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https://www.readbyqxmd.com/read/28319151/ethical-problems-in-an-era-where-disasters-have-become-a-part-of-daily-life-a-qualitative-study-of-healthcare-workers-in-turkey
#1
M Murat Civaner, Kevser Vatansever, Kayihan Pala
BACKGROUND: Natural disasters, armed conflict, migration, and epidemics today occur more frequently, causing more death, displacement of people and economic loss. Their burden on health systems and healthcare workers (HCWs) is getting heavier accordingly. The ethical problems that arise in disaster settings may be different than the ones in daily practice, and can cause preventable harm or the violation of basic human rights. Understanding the types and the determinants of ethical challenges is crucial in order to find the most benevolent action while respecting the dignity of those affected people...
2017: PloS One
https://www.readbyqxmd.com/read/28318010/ataxia-telangiectasia-recommendations-for-multidisciplinary-treatment
#2
REVIEW
Nienke J H van Os, Charlotte A Haaxma, Michiel van der Flier, Peter J F M Merkus, Marcel van Deuren, Imelda J M de Groot, Jan Loeffen, Bart P C van de Warrenburg, Michèl A A P Willemsen
Ataxia-telangiectasia is a rare, neurodegenerative, and multisystem disease, characterized by cerebellar ataxia, oculocutaneous telangiectasia, immunodeficiency, progressive respiratory failure, and an increased risk of malignancies. It demands specialized care tailored to the individual patient's needs. Besides the classic ataxia-telangiectasia phenotype, a variant phenotype exists with partly overlapping but some distinctive disease characteristics. This guideline summarizes frequently encountered medical problems in the disease course of patients with classic and variant ataxia-telangiectasia, in the domains of neurology, immunology and infectious diseases, pulmonology, anaesthetic and perioperative risk, oncology, endocrinology, and nutrition...
March 20, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28316074/a-comparison-of-alk-gene-rearrangement-and-alk-protein-expression-in-primary-lung-carcinoma-and-matched-metastasis
#3
Humberto E Trejo Bittar, Alyssa Luvison, Caitlyn Miller, Sanja Dacic
AIMS: The 2013 CAP/IASLC/AMP guideline for EGFR and ALK testing in lung carcinoma indicates that either the primary tumor or the metastasis is suitable for testing. The heterogeneity of gene mutations has been extensively studied, while similar reports on gene rearrangements are limited. The aim of this study was to determine if ALK status between primary tumor and matched metastasis differs. METHODS AND RESULTS: 15 ALK-FISH rearranged and 19 non-ALK-FISH rearranged adenocarcinomas were retrospectively collected based on availability of tissue from a matched metastatic site...
March 17, 2017: Histopathology
https://www.readbyqxmd.com/read/28315896/responsive-feeding-strategies-to-promote-healthy-mealtime-interactions
#4
Maureen M Black, Kristen M Hurley
Responsive feeding is a derivative of responsive parenting that has been applied to infant and young child feeding. With a theoretical basis in the reciprocal interactions between parents and children, responsive feeding is particularly relevant during complementary feeding as young children progress from an exclusively milk-based liquid diet to the family diet and self-feeding. The period of complementary feeding includes multiple developmental changes that may threaten a successful transition and lead to growth and feeding problems...
2017: Nestlé Nutrition Institute Workshop Series
https://www.readbyqxmd.com/read/28315625/endometrial-injury-for-women-with-previous-in-vitro-fertilization-failure-does-it-improve-pregnancy-rate
#5
(no author information available yet)
Implantation failure is one of the major factors limiting success of in vitro fertilization (IVF) treatment. According to ESHRE 2009 data only 32% of fresh embryo transfers resulted in clinical pregnancies. There are many ideas to improve the treatment outcomes, endometrial injury being one of them. It has been suggested that local endometrial injury, performed either by pipelle biopsy or hysteroscopy, may increase clinical pregnancy rate. However, up to date literature is widely disparate on that subject. There is no conclusion with regard to optimal timing, the number and technique of the procedure...
November 19, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28315567/a-practical-guide-for-building-a-highway-between-atria-during-transseptal-puncture-without-radiation
#6
Yuan Yuan, Deyong Long, Caihua Sang, Ling Tao, Jianzeng Dong, Changsheng Ma
OBJECTIVE: To investigate whether switching the ablation catheter between the right and left atria through transseptal puncture site can be accurately performed without fluoroscopy. METHODS: Forty patients with persistent atrial fibrillation (mean age, 60.2±7.4 years; 65% males) got "2C3L" approach were randomized in a 1:1 ratio to undergo either crossing interatrial septum guided by fluoroscopy (trackless group) or crossing septum guided by track image that was mapped by Carto3 system (track group)...
March 9, 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28315527/standards-of-practice-applying-genetics-and-genomics-resources-to-oncology%C3%A2
#7
Alice S Kerber, Nancy J Ledbetter
Knowledge about genetics and genomics and its application to oncology care is rapidly expanding and evolving. As a result, oncology nurses at all levels must develop and maintain their knowledge of genetics and genomics, as well as be aware of resources to guide practice. This article focuses on implementation of the standards described in the updated Genetics/Genomics Nursing: Scope and Standards of Practice by the basic practitioner.
