keyword
MENU ▼
Read by QxMD icon Read
search

Pulse

keyword
https://www.readbyqxmd.com/read/28109139/-imiquimod-combined-with-dendritic-cell-vaccine-decreases-treg-proportion-and-enhances-anti-tumor-responses-in-mice-bearing-melanoma
#1
Shurong Ren, Qiubo Wang, Yanli Zhang, Cuixiu Lu, Ping Li, Yumei Li
Objective To investigate the therapeutic effect of Toll-like receptor 7 (TLR7) agonist imiquimod combined with dendritic cell (DC)-based tumor vaccine on melanoma in mice and the potential mechanism. Methods Melanoma-bearing mouse models were established by subcutanous injection of B16-OVA cells into C57BL/6 mice. DCs were isolated from mouse bone marrow and propagated in culture medium with recombinant mouse granulocyte-macrophage colony-stimulating factor (rmGM-CSF) and recombinant mouse interleukin-4 (rmIL-4)...
February 2017: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/28109132/echocardiographic-assessment-of-left-ventricular-function-in-healthy-horses-and-in-horses-with-heart-disease-using-pulsed-wave-tissue-doppler-imaging
#2
T R Koenig, K J Mitchell, C C Schwarzwald
BACKGROUND: Assessment of left ventricular (LV) function by tissue Doppler imaging (TDI) is not well established in horses with heart disease. OBJECTIVES: To describe the use of pulsed-wave (PW) TDI for the assessment of LV function, establish reference intervals, investigate effects of mitral regurgitation (MR), aortic regurgitation (AR), and primary myocardial disease (MD), and provide proof of concept for the use of PW TDI in Warmblood horses with heart disease...
January 21, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28108854/elective-icp-monitoring-how-long-is-long-enough
#3
S D Thompson, A Coutts, C L Craven, A K Toma, L W Thorne, L D Watkins
BACKGROUND: Intracranial pressure monitoring is commonly undertaken to assess and manage acute patients following head injury. However, ICP monitoring can also be a useful diagnostic tool in the management of CSF dynamics in elective patients. To date, there is little published research to suggest how long these elective patients require ICP monitoring in order to gain an accurate picture of a patient's ICP dynamics. At the author's institution, a minimum of 48-h data collection is currently undertaken in patients with a suspected ICP abnormality...
January 20, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28108357/sigma-1-receptor-deficiency-reduces-gabaergic-inhibition-in-the-basolateral-amygdala-leading-to-ltd-impairment-and-depressive-like-behaviors
#4
Baofeng Zhang, Ling Wang, Tingting Chen, Juan Hong, Sha Sha, Jun Wang, Hang Xiao, Ling Chen
Sigma-1 receptor knockout (σ1R-/-) in male mice causes depressive-like phenotype. We observed the expression of σ1R in principal neurons of basolateral amygdala (BLA), a main region for affective regulation. The present study investigated the influence of σ1R deficiency in BLA neurons on synaptic properties and plasticity at cortico-BLA pathway. In comparison with wild-type (WT) mice, the slopes of field excitatory postsynaptic potentials (fEPSP) were reduced in σ1R-/- mice with the increases in paired-pulse facilitation (PPF) and paired-pulse inhibition (PPI) values...
January 17, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28108331/recovery-cycle-of-inferior-collicular-neurons-in-hipposideros-pratti-under-behavior-related-sound-stimulus-and-the-best-doppler-shift-compensation-conditions
#5
Jia Tang, Chen-Xue Wei, Meng-Xia Chen, Qiao-Chao Wang, Hui-Fang Kong, Zi-Ying Fu, Qi-Cai Chen
The Doppler-shift compensation (DSC) behavior of constant frequency - frequency modulation (CF-FM) bat (Hipposideros pratti) is vital for extraction and analysis of echo information. This type of behavior affects the recovery cycles of sound-sensitive neurons, but their precise relationship remains unclear. In this study, we investigated the effects of DSC on the recovery cycles of inferior collicular (IC) neurons in H. pratti. We simulated the pulse-echo pair in bats by changing the emitted pulse frequency and keeping the echo frequency constant during DSC in echolocation...
