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https://www.readbyqxmd.com/read/29240816/the-sociotype-construct-gauging-the-structure-and-dynamics-of-human-sociality
#1
Pedro C Marijuán, Jesús Montero-Marín, Jorge Navarro, Javier García-Campayo, Raquel Del Moral
Exploring the pertinence of a "sociotype" construct, established along the conceptual chain genotype-phenotype-sociotype, is the essential purpose of the present paper. Further, by following the sociotype's conceptual guidelines, a new psychometric indicator has been developed in order to gauge the level of social interaction around each individual-the sociotype questionnaire (SOCQ). A first version of this questionnaire has been elaborated by gathering data about the different classes of social bonds (family, friends, acquaintances, and work/study colleagues) in general population and about the dynamic update of these bonds via face-to-face conversation and other modes of interaction...
2017: PloS One
https://www.readbyqxmd.com/read/29239812/dosimetric-impact-of-inter-observer-catheter-reconstruction-variability-in-ultrasound-based-high-dose-rate-prostate-brachytherapy
#2
Alexandru Nicolae, Jure Murgic, Ivan Kruljac, Lior Dubnitzky, Laura D'Alimonte, Lin Lu, Aaron Cumal, Niki Law, Gerard Morton, Andrew Loblaw, Hans T Chung, Ananth Ravi
PURPOSE: To investigate the dosimetric impact of interobserver catheter reconstruction variability in transrectal ultrasound-guided prostate high-dose-rate (HDR) brachytherapy. METHODS AND MATERIALS: Twenty consecutive patients with intermediate- or high-risk prostate cancer were treated with a single, 15-Gy HDR brachytherapy boost as part of this study. The treated plan was used as the study reference plan (PR). Three expert treatment planners (observers) manually reconstructed the catheter paths on the static three-dimensional transrectal ultrasound images, and new plans were generated from the updated positions (POBS); subsequently, the dwell time and positions from the POBS plans were superimposed on the PR catheter paths to evaluate the dosimetric effect of the interobserver variations (PEVAL)...
November 24, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29237630/diagnosis-and-treatment-of-pruritus
#3
REVIEW
Dominik Nowak, Jensen Yeung
OBJECTIVE: To describe an approach that allows for a streamlined assessment and accurate differentiation of most patients with itch in primary care and to provide an update on the available nonpharmacologic, topical, and systemic therapies. SOURCES OF INFORMATION: MEDLINE (Ovid) and PubMed were searched for the key words itch or pruritus. Searches were refined for each cause and treatment by adding appropriate key words, and subsequent hand searches of the references of retrieved literature were performed...
December 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29233085/an-oncology-clinical-trial-design-with-randomization-adaptive-to-both-short-and-long-term-responses
#4
Hao Liu, Xiao Lin, Xuelin Huang
In oncology clinical trials, both short-term response and long-term survival are important. We propose an urn-based adaptive randomization design to incorporate both of these two outcomes. While short-term response can update the randomization probability quickly to benefit the trial participants, long-term survival outcome can also change the randomization to favor the treatment arm with definitive therapeutic benefit. Using generalized Friedman's urn, we derive an explicit formula for the limiting distribution of the number of subjects assigned to each arm...
January 1, 2017: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/29232249/clinical-trials-in-valvular-surgery-a-2018-update
#5
Bobby Yanagawa, Amine Mazine, Derrick Y Tam, Subodh Verma
PURPOSE OF REVIEW: There is a growing emphasis on the conduct of large-scale, multicenter randomized controlled trials (RCTs) to guide decision-making in cardiac surgery. Here we review recent landmark RCTs in cardiac valvular surgery. RECENT FINDINGS: RCTs are the gold-standard level of data in medicine. However, there are unique challenges of conducting large-scale surgical trials including funding, blinding, generalizability, nonstandardization of the surgical technique, crossover, among others...