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April 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28315192/discrete-choice-experiment-attribute-selection-using-a-multinational-interview-study-treatment-features-important-to-patients-with-type-2-diabetes-mellitus
#8
Anna Rydén, Stephanie Chen, Emuella Flood, Beverly Romero, Susan Grandy
INTRODUCTION: Methods for discrete choice experiment (DCE) attribute and attribute-level selection have not yet been firmly established and are rarely reported in detail. This paper describes a qualitative study designed to inform the development of a DCE survey designed to examine preferences for glucagon-like peptide-1 receptor agonist (GLP-1RA) treatments among patients with type 2 diabetes mellitus. METHODS: The study involved a literature review, interviews with clinical experts, and interviews with GLP-1RA-experienced (i...
March 17, 2017: Patient
https://www.readbyqxmd.com/read/28315170/meeting-the-challenge-of-the-psychonomic-society-s-2012-guidelines-on-statistical-issues-some-success-and-some-room-for-improvement
#9
Peter E Morris, Catherine O Fritz
The Psychonomic Society (PS) adopted New Statistical Guidelines for Journals of the Psychonomic Society in November 2012. To evaluate changes in statistical reporting within and outside PS journals, we examined all empirical papers published in PS journals and in the Experimental Psychology Society journal, The Quarterly Journal of Experimental Psychology (QJEP), in 2013 and 2015, to describe these populations before and after effects of the Guidelines. Comparisons of the 2013 and 2015 PS papers reveal differences associated with the Guidelines, and QJEP provides a baseline of papers to reflect changes in reporting that are not directly influenced by the Guidelines...
March 17, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28314558/a-patient-and-provider-research-agenda-on-diabetes-and-hypertension-management
#10
Emily B Zimmerman, Sarah K Cook, Amber D Haley, Steven H Woolf, Sarah K Price, Danielle Berman, Thomas DeLeire, Rebecca Etz, Jag Khalsa, Kirsten Knutson, Kathryn Kolasa, Alex Krist, Anton Kuzel, Pearl Lee, Theresa J Nartea, Gretchen Piatt, Hilary Seligman, Joni Strom Williams, Josh Brown, Jennifer Early, Jill Hellman, Julie Karr, Megan Kervin, Isra Malik, Albert Walker, Sheila Goode, Danita Gregory, Sharon Herman, Brenda Kenney, Chimere Miles, Audrey Smith, Travis White
INTRODUCTION: A demonstration project in Richmond, Virginia involved patients and other stakeholders in the creation of a research agenda on dietary and behavioral management of diabetes and hypertension. Given the impact of these diseases on morbidity and mortality, considerable research has been directed at the challenges patients face in chronic disease management. The continuing need to understand disparities and find evidence-based interventions to improve outcomes has been fruitful, but disparities and unmet needs persist...
March 14, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28314185/nurse-students-learning-acute-care-by-simulation-focus-on-observation-and-debriefing
#11
Anna Abelsson, Birgitta Bisholt
INTRODUCTION: Simulation creates the possibility to experience acute situations during nursing education which cannot easily be achieved in clinical settings. AIM: To describe how nursing students learn acute care of patients through simulation exercises, based on observation and debriefing. DESIGN: The study was designed as an observational study inspired by an ethnographic approach. METHOD: Data was collected through observations and interviews...
March 9, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/28314093/clinical-impact-of-pharmacogenetic-guided-treatment-for-patients-exhibiting-neuropsychiatric-disorders-a-randomized-controlled-trial
#12
Marilyn C Olson, Alejandra Maciel, Jean Francois Gariepy, Ali Cullors, Juan-Sebastian Saldivar, David Taylor, Joel Centeno, Jorge A Garces, Sandeep Vaishnavi
Objective: Pharmacogenetic testing holds promise as a personalized medicine tool by permitting individualization of pharmacotherapy in accordance with genes influencing therapeutic response, side effects, and adverse events. The authors evaluated the effect on outcomes for patients diagnosed with neuropsychiatric disorders of pharmacogenetics (PGx)-guided treatment compared to usual standard of care. Methods: This was a prospective, randomized study of 237 patients at an outpatient community-based psychiatric practice conducted between April 2015 and October 2015...
March 16, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/28306695/lung-ultrasonography-a-practical-guide-for-cardiologists
#13
Francesco Bianco, Valentina Bucciarelli, Fabrizio Ricci, Raffaele De Caterina, Sabina Gallina
Lung ultrasonography is a well established, user-friendly and easy-to-use technique that can be used in the evaluation of several pathological conditions affecting the lung. Adding lung ultrasonography to traditional echocardiography provides an integrated cardiopulmonary ultrasound analysis. The simultaneous collection of information about the heart and the lungs can help physicians to investigate acute and chronic cardio-pulmonary conditions within a noninvasive, single-probe and all-in-one examination, not exposing the patient to the danger of ionizing radiation...
