types and organ sites, we provide a comprehensive overview of current status, identify general patterns across studies and provide recommendations for future studies and clinical practice...
January 18, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29348052/thirty-day-complication-rate-of-percutaneous-gastrojejunostomy-and-gastrostomy-tube-insertion-using-a-single-puncture-dual-anchor-technique
#13
Rebecca Zener, Alexandra C Istl, Kerollos N Wanis, David Hocking, Jacob Kachura, Shaker Alshehri, Amol Mujoomdar, Steven Latosinsky, Daniele Wiseman
PURPOSE: Our objective was to assess 30-day mortality and complication rates associated with percutaneous enteral feeding tube insertion using a single-puncture, dual-suture anchor gastropexy and peel-away sheath technique. We explored differences in complications based on indication and gastrostomy versus gastrojejunostomy tube. METHODS: A retrospective review was conducted of adult patients undergoing fluoroscopically guided gastrojejunostomy (GJ) and gastrostomy (G) tube insertions between July 2011 and 2014 by five interventional radiologists at a single tertiary care centre...
January 10, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29346744/2017-national-standards-for-diabetes-self-management-education-and-support
#14
Joni Beck, Deborah A Greenwood, Lori Blanton, Sandra T Bollinger, Marcene K Butcher, Jo Ellen Condon, Marjorie Cypress, Priscilla Faulkner, Amy Hess Fischl, Theresa Francis, Leslie E Kolb, Jodi M Lavin-Tompkins, Janice MacLeod, Melinda Maryniuk, Carolé Mensing, Eric A Orzeck, David D Pope, Jodi L Pulizzi, Ardis A Reed, Andrew S Rhinehart, Linda Siminerio, Jing Wang
Purpose The purpose of this study is to review the literature for Diabetes Self-Management Education and Support (DSMES) to ensure the National Standards for DSMES (Standards) align with current evidence-based practices and utilization trends. Methods The 10 Standards were divided among 20 interdisciplinary workgroup members. Members searched the current research for diabetes education and support, behavioral health, clinical, health care environment, technical, reimbursement, and business practice for the strongest evidence that guided the Standards revision...
February 2018: Diabetes Educator
https://www.readbyqxmd.com/read/29346409/prediction-of-absolute-risk-of-acute-graft-versus-host-disease-following-hematopoietic-cell-transplantation
#15
Catherine Lee, Sebastien Haneuse, Hai-Lin Wang, Sherri Rose, Stephen R Spellman, Michael Verneris, Katharine C Hsu, Katharina Fleischhauer, Stephanie J Lee, Reza Abdi
Allogeneic hematopoietic cell transplantation (HCT) is the treatment of choice for a variety of hematologic malignancies and disorders. Unfortunately, acute graft-versus-host disease (GVHD) is a frequent complication of HCT. While substantial research has identified clinical, genetic and proteomic risk factors for acute GVHD, few studies have sought to develop risk prediction tools that quantify absolute risk. Such tools would be useful for: optimizing donor selection; guiding GVHD prophylaxis, post-transplant treatment and monitoring strategies; and, recruitment of patients into clinical trials...
2018: PloS One
https://www.readbyqxmd.com/read/29346354/compassion-from-a-palliative-care-perspective
#16
Antonio Fernando, Conor Rea, Phillipa J Malpas
BACKGROUND: Compassion is a core virtue in medicine and lies at the heart of good medical care. It connects us to each other and reflects our need for relationships with others. AIM: Our aim is to explore how palliative care patients perceive, understand and experience compassion from health professionals, and to inform clinical practice. METHODS: Seven hospice managers in the North Island of New Zealand were contacted and invited to join the study...
January 19, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29345866/cognitive-impairment-in-patients-with-depression-awareness-assessment-and-management
#17
REVIEW
Larry Culpepper, Raymond W Lam, Roger S McIntyre
​​ Cognitive impairment is a common, often persistent, symptom of major depressive disorder (MDD) that is disproportionately represented in patients who have not returned to full psychosocial functioning. The ultimate goal of treatment in depression is full functional recovery, and assessing patients for cognitive impairment and selecting treatments that address cognitive dysfunction should lead to improved functional outcomes. Unfortunately, many clinicians use screening and assessment tools that are not suited for measuring cognitive impairment in patients with depression...
November 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29345481/the-influence-of-low-barrier-and-voluntary-service-policies-on-survivor-empowerment-in-a-domestic-violence-housing-organization
#18
Nkiru Nnawulezi, Surbhi Godsay, Cris M Sullivan, Suzanne Marcus, Margaret Hacskaylo
The purpose of community-based domestic violence crisis housing programs (e.g., shelters) is to provide a safe setting that promotes empowerment for survivors of intimate partner violence. For staff to reach this aim, the program must have formal structures and processes in place to support such efforts. This study explored how low-barrier and voluntary service policies influenced staff practices and survivor empowerment. Low-barrier policies require that programs remove barriers that prevent survivors, particularly those who have mental health concerns and/or addictions, from being able to access services...
January 18, 2018: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/29345003/investigation-of-attributes-which-guide-choice-in-cataract-surgery-services-in-urban-sydney-australia
#19
Celeste Gilbert, Lisa Keay, Anna Palagyi, Vu Quang Do, Peter McCluskey, Andrew White, Nicole Carnt, Fiona Stapleton, Tracey-Lea Laba
BACKGROUND: It is critical to consult patients to develop patient-centred cataract surgery care. We aimed to identify attributes patients consider when making decisions about cataract surgery in an Australian context, where both publicly and privately funded surgery are available. This is the first step in investigating how decisions are made about cataract surgery services. METHODS: This observational qualitative study was undertaken in two public hospitals and one private practice in Sydney, Australia...
January 17, 2018: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29344589/magnetism-tuning-strategies-for-graphene-oxide-based-on-magnetic-oligoacene-oxide-patches-model
#20
Yanjie Wen, Chia-Liang Yen, Linyin Yan, Hirohiko Kono, Sheng-Hsien Lin, Yong-Chien Ling
Graphene oxide (GO) has wide application potential owing to its 2D structure and diverse modification sites for various targeted uses. The introduction of magnetism into GO structures has further advanced the controllability of the application of GO materials. Herein, the concept of modular design and modeling was applied to tune the magnetism of GO. To obtain desirable magnetic properties, diradical-structured GO patches were formed by the introduction of two functional groups to break the Kekule structure of the benzene ring...
January 18, 2018: Physical Chemistry Chemical Physics: PCCP
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