January 18, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28107937/calibration-free-quantitative-analysis-of-elemental-ratios-in-intermetallic-nanoalloys-and-nanocomposites-using-laser-induced-breakdown-spectroscopy-libs
#6
Seyyed Ali Davari, Sheng Hu, Dibyendu Mukherjee
Intermetallic nanoalloys (NAs) and nanocomposites (NCs) have increasingly gained prominence as efficient catalytic materials in electrochemical energy conversion and storage systems. But their morphology and chemical compositions play critical role in tuning their catalytic activities, and precious metal contents. While advanced microscopy techniques facilitate morphological characterizations, traditional chemical characterizations are either qualitative or extremely involved. In this study, we apply Laser Induced Breakdown Spectroscopy (LIBS) for quantitative compositional analysis of NAs and NCs synthesized with varied elemental ratios by our in-house built pulsed laser ablation technique...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107933/graphene-like-carbon-nanosheets-as-a-new-electrode-material-for-electrochemical-determination-of-hydroquinone-and-catechol
#7
Hongmei Jiang, Shuqin Wang, Wenfang Deng, Youming Zhang, Yueming Tan, Qingji Xie, Ming Ma
We report here graphene-like carbon nanosheets (GCN) as a new electrode material for the electrochemical determination of hydroquinone (HQ) and catechol (CC). The GCN were prepared from maltose using ammonia chloride as a blowing agent and cobalt nitrate as a graphitization catalyst precursor. The as-prepared GCN material shows high graphitization degree, abundant porosity, and large specific surface area. Two well-separated anodic peaks for HQ and CC are obtained at GCN modified glassy carbon electrode (GCE) with a peak-to-peak separation of 118mV...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107929/highly-sensitive-aptasensor-based-on-synergetic-catalysis-activity-of-mos2-au-he-composite-using-cdna-au-god-for-signal-amplification
#8
Hai-Yan Song, Tian-Fang Kang, Li-Ping Lu, Shui-Yuan Cheng
Single or few-layer nanosheets of MoS2 (MoS2 nanosheets) and a composite composed of MoS2 nanosheets, Au nanoparticles (AuNPs) and hemin (HE) (denoted as MoS2-Au-HE) were prepared. The composites possessed high synergetic catalysis activity towards the electroreduction of hydrogen peroxide. Furthermore, glucose oxidase (GOD) and AuNPs were used as marker of the complementary DNA (cDNA) strand of kanamycin aptamer to prepare a conjugate (reffered as cDNA-Au-GOD) that was designed as the signal probe. Both cDNA-Au-GOD and MoS2-Au-HE were applied to fabricate aptasensor for kanamycin...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107914/development-of-amino-functionalized-carbon-coated-magnetic-nanoparticles-and-their-application-to-electrochemical-detection-of-hybridization-of-nucleic-acids
#9
Cansu Altay, R Hilal Senay, Ece Eksin, Gulsah Congur, Arzum Erdem, Sinan Akgol
In our study, the development of amino functionalized carbon coated magnetic nanoparticles (NH2-CC-MNPs) and their usage for electrochemical detection of hybridization of nucleic acids have been aimed. Firstly, NH2-CC-MNPs were prepared by coating of pristine Fe3O4 nanoparticles with two layers via caramelization and silanization processes respectively. After the morphological characterization with scanning electron microscopy (SEM) it was seen that NH2-CC-MNPs was spherical shaped and in 28nm sized. Investigation of chemical composition with the help of scanning electron microscopy/energy dispersive X-ray spectroscopy (SEM/EDX) and fourier transform infrared spectroscopy (FTIR) was showed incorporation of carbon and APTES to the structure of NH2-CC-MNPs...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107905/a-multi-walled-carbon-nanotubes-based-molecularly-imprinted-polymers-electrochemical-sensor-for-the-sensitive-determination-of-hiv-p24
#10
Ya Ma, Xiao-Lei Shen, Qiang Zeng, Hai-Shui Wang, Li-Shi Wang
To develop a rapid, simple and sensitive method for the determination of human immunodeficiency virus p24 (HIV-p24), a novel molecularly imprinted polymers (MIPs) electrochemical sensor was constructed on the surface of a multi-walled carbon nanotubes (MWCNTs) modified glassy carbon electrode (GCE) by surface polymerization using acrylamide (AAM) as functional monomer, N,N'-methylenebisacrylamide (MBA) as cross-linking agent and ammonium persulphate (APS) as initiator. Each modification step was carefully examined by cyclic voltammetry (CV), differential pulse voltammetry (DPV) and scanning electron microscope (SEM)...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107690/time-domain-nmr-as-a-new-process-monitoring-method-for-characterization-of-pharmaceutical-hydrates
#11
Stefanie Ulrike Schumacher, Benno Rothenhäusler, Alf Willmann, Jürgen Thun, Regina Moog, Martin Kuentz
Hydrates are of great pharmaceutical relevance and even though they have been characterized thoroughly by various analytical techniques, there is barely literature available on molecular mobility of the hydrate water studied by NMR relaxation in the time domain. The aim of this work was to examine the possibility of differentiating hydration states of drugs by (1)H time domain NMR (TD-NMR) regarding spin-spin and spin-lattice relaxation times (T2 and T1) using benchtop equipment. Caffeine and theophylline were selected as model compounds and binary mixtures of hydrate to anhydrate were analyzed for each drug using a spin echo and inversion recovery pulse sequence...
