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Sung-Il Baik, Dieter Isheim, David N Seidman
Atom-probe tomography (APT) is a unique analysis tool that enables true three-dimensional (3-D) analyses with sub-nano scale spatial resolution. Recent implementations of the local-electrode atom-probe (LEAP) tomograph with ultraviolet laser pulsing have significantly expanded the research applications of APT. The small field-of-view of a needle-shaped specimen with a less than 100 nm diam. is, however, a major limitation for analyzing materials. The systematic approaches for site-specific targeting of an APT nanotip in a transmission electron microscope (TEM) of a thin sample are introduced to solve the geometrical limitations of a sharpened APT nanotip...
October 12, 2017: Ultramicroscopy
Thomas Knackstedt, Nathaniel J Jellinek
No abstract text is available yet for this article.
October 19, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Sung-Eun Kim, Jun Ho Lee, Tae Gon Kim, Yong-Ha Kim, Kyu Jin Chung
BACKGROUND: Fat grafting is a commonly performed procedure not only for augmenting the soft tissue but also for regeneration in esthetic and reconstructive plastic surgery.However, unpredictable fat survival rate because of high resorption rate is remained as the main problem. The purpose of this study was to investigate the effect of pretreatment of the recipient site to the fat survival using fractional carbon dioxide (CO2) laser. METHODS: The rats were divided to 2 groups...
October 19, 2017: Annals of Plastic Surgery
Steven Kinio, James K Mills
This paper presents the design and experimental performance of a microelectrode-based device to selectively lyse cells in a flow in a microfluidic channel. Localized cell lysis is achieved by utilizing "irreversible electroporation", in which cells are exposed to high magnitude electric pulses. Localized cell lysis in a flow has research applications and may allow for removal of harmful cells such as circulating tumor cells from blood. Due to the dependence of this technique on the magnitude of the applied electric field, lethal electric field regions can be localized in the channel by calibration of the applied voltage...
October 17, 2017: IEEE Transactions on Nanobioscience
Lindsey A Crowe, Gibran Manasseh, Aneta Chmielewski, Anne-Lise Hachulla, Daniel Speicher, Andreas Greiser, Hajo Muller, Thomas De Perrot, Jean-Paul Vallee, Rares Salomir
OBJECTIVES: We demonstrate the use of a Magnetic-Resonance (MR)-compatible ultrasound (US) imaging probe using spatially-resolved Doppler for diagnostic quality cardiovascular MR imaging as an initial step towards hybrid US/MR fetal imaging. METHODS: A newly developed technology for a dedicated MR-compatible phased array ultrasound-imaging probe acquired pulsed color Doppler carotid images, which were converted in near-real time to a trigger signal for cardiac cine and flow quantification MRI...
October 17, 2017: IEEE Transactions on Bio-medical Engineering
Fabian Barras, Philippe H Geubelle, Jean-François Molinari
Using an elastodynamic boundary integral formulation coupled with a cohesive model, we study the problem of a dynamic rupture front propagating along an heterogeneous plane. We show that small-scale heterogeneities facilitate the supershear transition of a mode-II crack. The elastic pulses radiated during front accelerations explain how microscopic variations of fracture toughness change the macroscopic rupture dynamics. Perturbations of dynamic fronts are then systematically studied with different microstructures and loading conditions...
October 6, 2017: Physical Review Letters
Simone Gasparinetti, Marek Pechal, Jean-Claude Besse, Mintu Mondal, Christopher Eichler, Andreas Wallraff
We use a three-level artificial atom in the ladder configuration as a source of correlated, single microwave photons of different frequency. The artificial atom, a transmon-type superconducting circuit, is driven at the two-photon transition between ground and second-excited state, and embedded into an on-chip switch that selectively routes different-frequency photons into different spatial modes. Under continuous driving, we measure power cross-correlations between the two modes and observe a crossover between strong antibunching and superbunching, typical of cascade decay, and an oscillatory pattern as the drive strength becomes comparable to the radiative decay rate...
October 6, 2017: Physical Review Letters
Jaume Taura, Marta Valle-León, Kristoffer Sahlholm, Masahiko Watanabe, Katheleen Van Craenenbroeck, Víctor Fernández-Dueñas, Sergi Ferré, Francisco Ciruela
G protein-coupled receptors (GPCR) exhibit the ability to form receptor complexes that include molecularly different GPCR (i.e. GPCR heteromers), which endow them with singular functional and pharmacological characteristics. The relative expression of GPCR heteromers remains a matter of intense debate. Recent studies support that adenosine A2A receptors (A2A R) and dopamine D2 receptors (D2 R) predominantly form A2A R-D2 R heteromers in the striatum. The aim of the present study was evaluating the behavioral effects of pharmacological manipulation and genetic blockade of A2A R and D2 R within the frame of such a predominant striatal heteromeric population...