December 11, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29230798/botulinum-toxin-type-a-therapy-for-cervical-dystonia
#6
REVIEW
Mafalda Castelão, Raquel E Marques, Gonçalo S Duarte, Filipe B Rodrigues, Joaquim Ferreira, Cristina Sampaio, Austen P Moore, João Costa
BACKGROUND: This is an update of a Cochrane Review first published in 2005. Cervical dystonia is the most common form of focal dystonia and is a highly disabling movement disorder characterised by involuntary, usually painful, head posturing. Currently, botulinum toxin type A (BtA) is considered the first line therapy for this condition. OBJECTIVES: To compare the efficacy, safety, and tolerability of botulinum toxin type A (BtA) versus placebo in people with cervical dystonia...
December 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29226150/transversus-abdominis-plane-block-an-updated-review-of-anatomy-and-techniques
#7
REVIEW
Hsiao-Chien Tsai, Takayuki Yoshida, Tai-Yuan Chuang, Sheng-Feng Yang, Chuen-Chau Chang, Han-Yun Yao, Yu-Ting Tai, Jui-An Lin, Kung-Yen Chen
Purpose of Review: Transversus abdominis plane (TAP) block is a regional technique for analgesia of the anterolateral abdominal wall. This review highlights the nomenclature system and recent advances in TAP block techniques and proposes directions for future research. Recent Findings: Ultrasound guidance is now considered the gold standard in TAP blocks. It is easy to acquire ultrasound images; it can be used in many surgeries involving the anterolateral abdominal wall...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29219094/a-collaborative-approach-to-adopting-adapting-guidelines-the-australian-24-hour-movement-guidelines-for-the-early-years-birth-to-5-years-an-integration-of-physical-activity-sedentary-behavior-and-sleep
#8
Anthony D Okely, Davina Ghersi, Kylie D Hesketh, Rute Santos, Sarah P Loughran, Dylan P Cliff, Trevor Shilton, David Grant, Rachel A Jones, Rebecca M Stanley, Julie Sherring, Trina Hinkley, Stewart G Trost, Clare McHugh, Simon Eckermann, Karen Thorpe, Karen Waters, Timothy S Olds, Tracy Mackey, Rhonda Livingstone, Hayley Christian, Harriette Carr, Adam Verrender, João R Pereira, Zhiguang Zhang, Katherine L Downing, Mark S Tremblay
BACKGROUND: In 2017, the Australian Government funded the update of the National Physical Activity Recommendations for Children 0-5 years, with the intention that they be an integration of movement behaviours across the 24-h period. The benefit for Australia was that it could leverage research in Canada in the development of their 24-h guidelines for the early years. Concurrently, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group published a model to produce guidelines based on adoption, adaption and/or de novo development using the GRADE evidence-to-decision framework...
November 20, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29218460/a-novel-adaptive-deformable-model-for-automated-optic-disc-and-cup-segmentation-to-aid-glaucoma-diagnosis
#9
Muhammad Salman Haleem, Liangxiu Han, Jano van Hemert, Baihua Li, Alan Fleming, Louis R Pasquale, Brian J Song
This paper proposes a novel Adaptive Region-based Edge Smoothing Model (ARESM) for automatic boundary detection of optic disc and cup to aid automatic glaucoma diagnosis. The novelty of our approach consists of two aspects: 1) automatic detection of initial optimum object boundary based on a Region Classification Model (RCM) in a pixel-level multidimensional feature space; 2) an Adaptive Edge Smoothing Update model (AESU) of contour points (e.g. misclassified or irregular points) based on iterative force field calculations with contours obtained from the RCM by minimising energy function (an approach that does not require predefined geometric templates to guide auto-segmentation)...
December 7, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/29216935/-chest-compression-on-cpr-and-active-abdominal-on-cpr
#10
Lixiang Wang, Wei Song, Sisen Zhang
Chest compression cannot be effectively applied under certain situations, such as chest wall deformity, rib fracture, or hemopneumothorax. Active abdominal compression-decompression cardiopulmonary resuscitation (AACD-CPR) could reach better resuscitation outcomes in certain cardiac arrest (CA) patients. AACD-CPR can strengthen the high quality of cardiopulmonary resuscitation (CPR) in "2015 American Heart Association for cardiopulmonary resuscitation and emergency cardiovascular care update guide". The two methods can complement each other in opposite direction, and implement the "2016 national consensus on cardiopulmonary resuscitation on CPR in China", which is an important part of the wisdom to the Chinese CPR...