January 9, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28107035/determination-of-the-zinc-concentration-in-human-fingernails-using-laser-induced-breakdown-spectroscopy
#12
Vlora A Riberdy, Christopher J Frederickson, Steven J Rehse
The absolute concentration of Zn in human fingernail clippings was determined ex vivo using 1064 nm laser-induced breakdown spectroscopy and confirmed by speciated isotope dilution mass spectrometry. A nail testing protocol that sampled across the nail (perpendicular to the direction of growth) was developed and validated by scanning electron microscopy energy-dispersive X-ray spectrometry. Using this protocol, a partial least squares (PLS) regression model predicted the Zn concentration in the fingernails of five people to within an average of 7 ppm...
January 1, 2017: Applied Spectroscopy
https://www.readbyqxmd.com/read/28107011/delocalization-of-coherent-triplet-excitons-in-linear-rigid-rod-conjugated-oligomers
#13
Christian Hintze, Patrick Korf, Frank Degen, Friederike Schütze, Stefan Mecking, Ulrich E Steiner, Malte Drescher
In this work, the triplet state delocalization in a series of monodisperse oligo(p-phenyleneethynylene)s (OPEs) is studied by pulsed electron paramagnetic resonance (EPR) and pulsed electron nuclear double resonance (ENDOR) determining zero-field splitting, optical spin polarization, and proton hyperfine couplings. Neither the zero-field splitting parameters nor the optical spin polarization change significantly with OPE chain length, in contrast to the hyperfine coupling constants, which showed a systematic decrease with chain length n according to a 2/(1+n) decay law...
January 20, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28106949/atherectomy-using-a-solid-state-laser-at-355-nm-wavelength
#14
Amir Herzog, Grzegorz Oszkinis, David Planer, Krzysztof Ziaja, Łukasz Kruszyna, Michał Goran Stanisić, Damian Ziaja, Amiel A Ishaaya, Wacław Kuczmik
Peripheral arterial disease (PAD), caused by atherosclerotic processes, is allied with an increased risk of ischemic events, limb loss, and death. Recently, the use of a solid-state laser at 355 nm within a hybrid catheter was suggested for that purpose. In this work, short nanosecond pulses of a solid-state laser at 355 nm delivered through a hybrid catheter, composed of optical fibers and a blunt mechanical blade, are used to conduct a pre-clinical study and two clinical cases. The pre-clinical study consisted of an atherosclerotic calcified cadaveric leg and a porcine in vivo trial within the iliac artery, respectively...
January 20, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28106791/dietary-patterns-in-relation-to-cardiovascular-disease-incidence-and-risk-markers-in-a-middle-aged-british-male-population-data-from-the-caerphilly-prospective-study
#15
Elly Mertens, Oonagh Markey, Johanna M Geleijnse, David Ian Givens, Julie A Lovegrove
Dietary behaviour is an important modifiable factor in cardiovascular disease (CVD) prevention. The study aimed to identify dietary patterns (DPs) and explore their association with CVD incidence and risk markers. A follow-up of 1838 middle-aged men, aged 47-67 years recruited into the Caerphilly Prospective Cohort Study at phase 2 (1984-1988) was undertaken. Principal component analysis identified three DPs at baseline, which explained 24.8% of the total variance of food intake. DP1, characterised by higher intakes of white bread, butter, lard, chips and sugar-sweetened beverages and lower intake of wholegrain bread, was associated with higher CVD (HR 1...