October 20, 2017: Genes, Brain, and Behavior
Meihua Bi, Yanan Hao, Jiameng Zhang, Ming Lei, Ke Bi
Polymer nanocomposites are a promising substitute for energy-storage dielectric materials in pulsed power systems. A barium titanate/polyvinylidenefluoride (BT/PVDF) nanocomposite is one of the most widely studied composite systems due to its comprehensive excellent dielectric properties. As the dielectric response of nanocomposites depends strongly on the size of the fillers, in this study, BT/PVDF nanocomposites with 92.3 nm, 17.8 nm and 5.9 nm BT particle fillers are fabricated to reveal the particle size effect of the fillers on the energy storage performance of the polymer nanocomposites...
October 20, 2017: Nanoscale
Guillaume Goudot, Tristan Mirault, Bastien Arnal, Catherine Boisson-Vidal, Bernard Le Bonniec, Pascale Gaussem, Alexandre Galloula, Mickael Tanter, Emmanuel Messas, Mathieu Pernot
Post-thrombotic syndrome, a frequent complication of deep venous thrombosis can be reduced with early vein recanalization. Pulsed cavitational therapy (PCT) using ultrasound is a recent non-invasive approach. We propose to test the efficacy and safety of high-frequency focused PCT for a drug-free thrombolysis (thrombotripsy) in a realistic in vitro model of venous thrombosis. To reproduce venous thrombosis conditions, human whole blood was allowed to clot by stasis in silicone tubes (6 mm internal diameter) at a 30 cmH20 pressure, maintained during the whole experiment...
October 20, 2017: Physics in Medicine and Biology
Mohsen Tagavifar, Ke Xu, Sung Hyun Jang, Matthew T Balhoff, Gary A Pope
The dynamic behavior of microemulsion-forming water-oil-amphiphiles mixtures is investigated in a 2.5-D micromodel. The equilibrium phase behavior of such mixtures is well understood in terms of macroscopic phase transitions. However, what is less understood and where experimental data are lacking is the coupling between the phase change and the bulk flow. Herein, we study flow of an aqueous surfactant solution-oil mixture in porous media and analyze the dependence of phase formation and spatial phase configurations on the bulk flow rate...
October 20, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
Charles Khouri, Sylvain Kotzki, Matthieu Roustit, Sophie Blaise, Francois Gueyffier, Jena-Luc Cracowski
Electrical stimulation (ES) has been tested for decades to improve chronic wound healing. However, uncertainty remains on the magnitude of the efficacy and on the best applicable protocol. We conducted an effect size meta-analysis to assess the overall efficacy of ES on wound healing, to compare the efficacy of the different modalities of electrical stimulation, and to determine whether efficacy differs depending on the wound etiology, size and age of the chronic wound. Twenty-nine randomized clinical trials with 1510 patients and 1753 ulcers were selected...
October 20, 2017: Wound Repair and Regeneration
Orhan Üreyen, Atahan Acar, Uğur Gökçelli, Murat Kemal Atahan, Enver İlhan
BACKGROUND: This study aimed to evaluate the usefulness of Fournier's gangrene scoring index (FGSI) and Uludag FGSI (UFGSI) for predicting mortality in patients with FG. METHODS: Patients who underwent treatment and follow-up in the A division department of general surgery at two education and research hospitals between January 2012 and December 2015 were evaluated for mortality-related factors. The sensitivities of FGSI and UFGSI scoring systems for predicting mortality-related factors and disease prognosis were evaluated...
September 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
Xu Chen, Wen Xu, Yandong Jiang, Gencai Pan, Donglei Zhou, Jinyang Zhu, He Wang, Cong Chen, Dongyu Li, Hongwei Song
Fabrication of near-infrared light-triggered photoelectrochemical (PEC) sensors based on the upconversion nanophosphors (UCNPs) is a novel approach, which exhibits the advantages of low background signal and non-damage to the biological substance as well as high sensitivity and improved electric detection in PEC sensors. Herein we demonstrate the preparation of novel and high-quality ZnO inverse opal photonic crystals (IOPCs)/Ag/NaYF4:Yb,Tm hybrid films by different advanced film techniques, including colloidal self-assembling, vapor phase deposition and pulsed laser deposition and its application to sensitive detection of alpha-fetoprotein (AFP)...