December 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/29215315/internet-based-vs-face-to-face-cognitive-behavior-therapy-for-psychiatric-and-somatic-disorders-an-updated-systematic-review-and-meta-analysis
#11
Per Carlbring, Gerhard Andersson, Pim Cuijpers, Heleen Riper, Erik Hedman-Lagerlöf
During the last two decades, Internet-delivered cognitive behavior therapy (ICBT) has been tested in hundreds of randomized controlled trials, often with promising results. However, the control groups were often waitlisted, care-as-usual or attention control. Hence, little is known about the relative efficacy of ICBT as compared to face-to-face cognitive behavior therapy (CBT). In the present systematic review and meta-analysis, which included 1418 participants, guided ICBT for psychiatric and somatic conditions were directly compared to face-to-face CBT within the same trial...
December 7, 2017: Cognitive Behaviour Therapy
https://www.readbyqxmd.com/read/29208728/imaging-in-low-grade-glioma-a-guide-for-neurologists
#12
REVIEW
Jennifer Larsen, Nigel Hoggard, Fiona M McKevitt
The management of low-grade glioma (LGG) is shifting as evidence has emergedthat refutes the previously commonplace imaging-based 'watch and wait' approach, in favour of early aggressive surgical resection. This coupled with the recent 2016 update to the World Health Organisation Classification of Tumours of the Central Nervous System is changing LGG imaging and management. Recently in Practical Neurology the contemporary management of low-grade glioma and the changes to this grading system were discussed in detail...
December 5, 2017: Practical Neurology
https://www.readbyqxmd.com/read/29203985/setting-up-of-the-indian-hipec-registry-a-registry-for-indian-patients-with-peritoneal-surface-malignancies
#13
Aditi Bhatt, Sanket Mehta, Ramakrishnan As, Pankaj Pande, Firoz Rajan, Ashvin Rangole, Avanish Saklani, Kayomarz Sethna, Shivendra Singh, Shabber Zaveri, K S Gopinath
There are various registries for patients with peritoneal metastases (PM) that aid pooling of data and generate evidence that dictates current clinical practice. This manuscript describes the setting up of the Indian HIPEC registry that was set up with a similar goal by a group of Indian surgeons. This is a registry for patients with PM treated with CRS and HIPEC in India. It also acts as a database for storing treatment-related information. Patients with PM from colorectal ovarian, gastric, appendiceal tumors, and other rare peritoneal tumors/metastases from rare tumors are enrolled in the registry...
December 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29203269/clinically-localized-prostate-cancer-aua-astro-suo-guideline-part-i
#14
Martin G Sanda, Jeffrey A Cadeddu, Erin Kirkby, Ronald C Chen, Tony Crispino, Joann Fontanarosa, Stephen J Freedland, Kirsten Greene, Laurence H Klotz, Danil V Makarov, Joel B Nelson, George Rodrigues, Howard M Sandler, Mary Ellen Taplin, Jonathan R Treadwell
PURPOSE: This guideline is structured to provide a clinical framework stratified by cancer severity to facilitate care decisions and guide the specifics of implementing the selected management options. The summary presented herein represents Part I of the two-part series dedicated to Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline discussing risk stratification and care options by cancer severity. Please refer to Part II for discussion of specific care options and outcome expectations and management...
December 1, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29193737/laboratory-testing-in-patients-treated-with-direct-oral-anticoagulants-a-practical-guide-for-clinicians
#15
REVIEW
Jonathan Douxfils, Walter Ageno, Charles-Marc Samama, Sarah Lessire, Hugo Ten Cate, Peter Verhamme, Jean-Michel Dogné, François Mullier
One of the key benefits of the direct oral anticoagulants (DOACs) is that they do not require routine laboratory monitoring. Nevertheless, assessment of DOAC exposure and anticoagulant effects may become useful in various clinical scenarios. The four approved DOACs - apixaban, dabigatran etexilate, edoxaban and rivaroxaban - have different characteristics impacting assay selection and the interpretation of results. This article provides an updated overview on 1) which test to use (and their advantages and limitations), 2) when to assay DOAC levels, 3) how to interpret the results relating to bleeding risk, emergency situations and perioperative management, and 4) what is the impact of DOACs on routine and specialised coagulation assays...