January 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28106748/two-dimensional-numerical-simulations-of-ultrasound-in-liquids-with-gas-bubble-agglomerates-examples-of-bubbly-liquid-type-acoustic-metamaterials-blamms
#16
Christian Vanhille
This work deals with a theoretical analysis about the possibility of using linear and nonlinear acoustic properties to modify ultrasound by adding gas bubbles of determined sizes in a liquid. We use a two-dimensional numerical model to evaluate the effect that one and several monodisperse bubble populations confined in restricted areas of a liquid have on ultrasound by calculating their nonlinear interaction. The filtering of an input ultrasonic pulse performed by a net of bubbly-liquid cells is analyzed. The generation of a low-frequency component from a single cell impinged by a two-frequency harmonic wave is also studied...
January 17, 2017: Sensors
https://www.readbyqxmd.com/read/28106664/ethnic-differences-regarding-arterial-stiffness-of-6-8-year-old-black-and-white-boys
#17
Gontse G Mokwatsi, Aletta E Schutte, Ruan Kruger
OBJECTIVES: Vascular deterioration is suggested to occur earlier in black than white populations, thereby increasing their risk for developing hypertension. To establish whether this is the case, we compared different estimates of arterial stiffness in black and white children and investigated the links with body composition and advanced glycation end products (AGEs) as potential contributors. METHODS: We included 40 black and 41 white boys (aged 6-8 years) from similar schools and measured arterial stiffness [pulse wave velocity (PWV) in different arterial sections, systemic arterial compliance and carotid stiffness estimates], anthropometry as well as urinary pentosidine as a marker of AGEs...
January 18, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28106663/the-role-of-laser-doppler-flowmetry-tests-serum-angiopoietin-2-asymmetric-and-symmetric-dimethylarginine-to-predict-outcome-in-chronic-kidney-disease
#18
János Nemcsik, Orsolya Cseprekál, József Egresits, Jan Kielstein, Philipp Kümpers, Alexander Lukasz, Ádám Tabák, Adrienn Marton, Zsófia K Németh, Zoltán Járai, Gabriella Godina, László Sallai, Katalin Farkas, István Kiss, András Tislér
OBJECTIVE: The role of biochemical and functional markers of microvascular dysfunction to predict cardiovascular outcomes in nondialyzed chronic kidney disease (CKD) remains unclear. In this prospective cohort study, we assessed whether biochemical [serum level of angiopoietin-2 (Ang-2), asymmetric and symmetric dimethylarginin] and functional (laser Doppler flowmetry) measures of microvascular function predicted cardiovascular events, cardiovascular and all-cause mortality in CKD patients...
January 18, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28106472/sample-preparation-for-repeated-measurements-on-a-single-liquid-droplet-using-laser-induced-breakdown-spectroscopy
#19
Violeta Lazic, Roberta Fantoni, Antonio Palucci, Massimiliano Ciaffi
We studied changes in laser-induced breakdown spectroscopy (LIBS) signal intensity with the thickness of a liquid layer placed on a solid substrate, where an easily evaporating methanol sample was used. For a certain optimal liquid film thickness we obtained a manifold increase of the LIBS signal from methanol. Progressive liquid film thinning leads to a reduction and a successive disappearance of laser-induced splashes; the latter condition drastically reduces the sample consumption and allows measurements to be repeated many times on a single liquid droplet...
January 1, 2017: Applied Spectroscopy
https://www.readbyqxmd.com/read/28106423/amplification-of-relativistic-electron-bunches-by-acceleration-in-laser-fields
#20
J Braenzel, A A Andreev, F Abicht, L Ehrentraut, K Platonov, M Schnürer
Direct acceleration of electrons in a coherent, intense light field is revealed by a remarkable increase of the electron number in the MeV energy range. Laser irradiation of thin polymer foils with a peak intensity of ∼1×10^{20}  W/cm^{2} releases electron bunches along the laser propagation direction that are postaccelerated in the partly transmitted laser field. They are decoupled from the laser field at high kinetic energies, when a second foil target at an appropriate distance prevents their subsequent deceleration in the declining laser field...
January 6, 2017: Physical Review Letters
keyword
keyword
117828
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"