March 16, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28306597/diagnosis-of-viral-hepatitis
#14
Philippa J Easterbrook, Teri Roberts, Anita Sands, Rosanna Peeling
PURPOSE OF REVIEW: Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections and HIV-HBV and HCV coinfection are major causes of chronic liver disease worldwide. Testing and diagnosis is the gateway for access to both treatment and prevention services, but there remains a large burden of undiagnosed infection globally. We review the global epidemiology, key challenges in the current hepatitis testing response, new tools to support the hepatitis global response (2016-2020 Global Hepatitis Health Sector strategy, and 2017 WHO guidelines on hepatitis testing and their key recommendations) and future directions and innovations in hepatitis diagnostics...
March 16, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28306518/biochemical-testing-in-a-laboratory-tent-and-semi-intensive-care-of-ebola-patients-on-site-in-a-remote-part-of-guinea-a-paradigm-shift-based-on-a-bleach-sensitive-point-of-care-device
#15
Leonid M Irenge, Jean-Michel Dindart, Jean-Luc Gala
BACKGROUND: During the West Africa Ebola virus disease (EVD) outbreak, a Belgian laboratory was deployed for supporting the Ebola treatment unit (ETU) of N'Zerekore, Guinea. Besides diagnosis of EVD and malaria, biochemical parameters were tested and used to guide supportive treatment of EVD. METHODS: To preserve analytes stability, lithium-heparin blood samples were analyzed using the i-STAT® point-of-care testing (POCT) handheld device without the viral inactivation step...
March 15, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28306417/the-management-and-outcome-for-patients-with-chronic-subdural-hematoma-a-prospective-multicenter-observational-cohort-study-in-the-united-kingdom
#16
Paul M Brennan, Angelos G Kolias, Alexis J Joannides, Jonathan Shapey, Hani J Marcus, Barbara A Gregson, Patrick J Grover, Peter J Hutchinson, Ian C Coulter
OBJECTIVE Symptomatic chronic subdural hematoma (CSDH) will become an increasingly common presentation in neurosurgical practice as the population ages, but quality evidence is still lacking to guide the optimal management for these patients. The British Neurosurgical Trainee Research Collaborative (BNTRC) was established by neurosurgical trainees in 2012 to improve research by combining the efforts of trainees in each of the United Kingdom (UK) and Ireland's neurosurgical units (NSUs). The authors present the first study by the BNTRC that describes current management and outcomes for patients with CSDH throughout the UK and Ireland...
March 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28304079/endoscope-or-microscope-guided-pediatric-tympanoplasty-comparison-of-grafting-technique-and-outcome
#17
Adrian L James
OBJECTIVES/HYPOTHESIS: To review experience from the introduction of totally endoscopic ear surgery (TEES) to a pediatric tympanoplasty practice to identify factors influencing technique selection and successful outcome. STUDY DESIGN: Prospective cohort study. METHODS: Analysis of prospectively acquired data from a consecutive series of 295 surgeries for tympanic membrane perforation over a 12-year period. Success of perforation closure was compared between microscope and TEES grafting techniques...
March 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28303728/how-can-we-overcome-neuropsychological-adverse-effects-of-antiepileptic-drugs
#18
Juri-Alexander Witt, Christoph Helmstaedter
Antiepileptic pharmacotherapy can have a negative or positive impact on cognition and behavior. Besides individual susceptibilities (in terms of idiosyncratic reactions), the risk of adverse drug effects largely depends on treatment decisions. Therefore practical strategies to prevent neuropsychological side effects comprise (1.) selecting antiepileptic drugs (AEDs) with superior neuropsychological side effect profiles, (2.) restricting the individual drug load (target doses and number of concurrent AEDs), (3...
March 17, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28303520/the-intra-procedural-cortisol-assay-during-adrenal-vein-sampling-rationale-and-design-of-a-randomized-study-i-padua
#19
Maurizio Cesari, Giulio Ceolotto, Giacomo Rossitto, Giuseppe Maiolino, Teresa Maria Seccia, Gian Paolo Rossi
INTRODUCTION: Adrenal vein sampling (AVS) is the gold standard test for the subtyping of primary aldosteronism (PA). This procedure is hampered by unsuccessful bilateral cannulation of adrenal veins in up to two thirds of the cases depending on the cutoff of the selectivity index used. The rapid intra-procedural cortisol assay (IRCA) can increase the rate of bilateral success of AVS. This hypothesis needs to be proven using a randomized prospective study approach. AIM: We will therefore evaluate if an IRCA guiding adrenal vein sampling can increase the rate of selectivity and success of adrenal vein catheterization...
March 16, 2017: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
https://www.readbyqxmd.com/read/28303110/evaluating-intervention-programs-with-a-pretest-posttest-design-a-structural-equation-modeling-approach
#20
Guido Alessandri, Antonio Zuffianò, Enrico Perinelli
A common situation in the evaluation of intervention programs is the researcher's possibility to rely on two waves of data only (i.e., pretest and posttest), which profoundly impacts on his/her choice about the possible statistical analyses to be conducted. Indeed, the evaluation of intervention programs based on a pretest-posttest design has been usually carried out by using classic statistical tests, such as family-wise ANOVA analyses, which are strongly limited by exclusively analyzing the intervention effects at the group level...
2017: Frontiers in Psychology
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