November 29, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29193527/telemedicine-follow-up-facilitates-more-comprehensive-diabetes-foot-ulcer-care-a-qualitative-study-in-home-based-and-specialist-health-care
#16
Beate-Christin Hope Kolltveit, Sally Thorne, Marit Graue, Eva Gjengedal, Marjolein M Iversen, Marit Kirkevold
AIMS AND OBJECTIVES: To investigate the application of a telemedicine intervention in diabetes foot ulcer care, and its implications for the health care professionals in the clinical field. BACKGROUND: Contextual factors are found to be important when applying technology in health care and applying telemedicine in home-based care has been identified as particularly complex. DESIGN AND METHODS: We conducted field observations and individual interviews among health care professionals in home-based care and specialist health care in a diabetes foot care telemedicine RCT (Clin...
November 29, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29189505/development-of-a-comprehensive-and-interactive-tool-to-inform-state-violence-and-injury-prevention-plans
#17
Lauren Wilson, Angela J Deokar, Araya Zaesim, Karen Thomas, Marcie-Jo Kresnow-Sedacca
CONTEXT: The Center of Disease Control and Prevention's Core State Violence and Injury Prevention Program (Core SVIPP) provides an opportunity for states to engage with their partners to implement, evaluate, and disseminate strategies that lead to the reduction and prevention of injury and violence. Core SVIPP requires awardees to develop or update their state injury and violence plans. Currently, literature informing state planning efforts is limited, especially regarding materials related to injury and violence...
January 2018: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/29187629/testing-differential-use-of-payoff-biased-social-learning-strategies-in-children-and-chimpanzees
#18
REVIEW
Gillian L Vale, Emma G Flynn, Jeremy Kendal, Bruce Rawlings, Lydia M Hopper, Steven J Schapiro, Susan P Lambeth, Rachel L Kendal
Various non-human animal species have been shown to exhibit behavioural traditions. Importantly, this research has been guided by what we know of human culture, and the question of whether animal cultures may be homologous or analogous to our own culture. In this paper, we assess whether models of human cultural transmission are relevant to understanding biological fundamentals by investigating whether accounts of human payoff-biased social learning are relevant to chimpanzees (Pan troglodytes). We submitted 4- and 5-year-old children (N = 90) and captive chimpanzees (N = 69) to a token-reward exchange task...
December 13, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29186587/effective-online-bayesian-phylogenetics-via-sequential-monte-carlo-with-guided-proposals
#19
Mathieu Fourment, Brian C Claywell, Vu Dinh, Connor McCoy, Frederick A Matsen Iv, Aaron E Darling
Modern infectious disease outbreak surveillance produces continuous streams of sequence data which require phylogenetic analysis as data arrives. Current software packages for Bayesian phylogenetic inference are unable to quickly incorporate new sequences as they become available, making them less useful for dynamically unfolding evolutionary stories. This limitation can be addressed by applying a class of Bayesian statistical inference algorithms called sequential Monte Carlo (SMC) to conduct online inference, wherein new data can be continuously incorporated to update the estimate of the posterior probability distribution...
November 27, 2017: Systematic Biology
https://www.readbyqxmd.com/read/29184385/aflibercept-treatment-for-neovascular-amd-beyond-the-first-year-consensus-recommendations-by-a-uk-expert-roundtable-panel-2017-update
#20
EDITORIAL
Praveen J Patel, Helen Devonport, Sobha Sivaprasad, Adam H Ross, Gavin Walters, Richard P Gale, Andrew J Lotery, Sajjad Mahmood, James S Talks, Jackie Napier
National recommendations on continued administration of aflibercept solution for injection after the first year of treatment for neovascular age-related macular degeneration (nAMD) have been developed by an expert panel of UK retina specialists, based on clinician experience and treatment outcomes seen in year 2. The 2017 update reiterates that the treatment goal is to maintain or improve the macular structural and functional gains achieved in year 1 while attempting to reduce or minimize the treatment burden, recognizing the need for ongoing treatment...
2017: Clinical Ophthalmology
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