October 20, 2017: Nanoscale
Martin Lehr, Benjamin Foerster, Mathias Schmitt, Katja Krüger, Carsten Sönnichsen, Gerd Schönhense, Hans-Joachim Elmers
Electron emission by femtosecond laser pulses from individual Au nanorods is studied by a time-of-flight momentum resolving photoemission electron microscope (ToF k-PEEM). The Au nanorods adhere to a transparent indium-tin-oxide substrate allowing for illumination from the rear side at normal incidence. Localized plasmon polaritons are resonantly excited at 800 nm with 100 fs long pulses. The momentum distribution of emitted electrons reveals two distinct emission mechanisms: A coherent multiphoton photoemission process from the optically heated electron gas leads to an isotropic emission distribution...
October 20, 2017: Nano Letters
Rainer Hoffmann, Lukas Langenbrink, Doris Reimann, Mirlind Kastrati, Michael Becker, Michal Piatkowski, Jochen Michaelsen
BACKGROUND: Novel X-ray systems with real-time image noise reduction technology (INRT) to reduce radiation dose during fluoroscopy and cine acquisition have become available. This study evaluated the reduction of radiation dose in device implantation with INRT. METHODS: Radiation dose data from 132 consecutive new device implantation procedures (102 pacemaker (PM) or implantable cardioverter defibrillator (ICD) and 30 cardiac resynchronization therapy (CRT) devices) performed between 1-2015 and 12-2015 on an angiography system with INRT (Allura ClarityIQ) were collected...
October 20, 2017: Pacing and Clinical Electrophysiology: PACE
Iain M T Murray, Neil J Rowan, Sara McNamee, Katrina Campbell, Andrew M Fogarty
This constitutes the first study to report on the reduction in toxicity of the dinoflagellate algal toxin okadaic acid after novel pulsed light (PL) treatments where ecotoxicological assessment was performed using a miniaturised format of the conventional in vivo freshwater crustacean Daphnia sp. acute toxicity test. Bivalves accumulate this toxin, which can then enter the human food chain causing deleterious health effects such as diarrhetic shellfish poisoning. This miniaturised toxicological bioassay used substantially less sample volume and chemical reagents...
October 19, 2017: Environmental Science and Pollution Research International
M Farzan Rashid, Elizabeth M Hecht, Jonathan A Steinman, Michael D Kluger
Irreversible electroporation (IRE) is increasingly used for the ablation of unresectable locally advanced pancreatic adenocarcinoma. Unlike other ablation technologies that cannot be safely used around critical vasculature or ducts for risk of thermal damage, IRE uses high-voltage pulses to disrupt cellular membranes. This causes cell death by apoptosis and inflammation. IRE has been deployed by both open and percutaneous approaches. Generator parameters are the same for both approaches, and settings are pancreas specific...
October 19, 2017: Abdominal Radiology
Atchi Walla, Faré Gnandi-Piou, Pilakimwé Egbohou, Komi Assogba, Mawuko Quacoe
INTRODUCTION: The literature review revealed that nowadays only about 15 cases of bilateral shoulder dislocation associated with the fracture of the upper end of the humerus have been published. The triad of lesional mechanism designated by the triple syndrome E composed of epilepsy, electrocution, and external trauma was the circumstances noted in which these fractures dislocations occur with migration of the two humeral heads either forward or backward. CASE REPORT: An architect of 36-year-old, right-handed, was admitted in emergency department for loss of knowledge of progressive installation...
May 2017: Journal of Orthopaedic Case Reports
Assaf Gal, Sanja Sviben, Richard Wirth, Anja Schreiber, Benedikt Lassalle-Kaiser, Damien Faivre, André Scheffel
Many organisms form minerals from precursor phases that crystallize under strict biological control. The dynamic intracellular processes of formation, transport, and deposition of these precursor phases are challenging to identify. An unusual situation is recently revealed for the calcifying alga Emiliania huxleyi, as the cells contain a compartment filled with a concentrated Ca and P phase but the final calcite crystals, which are nucleated in a different compartment, are P-free. Thus, the connection of the Ca-P-rich pool to the mineralization process remains unclear...
October 2017: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
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